• Title/Summary/Keyword: technology level evaluation

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Essential Guidelines for Manufacturing and Application of Organoids

  • Sun-Ju Ahn;Sungin Lee;Dayeon Kwon;Sejeong Oh;Chihye Park;Sooyeon Jeon;Jin Hee Lee;Tae Sung Kim;Il Ung Oh
    • International Journal of Stem Cells
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    • v.17 no.2
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    • pp.102-112
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    • 2024
  • An organoid is a self-organized three-dimensional structure derived from stem cells that mimics the structure, cell composition, and functional characteristics of specific organs and tissues and is used for evaluating the safety and effectiveness of drugs and the toxicity of industrial chemicals. Organoid technology is a new methodology that could replace testing on animals testing and accelerate development of precision and regenerative medicine. However, large variations in production can occur between laboratories with low reproducibility of the production process and no internationally agreed standards for quality evaluation factors at endpoints. To overcome these barriers that hinder the regulatory acceptance and commercialization of organoids, Korea established the Organoid Standards Initiative in September 2023 with various stakeholders, including industry, academia, regulatory agencies, and standard development experts, through public and private partnerships. This developed general guidelines for organoid manufacturing and quality evaluation and for quality evaluation guidelines for organoid-specific manufacturing for the liver, intestines, and heart through extensive evidence analysis and consensus among experts. This report is based on the common standard guideline v1.0, which is a general organoid manufacturing and quality evaluation to promote the practical use of organoids. This guideline does not focus on specific organoids or specific contexts of use but provides guidance to organoid makers and users on materials, procedures, and essential quality assessment methods at end points that are essential for organoid production applicable at the current technology level.

The Development of a Program Outcomes Assessment System for Utilization of Information and Communication Technology and the Latest Healthcare Technology in Nursing Education (정보통신과 최신 보건의료기술 활용에 관한 간호교육 프로그램 학습성과 평가체계 개발)

  • Jeong-Mi Jeong;Mi-Ra Nam
    • Journal of the Health Care and Life Science
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    • v.11 no.2
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    • pp.289-302
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    • 2023
  • This study is a methodological research aimed at developing a program outcome assessment system for 'Utilization of Information and Communication Technology and the Latest Healthcare Technology' as required for nursing education accreditation. To ensure the theoretical validity of the assessment system, Kim's evaluation model (2009) and Zimmaro's rubric development stages (2004) were applied. The program outcome assessment system for information and communication and healthcare technology was developed, encompassing performance criteria, performance level, achievement goals, curriculum, evaluation methods, criteria, and the Close-the-Loop. The resulting assessment system is anticipated to be effectively utilized in nursing education, demonstrating broad applicability. This study is significant in providing specific directions for the development of program outcome assessment systems in undergraduate nursing programs. Further research is expected to evaluate and analyze program outcomes based on the applied assessment system.

Feasibility Study on the Methodology of Test and Evaluation for UAV Positioning (무인항공기 위치정확도 시험평가 기법 연구)

  • Ju, Yo-han;Moon, Kyung-kwan;Kang, Bong-seok;Jeong, Jae-won;Son, Han-gi;Cho, Jeong-hyun
    • Journal of Advanced Navigation Technology
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    • v.22 no.6
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    • pp.530-536
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    • 2018
  • Recently, many studies for interoperability of UAV in the NAS has been performed since the application range and demand of UAV are continuously increased. For the interoperation of UAV in the NAS, technical standards and certification system for UAV which is equivalent to the commercial aircraft are required and test and evaluation methodology must be presented by standards. In this paper, qualification test and evaluation methodology aboutfor the UAV navigation system is proposed. For the research, the mission profile and operation environment of UAV were analyzed. Thereafter the test criteria were derived and the test methodology were established. Finally, the simulation and demonstration using test-bed UAV were performed. As a result of the test, it was confirmed that the navigation system of test UAV has a position accuracy about 1.4 meters at 95% confidence level in the entire flight stage.

