• Title/Summary/Keyword: 네오디뮴(Neodymium)

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The Effect of Neodymium Oxide on the Generation of Reactive Oxygen Species and DNA Oxidative Damage by Intratracheal Instillation (산화네오디뮴 기도투여에 따른 폐내 활성산소종 발생 및 DNA의 산화적 손상)

  • Kim, Jong-Kyu;Kim, Soo-Jin;Kang, Min-Gu;Song, Se-Wook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.3
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    • pp.336-344
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    • 2014
  • Objectives: This study was performed to assay the effect of neodymium oxide on the generation of reactive oxygen species and DNA oxidative damage by intratracheal instillation. Methods: Two groups of rats were exposed to neodymium oxide($Nd_2O_3$) via intratracheal instillation with doses of 0.5 mg and 2.0 mg, respectively. At two days and at 12 weeks after exposure, the contents of neodymium oxide in the lung, liver, kidney, heart and brain, leukocyte, olive tail moment, ROS, RNS, lactate dehydrogenase, albumin, cytokine and MDA from BALF were measured. Results: Neodymium oxide contents in the liver, kidney, heart, and brain were detected at less than $1{\mu}g/g$ tissue concentration. However, in the lungs at four weeks the highest amount were detected and then found to be drastically reduced at 12 weeks. ROS and RNS in bronchoalveolar lavage increased in concentration dependently at two days, four weeks and 12 weeks after neodymium oxide instillation. However, ROS and RNS decreased with the passage of time. At two days the total number of WBC in BALF in the high concentration group was significantly increased, and at four weeks the total number of WBC were significantly increased in the low and high concentration groups(p<0.01). At two days after exposure, the LDH of the low and high concentration groups was significantly increased. At 12 weeks, only the LDH of the high concentration group was significantly increased compared to in the control group(p<0.01). As a result of Comet assay, after two days, damage to the DNA of the low and high concentration groups was observed. Conclusions: Intratracheal instillation of neodymium oxide induces the generation of ROS and DNA damage in rats.

Performance Evaluation of Microchip Removal Device Rotating by Conveyor Belt with Neodymium Permanent Magnet (네오디뮴 영구자석을 이용한 컨베이어벨트 구동형 미세칩 포집장치의 성능 평가)

  • Choi, Sung-Yun;Wang, Jun-hyeong;Wang, Duck Hyun
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.20 no.1
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    • pp.103-109
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    • 2021
  • Fine chips generated by machining have an impact on machine failure and quality of machined products, it is necessary to remove the chips, so the microchip collection and removal device by rotating conveyor belt with neodymium permanent magnets was developed. In this research, to solve the problem for reducing the existing microchips in the tank, a micro-chip removal device by rotating conveyor belt with neodymium permanent magnets developed. In the development of micro-chip removal device, 3D CATIA modeling was used, and the flow analysis and the electromagnetic force analysis were performed with COMSOL Multiphysics program. To evaluate the performance of the prototypes produced, design of experiments (DOE) is used to obtain the effect of neodymium conveyor movement speed on chip removal for the ANOVA analysis of recovered powders. An experiment was conducted to investigate the effect of the conveyor feed rate on the chip removal performance in detail. As a result of the experiment, it was confirmed that the slower the feeding speed of the fine chip removing device, the more efficient the chip removal.

Pulmonary Toxicity in Rats by Intratracheal Instillation with the Rare-Earth Metal Neodymium Oxide (산화네오디뮴(Nd2O3) 기도투여에 따른 흡입독성)

  • Kim, Jong-Kyu;Kang, Min-Gu;Kim, Soo-Jin;Song, Se-Wook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.3
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    • pp.321-329
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    • 2014
  • Objectives: This study was performed to produce data on the pulmonary toxicity of neodymium oxide($Nd_2O_3$) by intratracheal instillation. Methods: Two groups of rats were exposed to neodymium oxide by intratracheal instillation with doses of 0.5 mg and 2.0 mg, respectively. At two days, four weeks and 12 weeks after exposure, body weight change, organ weight change and histopathological change were observed. At 12 weeks after exposure, lung function change was measured. Results: The body weight of rats in the high concentration group decreased after 12 weeks by 4-5% compared with the control group. At four weeks and 12 weeks after the administration of neodymium oxide, the absolute weight of the lungs of the high concentration group were significantly increased when compared with the control group(p<0.05). At 12 weeks after the injection of neodymium oxide, breath frequency and respiratory minute volume were increased, but inhalation time and expiratory time were decreased. Bronchiolar epithelial hyperplasia, alveolar type II cell hypertrophy/hyperplasia and foreign body granulomatous inflammation were observed in the high exposure group. Conclusions: Body weight decrease, lung absolute weight and breath frequency increase, and pathological lung change were all observed. We found that pulmonary toxicity of neodymium oxide nanoparticles by intratracheal instillation could be confirmed.

