The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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Availability of Diagnosis of Yin-deficiency in Elderly People with Xerostomia and Factors Influencing Subjective Oral Dryness: A Prospective Cross-sectional Study

노인 구강건조증에 대한 음허 진단의 유용성 및 주관적 구강건조감의 영향요인 : 전향적 단면 조사 연구

  • Kim, Juyeon (3rd Department of Internal Medicine, Hospital of Korean Medicine, Kyung Hee University) ;
  • Kim, Jinsung (3rd Department of Internal Medicine, Hospital of Korean Medicine, Kyung Hee University) ;
  • Park, Jaewoo (Department of Internal Medicine, Hospital of Korean Medicine at Gangdong, Kyung Hee University) ;
  • Ryu, Bongha (3rd Department of Internal Medicine, Hospital of Korean Medicine, Kyung Hee University)
  • 김주연 (경희대학교 한방병원 3내과) ;
  • 김진성 (경희대학교 한방병원 3내과) ;
  • 박재우 (강동경희대학교 한방병원 내과) ;
  • 류봉하 (경희대학교 한방병원 3내과)
  • Received : 2013.02.20
  • Accepted : 2013.04.08
  • Published : 2013.09.30
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Abstract

Objectives: The aims of this study were to investigate the availability of diagnosis of Yin-deficiency in the elderly with xerostomia and factors influencing subjective oral dryness. Methods: We surveyed 50 patients recruited by the clinical trial, 'Efficacy of Yukmijihwang-tang on Xerostomia in the Elderly: A Randomized, Double-blind, Placebo-controlled, Two-center Trial'. The subjects were assessed on their subjective oral dryness using the Dry Mouth Symptom Questionnaire (DMSQ). Their salivary functions were measured by Unstimulated Salivary Flow Rate (USFR) measurements. In addition, the subjects were evaluated on their Qi-stagnation and Yin-deficiency conditions using the Qi-stagnation questionnaire and Yin-deficiency questionnaire. Results: There were statistically significant correlations between three variables (USFR, DMSQ score and Qi-stagnation score) and Yin-deficiency score. In the multiple regression analysis, the regression model was statistically significant (F = 10.273, p < .001). The factor most strongly influencing the subjective oral dryness was USFR (${\beta}$ = -0.386). Yin-deficiency had the next strongest impact on the subjective oral dryness (${\beta}$ = 0.371). Qi-stagnation affected the subjective oral dryness weakly (${\beta}$ = 0.075). In the simple regression analysis, Yin-deficiency had a statistically significant effect on each of six subscales of DMSQ (p < .01). Among the six subscales, DMSQ-1 ('Oral dryness at night or on awakening') was the most strongly influenced by Yin-deficiency. Conclusions: The results of this study show that the diagnosis of Yin-deficiency in the elderly with xerostomia was available and Yin-deficiency was an important factor influencing the subjective oral dryness. Therefore, the consideration of Yin-deficiency is significant for diagnosis and treatment in the elderly with xerostomia.

