• Journal of Microbiology and Biotechnology
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• 제24권11호
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• pp.1495-1502
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• 2014

Metarhizium anisopliae is a widely studied model to understand the virulence factors that participate in pathogenicity. Proteases such as subtilisin-like enzymes (Pr1) and trypsin-like enzymes (Pr2) are considered important factors for insect cuticle degradation. In four M. anisopliae strains (798, 6342, 6345, and 6347), the presence of pr1 and pr2 genes, as well as the enzymatic activity of these genes, was correlated with their virulence against two different insect pests. The 11 pr1 genes (A, B, C, D, E, F, G, H, I, J, and K) and pr2 gene were found in all strains. The activity of individual Pr1 and Pr2 proteases exhibited variation in time (24, 48, 72, and 96 h) and in the presence or absence of chitin as the inductor. The highest Pr1 enzymatic activity was shown by strain 798 at 48 h with chitin. The highest Pr2 enzymatic activity was exhibited by the 6342 and 6347 strains, both grown with chitin at 24 and 48 h, respectively. Highest mortality on S. exigua was caused by strain 6342 at 48 h, and strains 6342, 6345, and 6347 caused the highest mortality 7 days later. Mortality on Prosapia reached 30% without variation. The presence of subtilisin and trypsin genes and the activity of these proteases in M. anisopliae strains cannot be associated with the virulence against the two insect pests. Probably, subtilisin and trypsin enzyme production is not a vital factor for pathogenicity, but its contribution is important to the pathogenicity process.

• Steel and Composite Structures
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• 제22권4호
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• pp.745-752
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• 2016

An investigation has been done to study the evolution of the microstructure, mechanical and electrical properties of AlMgSi alloy destined for the transport of electric energy, in function of the deformation caused by the cold drawing process. We identified that drawing of aluminum wire causes development of a fibrous texture of type <111> and <100>. We notice also that the electrical resistivity and mechanical resistance increases with the increasing of the deformation level. Characterization methods used in this work is: The Electron Back Scattered Diffraction EBSD, X-Ray diffraction, Vickers microhardness, Tensile test, Measuring electrical resistivity, the Scanning Electron Microscope (SEM) and Energy Diffraction Spectrum (EDS).

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.947-952
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• 2015

The aim of this study was to evaluate the effects of grape juice on colon carcinogenesis induced by azoxymethane (AOM) and expression of NF-kB, iNOS and TNF-${\alpha}$. Methods: Forty male Wistar rats were divided into 7 groups: G1, control; G2, 15 mg/kg AOM; G3, 1% grape juice 2 weeks before AOM; G4, 2% grape juice 2 weeks before AOM; G5, 1% grape juice 4 weeks after AOM; G6, 2% grape juice 4 weeks after AOM; G7, 2% grape juice without AOM. Histological changes and aberrant crypt foci (ACF) were studied, while RNA expression of NF-kB, TNF- and iNOS was evaluated by qPCR. Results: The number of ACF was higher in G2, and G4 presented a smaller number of crypts per focus than G5 (p=0.009) and G6. Small ACF (1-3) were more frequent in G4 compared to G2, G5 and G6 (p=0.009, p=0.009 and p=0.041, respectively). RNA expression of NF-kB was lower in G3 and G4 compared to G2 (p=0.004 and p=0.002, respectively). A positive correlation was observed between TNF-${\alpha}$ and NF-kB gene expression (p=0.002). In conclusion, the administration of 2% grape juice before AOM reduced the crypt multiplicity, attenuating carcinogenesis. Lower expression of NF-kB was observed in animals exposed to grape juice for a longer period of time, regardless of concentration.

• 한국수학사학회지
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• 제17권2호
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• pp.73-84
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• 2004

스톤은 스톤 쌍대성에 의하여 완비 불 대수는 극단적으로 비연결인 콤팩트 하우스도르프 공간에 대응되어 불 대수의 범주 Bool에서 단사 대상은 완비 불 대수인 사실에 의하여 0차원 콤팩트 공간의 범주 ZComp의 사영 대상은 극단적으로 비연결인 콤팩트 공간임을 증명하였고, 완전 정규 공간 X가 극단적인 비연결 공간이기 위한 필요충분조건은 X에서 실직선로의 연속함수의 순서집합 C(X, )이 데데킨트 완비인 사실[6]이 드모르간 틀에서도 성립함을 증명하였다[2]. 이 논문에서는 드 모르간의 역사를 조사하고, 드모르간 틀을 도입하여 극단적인 비연결 공간과의 관계와 드 모르간 틀과 불 대수 사이의 관계를 연구한다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.891-894
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• 2013

