• 대한영양사협회학술지
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• 제4권2호
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• pp.160-167
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• 1998

Current status of nutrient fortification in processed food in Korea were presented by analyzing the information shown on food labels. The obtained information was assessed by the regulations on food fortification in both Korea and other countries including Codex. The most current regulations were gathered from internet. The results are summarized as follows. 1. Major nutrients fortified were calcium, Vit C, Vit B complex, iron and fiber. The forfified foods were not limitted to certain food group with more frequent fortification in snackfoods, cereal, ramyun, retort pouch foods, milk, and youguart. The descriptive terms of nutrition label for the fortification were various including high, supplemented, added, source, fortified, and abundance though the difference among these terms were not distinct. 2. Current regulation on nutrition label requires to give the content of the fortified nutrient and % RDA. However not all of food items carry above information. Also some ingredients such as chitosan, DHA, taurine, $\omega$-3 fatty acid, chondrichin, bifidus were supplemented mainly to the snack foods which FDA(USA) does not allow to be fortified. 3. The nutrient most frequently fortified was calcium and general practice of fortification appears to follow the regulation in Korea. Presently the regulation itself is not well described, this nutient fortification can cause toxic effect. Since calcium was supplemented to wide range of food group consumers who are not conscious of the safe upper limit may intake the fortified food up to the level of 2g/day. 4. For the effective fortification in Korea, the regulation on fortification should be reformed in accordance with the international guideline Codex and the regulations in other countries especially in America and Japan.

• 대한한방부인과학회지
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• 제23권1호
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• pp.83-96
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• 2010

Purpose: A survey was conducted by questionnaire to investigate outpatients' intake status of health food. Methods: The survey of visiting oriental OB&GY clinic in 4 hospitals of oriental medicine and 1 oriental medical clinic has found the status of health food intake. Results: 1. Total respondents were 339(Male: 54, Female: 264) and their average age was $41.4{\pm}11.8$. Outpatients of oriental medicine clinic were 113, outpatients of hospitals of oriental medicine were 226. 2. Among the respondents, 156(40%) persons were taking health food as of today and the proportion of health food intake by oriental medicine clinic's outpatients is higher than the proportion of outpatients of hospitals of oriental medicine. 3. There is no difference in educational background and income among the outpatients who visited the oriental medicine clinic or hospitals of oriental medicine. And the middle income group's health food intake ratio was the highest. 4. The survey showed that heath food intake ratio got higher as persons became old. 5. Among the health foods, the multi-vitamin was most frequently taken. And omega 3, Ginseng steamed red, Vitamin C, Glucosamine, Calcium m were also frequently taken. Conclusion: A study for health food intake status by clinic is indispensable to establish the standard for efficient intake of health food.

• 한국진공학회:학술대회논문집
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• 한국진공학회 1999년도 제17회 학술발표회 논문개요집
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• pp.213-213
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• 1999

