• Journal of Bio-Environment Control
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• v.17 no.1
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• pp.43-50
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• 2008

This study was conducted to investigate the proper supplied conditions of sodium selenate supplied by fertigation to improve functionality of major western vegetables; beet, broccoli, cabbage lettuce, celery, and parsley in highland. In this work, the growth and content of minerals, ascorbic acid, nitrate, and selenium were measured in western vegetables that treated sodium selenate by different concentration, treatment time and treatment frequency. While there was not different in early growth of some western vegetables among different concentration of sodium selenate; 1,2, 5 and $20\;mg{\cdot}L^{-1}$, at 20 days after treatment, the fresh weight was reduced 33% at cabbage lettuce,47% at broccoli, and 74% at parsley compared control in $5\;mg{\cdot}L^{-1}$ treatment. But the fresh weight of beet and celery reduced just 20% and 15% compared control in even $20\;mg{\cdot}L^{-1}$. The ascorbic acid of cabbage lettuce, celery, and beet increased as sodium selenate concentration increased, so that of cabbage lettuce showed 1.2 times compared control in $20\;mg{\cdot}L^{-1}$ treatment and also that of beet and celery increased 10%. But the ascorbic acid of broccoli and parsley was not influenced by treated sodium selenate. As the concentration of sodium selenate increased, the nitrate contents decreased regardless of crops compared control. This reduced effect of nitrate was highest in cabbage lettuce, followed by beet and celery. The mineral contents, such as K, Ca, and Mg, decreased in all crops, as the concentration of sodium selenate increased. The potassium content showed an obvious negative correlationship with the concentrations of sodium selenate regardless of crops, but the magnesium and calcium content did not show significant difference between treatments. The selenium content increased in proportion as increasing sodium selenate concentrations. The broccoli, celery and parsley treated $20\;mg{\cdot}L^{-1}$ sodium selenate showed 24.4 times, 76.4 times, and 560 times higher than control, respectively. When the sodium selenate supplied to some western vegetables in different growth stage, the selenium content increased 1.3 times and 1.4 times higher in early stage than in late stage in cabbage lettuce and broccoli, respectively. However in parsley and celery, the selenium content showed the highest in middle stage. The selenium content increased in proportion as increasing the sodium selenate treatment frequency, but in above 10 times treatment, the increased effect alleviated in parsley, celery, and cabbage lettuce. On the contrary, the selenium content of broccoli increased constantly as treatment frequency increased.

• Journal of Digital Convergence
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• v.12 no.4
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• pp.419-425
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• 2014

The objective of this study is to estimate the inhibition of skin melanin formation by extract of Angelica koreana and Cnidium monnieri and the possibility of functional cosmetic materials through anti-irritation and stability test. The extract used in this experiment is White-$AK^{TM}$ and the INCI name is Osthole. The main component of White-$AK^{TM}$ was identified as coumarin and EC50 value was 2.7ppm by mouse melanoma B 16 cell test. White-$AK^{TM}$ showed inhibitory effects 100 times lower concentration than arbutin. The main mechanism for skin whitening effect thought to be inhibition of tyrosinase-related gene expression. The basic essence formulation of White-$AK^{TM}$ 5% solution applied to the skin showed the effect of relieving skin irritation. White-$AK^{TM}$ in an opaque container, under UV conditions for 4 weeks, and showed close to 100% recovery and 97% recovery under $50^{\circ}C$ for 4 weeks. Therefore, it is thought that White-$AK^{TM}$ which helps skin whitening, relieving skin irritation and stable in UV condition is able to be used as the functional component in the cosmetic formulation.

• The Journal of the Korea Contents Association
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• v.16 no.3
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• pp.219-231
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• 2016

$^{99m}Tc$-DMSA planar scan that can analyze the functions of kidney quantitatively provides less information on a lesion than tomography scanning. Therefore, this study applied a high sensitivity all-purpose collimator that is sensitive to photonic signals to $^{99m}Tc$-DMSA and carried out a clinical scan with single photon emission computed tomography (SPECT). And diagnostic accuracy and time requirement of were analyzed to know the clinical usefulness of the applied scanning method. 10 subjects were intravenously injected with radiopharmaceutical product (1.0-1.2 MBq/kg) and scanned by a gamma camera with planar scanner (high resolution (HR)-mode, $256{\times}256$, 50 kcts/view, 4 image) and SPECT (HR / high sensitive (HS)-mode, $128{\times}128$, step and shoot, $180^{\circ}$, variable sec/angle, total 64 frame, OSEM reconstruction), respectively. The collected data was compared with an analysis program. The results showed that HS-mode SPECT detected total counts 1.8-5.6 times more than planar scan. Relative renal function evaluated based on the counts was not significantly different by two scanning methods (p=0.96) and it turned out that test time was shortened by 39% when HS-mode SPECT was used. Therefore, SPECT using HR, HS-mode collimator could analyze renal function more quantitatively than using planar scan and the former could diagnose the location information of a lesion more accurately than the latter as well as shortened test time requirement, which demonstrated the clinical usefulness of $^{99m}Tc$-DMSA renal SPECT using high sensitivity all purpose collimator.

