• Title/Summary/Keyword: 염소화 반응

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Hormonal Regulation of the Caprine $\beta$-Lactoglobulin Gene Promoter Activity (염소의 베타-락토글로불린 유전자 프로모터 활성의 호르몬에 의한 조절)

  • 김재만;김경진
    • The Korean Journal of Zoology
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    • v.38 no.3
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    • pp.426-432
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    • 1995
  • Expression of $\beta$-lactoglobulin gene in mammary tissue is strongly induced by lactogenic hormones such as prolactin, glucocorticoid, and insulin. In order to elucidate the regulatory mechanism underlying such hormonal induction, the response of the caprine $\beta$-lactoglobulin gene promoter to lactogenic hormones was analyzed in cultured HC11 mammary cells. Expression with serial deletions of the 5' -regulatory sequence of the $\beta$-lactoglobulin promoter revealed that two regions are responsible for a substantial change in hormonal indudbility. The region upstream of-1692, which exhibited strong repression of the downstream promoter, mediated the induction by insulin. This insulin-response was independent of the other two lactogenic hormones, prolactin and glucocorticoid. The other region from -740 to -470, which showed strong activation of the $\beta$-lactoglobulin promoter in confluent HC11 mammary cells, mediated mainly the response to a glucocorticoid analogue, dexametasone. The induction by the latter region, however, was suppressed by the usptream repression without insulin treatment. These results suggest that the induction of $\beta$-lactoglobulin promoter activity by lactogenic hormones in mammary cells may be achieved by the combined action of derepression by in sulin and activation by glucocorticoid and prolactin. Dexametasone response by the latter region seems to be mediated by the glucocorticoid receptor site around -7OObp.

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Evaluation of Durability of Cement Matrix Replaced with Limestone Powder (석회석 미분말을 혼합한 시멘트 경화체의 내구성능 평가)

  • Woo-Sik Jang;Kwang-Pil Park
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.12 no.1
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    • pp.102-109
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    • 2024
  • In order to use limestone powder as a material for concrete, the mechanical and durability characteristics of cement matrices manufactured by varying the substitution rate were evaluated. In general, limestone powder did not contribute to the cement hydration reaction, so as a result of the compressive strength test of cement mortar using it, the compressive strength decreased as the substitution rate increased. However, as a result of evaluating the durability performance of cement mortar using limestone powder, such as chloride ion penetration resistance, carbonation resistance, and chemical attack resistance, small particles of limestone powder showed superior results compared to the unsubstituted control mortar due to the micro-filler effect of filling the fine pores inside the cement matrix. Therefore, limestone powder is expected to be used as an effective method for improving the durability of concrete. In this study, the durability was evaluated by changing the mixing amount of limestone powder to 0 %, 5 %, 10 %, and 15 %, but it is judged that it is necessary to study in more detail the effect on the durability by changing the end and mixing amount of limestone powder to various levels in the future.

Pentachlorophenol(PCP) Decomposition by the Electron-beam Process (전자빔 공정에 의한 Pentachlorophenol 분해)

  • Kwon, Joongkuen;Kim, Jongoh;Kwon, Bumgun
    • Journal of the Korean GEO-environmental Society
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    • v.13 no.7
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    • pp.49-54
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    • 2012
  • This study focuses on the decomposition of pentachlorophenol(PCP) by an electron beam (E-beam) process. To attain this objective, we investigated the reactive species generated from E-beam process during irradiation (reaction time 0.6 s) and G-values of PCP decomposition and effects of pH and $H_2O_2$ as an additive. The effect of pH values was independent on the decomposition of PCP. However, during E-beam irradiation a scavenging effect of added $H_2O_2$ (> 1mM) for the decomposition of PCP was shown, which was supported by the decreased amounts of $Cl^-$ produced by the decomposition of PCP. Meanwhile, oxalic acid and unidentified organic chlorine compounds as by-products were increased by the addition of $H_2O_2$. Thus, in order to enhance the efficiency of PCP decomposition, the E-beam process has to consider a proper concentration of $H_2O_2$ as a well-known source of strong oxidant hydroxyl radical.

Research on the phenomenon of sick house syndrome and how to remove harmful gases (새집증후군 현상 및 유해가스 제거방안 연구)

  • Choe, Yoowha
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.3
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    • pp.449-456
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    • 2020
  • When you move to a new home, or when you change the wallpaper or flooring of your home, office, etc., you can enjoy the joy of opening your new home with the sick house syndrome, such as the stinging smell and stinging eyes that may appear after the interior work. It is only a moment. Volatile organic compounds from building materials, adhesives, wallpaper, and paints used in new buildings or new furniture cause residents' health and discomfort in indoor life. These volatile organic compounds include benzene, toluene, acetone, and styrene, as well as the representative formaldehyde, and these substances are slowly released over a long period of time, causing acute or chronic diseases to residents. As a method for removing organic volatile substances, physical methods using adsorption, chemical methods for converting volatile substances to other substances, or a mixture of the two are mainly used. In this paper, a sustained release chlorine dioxide gel pack obtained by a method for controlling the reaction rate of a reactant and the release of a product is mixed with a zeolite adsorbent having an optimized hole diameter to adsorb and decompose and remove formaldehyde suspended in the air. I would suggest an effective method.