The present study was performed to assess the activity of the botulinum toxin A on breast cancer cells. The T47D cell line was exposed to diverse concentrations of the botulinum toxin A and cell viability and apoptosis were estimated using MTT and propidium iodine/annexin V methods, respectively. Botulinum toxin A exerted greater cytotoxic activity in T47D cells in comparison with MCF10A normal cells; this appeared to be via apoptotic processes caspase-3 and -7. In conclusion, botulinum toxin A induces caspase-3 and -7 dependent apoptotic processes in the T47D breast cancer cell line.

• Coupled systems mechanics
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• 제7권2호
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• pp.163-176
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• 2018

The ship hydrodynamics in static and dynamic states were investigated using 3-dimensional numerical simulations. The static case simulated a fixed ship, while the dynamic case considered a ship with free sinkage and trim using the mesh morphing technique. High speed was found to increase the wave elevation around the ship. Compared with the static case, the dynamic case seemed to generate higher waves near the bow and after the stern. The frictional resistance was found be to more dominant. However, the pressure resistance became gradually important with the increase of the ship speed. The trim and sinkage were also analyzed to characterize the ship hydrodynamics in the dynamic state.

• 전기전자학회논문지
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• 제16권2호
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• pp.153-158
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• 2012

A new diversity combining scheme is proposed for time-of-arrival (TOA) estimation of chirp signal in dense multipath channel. In the multipath channel, the performance of TOA estimation using conventional correlation matrix-based diversity combining scheme is degraded due to the lack of de-correlation effect. To increase the de-correlation effect, the proposed diversity scheme employs interleaving method based on the property of de-chirped signal. As a result, the proposed scheme increases de-correlation effect and also reduces the noise of TOA estimation. Finally, the diversity achieved from the proposed scheme improves TOA estimation performance. The de-correlation effect is analyzed mathematically. The estimation accuracy of the proposed diversity scheme is superior to that of conventional diversity scheme in multipath channel.

• Steel and Composite Structures
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• 제1권2호
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• pp.245-268
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• 2001

The analysis of steel-concrete composite joints presents some particular aspects that increase their complexity when compared to bare steel joints. In particular, the influence of slab reinforcement and column concrete encasement clearly change the moment-rotation response of the joint. Starting from an energy approach developed in the context of steel joints, an extension to composite joints is presented in this paper that is able to provide closed-form analytical solutions. In addition, the possibility of tri-linear or non-linear component behaviour is also incorporated in the model, enabling adequate treatment of the influence of cracked concrete in tension and the softening response of the column web in compression. This methodology is validated through comparison with experimental tests carried out at the University of Coimbra.

• 대한수학회지
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• 제44권2호
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• pp.307-326
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• 2007

We know that there are no real hypersurfaces with parallel Ricci tensor or parallel structure Jacobi operator in a nonflat complex space form (See [4], [6], [10] and [11]). In this paper we investigate real hypersurfaces M in a nonflat complex space form $M_n(c)$ under the condition that ${\nabla}_{\varepsilon}S=0\;and\;{\nabla}_{\varepsilon}R_{\varepsilon}=0,\;where\;S\;and\;R_{\varepsilon}$ respectively denote the Ricci tensor and the structure Jacobi operator of M in $M_n(c)$.

• 이베로아메리카
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• 제22권2호
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• pp.99-122
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• 2020

The design and implementation of the so-called Mexican Fourth Transformation(Cuarta Transformacion, 4T), as an alternative form of government, faces daily the attack and violence of conservatism through a permanent campaign that seeks to instill fear in society, based on a web of lies that tries to create the image of a situation of political ungovernance in the public opinion. This work is a documentary analysis that accounts for the types of harassment of the conservative elite against the 4T; the objective is to show the forms of violence that threaten democracy. In conclusion, this study attempts to argue that the violence that conservative neoliberals caused against the 4T has its origin in that they feel threatened, because the reform policy of AMLO goes against their class interests.