Characteristics of Cryolite as an Electrolyte for Reduction of Nd$_2$O$_3$ (네오디뮴 산화물의 전해환원시 전해질로서 빙정석의 특성)

  • 남상욱;백영현
    • Journal of the Korean institute of surface engineering
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    • v.26 no.2
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    • pp.82-86
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    • 1993
  • An attempt was made to reduce directly Nd2O3 in a cryolited based fluoride bath. Neodymium metal was electrodeposited on the iron cathode to produce the Fe-Nd eutectic alloy in a liquid state at 90$0^{\circ}C$. Graphite was adopted for the anode and pure iron for the cathode. Electrolyte was composed of Na3AlF6 50wt.%. AlF3 34wt.% and Nd2O3 16wt.%. Analysis of typical alloy product showed Al 63.4wt.% Fe 26.9wt.% and Nd 7.0 wt.% The enrichment of neodymium in the alloy couldn't be obtained because aluminum codeposited with ne-odydmium. Experimental results proved that the cryolited based electrolyte was unstable for the electrolysis of rare earth oxides even though their prominent solubilities.

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Development of Microchip Removal Equipment Using Neodymium Permanent Magnets (네오디뮴 영구자석을 이용한 미세칩 제거장치의 개발)

  • Choi, Sung-Yun;Wang, Jun-hyeong;Wang, Duck Hyun
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.20 no.3
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    • pp.122-128
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    • 2021
  • Machining operations require removal of chips to keep the coolant clean and fresh throughout the operation time. In this study, microchip removal equipment was developed using AutoCAD and CATIA programs for 3D modeling and 2D draft. In addition, the flow analysis and electromagnetic field analysis of the equipment were performed using the COMSOL Multiphysics program. The flow design of the coolant oil tank was realized on the basis of fluid analysis results. Further, on the basis of magnetic density analysis, a conveyer was designed for effectively removing metal microchips in the tank by using arrays of neodymium permanent magnets.

Iron Removal from Neodymium Chloride Solution with Alamine 336 (Alamine 336을 이용한 염화네오디뮴 수용액으로부터 Fe 제거)

  • Eom, Hyoung-Choon;Lee, Jin Young;Kim, Chul-Joo;Sohn, Jung-Soo;Yoon, Ho-Sung
    • Korean Chemical Engineering Research
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    • v.46 no.3
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    • pp.512-515
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    • 2008
  • The removal of iron from neodymium chloride solution was carried out by solvent extraction using Alamine 336 in kerosine. The effect of Alamine 336, hydrochloric acid and chloride ion concentrations on the extraction of Fe were studied. The results showed that Alamine 336 as an extractant for removal of iron was effective and the extraction percentage of iron was increased with increasing hydrochloric acid and chloride ion concentration in aqueous solution. The extraction of 99% of iron is attained at a ratio of A/O = 4 by distilled water. The stripping yield of iron from loaded Alamine 336 decreased with decreasing hydrochloric acid concentration in stripping solution.

Cytotoxicity and DNA Damage in Human Lung Cells Treated with Lanthanum Oxide and Neodymium Oxide (산화란타늄, 산화네오디뮴이 세포독성 및 DNA손상에 미치는 영향)

  • Kim, Jong Kyu;Kim, Soo Jin;Kang, Min Gu;Chung, Young Hyun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.23 no.2
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    • pp.50-56
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    • 2013
  • Objectives: The present study investigated cytotoxicity and DNA damage in human lung cells in vitro. Methods: Neodymium oxide and lanthanum oxide were dispersed by ultrasonic treatments. The assay was performed with MRC-5 (Human male fetus lung cell). Cytotoxicity and comet assay of lanthanum oxide and neodymium oxide were measured after 24 and 48 hours incubation. Results: After 24 hours of exposure to rare earth metals, the cytotoxicities of lanthanum oxide in more than $1{\mu}M$ concentration groups were significantly increased when compared to the control group, but the cytotoxicities of neodymiun oxide in more than $100{\mu}M$ concentration groups were statistically increased. After 48 hours exposure, cytotoxicities of both materials were statistically increased in $100,000{\mu}M$ concentration groups. Olive tail moments of the lanthanum oxide treated group were significantly increased when compared to the control group. Conclusions: The cytotoxicity of lanthanum oxide was higher than that of neodymium oxide. The DNA of MRC-5 cells treated with lanthanum oxide for 48 hours were significantly damaged.

