• Herbal Formula Science
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• v.12 no.2
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• pp.139-154
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• 2004

Acetaminophen은 세계적으로 널리 사용되는 해열 진통제이지만, 또한 과용 및 남용, 알코올 중독과 같은 여러 원인에 의해 간독성을 유발할 수 있는 약물이다. 이러한 acetaminophen의 간독성은 CYP에 의해 생성되는 대사산물인 NAPQI와 활성산소에 의해 유발되는 것으로 알려져 있다. 본 연구에서 5주된 수컷 백서에 acetaminophen (500 mg/kg)을 투여하기 전에 대시호탕 (500 mg/kg)를 일주일간 투여하였다. 이후 GOT, GPT, GST 그리고, 조직사진으로 대시호탕의 간보호작용을 측정하였다. 또한 대시호탕의 간보호작용 기전을 항산화작용과 CYP 2E1 발현조절을 통한 NAPQI 생성억제의 두 가지 면에서 측정하였다. GOT, GPT 그리고 조직사진에서 나타난 결과들은 대시호탕이 고용량의 acetaminophen에 대한 간보호작용이 있음을 증명할 수 있었다. 또한 LPO와 catalase, 그리고 GSH 실험에서 나타난 결과들을 통해 대시호탕이 항산화작용이 있음을 알 수 있었다. 그리고 GSH, GST, RT-PCR, western blot 실험에서 대시호탕이 CYP 2E1의 발현을 조절하여 NAPQI 생성을 억제한다는 것도 알 수 있었다. 이상의 결과들을 바탕으로 대시호탕은 항산화작용에 의한 활성산소 제거력과 CYP 2E1의 발현조절을 통한 NAPQI 생성억제로 고용량 acetaminophen에 의해 유도된 간손상에 대해 유의성 있는 보호작용을 한다는 것을 알 수 있었다.

• The Journal of the Korea Contents Association
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• v.8 no.7
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• pp.233-242
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• 2008

Sales-force management practices(e.g., selection, training, rewards, evaluation) constitute a crucial aspect of the sales force control system, as they influence on the salesperson's role ambiguity, satisfaction and performance. But it is difficult to find studies on the effects of hotel's sales force control system. So, we studied about this subject more deeply. The purpose of our research is to examine important relationships among sales force control system(e.g., sales territory design, training, reward, training, supervisor's support), job attitudes(satisfaction and role ambiguity), and sales force performance. A conceptual model is presented and hypotheses are developed. This study contributes to sales management research of hotel sales person in some important ways. This study offers new insights both to sales practitioners and researchers. First, this study introduces a new approaching method for developing new model of hotel sales-force research. Second, in the practical implications, managers should take actions as like an encouragement, direction, monitering, and education of sales know-how to reduce the employee's role ambiguity and to improve job satisfaction and sales performance.

• Archives of design research
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• v.18 no.2 s.60
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• pp.5-14
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• 2005

Graphic Design is being developed as a unique genre and widely applied to movie, TV broadcasting, music video, computer an, web design, animation, and game. Some university added motion graphics in their curriculum recently. However Motion Graphic has not been defined clearly and pedagogy of motion graphics was not studied enough. Motion Graphic is not merely moving picture. Its typical purpose and concept are evolving because of the diversified application. Meta-synthesis between media and hybrid development based on diverse approach and composite presentational methods are also changing Motion Graphic. Various technology such as photograph, analytical engine, hypermedia, multimedia, digital composite picture, network and interface should be studied to understand Motion Graphic. This study reviews the historic background of Motion Graphic mainly related to its advent. A fundamental definition of Motion Graphic including the space and time is suggested and the international trend is introduced. Future Motion Graphic and possible development was also predicted.

• The Journal of the Korea Contents Association
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• v.12 no.4
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• pp.108-118
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• 2012

In Korean society entered into an aging society, seeing aging women's lives, the lives of older women through women's eyes means, in a sense, calling the older female audience as the subject. On International Women's Film Festival in Seoul (2006), and now in South Korea opened with the title (2002) through the respective movies understanding 'aging' and the way represented older women will be discussed. shows grandma Marta's a pleasant commotion drew with the villagers, family and friends until openig Lingerie Shop brought in her own sewing skills. challenges social prejudices regarding dementia and the brutality, and reflect the meaning of the 'the provision of care for the elderly' in a circle around bond of the mother-in-law and daughter-in-law There is difference of the producig region of made in Switzerland and made in Japan. Nevertheless, women's solidarity and alone 'late blooming flowers, cut back, even if the theme of encapsulate life through a person as a new subject to buy back more than once on the community have to be made is significant hope.