The Impact of Service Level Management(SLM) Process Maturity on Information Systems Success in Total Outsourcing: An Analytical Case Study (토털 아웃소싱 환경 하에서 IT서비스 수준관리(Service Level Management) 프로세스 성숙도가 정보시스템 성공에 미치는 영향에 관한 분석적 사례연구)

  • Cho, Geun Su;An, Joon Mo;Min, Hyoung Jin
    • Asia pacific journal of information systems
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    • v.23 no.2
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    • pp.21-39
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    • 2013
  • As the utilization of information technology and the turbulence of technological change increase in organizations, the adoption of IT outsourcing also grows to manage IT resource more effectively and efficiently. In this new way of IT management technique, service level management(SLM) process becomes critical to derive success from the outsourcing in the view of end users in organization. Even though much of the research on service level management or agreement have been done during last decades, the performance of the service level management process have not been evaluated in terms of final objectives of the management efforts or success from the view of end-users. This study explores the relationship between SLM maturity and IT outsourcing success from the users' point of view by a analytical case study in four client organizations under an IT outsourcing vendor, which is a member company of a major Korean conglomerate. For setting up a model for the analysis, previous researches on service level management process maturity and information systems success are reviewed. In particular, information systems success from users' point of view are reviewed based the DeLone and McLean's study, which is argued and accepted as a comprehensively tested model of information systems success currently. The model proposed in this study argues that SLM process maturity influences information systems success, which is evaluated in terms of information quality, systems quality, service quality, and net effect proposed by DeLone and McLean. SLM process maturity can be measured in planning process, implementation process and operation and evaluation process. Instruments for measuring the factors in the proposed constructs of information systems success and SL management process maturity were collected from previous researches and evaluated for securing reliability and validity, utilizing appropriate statistical methods and pilot tests before exploring the case study. Four cases from four different companies under one vendor company were utilized for the analysis. All of the cases had been contracted in SLA(Service Level Agreement) and had implemented ITIL(IT Infrastructure Library), Six Sigma and BSC(Balanced Scored Card) methods since last several years, which means that all the client organizations pursued concerted efforts to acquire quality services from IT outsourcing from the organization and users' point of view. For comparing the differences among the four organizations in IT out-sourcing sucess, T-test and non-parametric analysis have been applied on the data set collected from the organization using survey instruments. The process maturities of planning and implementation phases of SLM are found not to influence on any dimensions of information systems success from users' point of view. It was found that the SLM maturity in the phase of operations and evaluation could influence systems quality only from users' view. This result seems to be quite against the arguments in IT outsourcing practices in the fields, which emphasize usually the importance of planning and implementation processes upfront in IT outsourcing projects. According to after-the-fact observation by an expert in an organization participating in the study, their needs and motivations for outsourcing contracts had been quite familiar already to the vendors as long-term partners under a same conglomerate, so that the maturity in the phases of planning and implementation seems not to be differentiating factors for the success of IT outsourcing. This study will be the foundation for the future research in the area of IT outsourcing management and success, in particular in the service level management. And also, it could guide managers in practice in IT outsourcing management to focus on service level management process in operation and evaluation stage especially for long-term outsourcing contracts under very unique context like Korean IT outsourcing projects. This study has some limitations in generalization because the sample size is small and the context itself is confined in an unique environment. For future exploration, survey based research could be designed and implemented.

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Slope Revegetation by Seeding works and Resent Nature Restoration in Japan (일본에 있어서의 파종공에 의한 법면녹화와 자연회복녹화)

  • Hiroshi, Yoshida;Koh, Jeung-Hyun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.8 no.2
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    • pp.83-89
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    • 2005
  • The historical changes of seeding work in Japan, the typical slope revegetation method, is possible to divide into five periods as follows; 1) The early period after creation(1927-1948) 2) The spreading period of modern revegetation work with manpower(1947-1958) 3) The spreading period of rapid revegetation technique using exotic grasses with machineries(1959-1985${\dots}$) 4) The spreading period of rapid reforestation technique by fast growing species mainly using leguminous shrub species(1986-1995${\dots}$) 5)The developing period of nature restoration technique using endemic arborous species(1996-) The evaluation basis of vegetated condition after slope seeding has been described to a official guide book, "The Standards of Slope Stabilizing Works" It was mainly revised three times after first edition in 1972, and also the point of evaluation basis changed from the vegetation coverage to the density of woody plant through the 3rd period and the 4th period Recently main purpose of slope seeding has been developing from the erosion protection to the nature restoration in the current of the 5th period, and "The tentative guidelines of slope nature restoration" was announced by The Slope Revegetation Section of Japanese Society of Revegetation Technology in 2004. It was proposed the planning techniques of using suitable seeds/plants based on the preservation level at the real each construction sites Consequently, at present the importance of advanced monitoring methods for vegetation maintenance and plant sociologic survey to evaluate the plant succession is increasing.

