• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1119-1123
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• 2014

Head and neck cancers (HNC) are extremely complex disease types and it is likely that chromosomal instability is involved in the genetic mechanisms of its genesis. However, there is little information regarding the background levels of chromosome instability in these patients. In this pilot study, we examined spontaneous chromosome instability in short-term lymphocyte cultures (72 hours) from 72 study subjects - 36 newly diagnosed HNC squamous cell carcinoma patients and 36 healthy ethnic controls. We estimated chromosome instability (CIN) using chromosomal aberration (CA) analysis and nuclear level anomalies using the Cytokinesis Block Micronucleus Cytome Assay (CBMN Cyt Assay). The proliferation rates in cultures of peripheral blood lymphocytes (PBL) were assessed by calculating the Cytokinesis Block Proliferation Index (CBPI). Our results showed a significantly higher mean level of spontaneous chromosome type aberrations (CSAs), chromatid type aberration (CTAs) dicentric chromosomes (DIC) and chromosome aneuploidy (CANE UP) in patients (CSAs, $0.0294{\pm}0.0038$; CTAs, $0.0925{\pm}0.0060$; DICs, $0.0213{\pm}0.0003$; and CANE UPs, $0.0308{\pm}0.0035$) compared to controls (CSAs, $0.0005{\pm}0.0003$; CTAs, $0.0058{\pm}0.0015$; DICs, $0.0005{\pm}0.0003$; and CANEUPs, $0.0052{\pm}0.0013$) where p<0.001l. Similarly, spontaneous nuclear anomalies showed significantly higher mean level of micronuclei (MNi), nucleoplasmic bridges (NPBs) and nuclear buds (NBUDs) among cases (MNi, $0.01867{\pm}0.00108$; NPBs, $0.0156{\pm}0.00234$; NBUDs, $0.00658{\pm}0.00068$) compared with controls (MNi, $0.00027{\pm}0.00009$; NPBs, $0.00002{\pm}0.00002$; NBUDs, $0.00011{\pm}0.00007$).The evaluation of CBPI supported genomic instability in the peripheral blood lymphocytes showing a significantly lower proliferation rate in HNC patients ($1.525{\pm}0.005552$) compared to healthy subjects ($1.686{\pm}0.009520$) (p<0.0001). In conclusion, our preliminary results showed that visible spontaneous genomic instability and low rate proliferation in the cultured peripheral lymphocytes of solid tumors could be biomarkers to predict malignancy in early stages.

• 대한공업교육학회지
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• v.37 no.2
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• pp.147-160
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• 2012

The purpose of this study was to examine the effects on the academic achievement and learning satisfaction according to the presentation method of the multimedia materials for 'transportation technology' units of technology home economics subject. The subjects were assigned in third conditions; Text type explanation class, multimedia class and multimedia video class with narration. The data of six evaluation questions obtained from the survey of 93 high school girl were analyzed using SPSS program. The results of the study were as follows : First, in the learning satisfaction average level(M) of the students' overall responses to the questions, multimedia teaching learning class(experimental group 1) is the first(M=4.14), multimedia video class with narration(experimental group 2) is the second(M=3.16), and instructor-led class(control group) is the third (M=2.63). Therefore, the teaching learning multimedia class(experimental group 1) was most effective. Second, looking at the correlations between the students' responses to the questions, in an interesting class, the students have a retentive memory and comprehension, but a lower concentration can not a retentive memory. Third, multimedia teaching learning class(experimental group 1) has the best degree at the level of academic achievement, but instructor-led class(control group) and multimedia video class with narration(experimental group 2) have similar degree in the second place. To increase academic achievement, an instructor-led class is important to arouse interest and a multimedia video class with narration is required ways to improve level of concentration.

