• 한국보육지원학회지
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• 제12권4호
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• pp.111-130
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• 2016

This study examined the reliability and validity evidence of the Korean version of Wechsler Primary & Preschool Scale for Intelligence(K-WPPSI-IV), which was standardized recently. Following the stratified sampling for Korean population in terms of region and maternal education level, 1,700 children aged 2.6~7.7 years were recruited for Korean norm development. The split-half reliability (N=1,700) was high(Fisher's z(.75-.89)) and test-retest reliability(N=100) was satisfactory ranging from .95 to .68. The inter-rater reliability(N=110) was very high(.96-1.0). Discriminant and convergent validities were revealed by correlational patterns among subtests and indices. Future studies are needed to extend both reliability and validity of K-WPPSI-IV by collecting data with a various sample group and a variety of instruments.

• Ocean and Polar Research
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• 제26권1호
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• pp.65-75
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• 2004

In order to understand the water masses and their distribution in the eastern Yellow Sea from winter to spring, a cluster analysis was applied to the temperature and salinity data of Korea Oceanographic Data Center from 1970 to 1990. From December to April, Yellow Sea Cold Water (YSCW) dominates the eastern Yellow Sea, whereas Eastern Yellow Sea Mixed Water (MW) and Yellow Sea Warm Water (YSWW) are found in the southern part of the eastern Yellow Sea. MW appears at the frontal region around $34^{\circ}N$ between YSCW in the north and YSWW in the south. On the other hand, Tshushima Warm Water (TWW) is found around Jeju Island and the South Sea of Korea. These water masses are relatively well-mixed throughout the water column due to the winter monsoon. However, the water column begins to be stratified in spring due to increased solar heating, the diminishing winds and fresh water discharge, and the water masses in June may be separated into surface, intermediate and bottom layers of the water column. YSWW advances northwestward from December to February and retreats southeastward from February to April. This suggests a periodic movement of water masses in the southern part of the eastern Yellow Sea from winter to spring. YSWW may continue to move eastward with the prevailing eastward current to the South Sea from April to June. Also, the front relaxes in June, but the mixed water advances to the north, increasing salinity. The salinity is also higher in the nearshore region than offshore. This indicates an influx of oceanic water to the north in the nearshore region of the eastern Yellow Sea in spring in the form of mixed water.

• Journal of Advanced Marine Engineering and Technology
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• 제26권1호
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• pp.37-47
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• 2002

Recently gasoline direct injection method has been applied to gasoline engine to reduce fuel consumption rate by controlling fuel air mixture on lean condition by means of stratified charging, and to reduce simultaneously. Pollutant emissions especially NOx and CO by lowering the combustion temperature. But difficulty of controling local fuel air ratio at ignition area in flammability limit unavoidably appeared, because it is merely controlled by injection timing with spatial and temporal distribution of fuel mixture. In this study, the authors devised a uniquely shaped combustion chamber so called three-chamber GDI engine, intended to keep the more reliable fuel air ratio at ignition area. The combustion chamber is divided into three regions. The first region is in the rich combustion division, where the fuel is injected from the fuel injection valve and ignited by the spark plug. The second region is in the lean combustion division, where the combustion gas from the rich combustion division flows out and burns on lean condition. And the last region is in the main combustion division ie in the cylinder, where the gas from the above two combustion divisions mixed together and completes the combustion during expansion stroke. They found that the stable range of operation of three-chamber GDI engine on low-load condition exists in the lean area of average equivalence ratio. And they also found that the reformed engine reveals less specific fuel consumption and less pollutant emissions compared with conventional carburettor type gasoline engine.

• 한국해안해양공학회지
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• 제7권3호
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• pp.248-256
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• 1995

표층밀도분류에 대한 수치계산에서 문제로 되는 것은 자유수면의 처리, 레이놀즈응력/플럭스항, 특히 난류변동성분에 미치는 부력효과 등에 관련된 것이며, 이것에 대한 보다 집중적인 연구가 필요하다. 또한, 농도장이나 온도장에서의 난류변동성분을 측정하는 데 있어서의 어려움으로 인한 실험자료의 부족으로 수치 계산으로부터 얻어진 예측결과의 충분한 검증은 이루어지지 않고 있다. 본 연구에서는 2차원 표층밀도분류에 대한 유동특성을 조사하기 위하여 난류의 비등방성을 고려하여 난류응력을 직접 계산하는 대수응력모델을 적용하여 수치계산을 행하고, 그 결과를 실험결과와 비교ㆍ검토하였다. 검토한 결과 대수응력모델은 전 영역모델은 전 영역에서 2차원 표층밀도분류의 유동특성을 양호하게 재현하였으며, 특히 부력효과로 인한 성층화가 발생하는 부력 탁월영역에서 난류유동장의 흐름특성을 합리적으로 예측함을 입증하였다.

