• 한방안이비인후피부과학회지
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• 제28권4호
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• pp.208-214
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• 2015

Objectives : The purpose of this study is to present two case reports on the treatments of psoriasis who has functional gastrointestinal disorder.Methods : We administered herbal medicine to two patients who showed psoriasis with functional gastrointestinal disorder and evaluated the results by Psoriasis Area and Severity Index(PASI).Results : After the treatment two patients showed improvements in PASI. PASI of patient 1 changed from 8.8 to 0.8; patient 2 from 7.0 to 0.2Conclusions : The results suggest that herbal medicine can be an effective treatment for psoriasis who has functional gastrointestinal disorder.

• 한방안이비인후피부과학회지
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• 제30권4호
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• pp.167-175
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• 2017

Objectives : The purpose of this study is to present 3 cases reports of psoriasis treated by Damwi-hwan - focused on lipid metabolic abnomarilty. Methods : We administered Damwi-hwan to three patients who showed psoriasis with lipid metabolic abnormality and evaluated the results by Psoriasis Area and Severity Index(PASI). Results : After the treatment three patients showed improvements in PASI. PASI of patient 1 changed from 15.4 to 0.4; patient 2 from 32.7 to 1.2 ; patient 3 from 7.6 to 0.6. Conclusions : The results suggest that Damwi-hwan can be an effective treatment for psoriasis who has lipid metabolic abnormality.

• 한방안이비인후피부과학회지
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• 제32권4호
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• pp.141-150
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• 2019

Objectives : The purpose of this study is to report the effect of Korean Medicine on erythrodermic psoriasis. Methods : We administered herbal medicine to three patients who showed psoriasis. There were no other treatment except herbal medicine. And we evaluated the results by Psoriasis Area and Severity Index(PASI). Results : After the treatment three patients showed improvements in PASI. PASI of patient 1 changed from 26.2 to 0.3 after 149 days; patient 2 from 40.5 to 5.8 after 106 days; patient 3 from 31.6 to 0 after 294 days. Conclusions : The results suggest that herbal medicine can be an effective treatment for erythrodermic psoriasis patients.

• 한방안이비인후피부과학회지
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• 제25권4호
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• pp.35-44
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• 2012

Objectives : This study was aimed to evaluate the treatment effect of psoriasis patient using pyretotherapy. Methods : The clinical study was performed using retrospective observational research method. Treatment method was pyretotherapy that optimized core temperature through herbs therapy, food therapy, excercise and life style change. In other aspects, pyretotherapy is skin cure therapy that rise core temperature, down skin temperature and open sweat gland. Results : 1. 40s years showed the most coming of clinic in the distribution of age of psoriasis patient. 2. Board type showed the most number in the classification of psoriasis. 3. Pyretotherapy was very effective results in psoriasis patient treatment. 4. Pyretotherapy showed effects of rising axillary temperature and moving facial high skin temperature toward abdominal portion. Conclusions : The author is able to say that it is possible for pyretotherapy to become new skin therapy for many skin disease, especially psoriasis.

• 한방안이비인후피부과학회지
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• 제31권1호
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• pp.91-105
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• 2018

Objectives : The purpose of this study is to report the Sik-yang-seng(食養生) therapy with Korean Medicine and acupuncture on a chronic psoriasis patient who is occurred to latrogenic cushing's syndrome. Methods : The patient who has been diagnosed psoriasis had symptoms with latrogenic Cushing's syndrome. The patient was treated with Sik-yang-seng(食養生) therapy including Korean Medicine and acupuncture. Evaluation was done by PASI score, itching score, statistics and pictures. Results : After treatment, the PASI score of patients with Sik-yang-seng(食養生) therapy including Korean Medicine and acupuncture was 1.8 which means 95.5% improvement. Conclusions : Korean medical treatment performed with Sik-yang-seng(食養生) therapy can help recovery of Biwi(脾胃)function therefore can increase effect of the treatment of psoriasis and latrogenic Cushing's syndrome.

• 한국컴퓨터정보학회:학술대회논문집
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• 한국컴퓨터정보학회 2020년도 제61차 동계학술대회논문집 28권1호
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• pp.33-34
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• 2020

사용자의 피부 관리 및 피부질환을 검사하는 기존의 어플리케이션은 유도 질문에 따른 사용자의 응답을 기반으로 결과를 유추하기 때문에 부정확한 진단 결과를 야기한다. 본 논문에서는 사용자의 미용관련 피부질환 이미지를 바탕으로 딥러닝 이미지 인식 기술 적용하여 건선, 사마귀, 여드름, 한포진을 대상으로 피부 미용질환에 대한 식별 정보를 제공하는 어플리케이션을 제시한다. 또한 이미지 인식률이 높은 ResNet과 SE-ResNet 알고리즘을 적용하여 피부질환 식별 적용 시 효과성을 실험적으로 비교한다.

