• Research in Community and Public Health Nursing
• /
• v.10 no.2
• /
• pp.307-319
• /
• 1999

The purpose of this study was to identify the major factors affecting performance in health promoting lifestyle of industrial workers. The subjects for this study 241 workers employed in S company in T city and were obtained by a convenience sample. Data were collected from March 2 to April 28. 1998. The collected data were analyzed using frequency. percent. mean. cronbach alpha. t-test. ANOVA. Person coefficients of correlation. Duncan test. stepwise multiple regression with an SPSS program. The results of this are summarized as follows. 1) The average score of performance in the health promoting lifestyle was 2.62. The variable with the highest degree of performance was harmonious relationship. whereas the one with the lowest degree was professional health maintenance. 2) Performance in the health promoting lifestyle was significantly correlated with self esteem, internal health locus of control and powerful others health locus of control. 3) Performance in the health promoting lifestyle was significantly correlated with such demographic variables as age. religion, education level. marital state. family number. types of dwelling. 4) The most important factor that affect performance in the health promoting lifestyle was powerful others health locus of control and self esteem. On the basis of this study. other factors affecting others health promoting lifestyle should be identified.

• Child Health Nursing Research
• /
• v.14 no.4
• /
• pp.396-404
• /
• 2008

Purpose: This study was conducted to identify the level of quality of family life, parental locus of control, and parental sense of competence, and to elucidate factors that influence family quality of life in the mothers of children with Attention Deficit/Hyperactive Disorder (ADHD). Method: A convenient sample of mothers from 6 child psychiatric clinics was used in this cross-sectional survey design. Questionnaires used for data collection included the following scales: Family Quality of Life, Parental Locus of Control-Short Form Revised, Parental Sense of Competence. Results: The level of family quality of life was mid-range. A positive relationship was found between Family Quality of Life and the research variables. The significant predictors of family quality of life were parental locus of control, parental sense of competence, and duration of medication and these variables accounted for 21.8% of the variance in family quality of life. Conclusions: These results indicate that family quality of life is an important factor which health care provider should assess and evaluate for children with ADHD and their families. The results of this study suggest that family quality of life is an important link with parental sense of competence and parental locus of control.

• Child Health Nursing Research
• /
• v.15 no.2
• /
• pp.182-189
• /
• 2009

Purpose: The purpose of this study was to identify the factors influencing health risk behavior in high school students. Methods: The subjects were 512 students from 4 high schools in 3 cities. The questionnaire measured the level of self-esteem, self-efficacy, internal locus of control and health risk behaviors. The data were analyzed using descriptive statistics, t-test, ANOVA, Scheffe test, Pearson's correlation coefficient and stepwise multiple regression analysis. Results: There were significant differences in the health risk behaviors according to sex, a classification of the school, whether or not smoking of mother, whether or not live alone, level of harmonious family, level of satisfying school-life and three variables of them were significant differences by Scheffe test. There was a significant positive correlation between sub-dimension of health risk behaviors and the self-efficacy, self-esteem, internal locus of control were negative correlation with health risk behaviors. The most important influential factor of the health risk behaviors was the self-efficacy. Conclusion: From the studies reviewed, improving the self-efficacy, self-esteem, internal locus of control and the general social environment of students will probably be the most effective strategies for primary prevention of health risk behaviors.

• Journal of Microbiology and Biotechnology
• /
• v.11 no.5
• /
• pp.763-771
• /
• 2001

Biphenyl dioxygenase (BPDO), which catalyzes the first step in the bacterial degradation of biphenyl and polychlorinated biphenyls, was characterized in Pseudomonas sp. B4. The bphA locus containing the four structural genes encoding BPDO were cloned and sequenced. A regulatory gene as well as a putative regulatory sequence were identified upstream of this locus. A transposase-like gene was found within a 1-kb region further upstream, thereby suggesting that the bphA locus may be carried on a transposable element. The three components of the BPDO enzyme have been separately overexpressed and purified from E. coli. The ferredoxin and terminal dioxygenase components showed biochemical properties comparable to those of two previously characterized BPDOs, whereas the ferredoxin reductase exhibited an unusually high lability. The substrate selectivity of BPDO was examined in vivo using resting cell assays performed with mixtures of selected polychlorinated biphenyls. The results indicated that para-substituted congeners were the preferred substrates. In vitro studies were carried out on a BPDO complex where the reductase from strain B4 we replaced by the more stable isoform from Comamonas testosteroni B-356. The BPDO enzyme had a specific activity of $0.26{\pm}0.02 {\mu}mol {min^-1}{mg^-1}\;of\;ISP_{BPH}$ with biphenyl as the substrate. The 2,3-, 4,4'-, and 2,4,4'-chlorobiphenyls were converted to single dihydrodiols, while 2,4'-dichlorobiphenyl gave rise to two dihydrodiols. The current data also indicated that 2,4,4'-trichlorobiphenyl was a better substrate than the 4,4'-dichlorinated congener.