• Journal of the korean society of oceanography
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• 제32권3호
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• pp.93-102
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• 1997

Coastal circulations during the (surface condition of an) idealized cold-air outbreak are numerically investigated with two-dimensional, non-hydrostatic model in which a constant bottom-slope exists. The atmospheric forcing during a cold-air outbreak is incorporated as the surface cooling and the wind stress. When the offshore angle of the wind-stress vector, defined as the angle measured from the alongshore axis, is smaller than 45 degrees, a strong downwelling circulation develops near the coast. A sharp density front, which separates the vertically homogeneous region from the offshore stratified region, is formed near the coast and propagates offshore with time. Onshore side of the density front, small-scale circulation cells which are aligned in the direction perpendicular to the bottom begin to develop as the near-coast homogeneous region broadens. The surface cooling enhances greatly the development of the surface mixed layer by convective motions due to hydrostatic instability. The convective motions reach far below the hydrostatically unstable layer which is attached to the surface. The small-scale circulation cells are appreciably modified by the convetion cell and the density front develops far offshore compared to the case of no surface cooling. As to the effect of the bottom slope, the offshore distance of the density front increases (decreases) as the bottom slope decreases (increases), which results from the fact that the onshore volume-transport (Ekman transport) of the low-density upper seawater remains almost constant when the wind-stress is maintained constant. It is shown that the bottom slope is an essential factor for the formation of both the density front and the alongshore current when the surface cooling is the only forcing.

• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10675-10681
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• 2015

Background: The ataxia telangiectasia mutated (ATM) protein and p53 play key roles in sensing and repairing radiation-induced DNA double strand breaks (DSBs). Accumulating epidemiological evidence indicates that functional genetic variants in ATM and TP53 genes may have an impact on the risk of radiotherapy-induced side effects. Here we performed a meta-analysis to investigate the potential interaction between ATM Asp1853Asn and TP53 polymorphisms and risk of radiotherapy-induced adverse effects quantitatively. Materials and Methods: Relevant articles were retrieved from PubMed, ISI Web of Science and the China National Knowledge Infrastructure (CNKI) databases. Eligible studies were selected according to specific inclusion and exclusion criteria. Odds ratios (ORs) and 95% confidence intervals (CIs) were pooled to estimate the association between ATM Asp1853Asn and TP53 Arg72Pro polymorphisms and risk of radiotherapy adverse effects. All analyses were performed using the Stata software. Results: A total of twenty articles were included in the present analysis. In the overall analysis, no significant associations between ATM Asp1853Asn and TP53 Arg72Pro polymorphisms and the risk of radiotherapy adverse effects were found. We conducted subgroup analysis stratified by type of cancer, region and time of appearance of side effects subsequently. No significant association between ATM Asp1853Asn and risk of radiotherapy adverse effects was found in any subgroup analysis. For TP53 Arg72Pro, variant C allele was associated with decreased radiotherapy adverse effects risk among Asian cancer patients in the stratified analysis by region (OR=0.71, 95%CI: 0.54-0.93, p=0.012). No significant results were found in the subgroup analysis of tumor type and time of appearance of side effects. Conclusions: The TP53 Arg72Pro C allele might be a protective factor of radiotherapy-induced adverse effects among cancer patients from Asia. Further studies that take into consideration treatment-related factors and patient lifestyle including environmental exposures are warranted.

• 대한소아치과학회지
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• 제49권2호
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• pp.188-196
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• 2022

이 연구의 목적은 2002년부터 2015년까지 건강보험심사평가원 자료를 이용하여 대한민국 만 20세 미만 소아청소년의 치과를 주소로 응급실 방문 특성과 경향성에 대하여 조사하는 것이다. 연구 대상은 대한민국 전체 인구 중 2%인 약 100만 명을 무작위 표본 추출하여 만 20세 미만의 소아청소년들과 만 20세 이상의 성인들로 나누어 주상병, 성별, 지역, 소득수준 및 요양급여 비용에 대해 비교 분석하였다. 소아청소년에서 응급실 방문 비율은 비외상성 주상병보다 외상성 주상병에서 더 높게 관찰되었다. 비외상성 주상병의 비율은 소아청소년이 성인보다 낮았으며, 특히 입의 연조직염 및 농양(K12.2)과 치은염 및 치주질환(K05)에서 유의미한 차이를 보였다. 고소득 가구의 소아청소년이 저소득 가구의 소아청소년보다 응급실에 더 많이 내원하는 것으로 조사되었다. 소아청소년의 치과 응급 진료의 연도별 경향성은 표본 수가 적어 확인할 수 없었으나 소아청소년의 치과를 주소로 응급실에 내원하는 특성을 성인과 비교 및 분석이 가능하였다. 추후 연구에서 시간에 따른 유의미한 경향성을 파악하기 위해서는 표본 연구 자료가 아닌 맞춤형 자료를 이용한 연구가 필요할 것으로 보인다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권2호
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• pp.717-723
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• 2014