Keywords

Acknowledgement

Supported by : 보건복지가족부

References

  1. Park MS, Ryu SA. Degree of Dry Mouth and Factors Influencing Oral Health-related Quality of Life for Community-Dwelling Elders. J Korean Acad Nurs. 2010;40(5):747-55. https://doi.org/10.4040/jkan.2010.40.5.747
  2. Ship JA. Diagnosing, managing, and preventing salivary gland disorders. Oral Dis. 2002;8(2):77-89. https://doi.org/10.1034/j.1601-0825.2002.2o837.x
  3. Fox PC, van der Ven PF, Sonies BC, Weiffenbach JM, Baum BJ. Xerostomia: evaluation of a symptom with increasing significance. J Am Dent Assoc. 1985; 110(4):519-25.
  4. Atkinson JC, Wu A. Salivary gland dysfunction: causes, symptoms, treatment. J Am Dent Assoc. 1994;125: 409-16.
  5. Guggenheimer J, Moore PA. Xerostomia: etiology, recognition and treatment. J Am Dent Assoc. 2003; 134(1):61-9. https://doi.org/10.14219/jada.archive.2003.0018
  6. Oh JK, Kim YJ, Kho HS. A Study on the Clinical Characteristics of Patients with Dry Mouth. Korean Academy of Orofacial Pain and Oral Medicine. 2002;26(4): 331-43.
  7. Hopcraft MS, Tan C. Xerostomia: an update for clinicians. Aust Dent J. 2010;55(3):238-44. https://doi.org/10.1111/j.1834-7819.2010.01229.x
  8. Cohen-Brown G, Ship JA. Diagnosis and treatment of salivary gland disorders. Quintessence Int. 2004;35: 108-23.
  9. Fox PC. Management of dry mouth. Dental Clinics of North America. 1997;41:863-75.
  10. Lowman RM, Cheng GK. Diagnostic Roentgenology. In disease of the salivary glands. 1980, W.B. Saunders Co. p.54-98.
  11. Navazesh M, Christensen CM. A comparison of whole mouth resting and stimulated salivary measurement procedures. J Dent Res. 1982;61 (10):1158-62. https://doi.org/10.1177/00220345820610100901
  12. Wang SL, Zhao ZT, Li J, Zhu XZ, Dong H, Zhang YG. Investigation of the clinical value of total saliva flow rates. Arch Oral Biol. 1998;43: 39-43. https://doi.org/10.1016/S0003-9969(97)00092-7
  13. Spielman A, Ben-Aryeh H, Gutman D, Szargel R, Deutsch E. Xerostomia diagnosis and treatment. Oral Surg Oral Med Oral Pathol. 1981;51(2):144-7. https://doi.org/10.1016/0030-4220(81)90031-1
  14. Screebny LM. Xerostomia (Dry mouth). In the salivary system, Screebny LM. Ed., Boca Raton, 1988, CRC Press, Inc., pp.179-202.
  15. Chae BY. Donguianibiinhugwahak. Seoul: Jipmoondang. 2011:444, 461-2.
  16. Lee SJ, Park JB, Lee SS, Kim KH. Development of Yin-Deficiency Questionnaire and Examine the Reliability and Validity. Korean J Oriental Physiology & Pathology. 2004;18(2):376-80.
  17. Lee JY, Lee YO, Kho HS. Reliability of a Questionnaire for Evaluation of Dry Mouth Symptoms. Korean Journal of Oral Medicine. 2005;30(4):383-9.
  18. Navazesh M, Christensen CM. A comparison of whole mouth resting and stimulated salivary measurement procedures. J Dent Res. 1982;61 (10):1158-62. https://doi.org/10.1177/00220345820610100901
  19. Derasawa Gasseutosi. Seoyanguihakjaui Hanbangjillyohak. Seoul:Jipmoondang. 1998:41-58.
  20. Cassolato SF, Turnbull RS. Xerostomia: clinical aspects and treatment. Gerodontology. 2003;20 (2):64-77. https://doi.org/10.1111/j.1741-2358.2003.00064.x
  21. Ikebe K, Matsuda K, Morii K, Wada M, Hazeyama T, Nokubi T. Impact of dry mouth and hyposalivation on oral health-related quality of life of elderly Japanese. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;1:216-22.
  22. Jang JH, Kim SH. The Relationship between Xerostomia and Depression in Elderly People. Journal of Korean Society for Health Education and Promotion. 2007;24(3):51- 60.
  23. Bergdahl M, Bergdahl J. Low unstimulated salivary flow and subjective oral dryness: association with medication, anxiety, depression, and stress. J Dent Res. 2000;79(9):1652-8. https://doi.org/10.1177/00220345000790090301
  24. Locker D. Subjective reports of oral dryness in an older adult populations. Community Dent Oral Epidemiol. 1993;21(3):165-8. https://doi.org/10.1111/j.1600-0528.1993.tb00744.x
  25. Han GJ, Kim JS, Seon JK, Son JH, Oh SW, Park YS, et al. Correlation between Xerostomia, Stress and Qi Movement Stagnation in Halitosis Patients. Korean J Orient Int Med. 2010;31(3): 488-99.
  26. Hoe Jun. Donguibogam. Seoul:Namsandang. 2004:81, 339.
  27. Choi SM, Yang KS, Choi SH, Park KM, Park JH, Shim BS, et al. Standardization and unification of the terms and conditions used for diagnosis in oriental medicine III. Korean J Ori Med. 1997;3(1):41-65.
  28. OOsterberg T, Landahl S, Hedegaard B. Salivary flow, saliva pH, buffering capacity in 70-year-old men and women. Correlation to dental health, dryness in the mouth, disease and drug treatment. J Oral Rehabil. 1984;11:157-70. https://doi.org/10.1111/j.1365-2842.1984.tb00565.x

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