• Journal of Korean Society for Quality Management
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• v.41 no.4
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• pp.725-735
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• 2013

Purpose: The purpose of this study is to propose an Integrated Safety Evaluation Process (ISEP) that can enhances the safety aspect of the safety-critical system. This process utilizes the advantages of the iterative Systems Engineering process combined with the safety assessment process that is commonly and well defined in many standards and/or guidelines for railway, aerospace, and other safety-critical systems. Methods: The proposed process model is based on the predefined system lifecycle, in each phase of which the appropriate safety assessment activities and the safety data are identified. The interfaces between Systems Engineering process and the safety assessment process are identified before the two processes are integrated. For the integration, the elements at lower level of Systems Engineering process are combined with the relevant elements of safety assessment process. This combined process model is represented as Enhanced Functional Flow Block Diagram (EFFBD) by using CORE(R) that is commercial modelling tool. Results: The proposed model is applied to the lifecycle and management process of the United States aircraft system. The US aircraft systems engineering process are composed of twelve key elements, among which the requirements management, functional analysis, and Synthesis processes are considered for examplenary application of the proposed process. To synchronize the Systems Engineering process and the safety assessment process, the Systems Engineering milestones are utilized, where the US aircraft system has thirteen milestones. Taking into account of the nine steps in the maturity level, the integrated process models are proposed in some phases of lifecycle. The flows of processes are simulated using CORE(R), confirming the flows are timelined without any conflict between the Systems Engineering process and the safety assessment process. Conclusion: ISEP allows the timeline analysis for identifying activity and data flows. Also, the use of CORE(R) is shown to be effective in the management and change of process data, which helps for the ISEP to apply for the development of safety critical system. In this study, only the first few phases of lifecyle are considered, however, the implementation through operation phases can be revised by combining the elements of safety activities regarding those phases.

• Journal of the military operations research society of Korea
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• v.32 no.1
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• pp.13-35
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• 2006

This study aims to propose alternative suggestions for practical and efficient implementation of Dual Use Technology Programs(CUTP) in Korea which can strengthen both national security and industrial competitiveness. DUTP of Korea has suffered from inefficiency and inactivity. This study analyzes the Inefficiency and negative factors of DUTP of Korea by examining the previous cases of the advanced countries. It also examines individual problems of DUTP carefully and attempts to derive alternative solutions to improve the current situation. First, a global government plan should be made considering Korea's weapon system and Korea's industrial characteristics. Second, DUTP should begin to develop core technology in connection with technology level evaluation and technology exchange project should establish a comprehensive information network system which links any civilian and military technology data. Third, technology transfer project should be promoted by utilizing cyber technology exchange market and military defense venture center. Fourth, standardization project should be expanded by establishing a national standard information system.

• The Journal of the Korea Contents Association
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• v.10 no.12
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• pp.109-119
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• 2010

Though the productivity increased by 50% as KBCT was the first to use ATC System in Korea, productivity is unlikely to be improved any longer because of unsatisfactory detailed automation technology development. Accordingly, the government embarked on 'high efficiency ATC technology development', but it is important to avoid overlapping with other advanced technology which is already developed, and to develop differentiated technology which has the way about it. To accomplish this, this paper suggested in-depth analysis about established domestic and overseas technologies, clear goal setting to achieve world-class level productivity, and rational development road map for success in technology development. Through this, as to the ATC automatization technology development, the ports of our country precedes in a competition with the ports of the neighboring country, and it will jump to the Northeast Asia Logistics-Hub-port and a role as growth engine for next-generation in our country will be played. In addition, the result of the technology development will become the standard of the performance evaluation of the relative technique of the domestic automated terminal, and will be leads the world in this field of technology.

• Journal of the Korea Institute of Military Science and Technology
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• v.22 no.4
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• pp.545-554
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• 2019

The purpose of this study is to develop a method of applying AR(Augmented Reality)/VR(Virtual Reality) to educational and training systems from a comprehensive perspective, rather than applying AR/VR technology to specific education and training systems. We suggested whether to apply AR or VR technology to education and training system, the level of application of technology when constructing using AR/VR technology, and the criteria of priority among many education and training systems. To do this, we presented the framework of application of AR/VR technology, the evaluation criteria for selecting priority of education and training system applying AR/VR, and the systematic procedure for utilization of developed method. This study is significant in that it has developed a method to determine the direction of systematic AR/VR technology application for all education and training systems operated by the military or organization. This is expected to contribute to the overall efficiency of the organization in terms of economical utilization of the limited budget as well as the various benefits of utilizing basic AR/VR technology.

