• Title/Summary/Keyword: 자가 이식

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The Developing Trend in Bioresorbable Stent for Treatment of Coronary Artery Disease (관상동맥질환 치료를 위한 생체흡수형스텐트의 개발 동향)

  • Jeong, Gyeong-Won;Kim, Tae-Hoon;Nah, Jae-Woon;Park, Jun-Kyu
    • Applied Chemistry for Engineering
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    • v.29 no.5
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    • pp.497-502
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    • 2018
  • The coronary artery disease (CAD) is rapidly increasing such as angina pectoris and atherosclerosis. The CAD is induce by cholesterol and calcium like plaque absortion to artery wall. The percutaneouss coronary intervention is non-invasive treatment that narrowed-artery is expand by using balloon catheter and bare metallic stent. The metallic stents have been effective in reducing the dead by coronary artery disease, but the permanent presence of the metallic stent has been associated with persistent inflammation, and incidence of late thrombosis. Therefore, development bioresorbable vascular scaffold (BRS) is rapidly increasing for treatment of long-term complications and arterial restenosis by permanentmetal prosthesis such as stent. The review discusses the BRS trend for successfully development.

Obturator Bypass Surgery in a Patient with an Infected Femoral Artery Rupture after Performed ECMO - A case report - (ECMO를 시행했던 환자에서 발생한 대퇴동맥 파열 및 감염의 치료에 있어 폐쇄공 우회술을 시행한 치험 - 1예 보고 -)

  • Bang, Jung-Hee;Woo, Jong-Soo;Choi, Pill-Jo;Cho, Gwang-Jo;Park, Kwon-Jae
    • Journal of Chest Surgery
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    • v.43 no.3
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    • pp.312-315
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    • 2010
  • Infection of both native and prosthetic vessels in the groin is a very serious disease because of recurrent arterial rupture and sepsis, which can cause death. The successful treatment of groin infection, including infection of the femoral artery, requires extensive excision of the infected tissues and restoration of the circulation where the infected area is isolated. Here we describe a case of obturator bypass in a patient with infected femoral artery rupture that occurred after extracorporeal membrane oxygenation for myocarditis and severe heart failure.

Collaborative Network for Children's Reading Program: Making of Bookmagic (전문가 협력을 통한 어린이 독서교육 프로그램 개발 및 운영 - "책수리마수리" 프로젝트의 사례를 중심으로 -)

  • Kim, Eun-Ha
    • Journal of Korean Library and Information Science Society
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    • v.41 no.3
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    • pp.373-389
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    • 2010
  • Bookmagic is a new reading program that encourages children of 5-15 ages to enjoy reading. Bookmagic provides free downloadable resources such as pre-reading and after-reading activities, booklists, posters and awards. Since a number of reading programs have already been developed, published and used, Bookmagic is not a toally new project. However, it is distinguished by the process of creating the program. While most of the reading programs available in Korea were developed by individual occupations(academic experts, private enterprises, civic organisations, associations of librarians or teachers), Bookmagic was designed by a team of various professionals including a picture book author, an academic researcher, a primary school teacher, a school librarian and two public librarians. Working in a partnership with other professionals, participant librarians had a unique opportunity to develop expertises on reading education as a creator of a program rather than as a deliverer.

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Effectiveness of autogenous tooth bone used as a graft material for regeneration of bone in miniature pig (미니피그에서 자가치아뼈 이식의 골형성 효과에 대한 연구)

  • Jeong, Hye-Rin;Hwang, Ju-Hong;Lee, Jeong-Keun
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.37 no.5
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    • pp.375-379
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    • 2011
  • Introduction: This study examined the effect of autogenous tooth bone used as a graft material for bone regeneration in an artificial bony defect of minipigs. Materials and Methods: Four healthy minipigs, weighing approximately 35-40 kg, were used. Four standardized artificial two-walled bony defects, 5 mm in length and depth, were made on the bilateral partial edentulous alveolar ridge on the mandible of minipigs, and autogenous tooth bone was augmented in the right side as the experimental group. On the other hand, only alloplastic bone graft material HA was grafted with the same size and manner in the left side as the control group. All minipigs were sacrificed at 4 weeks after a bone graft and evaluated histologically by Haematoxylin-eosin staining. The specimens were also evaluated semi-quantitatively via a histomorphometric study. The percentage of new bone over the total area was evaluated using digital software for an area calculation. Results: All specimens were available but one in the left side (control group) and two in the right side (experimental group) were missing during specimen preparation. The amount of bone formation and remodeling were higher in all experimental groups than the control. The mean percentage area for new bone in the experimental and control groups was $43.74{\pm}11.96%$ and $30.79{\pm}2.93%$, respectively. Conclusion: Autogenous tooth bone is a good alternative to autogenous bone with the possible clinical feasibility of an autogenous tooth bone graft in the reconstruction of bony defects.