현재 LCD용 기판재료는 ITO/glass를 전극으로 사용하고 있다. 그러나 유리기판은 무겁고 깨지기 쉽기 때문에 사용상 곤란한 점이 많다. 최근 flexible하고 가공성 및 생산성이 우수한 플라스틱한 ITO를 성막하여 EL용, Touch panel, plastic LCD용 사용하려는 시도로, roll-to-roll 연속 스퍼터링에 의한 ITO성막공정에 대한 연구가 최근 활발하게 이루어지고 있다. 폴리머는 유리에 비해 Tg 온도가 낮고, 기판으로부터의 수분 및 여러 종류의 가스방출이 심하기 때문에 유리와는 달리 ITO막의 제조에 있어 큰 차이점이 있다. 따라서, 폴리머에 반응성 스퍼터링을 하기 위해서는 표면처리가 중요한 변수가 되며, roll to roll sputter로 ITO 필름을 얻기 위해서는 폭과 길이 방향으로 균일한 막을 얻는 것이 중요하다. 두께 75$\mu\textrm{m}$, 폭 190mm, 길이 400m로 권취된 광학용 Polyethylene terephthalate(PET:Tg:8$0^{\circ}C$)위에 In-10%Sn의 합금타겟과 Unipolar pulsed DC power supply를 사용하여 반응성 마그네트론 스퍼터링 방법으로 0.2m/min의 속도로 연속 스퍼터링 하였다. PET를 Ar/O2 혼합가스로 플라즈마 전처리를 한 후, AFM, XPS를 이용하여 효과를 분석을 하였고, 성막전에 가스방출을 막기 위해 TiO를 코팅하였다. Pilot 연속 생산공정에서 재현성을 위해 PEM(Plasma Emission Monitor)의 optical emission spectroscopy를 이용, 금속과 산화물의 천이구역에서 sprtter된 I/Sn 이온과 산소 이온의 반응에 의한 최적의 플라즈마의 강도값을 입력하여 플라즈마의 radiation을 검출하고, 스퍼터링 공정중 실질적인 in-situ 정보로 이용하였다. PEM을 통하여 In/Sn의 플라즈마 강도변화를 조사하였다. 초기 In/Sn의 플라즈마 강도(intensity)는 강도를 100하여, 산소를 주입한 결과, plasma intensity가 35 줄어들었고, 이때 우수한 ITO 박막을 얻을 수 있었다. Pulsed DC power를 사용하여 아크 현상을 방지하였다. PET 상에 coating 된 ITO 박막의 표면저항과 광투과도는 4-point prove와 spectrophotometer를 이용하여 분석하였고, AES로 박막의 두께에 따른 성분비를 확인하였다. ITO 박막의 광투과도는 산소의 유량과 sputter 된 In/Sn ion의 plasma emission peak에 따라 72%-92%까지 변화하였으며, 저항은 37$\Omega$/$\square$ 이상을 나타내었다. 박막의 Sn/In atomic ratio는 0.12, O/In의 비율은 In2O3의 화학양론적 비율인 1.5보다 작은 1.3을 나타내었다.

• 수산해양기술연구
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• 제26권3호
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• pp.282-287
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• 1990

종래의 전달매트릭스법과 Frontal 전달매트릭스법에 있어서의 계산의 안정성과 효율성을 검토하고 또 이 두 방법에 선형내삽법을 적용하여 각 방법에 의한 해의 수렴특성을 분석한 결과를 요약하면 다음과 같다. 1. 시행값이 작을 경우 두 방법에 의한 계산의 안정성이나 정확성의 면에서 전혀 차이가 없으나, 시행값이 커질수록 전달매트릭스법에 의한 계산의 오차가 증대해지고, 어느 시행값이 이상이 되면 계산이 불안정해 진다. 2. Frontal 전달 매트릭스법은 시행값의 선택에 큰 제약을 받으며, 적절한 시행값을 선택하지 못 했을 경우, 원하는 해를 구할 수 없다. 3. Frontal 전달 매트릭스법에 의한 시행값-진동수행렬식의 값이 plot에 있어서는 불연속점이 존재하고, 이 불연속점을 경계로 plot는 + 혹은 -의 최대값으로 발산하며 다시 새로운 연속구간이 시작된다. 양단의 경계조건이 같을 경우에는 +에서 -로 바뀌는 연속구간내에, 양단의 경계조건이 다를 경우에는 -에서 +로 바뀌는 연속구간내에 해가 존재한다. 4. 선형내삽법을 적용할 때 근사해로의 수렴에 필요한 반복회수는 Frontal 전달 매트릭스법이 훨씬 많으며 한 시행값에 대한 계산시간도 더 많이 필요하므로 근사해를 구하는 전체적인 계산시간은 연속매트릭스법에 비해 훨씬 더 많이 소요된다. 5. Frontal 연속매트릭스법에 의한 계산은 경계조건이나 중간조건에 따라 매트릭스 요소를 기지와 미지로 재배치해야 하고 또는 시행값의 선택이나 불연속구간의 판별 등 많은 제약이 따르므로 프로그램의 작성과 그 실행이 연속매트릭스법에 비해 훨씬 번거롭다.