• Journal of Korean Public Health Nursing
• /
• v.22 no.2
• /
• pp.224-236
• /
• 2008

Purpose: The principal objective of this study was to assess the relationships of depression, fatigue, BMI, and health locus of control between urban and rural female middle school students. Methods: The study subjects included 377 girls in randomly-sampled middle schools in urban and rural provinces. The data were collected via self-recorded questionnaires from April 21.- to May 2. 2008, and analyzed using the SPSS Win 12.0 program. Results; 1) The mean score of depression was $10.22{\pm}5.72$ (urban), $10.81{\pm}4.92$ (rural). 2) The mean fatigue score was $50.43{\pm}1.57$ (urban), $51.90{\pm}9.70$ (rural). 3) BMI was classified into 3 groups: leptosomic, normal weight, and obesity groups. The mean BMI score was $18.73{\pm}2.05$ (Seoul), and $20.31{\pm}3.26$ (provincial). 4) The internal locus of control was higher than the external locus of control (urban). 5) Fatigue was correlated with depression (r=.512, p=.000) in both areas. The health locus of control was correlated with Fatigue (r=.153, p=.042) in province. Conclusion: An effective program to reduce the levels of fatigue and depression for middle school girls and to maintain normal weight is required. In particular, the high-risk depression group can be managed through community mental health care center deep interviews, and close observation.

• Journal of the Korean Data and Information Science Society
• /
• v.18 no.4
• /
• pp.1103-1113
• /
• 2007

LOD scores and a permutation test for detecting and locating Quantitative trait loci(QTL) from the Hanwoo economic trait have been described and we selected a considerable major BMS941 locus. K -means clustering analysis of eight markers in BMS941 and four traits resulted in three cluster groups. Finally, we applied the bootstrap test method to calculate confidence intervals for finding major DNA markers. We conclude that the major markers of BMS941 locus in Hanwoo chromosome 17 are markers 85bp and 105bp.

• KSBB Journal
• /
• v.18 no.3
• /
• pp.207-210
• /
• 2003

The locus coeruleus (LC) contains about half of the total number of noradrenergic neurons in the brain and those noradrenergic neurons from the LC innervate entire brain regions. The LC is a major common target region in several neurodegenerative disorders such as Alzheimer's, Pakinson's and Huntington's diseases. The brain-derived neurotrophic factor (BDNF) regulate neuronal cell survival and differentiation of central nervous system neurons, including LC noradrenergic neurons. In this study, various small molecules and growth factors were tested as candidates to promote the production of BDNF in LC noradrenergic neuronal cells. The molecules tested include neuropeptides, cytokines, growth factors, neurotransmitters, and intracellular signaling agents. Four small molecules or growth factors, FGF8b, BMP-4, forskolin, and dibutyryl cGMP, were found to increase the release of BDNF in LC noradrenergic neurons. Especially, BMP-4 significantly enhanced BDNF production over 2.5-fold in LC noradrenergic neurons.

• Journal of Microbiology
• /
• v.38 no.1
• /
• pp.18-23
• /
• 2000

Streptomyces coelicolor produces three kinds of catalases to cope with oxidative stress and to allow normal differentiation. Catalase A is the major vegetative catalase which functions in removing hydrogen peroxide generated during the process of aerobic metabolism. To understand the regulatory mechanism of response against oxidative stress, hydrogen peroxide-resistant mutant (HR4O) was isolated from S. coelicolor J1501 following UV mutagenesis. The mutant overproduced catalase A more than 50-fo1d compared with the wild type. The mutation locus catRI was mapped closed to the mthB2 locus by genetic crossings. An ordered cosmid library of S. coelicolor encompassing the mthB2 locus was used to isolate the regulator gene (catR) which represses catalase overproduction when introduced into HR4O. A candidate catR gene was found to encode a Fur-like protein of 138 amino acids (15319 Da).

