• Title, Summary, Keyword: Xerostomia

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The Relationship between Xerostomia and Depression in Elderly People (노인의 구강건조증과 우울과의 관계)

  • Jang, Jong-Hwa;Kim, Sook-Hyang
    • Korean Journal of Health Education and Promotion
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    • v.24 no.3
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    • pp.51-60
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    • 2007
  • Objectives: This study was to investigate the level of xerostomia and depression in the elderly people and to determine the relationship between xerostomia and depression. Methods: The subjects were 238 subjects(86.5%), who were 65 years or older with mean age of 73.6 years. Data was collected using a self administrated questionnaire from September 14 to September 23, 2005. Perception of xerostomia was measured by questionnaire, and depression was measured using the 20-items CES-D. The data were analysed with t-test, one-way ANOVA, pearson correlation coefficient and multiple regression using the SPSS 12.0 Windows. Results: Regarding xerostomia, the subjects was a mean of 7.87 out of a maximum 12 points. The level of depression in the group of people 65 years or older was 21.51 out of a maximum 60 points. Xerostomia was positive related depression in this study. Perceived oral health and xerostomia had a significant impact on depression. Conclusion: Based on the findings, the perception of xerostomia is strongly associated with depression. These results suggest that oral health promotion should be considered various psychological factors related xerostomia in elders.

Xerostomia and halitosis : A review and current concepts (구강건조증과 구취 : 최신 지견의 고찰)

  • Lee, Yeon-Hee
    • The Journal of the Korean dental association
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    • v.55 no.9
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    • pp.640-656
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    • 2017
  • Xerostomia is usually caused by a reduced salivary flow or by changes in the biochemical composition of saliva. Halitosis or oral malodor is an offensive odor usually originating from the oral cavity. Halitosis can lead to anxiety and psychosocial embarrassment. The occurrence of halitosis closely related with intraoral conditions including the presence of xerostomia. Especially, the relationship between xerostomia and halitosis is prominent in elderly patients receiving polypharmacy with at least two systemic diseases. This study is a review of the update literature of xerostomia and halitosis. A large number of papers have been searched and identified using the words , , , , , , and . Papers not relevant to the issue were removed reducing the entries to 79 only. Most of identified papers were systematic reviews, non-systematic reviews, and observational studies. With a proper diagnosis, identification of the etiology and timely referrals certain steps are taken to create a successful individualized therapeutic approach. It is significant to highlight the necessity of an interdisciplinary method for the treatment of xerostomia and halitosis to prevent misdiagnosis or unnecessary treatment. This article concisely focuses on the development of a systemic flow of events to come to the proper treatment of the xerostomia and halitosis.

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The effect of job stress in jobholders on xerostomia (직장인의 직무스트레스가 구강건조감에 미치는 영향)

  • Kim, Myung-Eun
    • Journal of Korean society of Dental Hygiene
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    • v.12 no.1
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    • pp.1-15
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    • 2012
  • Objectives : The purpose of this study was to examine the effect between job stress in jobholders and xerostomia. Methods : 250 jobholders living in Jecheon city were the subjects of this questionnaire. The questionnaire was made up of three contents and 37 items: general characteristic(13), job stress(14), degree & behavior of xerostomia(10). The data were analyzed by two-sample t-test, one-way ANOVA to examine the subjects general characteristics, job stress and degree of xerostomia and were analyzed by Chi-square test to examine the subjects general characteristics, job stress and behavior of xerostomia. Results : Only 215 jobholders were evaluated due to inadequate responses. The results were as follow. 1. As general characteristic of jobholder, male(83.7%) were more than women(16.3%), 30~39 year-old(47%) in age variable, university graduation(63.7%) in the last educational background variable, 2~3 million won(31.2%) in the month average income variable, 1~5 year(33.5%) in tour of duty variable, non-smoker(47.9%) in smoking variable were most. Married(58.6%) were more than unmarried(39.5%). Alcoholic(69.8%) were more than non-alcoholic(30.2%). 2. As classification of job stress, high strain group was 28.4%, active group was 26%, low strain group was 24.2%, passive group was 21.4%. 3. Analysis of effect between general characteristic and degree & behavior of xerostomia showed smoker were statistical significantly higher than non-smoker on 'dry eat', 'Am-sal', 'Night awake', 'Slip-liq'and 'Gumcandy'(p<0.05) and showed alcoholic were statistical significantly higher than non-alcoholic on 'Dry PM', 'Night awake, $H_2O$-bed'(p<0.05). 4. Analysis of effect between job stress and degree & behavior of xerostomia showed hight strain group were statistical significantly higher than low strain group on 'Dry PM', 'Dry-day', 'Am-sal', 'Eff-life'and 'Night awake'(p<0.05). Conclusions : As high strain group were higher than other groups on degree & behavior of xerostomia, stress would be factor that have an effect on xerostomia. Thus consider and management of stress is necessary for diagnosis and treatment of xerostomia.

