• Title/Summary/Keyword: (ESI)

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UHPLC-ESI-qTOF-MS Analysis of Cyclopeptide Alkaloids in the Seeds of Ziziphus jujuba var. spinosa

  • Kang, Kyo Bin;Jang, Dae Sik;Kim, Jinwoong;Sung, Sang Hyun
    • Mass Spectrometry Letters
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    • v.7 no.2
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    • pp.45-49
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    • 2016
  • An UHPLC-ESI-qTOF-MS analytical method was developed for cyclopeptide alkaloids in the seeds of Ziziphus jujuba var. spinosa (Semen Ziziphi Spinosae), which is a commonly used herb in Chinese and Korean traditional medicines. Considering the basicity of cyclopeptide alkaloids, a specific separation method was developed for an UHPLC system. The compounds were detected by DAD and ESI-qTOF-MS, and their fragmentation patterns were also acquired by MSE technologies. Peak-picking of major compounds was performed with nine previously isolated compounds and two reference standard compounds. Tandem MS fragmentation behaviors of type-Ia and -Ib cyclopeptide alkaloids were investigated with the acquired data to develop a strategy for dereplication of other cyclopeptide alkaloid compounds in Z. jujuba var. spinosa. Two more cyclopeptide alkaloids were tentatively identified with UHPLC-ESI-qTOF-MS using this method.

Application and Development of Integration Technique to Generate Land-cover and Soil Moisture Map Using High Resolution Optical and SAR images

  • Kim Ji-Eun;Park Sang-Eun;Kim Duk-jin;Kim Jun-su;Moon Wooil M.
    • Proceedings of the KSRS Conference
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    • 2005.10a
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    • pp.497-500
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    • 2005
  • Research and development of remote sensing technique is necessary so that more accurate and extensive information may be obtained. To achieve this goal, the synthesized technique which integrates the high resolution optic and SAR image, and topographical information was examined to investigate the quantitative/qualitative characteristics of the Earth's surface environment. For this purpose, high-precision DEMs of Jeju-Island was generated and data fusion algorithm was developed in order to integrate the multi-spectral optic and polarimetric SAR image. Three dimensional land-cover and two dimensional soil moisture maps were generated conclusively so as to investigate the Earth's surface environments and extract the geophysical parameters.

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Sunroof Buffeting Simulation of a Simplified Car Model using PAM-FLOW (PAM-FLOW를 이용한 단순차량 모델의 썬루프 버페팅 소음 해석)

  • Lee, Dong-Guk;Park, Il-Kyoo;Lim, Jong-Yun
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.24 no.3
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    • pp.198-204
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    • 2014
  • This paper presents a benchmark test result of an application of computational fluid dynamics(CFD) analysis of automotive sunroof buffeting simulation. Computational analyses of flow over an open sunroof of a simple vehicle model called as HAWT(Hyundai aeroacoustic wind tunnel) model were performed to study the buffeting phenomenon and to predict the buffeting noise level and its frequency. Computations are performed for sunroofs with PAM-FLOW software which is one of powerful CFD code of ESI group. Numerical predictions are compared with result from the tunnel test measurements. It is shown that CFD analysis has great potential for sunroof design and development by predicting buffeting noise.

The Effects of Catheter Revision and Mupirocin on Exit Site Infection/Peritonitis in CAPD Patients (복막 투석 환자에서 도관 관련 감염 및 복막염에 대한 Mupirocin과 도관 전환술(Catheter revision)의 효과)