• Convergence Security Journal
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• v.24 no.2
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• pp.105-121
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• 2024

Korea operates a national core technology system to protect important technologies at the national level. In the administrative procedures of the nation's core technology, the deliberation process conducted by qualitative evaluation by related industry experts is important. As the need for timely and appropriate technology protection increased, the need to shorten the time required for administrative procedures related to the designation and removal of national core technologies was raised. Therefore, this study studied the criteria for identifying patents related to national core technologies. For AMOLED, a national core technology in the display field, LDA topic modeling was applied to related news and papers to derive important technology and its trends, and mapped to AMOLED advanced technology processes under Article 5 of the Industrial Development Act to prepare criteria for discrimination. Since then, objective verification has been conducted through AMOLED national core technology patents already known. Through this study, patents related to AMOLED national core technologies can be identified, which can shorten the time for related administrative procedures.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.4
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• pp.538-544
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• 2021

Technology readiness assessment is a procedure for managing defense project risk factors based on the preemptive identification of technical risks. Under current regulations, technology readiness is determined based on considerations of the ratings of factors itemized on a checklist, whether unsatisfied factors have a fatal impact on the project, and whether countermeasures for unsatisfied factors have been established. However, objective criteria for assessing the impact of unsatisfied factors have not been presented, and thus, at present, the results of technology readiness level determinations are largely subjective. In addition, the importance of questions on the checklist is dependent on individual project characteristics and this is not considered during the assessment process. In this paper, we propose an improved technology readiness assessment procedure that considers the characteristics of each project. Using the proposed procedure, we quantitatively determined the importance of each checklist item using a weighting method. We found the devised procedure improved the reliability and objectivity of technology readiness assessment results. A case analysis of a complex weapons system is presented to demonstrate these improvements.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.5
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• pp.892-902
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• 2015

Agri-food ICT(Information and Communications Technologies) convergence has been raised as an important issue for agricultural industry competence. In this situation, this study is to enhance agricultural competitiveness and seek to development plan for agricultural corporation by diagnosing informatization level. For this purpose, this study conducted survey on informatization level of 3,019 agricultural corporations and calculated level score. And result is compared with SMEs(Small and Medium Enterprise) informatization survey, including manufacturing and service industries, conducted by Korea Technology & Information Promotion Agency for SMEs in recent agricultural corporations' growing with automation of agricultural production and improving service to customer satisfaction. Evaluation system is established to calculate informatization level score and AHP(Analytic Hierarchy Process) method was used by the experts to investigate weighting of assessment area, assessment indicators, assessment items. As a result, agricultural corporation informatization level score was 40.16 points which is lower than the benefitted organization of agri-food IT convergence modeling(43.44 points). By assessment area, the informatization level of promotional environment area was low and investment and training items were analyzed low especially so need to improve urgently. In the analysis result by organization type, agricultural company corporation's informatization level was higher than the agricultural association corporation and 'Processing and distribution' was higher than others by business type. Informatization level of agricultural corporation is 80 percent of 2013 SMEs' level(50.18 points) and 59.4 percent of a large corporation(67.64 points). In particular, big difference is occurred in investment feasibility analysis, informatization investment and education which will be need to improve.

• The Journal of the Korea institute of electronic communication sciences
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• v.19 no.1
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• pp.317-326
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• 2024

Biometric recognition is a technology that determines whether a person is identified by extracting information on a person's biometric and behavioral characteristics with a specific device. Cyber threats such as forgery, duplication, and hacking of biometric characteristics are increasing in the field of biometrics. In response, the security system is strengthened and complex, and it is becoming difficult for individuals to use. To this end, multiple biometric models are being studied. Existing studies have suggested feature fusion methods, but comparisons between feature fusion methods are insufficient. Therefore, in this paper, we compared and evaluated the fusion method of multiple biometric models using fingerprint, face, and iris images. VGG-16, ResNet-50, EfficientNet-B1, EfficientNet-B4, EfficientNet-B7, and Inception-v3 were used for feature extraction, and the fusion methods of 'Sensor-Level', 'Feature-Level', 'Score-Level', and 'Rank-Level' were compared and evaluated for feature fusion. As a result of the comparative evaluation, the EfficientNet-B7 model showed 98.51% accuracy and high stability in the 'Feature-Level' fusion method. However, because the EfficietnNet-B7 model is large in size, model lightweight studies are needed for biocharacteristic fusion.