Establishment of Embryonic Stem Cells Derived from Rabbit Embryos (토끼수정란으로부터 배아세포의 분리)

  • 강회성;임경순;최화식;신영수;진동일
    • Korean Journal of Animal Reproduction
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    • v.25 no.3
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    • pp.219-225
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    • 2001
  • To establish rabbit Embryonic Stem (ES) cells, rabbit one-cell embryos were collected and cultured in vitro to blastocysts. Blastocysts were co-cultured with mouse embryonic fibroblasts (MEF), rabbit embryonic fibroblasts (REF) or 570 cells expressing LIF (SNL). Although rabbit ES cells were isolated with low efficiencies, total 8 ES cell lines were kept in vitro with normal colony shape. The MEF was the best feeder for rabbit ES cell isolation in regard to growth rate and undifferentiated morphology. The doubling time of rabbit ES cells in MEF was about 84 hours and the undifferentiated morphology was maintained following passing and freezing processes. These rabbit ES cells were differentiated into embryoid body following the culture in the uncoated dishes, indicating that they were undifferentiated stem cells.

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Root vs. Shoot Genotype Effects on Growth Characters and Seed to Pod-Shell Ratio in Grafted Soybean Plants (콩 유전자형간 상호접목이 지상부 생육과 협실비율에 미치는 영향)

  • Lee, Suk-Ha;Seung, Yeul-Gue;Kim, Yong-Ho;Hong, Eun-Hi
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.39 no.5
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    • pp.458-464
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    • 1994
  • The partitioning of dry matter into seed and pod-shell is important because yield increase can be achieved by improving the distribution rate of assimilation products to seeds. The present study was undertaken to characterize whether the partitioning of dry matter into seed was shoot- or root-controlled through graftiong techniques. Self- and reciprocal-grafts were made among four soybean genotypes, which were 'Baekunkong', 'Suwon 168', and two local soybeans with black seed coat (hereafter referred to as the 'black soybean'), 'Kangleungjarae' and 'Keumleungjarae'. Self-grafted black soybeans showed lower ratio of seed to pod-shell dry wight than self-grafted Baekunkong and Suwon 168. Varying the shoot genotypes in grafts resulted in significant differences in growth characters as well as pod and seed dry weight per plant at physiological maturity. There were significant effects of shoot genotypes on the ratio of seed to pod-shell dry weight, indication that the partitioning of dry matter into seed and pod-shell should be shoot- rather than root-controlled. The grafts with large pod-shell dry weight tended to partition relatively smaller dry matter into seed than pod-shell.

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Simultaneous Aortobifemoral and Bilateral Femoropopliteal Artery Bypass Graft for Multilevel Lower Extremity Occlusive Disease - 2 cases report - (다단계 폐쇄성 하지동맥경화증에서 복부대동맥-양측 대퇴동맥 및 양측 대퇴동맥-슬와동맥간 우회술의 동시 시행 - 2예 보고 -)

  • 박진홍;김응중;지현근;신윤철
    • Journal of Chest Surgery
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    • v.36 no.5
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    • pp.371-374
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    • 2003
  • Atherosclerosis has more than 60% of the causes of arterial occlusive diseases. The abdominal aorta and lower extremity arteries are the most common sites of occlusion. We have treated surgically 2 cases who had intermittent claudication and were diagnosed as simultaneous aortobifemoral and bilateral femoropopliteal obstruction by angiography, but had ineffective results from medical treatment or angioplasty. Simultaneously aortobifemoral bypass using Hemashield Y graft and bilateral femoropopliteal bypass using autologous greater saphenous vein were done. After operations, the symptom disappeared and there were no specific post-operative complications except abdominal wound dehiscence. In postoperative angiography, we had obtained good patency of bypass graft. We are following up patients through the out patient department without recurrence up to 16 months.