• Journal of Korean Public Health Nursing
• /
• v.13 no.2
• /
• pp.45-58
• /
• 1999

This study was conducted to compare the practice of health promoting behaviors between hospital workers and government officers. The subjects for this study were consisted of 344 hospital workers in four university hospitals and 340 government officers in four district offices in the Kyong-in area. Data were collected by using constructed questionnaires from January to February in 1997 and analyzed by Chi-square test, t-test. ANOVA, Pearson correlation coefficient and stepwise multiple regression. The results were as follows : 1. There was no significant difference between hospital workers and government officers in practice of health promoting behaviors as a whole. but among five domains of the health promoting behaviors, hospital workers was significantly higher than that of government officer in the domain of health responsibility, while they were significantly lower than those of government officer in the domain of exercise & nutrition and stress management. The mean score of health promoting behavior for hospital workers and government officer were 2.40, and 2.47, respectively. The health promoting behavior in relation to the characteristics of the hospital workers varied significantly according to sex and age. The domain of self-actualization ranked highest in health promoting behaviors of hospital workers, interpersonal support came next. stress management, health responsibility and exercise & nutrition followed them. While those of government officers. the domain of self-actualization ranked highest. interpersonal support came next, stress management, exercise & nutrition and health responsibility followed them. 2. There were no significant difference between hospital workers and government officers in the health perception with mean score of 3.32 and 3.34 respectively, in the self esteem with mean score of 2.82 and 2.84 respectively, in the self-efficacy with mean score of 70.50 and 72.35 respectively. in the internal health locus of control with mean score of 2.95 and 3.03, respectively, m the chance health locus of control with mean score of 2.10 and 2.13, respectively, m the powerful others health locus of control with mean score of 2.39 and 2.46, respectively. 3. The practice of health promoting behavior of hospital workers were strongly associated with self-esteem and self-efficacy, and self-esteem was strongly correlated with self-efficacy. And the practice of health promoting behavior of government officers were strongly associated with self-esteem, powerful others health locus of control and internal health locus of control. and self-esteem was strongly correlated with self-efficacy. 4. The combination of self-esteem, powerful others health locus of control. health perception. self-efficacy. internal health locus of control. age and marital status explained $45.7\%$ of variance of likelihood to engage in health promoting behavior of hospital workers. And the combination of self-esteem. powerful others health locus of control. health perception. self-efficacy. internal health locus of control. sex and marital status explained $48.2\%$ of variance of likelihood to engage in health promoting behavior of government officers.

• Korean Journal of Occupational Health Nursing
• /
• v.7 no.1
• /
• pp.20-32
• /
• 1998

This study was conducted investigate the practice of health promoting behavior in hospital workers. The subjects for this study were 529 hospital war kern working in four university hospitals in the Kyong-in area. Data were collected by using constructed questionnaires from January 13. 1997 to February 24, 1997, analyzed by descriptive statistics, ANOVA and $Scheff{\acute{e}}$ comparison test, Pearson's correlation coefficient and stepwise multiple regression. The results were as follows; 1. The mean score of health promoting behavior for hospital workers was 2.40. The health promoting behavior in relation to the characteristics of the subjects varied significantly according to sex, age, career, religion and number of children. 2. The mean score of health perception was 3.29. The health perception in relation to the characteristics of the subjects showed no statistical discrepancy. 3. The mean score of self-esteem was 3.80. The self-esteem in relation to the characteristics of the subjects varied significantly according to sex, age, occupation, educational background, religion and marital status. 4. The mean score of self-efficacy was 69.63. The self-efficacy in relation to the characteristics of the subjects sailed significantly according ding to sex, age, occupation, career, religion, marital status and number of children. 5. The mean score of internal health locus of control was 2.88. The internal health locus of control in relation to the characteristics of the subjects varied significantly according to sex and occupation. The mean score of chance health locus of control was 2.08. The chance health locus of control in relation to the characteristics of the subjects varied significantly according to occupation and religion. The mean score of powerful others health locus of control was 2.35. The powerful others health locus of control in relation to the characteristics of the subjects varied significantly according to career, educational background, marital status and number of children. 6. Performance in health promoting behavior was significantly correlated with self-esteem, self-efficacy, powerful others health locus of control, health perception and internal health locus of control. 7. The combination of self-esteem, powerful others health locus of control, health perception, self-efficacy, internal health lot-us of control, age and marital status explained 45.72% of the variance of likelihood to engage in health promoting behavior.