• Journal of Life Science
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• v.21 no.4
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• pp.596-603
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• 2011

This study was conducted to investigate traditional medicinal plants (TMP) 1 and 2, two different multi-herbal mixtures consisting of 24 herbs. Regarding the contents of flavonoid compounds, the ethanol extract (EE) of TMP2 yielded the highest content of flavonoid compounds (40.981 mg/g), followed by EE of TMP1 (28.23 mg/g), hot water extract of TMP2 (WE, 10.046 mg/g), and WE of TMP1 (6.59 mg/g). Antioxidant activities of EE and WE of TMP1 and TMP2 were measured based on DPPH radical scavenging activity. At 1 mg/ml, the highest DPPH radical scavenging activity was shown in EE of TMP2 (96%), followed by EE of TMP1 (94%). Nitric oxide (NO) production by RAW264.7 macrophage cells stimulated with lipopolysaccharide (LPS) was reduced to 82, 77, 86, and 47% by addition of $500\;{\mu}g/ml$ of EE and WE of TMP1 and TMP2, respectively. These results were not due to the cytotoxicity of the extracts. NO synthesis was increased by 2.3, 3.6, 3.0, and 1.8 fold by addition of $500\;{\mu}g/ml$ of EE and WE of TMP1 and TMP2, respectively. These results show that medicinal plants play a significant role in antioxidative activity and activation of the immune system in the pathogenesis of inflammatory diseases, and different mixtures of the medicinal plants showed different effects.

• Korean journal of applied entomology
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• v.61 no.4
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• pp.669-673
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• 2022

To evaluate biological activity of honeydew honey produced by Apis mellifera L. in Korea, we measured antioxidant activity by using DPPH (1,1-diphenyl-2-picryl hydrazyl), ABTS [2,2-azobis(3-ethylbenzothiazoline-6-sulfonate)], FRAP (Ferric reducing antioxidant power), and total polyphenol content assays. Korean honeydew honey respectively scavenged 26% and 86% of DPPH and ABTS radicals at the highest concentration of 10 mg/mL. In the result of FRAP assay, Korean honeydew honey showed activity (126 µM of FRAP value) to reduce Fe³⁺ to Fe²⁺. Total polyphenol content was 73.41 mg GAE/kg. Korean honeydew honey exhibited excellent antioxidant activity due to having high radicals scavenging ability and reducing power of ferric ion as well as the presence of phenolic compounds. These findings suggest that Korean honeydew honey has great potential as a functional food material.

• Korean Journal of Food Science and Technology
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• v.54 no.1
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• pp.94-102
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• 2022

Defatted soybean, larvae of brown mealworm (Tenebrio molitor), and powdered pupae of silkworm (Bombyx mori) were fermented in solid and liquid forms using Aspergillus oryzae and Bacillus subtilis. The protein degradation rate (NDR) through solid fermentation was the highest in the fermented soybean control sample (54.69±6.54%), followed by silkworm pupae (34.82±5.99%) and brown mealworm larvae (30.54±3.80%). When these edible insects were fermented in liquid form, solid extraction yield was 37.73-46.88%, and protein yield was 47.47-63.02%. NDR of fermented liquid form products increased to 58.90, 52.62, and 50.13% for soybean, brown mealworm larvae, and silkworm pupae, respectively. SDS-PAGE of the liquid fermented products confirmed that microbial fermentation decomposed higher-molecular-weight proteins into small polypeptides. In vitro digestibility of liquid forms of edible insects increased by 1.26 to 1.53 times after fermentation. The protein solubility, foaming ability, and foam stability of liquid-fermented edible insects all tended to increase through fermentation.

• Applied Chemistry for Engineering
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• v.35 no.4
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• pp.335-340
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• 2024