Internal Fixation with Plate and Bone Graft of Mid-shaft Clavicle Nonunion (쇄골 간부 불유합의 자가골 이식술 및 금속판 내고정술)

  • Ko Sang-Hun;Cho Sung-Do;Park Moon-Soo;Woo Jong-Ken;Lee Chae-Chil;Jeong Ji-Young;Jung Kwang-Hwan
    • Clinics in Shoulder and Elbow
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    • v.8 no.1
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    • pp.19-22
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    • 2005
  • Purpose: The causes of twelve cases of the mid-shaft clavicle nonunion and the results of internal fixation with plate and bone graft were investigated. Materials and method: From August 1997 to March 2003, twelve cases of the mid-shaft clavicle nonunion were operated with internal fixation with plate and bone graft. The duration of follow-up was average 13 months. Results: The causes of the mid-shaft clavicle nonunion included severe associated injury, severe initial displacement of the fracture fragments and insecure fixation. All cases were operated with internal fixation with plate and bone graft. According to the factor for evaluations of results, using a rating scale of excellent (no apparent factors), good (one factor), fair (two factors), poor (more than three factors), the results showed 10 excellent, 1 good and 1 poor. Screw loosening was developed in only one case . Conclusion: The internal fixation with plate and bone graft of the mid-shaft clavicle nonunion after failed conservative treatment achieved excellent results and seemed to be the procedure of choice for mid-shaft clavicle nonunion.

Study on the characteristics and biodegradable of synthetic PLGA membrane from lactic acid and glycolic acid (젖산 및 글리콜산에서 합성된 PLGA 멤브레인의 특성과 생분해성에 관한 연구)

  • Xie, Yuying;Park, Jong-Soon;Kang, Soon-Kook
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.4
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    • pp.2958-2965
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    • 2015
  • The PLGA(Poly lactide-co-glycolide) Copolymer have been actively applied to the medical implant material as biomaterials. PLGA membrane was able to alveoloplasty with osteotomy for favorable degradation characteristics and possibilities for sustained drug delivery. In this study, PLGA membrane was prepared using phase inversion method, and examined to optical method analysis(NMR, IR), mechanical property measurement (tearing strength) and thermal characteristic analysis(DSC). In addition, the biodegradation characteristics of the PLGA membrane filled with a PBS(Phosphate Buffered Solution) of the water bath ($60^{\circ}C$) according to the degree of surface degradation in the degradation time, the pH change of the solution and change of the mass of the membrane were measured.

COMPARATIVE STUDY OF AUTOGENOUS BONE GRAFT AND GUIDED TISSUE REGENERATION IN THE TREATMENT OF PERIODONTAL DEFECT IN DOGS (성견 치조골 결손부에 자가골이식과 조직유도재생막을 이용한 치주치료시 치유효과에 관한 비교연구)

  • Hong, Ki-Seok;Kim, Jong-Yeo;Chung, Chin-Hyung
    • Journal of Periodontal and Implant Science
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    • v.24 no.1
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    • pp.205-216
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    • 1994
  • The goal of periodontal therapy is the regeneration of the periodontium lost by periodontal disease. The purpose of this study was to evaluate the regenerative potential of the autogenous bone graft and guided tissue regeneration in the treatment of periodontal bony defect in dogs. Experimental periodontitis were induced in the mandibular left 3rd premolar and right 3rd and 4th premolars of 5 dogs using orthodontic ligature wire. After 6 weeks, the ligature wire removed, surgical procedure were performed as follows. 1) control group : Flap operation(Mn.Lt 3rd premolar) 2) experimental group I : Flap operation + autogenous bone graft (Mn.Rt. 3rd premolar) 3) experimental group II : Flap operation + Gore-Tex membrane (Mn.Rt. 4th premoalr) Thereafter, dogs were sacrificed on the 1,2,4,8,16th week and the specimens were prepared and stained with hematoxyline-eosin stain for the light microscopic examination. The results of this study were as follows. 1. The apical migration of junctional epithelium was most remarkable in the flap operation and the experimental group II was less than the experimental group I. 2. In the formation of new alveolar bone, it was found in experimental group I,II and experimental group I is more than II. In the control group, few bone formation was found. 3. In the formation of new cementum, it was found in experimental group I,II and experimental group II is more than I. So, the periodontal therapy combined with autogenous and guided tissue regeneration will be produce the periodontal regeneration.

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