• 동아시아식생활학회지
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• 제12권2호
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• pp.123-128
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• 2002

시료로부터 chloroform-methanol(2:1/v:v)혼합용매로 추출하여 얻은 조, 기장, 수수의 총지질 함량은 각각 3.9%, 2.7% 및 2.3%였다. 추출한 총지질을 silicic acid column을 이용하여 중성지질, 당지질, 인지질로 분획하고 그 함량을 구한 결과 총지질에서 중성지질, 당지질, 인지질의 함량은 조에서 72.4%, 18.8% 및 8.8%였고, 기장은 69.2%, 21.1% 및 9.6%였으며, 수수는 77.4%, 16.1% 및 6.6%였다. 모든 시료에서 중성지질이 가장 많은 양을 함유하고 있었으며, 각 지방질의 지방산을 GC로 분석한 결과, 모든 시료에서 가장 많은 지방산은 linoleic acid 였고, oleic acid와 palmitic acid가 그 다음으로 많은 양을 나타내었다. 조의 인지질에서 behenic acid가 12.77%로 상당한 양이 검출된 것과 중성지질에서 극히 소량이지만 myristic acid가 검출된 것이 특징적이다. Linolenic acid는 모든 시료에서 검출되지 않았다.

• Journal of Nutrition and Health
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• 제33권4호
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• pp.374-385
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• 2000

The purpose of the present study was to investigate the effect of Korea leek on plasm lipids and platelet aggregation in hypercholesterolemic rats fed different dietary fat. Sprague-Dawley rats were fed with hyperlipidemic diet for 4 weeks in order to induce hyperlipidemia, followed by the feeding of experimental diets for additonal 4 weeks. We used three kinds of lipid(perilla oil, corn oil and lard). Korean leek of experimental diets was prepared by drying and milling. Powdered Cellulose and powdered Korean leek were added to experimental diets at the level of 5% (w/w). Serum concentrations of total lipid, total triglyceride, total cholesterol and LDL-cholesterol decreased in the order of perilla oil, corn oil and lard. Korean leek significantly decreased total lipid, total cholesterol, LDL-cholesterol, platelet count, prothrombin time, and platelet aggregation in rats fed a lard diet. The present observation indicates that Korean leek might be helpful for the prevention and threapy of hyperlipidemia and platelet aggregation.

• 한국식품영양학회지
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• 제20권2호
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• pp.143-149
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• 2007

To examine the effects of pomegranate on cerebral blood flow and obesity, we observed regional cerebral blood flow in normal rats, as well as body weight, serum total cholesterol, serum HDL-cholesterol, serum LDL-cholesterol, serum triglycerides, serum total lipids, serum phospholipids and serum free fatty acid levels in rats fed a high fat diet. The results were as follows. Pomegranate seed extract significantly increased regional cerebral blood flow and the peel extract increased regional the cerebral blood flow in a dose dependent manner. In addition, the pomegranate extracts(seed, peel, juice) decreased body weight, serum total cholesterol, serum LDL-cholesterol, serum triglycerides, serum total lipids, serum phospholipids and serum free fatty acid levels, and increased serum HDL-cholesterol in the rats fed a high fat diet. More specially the seed extract significantly decreased serum total cholesterol, serum triglycerides and serum phospholipid levels.

• Applied Biological Chemistry
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• 제29권4호
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• pp.346-351
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• 1986

이조대맥의 맥아제조시 유리 및 결합지질과 중성지질의 함량변화와 구성지방산의 변화를 조사하였다. 1. 이조대맥의 지질함량 27.9mg/g-d.w.중 유리지질과 결합지질이 각각 22.6, 5.3mg/g-d.w.으로서 유리지질이 대부분을 차지하였으며, 맥아제조시 발아일수가 경과함에 따라 다 같이 감소하였다. 2. 이조대맥의 중성지질의 함량은 21.0mg/g-d.w.으로서 전지질의 75% 정도 차지하였으며, 맥아제조시 발아일수가 경과함에 따라 감소하였다. 3. 이조대맥의 주지질인 중성지질의 조성은 triglyceride가 54.6%로 대부분을 차지하였으며, 다음으로 free fatty acid, free sterol, 1,2-diglyceride, 1,3-diglyceride순이었고, 이들 중 triglyceride는 발아기간중 감소하였으며, free fatty acid와 sterol ester는 증가하였다. 4. 유리지질 및 결합지질의 구성지방산은 다같이 linoleic acid가 50% 이상을 차지하였으며, 다음으로 palmitic acid, oleic acid 등이 주지방산이었다. 그리고 주지방산인 linoleic acid는 발아기간 중 증강이 뚜렷하지 않았으나 palmitic acid는 유리지질에서 증가하는 반면에 결합지질에서는 감소하였고, oleic acid는 유리지질에서 감소하는 반면 결합지질에서 변화하지 않아 뚜렷한 차이를 나타내었다. 5. 중성지질의 구성지방산 조성은 유리지질과 결합지질은 다같이 linoleic acid가 주지방산이었고 다음으로 palmitic acid, oleic acid순이었다. 발아과정중의 구성지방산의 변화는 palmitic acid가 증가하는데 비하여 주지방산인 linoleic acid나 stearic acid가 다소 감소하는 경향이었다.