  • Park, Jun-Beom;Kim, Jung-Mee;Choi, Jun-Hyuk;Jo, Kyu-Hyang;Jung, Hang-Jae;Kim, Yeung-Jin;Do, Jun-Yeung;Yoon, Kyung-Woo
    • Journal of Yeungnam Medical Science
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    • v.16 no.2
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    • pp.347-356
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    • 1999
  • Background: Exit site/tunnel infection causes considerable morbidity and technique failure in CAPD patients. We presently use a unique revision method for the treatment of refractory ESI/TI in CAPD patients and mupirocin prophylaxis for high risk patients. Materials and Methods: We reviewed 139 CAPD patients about the ESI/TI from October 1993 to February 1999 at Yeungnam University Hospital. At the beginning of the ESI. we usually started medications with rifampicin and ciprofloxacin and then changed the antibiotics according to the sensitivity test. If the ESI had persisted and there were TI symptoms (purulent discharge, abscess lesion around exit site). we performed catheter revision(external cuff shaving, disinfection around tunnel and new exit site on opposit direction) with a combination of proper antibiotics. We applied local mupirocin ointment at the exit site three times per week to the 34 patients who had the risk of ESI starting from October 1998. Results: The total follow-up was 2401 patient months(pt. mon). ESI occurred on 105 occasions in 36 out of 139 patients, and peritonitis occurred on 112 occasions in 67 out of 139 patients. The total number of incidences of ESI and peritonitis was 1 per 23.0 pt. mon and 1 per 2l.6 pt.mon. The most common organism responsible for ESI was Staphylococcus aureus (26 of 54 isolated cases, 48%), followed by the Methicillin resistant S. aureus(MRSA) (13 cases, 24%). Seven patients(5: MRSA. 2: Pseudomonas) had to be treated with a revision to control infection. Three patients experienced ESI relapse after revision. One of them improved with antibiotics, while another needed a second revision and the remaining required catheter removal due to persistent MRSA infection with re-insertion at the same time. But, there was no more ESI in these 3 patients who were received management to relapse (The mean duration: 14.0 months). The rates of ESI were significantly reduced after using mupirocin than before(1 per 12.7 vs 34.0 pt.mon, P<0.01). Conclusions: In summary, revision technique can be regarded as an effective method for refractory ESI/TI before catheter removal. Also local mupirocin ointment can play a significant role in the prevention of ESI.

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Environmental Monitoring after Nakhodka Oil Spill and Utilization of GIS/GPS and Hi-resolution Satellite Images

  • Sawano, Nobuhiro
    • Proceedings of the KSRS Conference
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    • 2002.10a
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    • pp.627-632
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    • 2002
  • One main purpose of environmental monitoring after oil spill is developing ESI (Environmental Sensitivity) Maps. Environmental impacts caused by the spilt oil are strongly depending upon the coastal topology and geology. Monitoring all impacted shorelines is almost impossible; using high-resolution satellite images such as IKONOS greatly contributes to improve the efficiency of on-site researches, at the same time, reliability of ESI maps.

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경제체감(Economic Sentiment)의 측정

  • Min, Gyeong-Sam;Jang, Seon-Hui
    • Proceedings of the Korean Statistical Society Conference
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    • 2005.05a
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    • pp.121-128
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    • 2005
  • 경기를 보다 정확하게 예측하고 대응하기 위해서는 실물경기지표뿐만 아니라 기업과 소비자의 주관적이고 심리적인 판단 즉 경제체감을 파악하여 분석할 필요가 있다. 따라서 이 연구에서는 기업경기 및 소비자 전망조사의 통계자료들을 활용하여 경제체감(Economic Sentiment) 측정을 시도하였으며, EU 접근방식을 적용하여 2003년 1월부터 2005년 3월까지 우리나라의 경제체감지수(ESI)를 작성하였다. 작성한 지수의 상관분석 결과는 경제체감지수(ESI)가 양호한 선행지표로서 기능할 수 있음을 시사하고 있다.

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Generation of High Resolution DEM of Jeju Island

  • Lee, Chang-Won;Kim, Duk-Jin;Moon, Wooil M.
    • Proceedings of the KSRS Conference
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    • 2003.11a
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    • pp.831-833
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    • 2003
  • We have evaluated the accuracy of digital elevation models of Jeju island generated with three different sensors, NASA JPL TOPSAR, JERS-1 SAR, KOMPSAT-1 EOC using Interferometric SAR and stereo photogrammetry. Characteristics and limitations of each method are described.

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31P NMR and ESI-MS Study of Fenitrothion-Copper Ion Complex: Experimental and Theoretical Study

  • Choi, Ho-June;Yang, Ki-Yull;Park, Jong-Keun;Koo, In-Sun
    • Bulletin of the Korean Chemical Society
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    • v.31 no.5
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    • pp.1339-1342
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    • 2010
  • $^{31}P$ NMR and ESI-MS studies of $Cu^{2+}$ binding to Fenitrothion (FN) were performed by experimentally and theoretically. The calculated $^{31}P$ NMR chemical shifts for FN-$Cu^{2+}$ complexes are in good agreement with experimental chemical shifts in order, and the results present an important information for organophosphorus pesticide metal complexes. ESI-MS and low energy CID MS/MS experiments of FN-$Cu^{2+}$ complexes combined with accurate mass measurements give insight into the metal localization and allow unambiguous identification of fragments and hydrolysis products.