Design and Implementation of Salivary Electrical Stimulator for xerostomia

  • Lee, Jihyeon;Yeom, Hojun
    • International journal of advanced smart convergence
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    • v.6 no.4
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    • pp.19-25
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    • 2017
  • After 40 years of age, the saliva glands are aged and the saliva is not made enough to cause xerostomia symptoms. Side effects such as hypertension medication or diuretics that the elderly take mainly can cause xerostomia syndrome. In addition, autoimmune diseases, diabetes, anemia, depression and other common diseases that cause xerostomia symptoms. If the saliva secretion is insufficient, tooth decay and gum disease are likely to occur, and the digestive ability of the saliva is also reduced due to the lack of amylase, which is a digestive element. Once the degenerated salivary gland is restored to its normal state, it is difficult to recover. In this paper, we give electrical stimulation to the masseter which is in contact with the large pituitary gland, and stimulate the salivary gland to the utmost by using speech recognition using words corresponding to oral gymnastics. Use the STM32F407VG to implement a system to relieve xerostomia.

Case Report of Unspecified Tremor with Xerostomia Resulting from Psychometric Drug Intake Treated by Traditional Korean Medicine (한방치료로 호전된 상세불명의 떨림과 동반된 정신과계통 약물유발성 구강건조증 치험 1례)

  • Jung, Yu-jin;Kim, Minserh;Hong, Sang-hoon
    • The Journal of Internal Korean Medicine
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    • v.39 no.5
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    • pp.914-928
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    • 2018
  • Objectives: This case report examines the effects of traditional Korean medicine for unspecified tremor with xerostomia caused by psychometric drug intake. Methods: A patient who suffered from unspecified tremor with xerostomia caused by psychometric drug intake was treated with acupuncture, pharmacopuncture, and traditional Korean medicine for 30 days. We provided the patient with herbal medicines including Ondam-tang-gagam (溫膽湯加減), Pumsimgieum-gagam (忿心氣陰加減), and Hoichunyanggyeok-san-gami (回春凉隔散加味). Symptoms were charted and evaluated using the Yin-deficiency questionnaire score, Yin-deficiency scale score, dry mouth symptom questionnaire, and visual analogue scale. Results: After treatment with Korean Medicine and pharmacopuncture, the frequency and degree of tremor has decreased, and degree of Xerostomia also improved. The Scores of Yin-deficiency questionnaire score, Yin-deficiency scale score, dry mouth symptom questionnaire, and visual analogue scale were also improved. And we could see reduction in the level of distribution of gastrointestinal heat at Digital Infrared Thermal Imaging test. The patient's Symtoms (Xerostomia as well as unspecified tremor) were improved after treated with Korean Medicine and pharmacopuncture. Conclusion: Korean medicine treatments may be valuable for xerostomia caused by psychometric drug intake.