• 한방안이비인후피부과학회지
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• 제29권2호
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• pp.12-32
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• 2016

Objectives : The objective of this study is to develop the strategies of the psoriasis clinical trials guideline on Korean medicine by comparison between Clinical guidelines and domestic and foreign clinical trials papers of psoriasis on Korean medicine. Methods : This study is based on analysis of papers on Clinical trials guidelines, Clinical practice guideline and clinical trials about Korean medicine. The papers were searched from Pubmed, Medline, Oasis(Oriental Medicine Advanced Searching Integrated System), Korean Traditional Knowledge Portal and Google portal database. Results : A total 8 Clinical practice guidelines and 2 Clinical trials guidelines were found. Moreover, there were 15 foreign papers about clinical trials and 29 internal articles about case studies. They suggested the diagnostic strategy, classification, effective outcome measure, severity measure, precaution of combination therapy, precaution and treatment period of clinical trials, safety evaluation, patterns of Korean Medicine, clinical specific features on psoriasis.Conclusions : The criteria of every item to provide the clinical trials guideline using Korean medicine on psoriasis were developed by apply the results. If we accumulate the more clinical articles on Korean medicine, it will be great help to develop the reliable standard of that guideline.

• 사상체질의학회지
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• 제15권2호
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• pp.94-100
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• 2003

The purpose of this study is to give an account of the effects of the Korean herbal medicine therapy which is based on the Sasang constitutional medicine for the patient who has suffered from scale of both foot caused by chronic psoriasis. The subject is a 81-year old man who has the symptoms caused by lacunar infarction, which are both leg weakness, gait disturbance, dizziness, dysarthria, frequency voiding, and scale of both foot caused by chronic psoriasis. We have diagnosed him as Shaoyangin(少陽人), and have prescribed Yukmi jiwhangtang(六味地黃湯). The consequence is the accompanied scale of both foot, both leg weakness, gait disturbance, dizziness, frequency voiding and general condition has improved.

• 동의생리병리학회지
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• 제17권6호
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• pp.1543-1546
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• 2003

Psoriasis is a common inflammatory disease of the skin marked by excessive scaling associated with inflammation, affecting 1-2% of the population. Although their etiologies remain unknown, the finding of CD4+ and CD8+ lymphocytes at sites of psoriasis has led many reports to hypothesize that psoriasis is a T lymphocyte-mediated disease directed against unknown autoantigens. The oriental medicine understands the cause of psoriasis as low humidity of skin tissues and functional deteriorations of the liver and lung. Gami-Yunbueum (GY) is a mixture of two previous prescription, which were used to the protection of liver and lung. We had prescribed the GY to the three psoriasis patients for 11 weeks and examined the effectiveness of the GY by PASI (Psoriasis Area and Severity Index) score. In our experiment, GY improved the symptoms of psoriasis in all cases. These results indicated that GY can apply to the treatment of psoriasis. Furthermore, the process for treatment of psoriasis is possible to provide humidity to skin and control the functions of liver and lung.

• 한국임상약학회지
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• 제13권2호
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• pp.97-105
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• 2003

아스코마이신(ascomycin)의 macrolactam 유도체인 피메크로리무스(pimecrolimus; 엘리델 [Elidel], SDZ ASM 981; Novartis Pharma AG, 바젤, 스위스)는 세포선택성을 지닌 염증성 사이토카인(cytokines) 억제제로서 아토피피부염, 알레르기성 접촉피부염, 자극성 접촉피부염 및 판형 건선 등 염증성 피부질환의 치료제로 개발되었다. T세포와 비만세포의 염증성 사이토카인 생산 분비를 억제하고 사전 형성된 염증성 매개물질의 비만 세포 분비를 저해한다. 국소 투여된 피메크로리무스는 알레르기성 접촉피부염(allergic contact dermatitis [ACD]) 돼지 모델에서 고역가 코르티코스테로이드 클로베타졸-17-propionate(corticosteroid clobetasol-17-propionate)와 동등한 효과를 나타낸다. 하지만 피메크로리무스는 클로베타졸과는 달리 피부 위축을 일으키지 않는다. 경구 투여시 피메크로리무스는 마우스와 랫트 ACD 치료에 있어서 타크로림무스(tacrolimus [FK 506])와 동등한 혹은 더 우수한 효과를 나타낸다. 또한 피메크로리무스는 아토피피부염 급성 징후 유사 모델인 저마그네슘 혈증 탈모 랫트(hypomagnesemic hairless rat)의 피부 염증과 소양증을 효과적으로 감소시킨다. 피메크로리무스는 랫트에서 다음과 같은 측면의 전신 면역반응 손상 효과가 타크로리무스 와 비교하여 낮게 평가된다: (1)국소 이식편대 숙주 반응, (2)양(sheep) 적혈구에 대한 항체 형성, (3)신장이식. 시험관내 평가시 돼지 피부를 통한 피메크로리무스 투과 속도가 타크로리무스보다 10배 낮게 측정되므로 생체에서 경피 흡수가 더 적게 될 것으로 판단된다. 상기 자료로 판단컨대 피메크로 리무스는 피부에 대한 항염증 활성이 높을 뿐 아니라 전신 면역반응 손상 부작용이 낮은것으로 사료된다.