Development of a Numerical Algorithm for the Evaluation of Aerodynamic Driving Stability of a Vehicle (주행차량의 공기역학적 주행안전성 평가를 위한 알고리즘 개발연구)

  • Kim, Chul-Ho;Kim, Chang-Sun;Lee, Seung-Hyun
    • Transactions of the Korean Society of Automotive Engineers
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    • v.24 no.3
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    • pp.265-272
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    • 2016
  • The objective of vehicle aerodynamic design is on the fuel economy, reduction of the harmful emission, minimizing the vibration and noise and the driving stability of the vehicle. Especially for a sedan, the driving stability of the vehicle is the main concern of the aerodynamic design of the vehicle indeed. In this theoretical study, an evaluation algorithm of aerodynamic driving stability of a vehicle was made to estimate the dynamic stability of a vehicle at the given driving condition on a road. For the stability evaluation of a driving vehicle, CFD simulation was conducted to have the rolling, pitching and yawing moments of a model vehicle and compared the values of the moments to the resistance moments. From the case study, it is found that a model sedan running at 100 km/h in speed on a straight level road is stable under the side wind with 45 m/s in speed. But the different results may be obtained on the buses and trucks because those vehicles have the wide side area. From the case study of the model vehicle moving on 100 km/h speed with 15 m/s side wind is evaluated using the numerical algorithm drawn from the study, the value of yawing moment is $608.6N{\cdot}m$, rolling moment $-641N{\cdot}m$ and pitching moment $3.9N{\cdot}m$. These values are smaller than each value of rotational resistance moment the model vehicle has, and therefore, the model vehicle's driving stability is guaranteed when driving 100 km/h with 15 m/s side wind.

A Study on Improvement of Evaluation & Budget Coordination System for Effective NRDP (국가연구개발사업의 종합조정 제도개선방안에 관한 연구 -'04년도 종합조정을 중심으로-)

  • Jeong, Geun-Ha;Mun, Jin-Gyeong;Park, Mun-Su;Park, Byeong-Mu
    • Journal of Korea Technology Innovation Society
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    • v.8 no.1
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    • pp.183-208
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    • 2005
  • In recent years, national R&D programs tend to become larger and more complicated, which necessitates strengthening the overall coordination of national R&D programs at the inter-ministerial level from the program planning stage. This paper looks into the status and problems of Korea's national R&D programs and proffers ways to improve the current system It highlights the problems shown in the process of the 2004 overall coordination and their rectification. First, various ad-hoc private-led committee brought about inefficiency in decision making process. Therefore, it is necessary to streamline such committees and strengthen the function of the Office of Science and Technology Innovation, Second, in view of the implementation of the overall coordination system, it is necessary to identify the problems in full detail that were raised in the course of the previous year's overall coordination so that new projects can be allotted minimal grades and follow-up activities can be efficiently put into execution. Third, it is necessary to establish standing committees for constant review and efficient utilization that will be devoted to reviewing programs overlapped and their linkage. Fourth, priority of investment regarding the nation's strategic policy direction should be reflected. Fifth, given the lack of performance-based evaluation system, it is necessary to develop macro and micro evaluation indices in conjunction with enacting the tentatively named "Performance-based Law." The overall coordination system of national R&D programs should be supplemented and further developed in relation to the aforementioned problems and their rectification in order to enhance the expertise, fairness, and efficiency of the nation's R&D coordination system.