Preliminary study on the efficacy of xerostomia treatment with sialocentesis targeting thyroid disease patients given radioiodine therapy

  • Kim, Euy-Hyun;Lee, Dong-Keon;Kim, Chang-Woo;Song, In-Seok;Jun, Sang-Ho
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.41
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    • pp.39.1-39.6
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    • 2019
  • Background: Radioiodine therapy has been widely used for thyroid disease patients, but hyposalivation and xerostomia may occur in 10~30% of patients. Sialocentesis is a procedure that removes inflammatory substances in the salivary duct and expands the duct for the secretion and delivery of saliva. In this study, thyroid disease patients treated with radioactive iodine were selected among the patients with xerostomia who visited the hospital, and the effect of sialocentesis was compared and analyzed. And then, comparison between the radioiodine therapy-experienced group and the non-radioiodine therapy-experienced group was conducted. Results: In this study, we studied xerostomia patients who underwent radioiodine therapy due to thyroid diseases and who underwent sialocentesis at the Korea University Anam Hospital. Sialocentesis is conducted by one surgeon. The study also compares the clinical symptoms before and after the surgery. After the procedure, the discomfort due to xerostomia was reduced, and the symptom was improved effectively. Conclusions: The results of this study showed that sialocentesis has a clinical effect in the treatment of xerostomia, which is a side effect of radioiodine therapy. In addition, the possibility of further clinical application of sialocentesis in the future is found.

Study on Tongue Coating Patterns of the Xerostomia in the Elderly Patients (노인 구강건조증 환자들의 설태 양상에 관한 고찰)

  • Han, Gajin;Park, Jae-Woo;Ko, Seok-Jae;Kim, Juyeon;Son, Jiyoung;Jang, Seungwon;Kim, Seul-Ki;Kim, Minji;Kim, Jinsung
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.17 no.3
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    • pp.189-202
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    • 2013
  • Objectives The aim of this study is to analyze the characteristics of the tongue coating pattern in the elderly patients with xerostomia. Methods Ninety-six elderly patients with xerostomia were recruited by advertisement and they visited the oral diseases clinics at Kyung Hee University Korean Medicine Hospital and Kyung Hee University Hospital at Gangdong from November, 2011 to August, 2013. After signifying the assent, the subjects who passed screening were enrolled this study. The subjects were evaluated on their clinical characteristics of xerostomia using visual analogue scale for xerostomia, dry mouth questionnaire, unstimulated salivary flow rate. In addition, Yin-deficiency questionnaire was used to evaluate the Yin-deficiency state and Winkel tongue coating index and Digital Tongue imagin system were used to measure the tongue coating of patients. Results The proportion of women was higher than that of men, and there were few smokers in this study population. This population had chronic and relatively severe xerostomia symptoms. Also, thin coating pattern was showed in this elderly patients with xerostomia and this result was regarded to the influence of Yin-deficiency. The thin coating patten was observed in the group with higher Yin-deficiency score. There was no difference in tongue coating between the hyposalivation and normosalivation group. Conclusion In the elderly patients with xerostomia, Yin-deficiency is might be considered as one of the main cause of xerostomia. Hence, it is thought that this patients showed the thin coating pattern. This results could be used in diagnosis and treatment for the elderly patients with xerostomia in traditional Korean medicine.

