• Title/Summary/Keyword: susceptibility effect

Search Result 665, Processing Time 0.032 seconds

Effect of Lead Concentration on Surface Oxide Formed on Alloy 600 in High Temperature and High Pressure Alkaline Solutions (고온, 고압 알칼리 수용액에서의 Alloy 600 산화막 특성에 미치는 납 농도 영향)

  • Kim, Dong-Jin;Kim, Hyun Wook;Moon, Byung Hak;Kim, Hong Pyo;Hwang, Seong Sik
    • Corrosion Science and Technology
    • /
    • v.11 no.3
    • /
    • pp.96-102
    • /
    • 2012
  • Outer diameter stress corrosion cracking (ODSCC) has occurred for Alloy 600 (Ni 75 wt%, Cr 15 wt%, Fe 10 wt%) as a heat exchanger tube of the steam generator (SG) in nuclear power plants (NPP) during long term operation. Among many causes for SCC, lead (Pb) is known to be one of the most deleterious species in the secondary system. In the present work, the oxide formed on Alloy 600 was characterized as a function of the PbO content in 0.1 M NaOH at $315^{\circ}C$ by using an electrochemical impedance spectroscopy (EIS), a transmission electron microscopy (TEM), equipped with an energy dispersive x-ray spectroscopy (EDS). The oxide property was analyzed in view of SCC susceptibility.

A Field Trial as Dry-cow Therapy Using Nophazin (norfloxacin mixed cephalexin) in Mastitis Control (건유기 유방염 치료제 Nophazin리 야외응용시험)

  • 손봉환;황현순;김종훈;최진영
    • Korean Journal of Veterinary Service
    • /
    • v.13 no.2
    • /
    • pp.130-140
    • /
    • 1990
  • A field test using Nophazin (drying off period therapeutics) was done from May, 1989 to October, 1989. 299 quarters of 75 cows from 28 herds were tested. The results were summarized as follows. 1. At the day 7 after parturition, CMT-was 81.60%, clots were removed perfectly, removal rate of hard, hot, pain was 99.6%, only one hard 0.35% was maintained. Recovery rate of general symptoms was 100%. 2. Recovery rate in Nophazin treatment was 100% in Micro-coccus SPP, Corynebacterium SPP, and unisolated, 97.06% in Enterobacterid SPP, 95.58% in Staphylococcus SPP, 91.67% in other Bacilli, 89.19% in Streptococcus SPP, Overall recovery rate was 95.32%, And fungi did not react. 3. The ratio of isolated microorganisms was Staphylococcus SPP 49.8%, Streptococcus SPP 16.3%, Enterobacteria SPP 15.0%, Micrococcus SPP 7.9% Corynebacterium SPP 4.4%, Pseudomonas SPP 2.6%, Bacilli 2.6% and Fungi 1.3%. 4. The range of sensitivity of each microorganism to therapeutics is as follow : Staphylococcus SPP 61.1∼94.7%, Streptococcus SPP 51.4∼91.9%, Micrococcus SPP 44.4∼94.4%, Corynebacterium SPP 70∼80%, Enterobacteria SPP 11.8∼88.2%, and other Gram negative bacilli 8.3∼83.3%. Overall sensitivity was in the range of 50.4∼92.0%, Microorganisms showed the highest sensitivity (80∼94.7%) to Nophazin. 5. New intramammary infection rate was 3.96% (9 strains) at paturition, 8.37% (19 strains) at the day 7 after paturition. Persistent organism wits 6.17% .(14 strains). 6. There was no side effect of Nophazin treatment.

  • PDF

Yeast Cell Wall Lytic Enzyme Produced by Dicyma sp. YCH-37 II. Effect of Culture Conditions and Pretreatment of Yeast on the Enzyme Activity (Dicyma sp. YCH-37이 생산하는 효모세포벽 용해효소 II. 효소활성에 미치는 기질 효모의 배양조건 및 전처리 효과)

  • Chung, Hee-Chul;Hahm, Byoung-Kwon;Yu, Ju-Hyun;Bai, Dong-Hoon
    • Korean Journal of Food Science and Technology
    • /
    • v.29 no.5
    • /
    • pp.1021-1027
    • /
    • 1997
  • We examined some properties of yeast cell wall lytic enzyme produced by Dicyma sp. YCH-37. Several metal ions, reducing reagents, and chemical modifiers have little effects on the lytic activity, except guanidine-HCl. Yeast cells of early log phase were more susceptible to the enzyme than those of stationary phase, and heat-treated cells were more easily lysed than intact living ones. Yeast cells pretreated with organic solvents such as butanol and acetone were more susceptible to the enzyme than intact living ones. Yeast cells cultured in Yeast extract-Malt extract medium containing 0.5 M ammonium sulfate were easily lysed by the lytic enzyme, and yeast cells cultured without shaking were more easily lysed by the enzyme than those with shaking. When SDS, ${\beta}-mercaptoethanol$, Triton X-100, sodium sulfite, and KCl were added to enzyme reaction mixture each, lysis of yeast cells was more effective.