• 생약학회지
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• 제27권4호
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• pp.397-407
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• 1996

This study was attempted to investigate the effect of Composite Preparation (Sam Whang Sasim-Tang: SWST, Whang Ryun Haedok-Tang: WRHT) on the activities of GOT and GPT, the content of total lipids, triglyceride, total cholesterol. Phospholipid and ${\beta}-lipoprotein$ in the serum, and the change ratio of body and liver weight in the experimentally induced hyperlipemic rats, making use of the extract 150, 200, 300 and 500 mg/kg p.o. Significant test was performed by comparision with the values of corresponding experimentally hyperlipemic rats. The activities of S-GPT was significantly decreased in all dose of SWST and WRHT respectively. The activities of S-GPT was significantly decreased in dose of SWST 500 mg/kg and in all dose of WRHT respectively. The content of total lipids, triglyceride, total cholesterol and phospholipids were significantly decreased in all dose of two the extract. The rate of decrease on total lipids and triglyceride were remarkable in dose of SWST 300, 500 mg/kg and WRHT 200, 500 mg/kg, and then the content of total cholesterol was more remarkable in dose SWST 300, 500 mg/kg, and WRHT 150, 300 mg/kg, and the content of phospholipids was more remarkable in dose of the extract 150, 200 and 300 mg/kg. The content of ${\beta}-lipoprotein$ was significantly decreased in dose of WRHT 150, 200 and in all dose of SWST. Increase ratio of the body and liver weight were significantly decreased in dose of two the extract 300, 500 mg/kg respectively.

• Journal of Nutrition and Health
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• 제24권3호
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• pp.157-165
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• 1991

The purpose of this study was to investigate differences in body fat distribution between normal and obese subjects and the relationship between risk factors(fasting blood sugar, blood pressure. fasting serum lipids) and obesity. Measurements of height. weight, skinfold thickness. body circumference. percent body fat. blood pressure, fasting blood sugar and serum lipids were made and a dietary survey was performed on 120(Males 61. Females 59) adult subjects. 1) Among the female subjects, the obese group appeared to have significantly higher centrality of body fat than the normal group. Obese groups of both sexes appeared with higher blood pressure than normal groups. No differences in daily average nutrient intake, fasting blood sugar and fasting serum lipids concentrations were observed between obese and normal groups. 2) In males. the serum triglyceride concentration was observed to have a significantly positive correlation to body weight, body mass index and body circumference, additionally concentrations of total cholesterol and LDL-cholesterol were observed to have significantly positive correlations to the skinfold thickness. but the ratio of HDL-cholesterol/total cholesterol was observed to be significantly negatively correlated to the skinfold thickness. 3) In females. the obese group consumed about 47% of total energy intake at lunch. whereas the normal group consumed about 29% . The food habit score of males appeared to be negatively related to body weight, percent ideal body weight. But the food habit score of females appeared to be negatively related to percent body fat(r=-0.32, p<0.05) .

• 성인간호학회지
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• 제18권5호
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• pp.809-818
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• 2006

Purpose: The purpose of this study was to evaluate the effect of antioxidant vitamins and magnesium supplementation on fasting blood glucose and lipids in patients with type 2 diabetes. Methods: This study is a unequivalent control group pretest-posttest design. Seventyone subjects with type 2 diabetes who were recruited from home visiting clients of a public health center, completed the trial. The experimental group entered a 12-week treatment period with antioxidant vitamins and magnesium and the control group with no antioxidant vitamins and magnesium. Results: Serum level of fasting blood glucose decreased from $134.7mg/d{\ell}$ to $125.0mg/d{\ell}$ and total-cholesterol decreased from $215.5mg/d{\ell}$ to $198.2mg/d{\ell}$ in the experimental group. No changes in fasting blood glucose and total-cholesterol were demonstrated in the control group. Conclusions: A short-term supplementation with antioxidant vitamins and magnesium can reduce fasting blood glucose and total-cholesterol in patients with type 2 diabetes. The continuous effect of this supplementation and the beneficial effect on the prevention of diabetes complication still needs to be demonstrated.