I-V Characteristics of Praseodymium-Based ZnO Varistors Doped with Neodymium (네오디뮴이 첨가된 프라세오디뮴계 ZnO 바리스터의 I-V 특성)

  • 박춘현;윤한수;남춘우
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 1999.05a
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    • pp.312-316
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    • 1999
  • I-V characteristics of Praseodymium-based ZnO varistor doped with $Nd_2O_3$ in the range 0.0-2.0mol% sintered at 130$0^{\circ}C$ and 135$0^{\circ}C$ were investigated. In the all sides, ZnO varistors sintered at $1300^{\circ}C$ exhibited much better varistor characteristics than that at 135$0^{\circ}C$. All ZnO varistors doped with $Nd_2O_3$ sintered at $1300^{\circ}C$ exhibited good varistor characteristics but particularly ZnO varistor doped with l.Omol% $Nd_2O_3$ exhibited the best characteristics, which the nonlinear is 65.2 and the leakage current is 4.5pA. It is estimated that ZnO varistor doped with l.Omol% $Nd_2O_3$ will begin to be sufficiently used as basic composition to fabricate a good varistor.

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Application of Sedimentary Neodymium Isotopes to the Reconstruction of the Arctic Paleoceanography (퇴적물의 네오디뮴 동위원소 비를 활용한 북극 고환경 복원)

  • Kwangchul Jang;Seung-Il Nam
    • Ocean and Polar Research
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    • v.45 no.2
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    • pp.89-102
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    • 2023
  • Climate and environmental changes in the Arctic Ocean due to global warming have been linked to extreme climate change in mid-latitude regions, including the Korean Peninsula, requiring a better understanding of the Arctic climate system based on the paleo-analog. This review introduces three paleoenvironmental research cases using neodymium isotopes (143Nd/144Nd, εNd) measured on two different fractions of marine sediments: silicate-bound 'detrital' and Fe-Mn oxide-dominated 'authigenic' fractions. In the first case, detrital εNd in core HH17-1085-GC on the continental shelf off northern Svalbard was used for tracing changes in sediment provenance and associated glacier behavior over the last 16.3 ka. The second case showed the potential use of authigenic εNd as a quasi-conservative water mass tracer. Three prominent εNd peaks and troughs observed in core PS72/410-1 from the Mendeleev Ridge in the western Arctic Ocean over the past 76 ka suggested episodic meltwater discharge events during 51~46, 39~35 and 21~13 ka BP. The last case proposed the use of the difference between authigenic and detrital εNd as a proxy for reconstructing glacier fluctuation. The idea is based on the assumption that enhanced glacial erosion during glacier advances can supply sufficient freshly-exposed rock substrate for incongruent weathering, potentially leading to greater isotopic decoupling between bedrock and dissolved weathering products as recorded in detrital and authigenic εNd, respectively. Thus, it would be worthwhile to take advantage of sedimentary εNd to improve our understanding of past environmental changes in polar regions.

A Study on the Characteristics of Material removal using a Round endmill Type MR Polishing System for 3D Shape (3차원 형상 연마를 위한 라운드 엔드밀 타입 MR연마시스템의 재료제거 특성에 관한 연구)

  • Hong, Kwang-Pyo;Shin, Bong-Cheol;Kim, Dong-Woo;Cho, Myeong-Woo;Je, TAe-Jin
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.20 no.5
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    • pp.632-638
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    • 2011
  • Recently, it has been studying for the polishing process of micro parts widely. However, present MR polishing system, it is difficult to minimize electromagnet and to polish sphere or slope parts. Then, it can not be obtained demanded surface quality. In this study, material removal characteristics of BK7 glass using round endmill type MR polishing system were investigated through series of experiment. The experiments were investigated by changing imposed polishing conditions, such as rotational speed and polishing depth. As a results, very high material removal was obtained at 0.7mm gap distance, 1,980rpm.