• 한국환경과학회지
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• 제12권3호
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• pp.265-274
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• 2003

The Pasquill-Gifford stability category is a very important scheme of the Gaussian type dispersion model defined the complex turbulence state of the atmosphere by A grade(very unstable) to F grade(very stable). But there has been made a point out that this stability category might decrease the predictability of the model because it was each covers a broad range of stability conditions, and that they were very site specific. The APSM (Air Pollution Simulation Model) was composed of the turbulent parameters, i.e. friction velocity(${\mu}$$\_$*/), convective velocity scale($\omega$$\_$*/) and Monin-Obukhov length scale(Ｌ) for the purpose of the performance increasing on the case of the unstable atmospheric conditions. And the PDF (Probability Density Function)model was used to express the vertical dispersion characteristics and the profile method was used to calculate the turbulent characteristics. And the performance assessment was validated between APSM and EPA regulatory models(TEM, ISCST), tracer experiment results. There were very good performance results simulated by APSM than that of TEM, ISCST in the short distance (<1415 m) from the source, but increase the simulation error(%) to stand off the source in others. And there were differences in comparison with the lateral dispersion coefficient($\sigma$$\_$y/) which was represent the horizontal dispersion characteristics of a air pollutant in the atmosphere. So the different calculation method of $\sigma$$\_$y/ which was extrapolated from a different tracer experiment data might decrease the simulation performance capability. In conclusion, the air pollution simulation model showed a good capability of predict the air pollution which was composed of the turbulent parameters compared with the results of TEM and ISCST for the unstable atmospheric conditions.

• Wind and Structures
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• 제27권2호
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• pp.101-109
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• 2018

Wall jet flow exists widely in engineering applications, including the simulation of thunderstorm downburst outflows, and has been investigated extensively by both experimental and numerical methods. Most previous studies focused on the scaling laws and self-similarity, while the effect of lip thickness and external stream height on mean velocity has not been examined in detail. The present work is a numerical study, using steady Reynolds-Averaged Navier Stokes (RANS) simulations at a Reynolds number of $3.5{\times}10^4$, of a turbulent plane wall jet with an external stream to investigate the influence of the wall jet domain on downstream development of the flow. The comparisons of flow characteristics simulated by the Reynolds stress turbulence model closure (Stress-omega, SWRSM) and experimental results indicate that this model may be considered reasonable for simulating the wall jet. The confined wall jet is further analyzed in a parametric study, with the results compared to the experimental data. The results indicate that the height and the width of the wind tunnel and the lip thickness of the jet nozzle have a great effect on the wall jet development. The top plate of the tunnel does not confine the development of the wall jet within 200b of the nozzle when the height of the tunnel is more than 40b (b is the height of jet nozzle). The features of the centerline flow in the mid plane of the 3D numerical model are close to those of the 2D simulated plane wall jet when the width of the tunnel is more than 20b.

• 대한의생명과학회지
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• 제11권3호
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• pp.355-363
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• 2005

This study aimed to investigate the cerebroprotective effect of vascular endothelial growth factor (VEGF) on permanent focal cerebral ischemia in Sprague-Dawley rats. Right middle cerebral artery (MCA) was occluded for 6 and 24 hours by an intraluminal monofilament technique. An open cranial window was made on the right parietal bone for determination of continuous changes in regional cerebral blood flow (rCBF) by laser-Doppler flowmetry. The infarct size was morphometrically determined using the 2,3,5-triphenyltetrazolium chloride technique. Brain edema was determined by measuring brain water content. In normal rats, rCBF was significantly increased by intravenous infusion of VEGF for 10 minutes. The VEGF-induced increase in rCBF was significantly inhibited by pretreatment with suramin, a heparin-binding growth factor inhibitor as well as $N^{\omega}-nitro-L-arginine$, a nitric oxide synthase inhibitor. In focal cerebral ischemic rats, the amplitude of decrease in rCBF during ischemic period was significantly less in VEGF-treated group, compared with that in vehicle-treated group. The cerebral infarct size was reduced by VEGF in a dose-dependent manner. The brain edema formation was dose-dependently reduced by VEGF in 24-hour MCA occlusion group but not in 6-hour MCA occlusion group. It is suggested that VEGF not only improves the rCBF during cerebral ischemic period but also reduces the brain edema formation, and thereby exert a protective effect on focal cerebral ischemia in rats.