In this paper, we synthesized organic and inorganic hybrid materials to introduce antibody functionality to UIO-66 and incorporated them into a surface plasmon resonance (SPR) assay to enhance the sensitivity of detecting small molecules such as oxytocin. A biological marker peptide called oxytocin may help in the diagnosis of heart failure, Alzheimer's disease, and cancer. To detect oxytocin at concentrations as low as a few femtomole (fM), we developed a surface sandwich assay utilizing a pair of oxytocin-specific antibodies for enhancing selectivity and one of metal organic frameworks [e.g., UiO-66-(COOH)₂] possessing high porosity and surface-area as a signal amplifier. Initially, real-time SPR assays were used to confirm that each selected oxytocin-specific antibody binds strongly to oxytocin and to different binding sites on oxytocin. One of these antibodies (e.g., anti-OXT[OTI5G4]) was immobilized on the surface of a thin gold chip. Upon sequential injecting of oxytocin and the other antibody (e.g., anti-OXT[4G11]) conjugated to UiO-66-(COOH)₂ onto the surface to form the surface sandwich complex of anti-OXT[OTI5G4]/oxytocin/UiO-66-(COOH)₂-anti-OXT[4G11]), SPR changes, which varied with oxytocin concentration, were then measured in real time. The results demonstrated that sensitivity was amplified by over a million-fold compared to assays without UiO-66-(COOH)₂, enabling oxytocin detection down to approximately 10 fM.

• Journal of the Korean Society of Clothing and Textiles
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• v.27 no.12
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• pp.1441-1452
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• 2003

오늘날 지체장애인의 수는 후천적 원인으로 인하여 점점 증가하는 추세에 있다. 이에 본 연구는 훨체어를 사용하는 하반신마비자 중 성인남성을 중심으로 인체계측을 통해 적합성이 높은 바지를 개발하는데 목적이 있다. 연구 결과는 다음과 같다. 1. 인체계측 결과 하반신마비자들은 정상인과 비교했을 때 허리둘레 및 배둘레에서 유의한 차이를 보여 새로운 치수체계가 필요로 함을 알 수 있었다 또 자세 변화에 따른 둘레항목의 치수 변화와 피부 신축율에 의해 허리선의 변화가 고려되어 평상시의 휠체어에 앉은 자세에서 계측한 항목으로 원형이 설계되어야 할 필요가 있다고 분석되었다. 2. 연구원형은 기성복화 하기 위한 방법으로 먼저 기준치수(98-102)를 선정하고, 원형 각 부위는 절대치로 수치화 시켜서 제시하였다. 뒤밑위길이선은 허리선에서 8cm 늘이고 앞밑위길이선은 허리선에서 6cm 줄여 앉은 자세에서 편안함을 확보할 수 있도록 하였다. 기준치수의 경우 바지길이 107cm, 밑위길이 26cm, 밑위선 28cm, 엉덩이둘레선은 밑위선 위로 8.5cm, 바지부리는 10.5cm이고 외관과 기능성 평가 결과 대부분의 항목에서 우수한 평가를 받았다. 3. 계측 대상자 계측치를 근거로 치수의 출현율을 고려하여 연구 치수체계를 기본 신체부위인 앉은 허리둘레와 앉은 엉덩이둘레의 순으로 적용하여 총 7개의 치수로 설정하였다. 기준치수(98-102)의 연구원형을 마스터 패턴으로 하고 구체적인 원형 부위별 절대치로써 치수 차를 검토하여 연구 그레이딩 룰을 설계하였으며 기준치수 보다 작은 사이즈 88-93과 큰 사이즈 108-111의 적합성을 검증하였다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.12
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• pp.1816-1822
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• 2016

This study investigated the quality characteristics and antioxidant activities of madeleine added with lentil powder (LP). Madeleine was prepared with flour levels of lentil powder (0, 20, 40, and 60%). The pH, moisture, and specific gravity of madeleine decreased with increasing amounts of LP, whereas loss rate increased. Hunter L and b values of crust decreased with increasing amounts of LP, whereas a value of crust increased (P<0.05). Hunter L and b values of crumb increased with increasing amounts of LP, whereas a value of crumb decreased (P<0.05). For texture of madeleine with increasing amounts of LP, hardness and adhesiveness increased, whereas springiness, cohesiveness, and chewiness were reduced. DPPH radical scavenging activity of LP madeleine significantly increased with increasing amounts of LP (P<0.05). In the sensory evaluation of appearance, color, flavor, texture, taste, and overall preference, madeleine with LP 20% showed the highest value. It is suggested that LP 20% madeleine could be substituted for wheat flour to improve madeleine quality.

• Korean journal of food and cookery science
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• v.23 no.4 s.100
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• pp.561-566
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• 2007

Fish paste containing anchovy (FPA) was prepared, and its quality was evaluated by determining calcium content, color, textural properties, and sensory attributes. The calcium content of FPA increased with an increasing amount of anchovy powder. The anchovy powder in the FPA tended to decrease lightness (L), and redness (a), but increased yellowness (b) for the Hunter color values. All test samples of 3 mm thickness had good flexibility, and did not break even after a 4-fold increase in applied stress. The FPA containing 20% anchovy showed the highest values in strength, hardness, and adhesiveness. For overall acceptance in the sensory evaluation, the FPA containing 5% anchovy was not different than the non-added control. These results suggest that anchovy can be applied to fish paste products for the purpose of high quality and functionality.