  • PDF

A study on the Development of an electronic control unit using digital sensors for propulsion systems (디지털센서를 이용한 추진 시스템 전자 제어장치 연구)

  • Son, Jong-Dae;Kim, Jung-Hoe;Lee, Jae-Yun;Kim, Tae-Wan;Yoon, Soo-Hee;Lee, Yong-Hwan;Kwak, Geunn-Yeong;Chung, Soon-Bae
    • Proceedings of the Korean Society of Propulsion Engineers Conference
    • /
    • 2010.11a
    • /
    • pp.167-169
    • /
    • 2010
  • Electronic control units for propulsion systems are devices which compute control algorithm by processing the systems' internal sensor signals. Due to the effect of transmission between sensors and a control unit, previous analog systems have drawbacks of signal attenuation and susceptibility to noises. However, a digital sensor can be less influenced by the electrical cable line as it includes sensor, AMP, and AD converter in one module. In addition, it can reduce the process time for control algorithm because extra S/W filtering process is not needed. The current study shows how to process signals for an electronic control unit using digital sensors.

  • PDF

Realization of full magnetoelectric control at room temperature

  • Chun, Sae-Hwan;Chai, Yi-Sheng;Oh, Yoon-Seok;Kim, In-Gyu;Jeon, Byung-Gu;Kim, Han-Bit;Jeon, Byeong-Jo;Haam, S.Y.;Chung, Jae-Ho;Park, Jae-Hoon;Kim, Kee-Hoon
    • Proceedings of the Korean Magnestics Society Conference
    • /
    • 2011.12a
    • /
    • pp.101-101
    • /
    • 2011
  • The control of magnetization by an electric field at room temperature remains as one of great challenges in materials science. Multiferroics, in which magnetism and ferroelectricity coexist and couple to each other, could be the most plausible candidate to realize this long-sought capability. While recent intensive research on the multiferroics has made significant progress in sensitive, magnetic control of electric polarization, the electrical control of magnetization, the converse effect, has been observed only in a limited range far below room temperature. Here we demonstrate at room temperature the control of both electric polarization by a magnetic field and magnetization by an electric field in a multiferroic hexaferrite. The electric polarization rapidly increases in a magnetic field as low as 5 mT and the magnetoelectric susceptibility reaches up to 3200 ps/m, the highest value in single phase materials. The magnetization is also modulated up to 0.34 mB per formula unit in an electric field of 1.14 MV/m. Furthermore, this compound allows nonvolatile, magnetoelectric reading- and writing-operations entirely at room temperature. Four different magnetic/electric field writing conditions generate repeatable, distinct M versus E curves without dissipation, offering an unprecedented opportunity for a multi-bit memory or a spintronic device applications.

  • PDF

Effects of Sterilization for Quality Control on the Content of Paeonol in Moutan Radicies Bark (품질 보증을 위한 멸균법이 목단피의 패오놀 함량에 미치는 영향)

  • Lee, Yong-Soo;Shin, Woon-Seob;Cho, So-Yean;Ze, Keum-Ryon;Lee, Hyo-Min;Jeong, Choon-Sik
    • YAKHAK HOEJI
    • /
    • v.49 no.2
    • /
    • pp.180-184
    • /
    • 2005
  • The purpose of this study was to develop the best methods to sterilize Moutan Root Bark which is frequently used as a herbal medicine, and known to have high susceptibility to m icrobial contamination. We used dry heat, gamma irradiation and alcohol gas treatment for sterilization, and evaluated these methods in terms of the followings; I) the efficacy of sterilization, and ii) the chemical alteration of a major component of the harbal medicines. Treatment with dry heat effectively got rid of contaminated microorganisms, and did not significantly alter the content of paeonol. However it seriously changed the color and morphology which are an essential criterion to estimate a measure of quality of medicinal herbs. Treatment with gamma irradiation showed a strong sterilizing effect, and no alteration of the content of paeonol, color and morphology. Alcohol gas treatment resulted in similar effects as those in gamma irradiation. Collectively, these results suggest that appropriate sterilizing methods to guarantee the microbial quality of this herbal medicine may be those using gamma irradiation or alcohol gas.