• 한국식품영양과학회지
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• 제15권4호
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• pp.17-23
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• 1986

This study was designed to observe the effect of Undaria Pinnatifida (U. P.) Powder on serum and liver lipids concentration in rats. Adult male rats of Sprague-Dawley strain were divided into four diet groups: one control diet and the other three diets in which U.P. powder was mixed with the control diet at the rate of 1%, 2% and 3% respectively. The results of the above observation were as follows : Serum and liver total lipids in 3% U.P. group were lower an those in control group at the 6th week. There was no difference in serum and liver total cholesterol among the diet groups. Serum HDL-cholesterol and HDL-cholesterol per total cholesterol ratio in 3% U.P. group were higher than those in control group at the 3rd and 6th week. Serum triglyceride in 3% U.P. group was significantly lower than that in control group at the 3rd week. Serum phospholipid in 1% U.P. and 3% U.P. group was significantly lower than that in control group at the 3rd week, but there was no difference among them at the 6th week.

• 대한임상검사과학회지
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• 제38권2호
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• pp.105-110
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• 2006

This study was carried out to establish the normal values of serum lipids by age and sex for healthy adults and the frequency of dyslipidemia as a risk factor of coronary atherosclerosis. Total cholesterol, triglyceride, and HDL-cholesterol were measured for 14,485 average adults (8,712 males and 5,773 females) aged 20 to 69 years and analyzed using the auto-analyzer Hitach 7600 in enzyme method. Mean values of total cholesterol, LDL-cholesterol and atherogenic index were higher in men than in women at the ages of 20-40 years but significantly higher in women than in men in the age group of 60 years. Theses findings suggest that the mean concentrations of total cholesterol, triglyceride and LDL-cholesterol in men and women vary with age. The frequency of hypercholesterolemia ($${\geq_-}200mg/dL$$) in men and women was about 31.4% and increased with age.

• Applied Biological Chemistry
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• 제29권2호
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• pp.122-129
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• 1986

한국산(韓國産) 옥수수의 지질성분(脂質成分)을 계통적(系統的)으로 분석(分析)하기 위하여 수원(水原)19호(號), 횡성옥(橫城玉), 광옥(廣玉), 황옥(黃玉) 3호(號)의 네가지 품종(品種)을 시료(試料)로 하여 유리지질(遊離脂質)과 결합지질(結合脂質)을 추출(抽出)하고 정제(精製)한 후지질성분(後脂質成分) 및 구성지질산(構成脂質酸構)을 column chromatography, thin layer chromatography, gas liquid chromatography를 이용(利用)하여 분리(分離) 정량(定量)하였다. 옥수수의 총지질(總脂質)의 평균함량(平均含量)은 5.02%로 유리지질(遊離脂質)이 4.09%, 결합지질(結合脂質)이 0.93%를 차지하였다. 유리지질(遊離脂質)은 중성지질(中性脂質) 89.61%, 당지질(糖脂質) 3.75%, 인지질(燐脂質) 6.40%였으나, 결합지질(結合脂質)은 중성지질(中性脂質) 14.26%, 당지질(糖脂質) 46.06%, 인지질(燐脂質) 37.18%로서 유리지질(遊離脂質)에는 중성지질(中性脂質)의 함량(含量)이 높은 반면 결합지질(結合脂質)에는 극성지질(極性脂質)의 함량(含量)이 높았다. 유리지질중(遊離脂質中) 중성지질(中性脂質)의 주성분(主成分)은 triglyceride(67.68%)였으며 결합지질(結合脂質)은 triglyceride(47.88%), free fatty acid(33.44%)로서 유리지질(遊離脂質)에 비하여 free fatty acid의 함량(含量)이 상당(相當)히 높았다. 또한 유리지질(遊離脂質)과 결합지질(結合脂質)의 당지질(糖脂質)은 많은 차이를 보였으며, 인지질(燐脂質)의 주성분(主成分)은 phosphatidyl choline과 phosphatidyl serine이었고, phosphatidyl ethanolamine, phosphatidyl glycerol inositol도 존재하였다. 유리지질(遊離脂質) 및 결합지질(結合脂質)을 구성(構成)하는 주요지방산(主要脂肪酸)은 linoleic acid, oleic acid, palmitic acid였으며, 유리지질(遊離脂質)은 linoleic acid, oleic acid, palmitic acid의 순서(順序)로 함량(含量)이 낮았고, 결합지질(結合脂質)은 linoleic acid의 함량이 가장 많고 palmitic acid, oleic acid의 순서(順序)로 적었다.