• Applied Biological Chemistry
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• v.20 no.2
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• pp.182-187
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• 1977

This investigation was to determine the changes in the trypsin inhibitor activity(TIA) and electrophoresis patterns of the soybean cotyledon and axis during germination. The TIA of the cotyledon decreased slightly and that of the axis decreased rapidly to 50% activivity after 7 day germination. At the 2nd, 3rd and 4th day's germination the TIA of the defatted dry axis was higher than that of cotyledon. However, the TIA of the fresh cotyledon was lower than that of the axis, due to its higher moisture content. Results from the electrophoretic studies showed that band 1 (polymer, 15S etc.), 2(11S), and 3(7S) whichare the major reserve proteins of soybean were decreased consid erably in cotyledon and axis and the fragments with Rm values between 0.5 and 1.0 were increased and band 5 showed up during germination. The band 4 of the cotyledon and band 6 of axis were not changed during germination. Generally speaking, the TIA and thereserve protein decreased as germination proceed.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.30 no.2
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• pp.291-296
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• 1997

The dietary fiber contents of seaweeds including Drown algae (Undaria pinnatifida, Laminaria japonica, Hizikia fusiforme), red algae (Gelidium amansii, Gracilaria verrucosa) and green algae (Ulva lactuca) and the extraction condition of the fiber was investigated. The dietary fiber contents of Undaria pinnatifida, Laminaria japonica, Hizikia jusiforme, Gelidium amansii, Gracilaria verrucosa and Ulva lactuca were $47.2\%,\;50.7,\;42.6\%,\;48.8\%,\;44.5\%\;and\;40.0\%$, respectively. It was effective to extract soluble dietary fiber with sodium salts such as disodium carbonate and disodium EDTA in brown algae. In red algae, it was effective to extract soluble dietary fibre with disodium EDTA. Also, the extraction time and temperature affected the yields of dietary fiber.

• The Journal of the Acoustical Society of Korea
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• v.9 no.4
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• pp.18-32
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• 1990

Deeping on purpose, SAW device may have to function while immersed in a liquid. Those who are familiar with SAW devices would anticipate difficulty since the propagating surface waves will tend to radiate energy into the liquid and hence suffer attenuation. Thus, to design an immerable SAW device, more attention and full information about the wave properites is required to overcome the attenuation and get the highest SAW generation eficiency. Though numerical simulation, the optimal geometry of underwater SAW devices, such as optimal piezoelectric crystal cut, SAW propagation direction and nondimensional wave number(ka) is determined to get the maximum SAW excitation efficiency, the minimum attenuation in propagation and pure mode propagation for all the modes of surface wave propagation. The design technique can be appliedto an arbitrary combination of a piezoelectric layer, a substrate and a liquid medium. In this paper, PZT and PVDF layers and a steel substrate are use for the solid medium. The technique can be easily employed for the design of underwater sensors and actuators for the applications, such as sonar marine antifouling, industrial and medical uses.

• Microbiology and Biotechnology Letters
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• v.11 no.1
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• pp.67-74
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• 1983

The studies on the color improvement of the Doenjang (two types of fermented soybean paste : soybean Doenjang and modified Doenjang) using various Aspergillus oryzae strains (6 strains : A, B, C, D, E, F) were conducted with the series of experiments of enzymatic activities (pretense, $\alpha$-and $\beta$-amylase), browning color formation (Lovibond color), major chemical components (amino nitrogen, reducing sugar and others) and sensory evaluation (color, taste and odor). Aspergillus oryzae 2157 (C strain) had a high potential for the color improvement of Doenjang products and was identified as non-browning strain during Doenjang fermentation and storage period. And also this strain was appeared to be in good enzyme activities and flavor characteristics.

• Microbiology and Biotechnology Letters
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• v.31 no.2
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• pp.129-134
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• 2003

The purpose of the present study was to screen the effective of lactic acid bacteria (LAB) as probiotics, which are able to protect aquacultural fish pathogenic bacteria, and investigate their characterization. Twenty strains of lactic acid bacteria were isolated from fish intestine, fermented fish foods and kimchis. These bacteria were screened for antagonistic activity against fish pathogenic bacteria. Seven tested LAB strains were able to inhibit the fish pathogenic bacteria, including Vibrio anguillarum, Edwardsiella tarda, and Streptococcus sp.. Of the probiotic candidates, BK19 strain isolated from fermented pollack viscera indicated the largest inhibition activity. Moreover, this strain showed a resistance over low pH and antibiotic agents. Therefore this probiotic candidate BK19 was finally selected and identified as a probiotic strain. This particular probiotic bacteria was identified as Lactobacillus sakei BK19 by biochemical characteristics and 165 rRNA PCR amplification.

• The Journal of the Korea Contents Association
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• v.14 no.7
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• pp.196-216
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• 2014

The purpose of this study was to analyze the social activity, self-efficacy and psychological well-being of old aged people living in Seoul area. For the study, 396 questionnaires were collected to analyzed the effect of demographic characteristics and social activity on psychological well-being, and the moderate effect of self-efficacy on them. The result were as follows: First, there were partial differences in psychological well-being according to demographic characteristics. Second, satisfaction for their lives was positively affected by vocation, health, youth and the social activity. Third, a spouse, health, income and social activity had a negative effect on their loneliness. Forth, a spouse, children, health, more social activity had a negative effect on their depression. Finally, the self-efficacy had a moderate effect on the relation between social activity and loneliness, and depression respectively.