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Evaluation of the Korean National Food Composition Tables

  • Park, Hong-Ju;Chun, Hye-Kyung;Lee, Sung-Hyeon
    • Preventive Nutrition and Food Science
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    • v.9 no.2
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    • pp.190-193
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    • 2004
  • This review was conducted to evaluate the 'Korean Food Composition Table' and establish it as an internationally accepted database by examining its contents and evolution over time. The food composition table has been published by National Rural Living Science Institute, every 5 years, listing the nutrient content for each food, as both the raw agricultural product and processed foods, since the 1$^{st}$ edition in 1979 by RDA (Rural Development Administration). This is the basic data applied to the evaluation of the nutritional value of foods in Korea. The data is used as a useful tool in many fields, not only for the establishment of the National Food Supply Plan but also for nutritional research, the draft of National Food Policy, and in clinical and epidemiological research. The database is also utilized by food service providers and food processors, etc. Consumers and the international society have been interested in the quality and safety of foods and raw agricultural products. As these data expand in volume, the type of foods included in the composition table is expanded to cover new additions for the convenience of users of the 'Nutrient Data Base' as judged by the publishers. The form of these reports varies, according to the current information, from a simple booklet to CD-ROM and to the Web service. We expect to continue to make improvements in the National Standard Table for food composition through expanding both the quantity and quality of data in an orderly manner. This effort can help food composition data to be comprehensively developed systematically and gradually at the national level.l.

Design of Hybrid V2X Communication Platform for Evaluation of Commercial Vehicle Autonomous Driving and Platooning (상용차 자율 군집 주행 평가를 위한 하이브리드 V2X 통신 플랫폼 설계)

  • Jin, Seong-keun;Jung, Han-gyun;Kwak, Jae-min
    • Journal of Advanced Navigation Technology
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    • v.24 no.6
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    • pp.521-526
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    • 2020
  • In this paper, we propose a design method and process for hybrid V2X communication platform that combines WAVE communication and LTE-V2X communication which are C-ITS communication protocols for vehicle environments and Legacy LTE communication which is a commercial mobile communication for evaluating the autonomous platooning platform of commercial vehicles. For a safe and efficient autonomous platooning platform, an low-latency communication function based on C-ITS communication is required, and to control it, commercial communication functions such as Legacy LTE, which can be connected at all times, are required. In order to evaluate such a system, the evaluation equipment must have the same level of communication performance or higher. The main design contents presented in this paper will be applied to the implementation of hybrid V2X terminals for functional evaluation.

Secondary Neutron Dose in Carbon-ion Radiotherapy: Investigations in QST-NIRS

  • Yonai, Shunsuke;Matsumoto, Shinnosuke
    • Journal of Radiation Protection and Research
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    • v.46 no.2
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    • pp.39-47
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    • 2021
  • Background: The National Institutes for Quantum and Radiological Science and Technology-National Institute of Radiological Sciences (QST-NIRS) has continuously investigated the undesired radiation exposure in ion beam radiotherapy mainly in carbon-ion radiotherapy (CIRT). This review introduces our investigations on the secondary neutron dose in CIRT with the broad and scanning beam methods. Materials and Methods: The neutron ambient dose equivalents in CIRT are evaluated based on rem meter (WENDI-II) measurements. The out-of-field organ doses assuming prostate cancer and pediatric brain tumor treatments are also evaluated through the Monte Carlo simulation. This evaluation of the out-of-field dose includes contributions from secondary neutrons and secondary charged particles. Results and Discussion: The measurements of the neutron ambient dose equivalents at a 90#x00B0; angle to the beam axis in CIRT with the broad beam method show that the neutron dose per treatment dose in CIRT is lower than that in proton radiotherapy (PRT). For the scanning beam with the energy scanning technique, the neutron dose per treatment dose in CIRT is lower than that in PRT. Moreover, the out-of-field organ doses in CIRT decreased with distance to the target and are less than the lower bound in intensity-modulated radiotherapy (IMRT) shown in AAPM TG-158 (American Association of Physicists in Medicine Task Group). Conclusion: The evaluation of the out-of-field doses is important from the viewpoint of secondary cancer risk after radiotherapy. Secondary neutrons are the major source in CIRT, especially in the distant area from the target volume. However, the dose level in CIRT is similar or lower than that in PRT and IMRT, even if the contributions from all radiation species are included in the evaluation.