• BMB Reports
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• 제36권6호
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• pp.593-596
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• 2003

The effects of $N{\omega}$-nitro-L-arginine methylester (L-NAME) and L-arginine on cardiotoxicity that is induced by doxorubicin (Dox) were investigated. A single dose of Dox 15 mg/kg i.p. induced cardiotoxicity, manifested biochemically by a significant elevation of serum creatine phosphokinase (CPK) activity [EC 2.7.3.2]. Moreover, cardiotoxicity was further confirmed by a significant increase in lipid peroxides, measured as malon-di-aldehyde (MDA) in cardiac tissue homogenates. The administration of L-NAME 4 mg/kg/d p.o. in drinking water 5 days before and 3 days after the Dox injection significantly ameliorated the cardiotoxic effects of Dox, judged by the improvement in both serum CPK activity and lipid peroxides in the cardiac tissue homogenates. On the other hand, the administration of L-arginine 70 mg/kg/d p.o. did not protect the cardiac tissues against the toxicity that was induced by the Dox treatment. The findings of this study suggest that L-NAME can attenuate the cardiac dysfunction that is produced by the Dox treatment via the mechanism(s), which may involve the inhibition of the nitric oxide (NO) formation. L-NAME may, therefore, be a beneficial remedy for cardiotoxicity that is induced by Dox and can then be used to improve the therapeutic index of Dox.

• Composites Research
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• 제30권1호
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• pp.41-45
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• 2017

Magnetite nanoparticles were synthesized by adding an ammonium hydroxide to a mixed solution of iron (II) and (III) chlorides. A silicon surfactant of ${\alpha},{\omega}$-(3-aminopropyl)polydimethylsiloxane was adsorbed on the particles as dispersant and a polydimethylsiloxane polymer was used to prepare ferrofluids of silicone oil base. Fluorinated surfactants of anionic ammoniated perfluoroalkyl sulfonamide and nonionic fluoroaliphatic polymeric esters were applied to the particles and a perfluoropolyether was used to prepare ferrofluids of fluorine oil base. The experimental conditions were used for preparing the ferrofluids with concentrations of 200, 300 and 400 mg/mL, and density, magnetization and viscosity of the products were characterized. The density values increased in proportion to the concentration, indicating 1.11-1.27 g/mL for silicone-oil-based fluids and 1.95-2.10 g/mL for fluorine-oil-based fluids in the range of 200-400 mg/mL. The saturation magnetization of the silicone-oil-based and fluorine-oil-based fluids indicated 14.7, 24.4, and 30.7 mT and 15.8, 23.3, and 33.7 mT for 200, 300, and 400 mg/mL, respectively, depending on the content of magnetic particles in the fluid. The viscosity of the silicone-oil-based ferrofluids was highly stable compared to that of the fluorine-oil-based with increasing temperatures. The ferrofluids are usually applied to seals and speakers with the silicone base and to seals with the fluorine base.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.257.1-257.1
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• 2014

We investigated characteristics of ITO/Ag-Pd-Cu (APC)/ITO multilayer electrodes prepared by direct current magnetron sputtering for use as an anode in organic solar cells (OSCs). To optimize electrical properties of ITO/APC/ITO multilayer, we fabricated the ITO/APC/ITO multilayer at a fixed ITO thickness of 30 nm as a function of APC thickness. Compare to the surface of Ag layer on ITO, the APC had a smooth surface morphology. At optimized APC thickness of 12 nm, the ITO/APC/ITO multilayer exhibited a sheet resistance of $6{\Omega}/square$ and optical transmittance of 84.15% at a wavelength of 550 nm which is comparable to conventional ITO/Ag/ITO multilayer. However, the APC-based ITO multilayer showed a higher average transmittance in a visible region than the Ag-based ITO multilayer. The higher average transmittance of ITO/APC/ITO multilayer indicated the multilayer is suitable anode for organic solar cells with P3HT:PCBM active layer. OSCs fabricated on the optimized ITO/ACP/ITO multilayer exhibited a better performance with a fill factor of 64.815%, a short circuit current of $8.107mA/cm^2$, an open circuit voltage of 0.59 V, and power conversion efficiency (3.101%) than OSC with ITO/Ag/ITO multilayer (2.8%).