Durability Evaluation of High-Performance, Low-Heat Self-Compacting Concrete for Foundation of Tall Buildings (초고층 건축물 매트 기초용 고성능 콘크리트 내구성 평가)

  • Kim, Young-Bong;Park, Dong-Cheon
    • Journal of the Korea Institute of Building Construction
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    • v.22 no.5
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    • pp.425-430
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    • 2022
  • Concrete used for the foundation of high-rise buildings is often placed through in an integrated pouring to ensure construction efficiency and quality. However, if concrete is placed integrally, there is a high risk of temperature cracking during the hydration reaction, and it is necessary to determine the optimal mixing design of high-performance, high-durable concrete through the replacement of the admixture. In this study, experiments on salt damage, carbonation, and sulfate were conducted on the specimen manufactured from the optimal high-performance low-heating concrete combination determined in the author's previous study. The resistance of the cement matrix to chlorine ion diffusion coefficient, carbonation coefficient, and sulfate was quantitatively evaluated. In the terms of compression strength, it was measured as 141% compared to the structural design standard of KCI at 91 days. Excellent durability was expressed in carbonation and chlorine ion diffusivity performance evaluation. In particular, the chlorine ion diffusion coefficient, which should be considered the most strictly in the marine environment, was measured at a value of 4.09×E-12m2/y(1.2898×E-10m2/s), and is expected to be used as a material property value in salt damage durability analysis. These results confirmed that the latent hydroponics were due to mixing of the admixture and high resistance was due to the pozzolane reaction.

Electrochemical Oxidation of Glucose at Nanoporous Gold Surfaces Prepared by Anodization in Carboxylic Acid Solutions (카복실산 용액에서 양극산화에 의해 형성된 나노다공성 금 표면상의 전기화학적 글루코오스 산화)

  • Roh, Seongjin;Jeong, Hwakyeung;Lee, Geumseop;Kim, Minju;Kim, Jongwon
    • Journal of the Korean Electrochemical Society
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    • v.16 no.2
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    • pp.74-80
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    • 2013
  • We investigate the formation of nanoporous gold (NPG) surfaces by anodization in three carboxylic acid (formic acid, acetic acid, and propionic acid) solutions and the electrochemical oxidation of glucose at NPG surfaces. Among three carboxylic acids, formic acid provided the most efficient conditions for NPG formation towards glucose oxidation. The optimized conditions during anodization in formic acid for glucose oxidation were 5.0 V of applied potential and 4 hour of reaction time. Electrocatalytic activities for glucose oxidation at NPG surfaces prepared by anodization in carboxylic acids were examined under the absence and presence of chloride ions, which were compared to those observed at NPG prepared in oxalic acid solutions. The application NPG prepared by optimized anodization conditions in formic acid to the amperometric detection of glucose was demonstrated.

Mechanical Properties and Durability of Concrete Incorporating Air-Cooled Slag (서냉슬래그 미분말을 적용한 콘크리트의 역학적 성능 및 내구성 평가)

  • Lee, Seung-Tae;Park, Kwang-Pil
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.3
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    • pp.356-363
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    • 2017
  • Blast furnace slag(BFS) is a by-product generated during the manufacture of pig ion, and is divided into water-cooled slag(WS) and air-cooled slag(AS) by the coking method of BFS. In this study, concrete specimens with ternary binders were produced at the various replacement levels of cement by AS. Various mechanical properties of concrete, such as compressive and split tensile strengths, absorption and water permeable pore, were measured. In addition, the chloride ions penetration resistance and carbonation resistance were tested to evaluate the durability of concrete incorporating AS. The experimental data indicated that the use of AS up to a maximum of 10% replacement level enhanced the concrete performance. However, a higher replacement of AS exhibited poor mechanical properties and concrete durability.