Effects of Cinnamaldehyde on Salivary Gland Tissue in Xerostomia Model

  • Choi, Ja-Hyeong;Lee, Jung-Hwa;Kim, Yeon-Hwa;Hyun, Kyung-Yae;Park, Chung-Mu;Lee, Min-Kyung
    • Biomedical Science Letters
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    • v.26 no.2
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    • pp.93-100
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    • 2020
  • Xerostomia is a relatively common oral disease that causes various problems such as pain, discomforted, tissue damage, and infection. When the activity of AQPs, which plays an important role in the microbial channel transmembrane activity in tissues, decreases saliva secretion and the oral cavity dryness occurs. In this study, we observed whether there was a change in tissue through the expression level of AQP-5 in the submandibular gland in the 4-DAMP-induced xerostomia model. First, in order to construct a xerostomia model, 4-DAMP (1 mg/kg) and 20% urethane (0.5 mL/kg) were administered intraperitoneal (i.p.) to experimental animals. To observe the changes in the submandibular gland was excised, H&E staining was performed and protein quantitation analysis was performed using the submandibular tissue to observe the changes in AQP5 protein expression involved in changes in saliva secretion. Also, cinnamaldehyde (5, 12.5, 25 and 50 mg/kg) dissolved in 20% DMSO, in distilled water for each concentration, and then orally administered at a dose of 1 mL for biopsy and protein quantitative analysis. As a result, it was observed that the submandibular tissue, a model of xerostomia was wider than the naïve group. And then western blot analysis, the expression level of AQP5 decreased in the 4-DAMP group compared to the naïve group, and the expression increased in the group administered orally with cinnamaldehyde. Therefore, administration of 4-DAMP resulted in histological changes for xerostomia, and cinnamaldehyde would be a material that can be developed by reducing xerostomia.

Effects on Salivation, Xerostomia and Halitosis in Elders after Oral Function Improvement Exercises (입체조가 노인의 타액분비량, 구내건조증 및 구취에 미치는 영향)

  • Kim, Young Jin;Park, Kyung Min
    • Journal of Korean Academy of Nursing
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    • v.42 no.6
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    • pp.898-906
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    • 2012
  • Purpose: The purpose of this study was to investigate effects of Oral Function Improvement Exercises on salivation, xerostomia and halitosis in elderly people. Methods: The participants in the study were 48 female community-dwelling elders in D city. The Oral Function Improvement Exercises were given 3 times a week, for a total of 24 times from August to October 2011. Spitting method, Visual Analogue Scale, and halimeter (mBA-21) were used to evaluate the effects of Oral Function Improvement Exercises on salivation, xerostomia, and halitosis. The data were analyzed using ${\chi}^2$-test and t-test with the SPSS program. Results: The experimental group had significantly better salivation, and less xerostomia and halitosis than the control group. Conclusion: The results indicate that Oral Function Improvement Exercises were effective for salivation, xerostomia and halitosis in the elders. Therefore, it was suggested that Oral Function Improvement Exercise are applicable in a community nursing intervention program to improve the quality of life for elders.

Comparisons of the Effects of A-solution and 0.9% Normal Saline Oral Gargling on Xerostomia, Halitosis, and Salivary pH in Nursing Students (아로마용액과 0.9% N/S 구강함수가 간호대학생의 구강건조, 구취 및 타액 pH에 미치는 효과 비교)

  • Cho, Mi-Kyoung;Cho, Yoon Hee
    • Journal of Korean Biological Nursing Science
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    • v.16 no.2
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    • pp.141-149
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    • 2014
  • Purpose: The purpose of this study was to compare the effects of gargling with A-Solution and 0.9% normal saline on xerostomia, halitosis, and salivary pH among nursing students. Methods: The study design was a randomized, controlled trial. The experimental group received oral gargling treatment for 15 seconds with A-solution while the control group received oral gargling treatment for the same time with 0.9% normal saline. Outcome variables were measured at baseline, 60 minutes, and 120 minutes. Results: The groups were homogeneous in general characteristics, and the outcome variables before the treatment between the experimental group and the control group. 1) There were no significant differences in xerostomia, halitosis, and salivary pH between the two groups. 2) There were no significant differences in xerostomia, halitosis, and salivary pH based on the time. 3) There were significant interactions between group and time in subjective halitosis (F=3.766, p=.034) only. Conclusion: These findings indicate that oral gargling with Aroma solution and 0.9% normal saline could have the same effect of reducing xerostomia and halitosis in nursing students.