Genetic Variations of ABCC2 Gene Associated with Adverse Drug Reactions to Valproic Acid in Korean Epileptic Patients

  • Yi, Ji Hyun;Cho, Yang-Je;Kim, Won-Joo;Lee, Min Goo;Lee, Ji Hyun
    • Genomics & Informatics
    • /
    • v.11 no.4
    • /
    • pp.254-262
    • /
    • 2013
  • The multidrug resistance protein 2 (MRP2, ABCC2) gene may determine individual susceptibility to adverse drug reactions (ADRs) in the central nervous system (CNS) by limiting brain access of antiepileptic drugs, especially valproic acid (VPA). Our objective was to investigate the effect of ABCC2 polymorphisms on ADRs caused by VPA in Korean epileptic patients. We examined the association of ABCC2 single-nucleotide polymorphisms and haplotype frequencies with VPA related to adverse reactions. In addition, the association of the polymorphisms with the risk of VPA related to adverse reactions was estimated by logistic regression analysis. A total of 41 (24.4%) patients had shown VPA-related adverse reactions in CNS, and the most frequent symptom was tremor (78.0%). The patients with CNS ADRs were more likely to have the G allele (79.3% vs. 62.7%, p=0.0057) and the GG genotype (61.0% vs. 39.7%, p=0.019) at the g.-1774delG locus. The frequency of the haplotype containing g.-1774Gdel was significantly lower in the patients with CNS ADRs than without CNS ADRs (15.8% vs. 32.3%, p=0.0039). Lastly, in the multivariate logistic regression analysis, the presence of the GG genotype at the g.-1774delG locus was identified as a stronger risk factor for VPA related to ADRs (odds ratio, 8.53; 95% confidence interval, 1.04 to 70.17). We demonstrated that ABCC2 polymorphisms may influence VPA-related ADRs. The results above suggest the possible usefulness of ABCC2 gene polymorphisms as a marker for predicting response to VPA-related ADRs.

Factors that Affect the Intention of Password Security Behavior (패스워드 보안행위의도에 영향을 미치는 요인)

  • Lee, Dong-Hee;Kim, Tae-Sung;Jun, Hyo-Jung
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.28 no.1
    • /
    • pp.187-198
    • /
    • 2018
  • Recently, financial transactions and electronic commerce in cyberspace are being performed more quickly and conveniently, with the development in diverse types of fintech and biometric authentication. But user authentication using passwords still occupies a big proportion even in these new services. therefore, safe creation and management of passwords is fundamental and indispensable to protect personal information and asset. This study examined the patterns of password usage by conducting a survey and analyzed factors influencing password security behavior intentions using the heath belief model. As a result, perceived susceptibility, perceived severity, perceived benefits, and perceived barriers significantly affected security behavior intentions, and especially, perceived severity had a moderating effect in other factors.

Effect of KGD1 Deletion on Cell Wall Biogenesis in Saccharomyces cerevisiae (Saccharomyces cerevisiae의 KGD1 유전자 결손이 세포벽 생합성에 미치는 영향)

  • Kim, Sung-Woo;Ahn, Ki-Woong;Park, Yun-Hee;Park, Hee-Moon
    • The Korean Journal of Mycology
    • /
    • v.38 no.1
    • /
    • pp.29-33
    • /
    • 2010
  • KGD1 gene was cloned by functional complementation of defects in $\beta$-1,3-glucan synthase activity of the previously isolated Saccharomyces cerevisiae mutant LP0353, which displays a number of cell wall defects at restrictive temperature. We performed the gene disruption experiment to characterize the function of KGD1 gene, which encodes $\beta$-ketoglutarate dehydrogenase, in cell wall biosynthesis. The disruption of KGD1 showed the decreased growth rate, the increase of chitin synthases activity, alterations in cell wall composition, and increase of susceptibility to cell wall inhibitors such as Calcofluor white and Nikkomycin Z. These results suggested that KGD1 might be involved in cell wall biogenesis, especially the biosynthesis of $\beta$-1,6-glucan and chitin in S. cerevisaie.

Iron Increases Susceptibilities of Pseudomonas aeruginosa to Ofloxacin by Increasing the Permeability

  • Kim, Sookyoung;Kim, Jinsook;Hyeran Nam;Yusun Jung;Lee, Yeohee
    • Journal of Microbiology
    • /
    • v.38 no.4
    • /
    • pp.265-269
    • /
    • 2000
  • Iron increased the susceptibilities of clinical isolates Pseudomonas aeruginosa to quinolones. In the presence of iron, increased susceptibilities to ofloxacin were observed in twenty-six out of thirty isolates and with no change in four isolates. In the case of norfloxacin, iran increased susceptibilities of twelve isolates but did not render any change in eighteen isolates. In the case of ciprofloxacin, iron decreased the MICs (Minimal Inhibitory Concentration) of twenty isolates, increased the MIC of one isolate, and did net change the MICs of nine isolates. To find out how iron increased susceptibility to ofloxacin, bacterial cells were grown in Muller Hinton (MH) media and succinate minimal media (SMM) to induce iran acquisition systems and the intracellular ofloxacin concentrations were assayed in the presence of iron. The addition of iron to the media decreased the MICs of cells whether they were grown in MH or SMM. Siderophores, carbonyl cyanide m-chlorophenylhydrazone (an inhibiter of proton motive force), and ouabain (an inhibitor of ATPase) did not decrease the effect of iron. Results suggested that the increase in the intracellular ofloxacin concentration by iron is accomplished not by decreasing the efflux but by increasing the of ofloxacin permeability.

  • PDF