The Rate of Superoxide Radical (${O_2}^-$.) Production in Normal Fenton's Reagent at Different pHs (펜톤반응에서 pH의 변화에 따른 superoxide radical (${O_2}^-$.)의 생성)

  • 김용수;공성호;김재호
    • Journal of Soil and Groundwater Environment
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    • v.7 no.2
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    • pp.73-81
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    • 2002
  • In normal Fenton's reagent, the reductive mechanism of carbon tetrachloride (CT) with superoxide radical (${O_2}^-$.) was observed and the rate of ${O_2}^-$. production was investigated as a function of $H_2O$$_2$ concentration and pH. As pH was increased, the rate of 1-hexanol degradation was rapidly decreased from 90% (at pH 3) to 5% (at pH 11). On the other hand, more degradation of carbon tetrachloride was observed at higher pH regimes indicating Fenton's reaction is an oxidant-reductant co-existing system at neutral pHs. The rate of $O_2^{-}$ . production was observed at different $H_2$$O_2$ concentrations and at different pHs. The rate increased from (45.3$\pm$7.8) x $10^{-6}$ M/s to (151.0$\pm$26.2) x $10^{-6}$ M/s ($294mM H_2$$O_2$) at pH 11: the rate 3150 increased from (22.1$\pm$3.8) x $10^{-6}$ M/s at pH 7 to (151.0$\pm$26.2) x $^10{-6}$ M/s at pH 11 with 294mM $H_2$$O_2$, These results showed that Fenton's reagent could be applied at wide pH regimes. Especially, carbon tetrachloride, which can not be easily adsorbed to soils and then can be dissolved into groundwater causing a cancer, could be efficiently treated by Fenton's reagent.reagent.

Comparison of Different Methods of Aortic Valve Conduit Xenograft Preservation in an Animal Experiment Model; Fresh Cryopreservation versus Acellularized Cryopreservation (동물 실험 모델에서 적용한 이종대동맥판막도관의 조직보존방법 비교; 신선 냉동보존과 무세포화 냉동보존)

  • Kim, Chang Young;Kim, Kyung-Hwan;Moon, Kyung Chul;Kim, Woong-Han;Sung, Si-Chan;Kim, Yong-Jin
    • Journal of Chest Surgery
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    • v.43 no.1
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    • pp.11-19
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    • 2010
  • Background: The commercially used vascular xenografts have some problems such as calcification, fibrosis and tissue degeneration that are associated with inflammatory and immunologic reactions. We compared two methods of xenograft preservation (fresh cryopreservation versus acellularized cryopreservation) of goat aorta. Material and Method: Aortic valved xenografts were harvested from adult pigs, and these were preserved using fresh cryopreservation (FC group, n=4) or acellularized crypreservation (AC group, n=4). These xenografts were implanted into adult goats. There were 2 short-term survivors (less than 100 days) and 2 long-term survivors in each group. These xenografts were explanted and they underwent microscopic examination. Result: The goats survived 31, 40, 107 and 411 days in the FC group and the other goats survived 5, 40, 363 and 636 days in the AC group. All the short-term survivors in each group expired because of rupture at the proximal anastomosis site. Marked neutrophil infiltration was observed in the FC group FC and lymphocytes were observed in the AC group. There were no differences in the occurrence of calcification, fibrosis and thrombosis among the groups. Conclusion: Some goats survived more than 100 days after the xenograft implantation irrespective of the methods of preservation. Because severe tissue degeneration developed in both groups, we think these methods are not appropriate for xenograft preservation of aorta. It was worth a preliminary trial for improving the preservation method or to modify the processing of xenografts.

Catalytic Oxidation of 1.2-Dichloroethane on Precious Metal Catalysts (귀금속 촉매를 이용한 1.2-Dichloroethane의 산화분해에 관한 연구)

  • Lee, Hae-Wan;Kim, Young-Chai;Moon, Sei-Ki
    • Applied Chemistry for Engineering
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    • v.9 no.4
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    • pp.497-503
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    • 1998
  • The catalytic oxidation of 1.2-dichloroethane was investigated over precious metal supported on alumina using a fixed bed microreactor. Among the catalysts tested, the conversion of 1.2-dichloroethane decreased in the following order : Ru > Pt > Pd $${\sim_=}$$ Rh and Pt was found to be the most active catalyst for the complete oxidation of 1.2-dichloroethane to $CO_2$. Major products containing carbon were vinyl chloride and $Co_2$ at temperature ranging from 200 to $400^{\circ}C$. The presence of vinyl chloride in products suggests that the first step in the oxidation of 1.2-dichloroethane is dehydrochlorination and the second is oxidation of vinyl chloride to $CO_2$. To investigate the effect of HCl on the activity of the complete oxidation, some experiments were conducted by adding HCl to the feed. The presence of HCl increased the conversion of 1.2-dichloroethane below $300^{\circ}C$ owing to the increase of surface acidity, but it didn't affect the conversion above $300^{\circ}C$. The reversible adsorption of HCl onto catalyst surface inhibited the complete oxidation to $CO_2$.

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