Background: This study was carried out to investigate the interaction of p53 codon 72 polymorphism, dietary and tobacco habits with reference to risk of stomach cancer in Mizoram, India. A total of 105 histologically confirmed stomach cancer cases and 210 age, sex and ethnicity matched healthy population controls were included in this study. Materials and Methods: The p53 codon 72 polymorphism was detected by PCR-RFLP and sequencing. H. pylori infection status was determined by ELISA. Information on various dietary and tobacco related habits was recorded with a standard questionnaire. Results: This study revealed that overall, the Pro/Pro genotype was significantly associated with a higher risk of stomach cancer (OR, 2.54; 95%CI, 1.01-6.40) as compared to the Arg/Arg genotype. In gender stratified analysis, the Pro/Pro genotype showed higher risk (OR, 7.50; 95%CI, 1.20-47.0) than the Arg/Arg genotype among females. Similarly, the Pro/Pro genotype demonstrated higher risk of stomach cancer (OR, 6.30; 95%CI, 1.41-28.2) among older people (>60 years). However, no such associations were observed in males and in individuals <60 years of age. Smoke dried fish and preserved meat (smoke dried/sun dried) consumers were at increased risk of stomach cancer (OR, 4.85; 95%CI, 1.91-12.3 and OR, 4.22; 95%CI, 1.46-12.2 respectively) as compared to non-consumers. Significant gene-environment interactions exist in terms of p53 codon 72 polymorphism and stomach cancer in Mizoram. Tobacco smokers with Pro/Pro and Arg/Pro genotypes were at higher risk of stomach cancer (OR, 16.2; 95%CI, 1.72-153.4 and OR, 9.45; 95%CI, 1.09-81.7 respectively) than the non-smokers Arg/Arg genotype carriers. The combination of tuibur user and Arg/Pro genotype also demonstrated an elevated risk association (OR, 4.76; 95%CI, 1.40-16.21). Conclusions: In conclusion, this study revealed that p53 codon 72 polymorphism and dietary and tobacco habit interactions influence stomach cancer development in Mizoram, India.

• Asian Pacific Journal of Cancer Prevention
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• 제17권12호
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• pp.5203-5209
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• 2016

Objective: To explore the prevalence of malignant tumors in the adult population through 2003-2014 in parts of the Aral Sea region: a zone of ecological disaster, a zone of ecological crisis and a zone of precritical conditions. Methods: The long-time average annual levels of cancer morbidity stratified by zones of the Aral Sea region and trends of long-time average annual incidence indicators of malignant tumors were identified. Leading cancer localizations in the adult population was established and associations between cancer incidence and environmental pollution were analyzed. In addition, associations between individual risk factors and cancer incidence in the adult population was established. Correlations between a hazard index and the cancer incidence in the adult population were calculated. Results: In all three Aral Sea regions, as well as in Zhanaarkinskii district, leading cancer in adult population was esophageal, stomach, tracheal, lung, hepatobiliary, and breast. Long-time average annual levels of cancer morbidity in adult population living in the Aral sea region is 1.5 times higher comparing to the control region. In particular, long-time average annual levels of cancer morbidity in adult population living in the zone of ecological disaster was 57.2% higher, in the zone of ecological crisis - 61.9% higher, and in the zone of precritical condition - 16.8% higher. Long-time average annual levels in the adult population of the Aral Sea region significantly exceeded control levels for brain and central nervous system cancer, cancer of bone and articular cartilage, and thyroid cancer. Conclusion: It has was established that the total cancer morbidity depended on the total hazard index associated with the inhalation of nickel and the combined cadmium intake (r=0.8).

• 한국지반공학회논문집
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• 제31권7호
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• pp.41-52
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• 2015

제주도 화산암은 여러 환경적인 요인으로 인하여 크기와 분포가 다양한 기공이 많은 다공성 구조를 보이고 있으며, 지질학적 그리고 역학적 특성 또한 지역마다 차이를 나타내고 있다. 뿐만 아니라, 제주도의 기반암은 여러 차례의 화산활동으로 인해 현무암층 사이에 연약층인 화산쇄설물 및 공동이 불규칙하게 발달된 층상구조로 이루어져 있다. 본 연구에서는 제주도 북서부 육 해상에서 채취한 현무암 암석에 대하여 다양한 물성 시험 및 일축압축강도 시험을 수행하고, 그 결과를 제주도 남동부 해상에서 채취한 현무암 암석의 물리적, 역학적 특성과 비교 분석하였다. 그 결과 제주도 북서부 육 해상에서 채취한 현무암 암석의 물리, 역학적 특성은 제주도 남동부 해상에서 채취한 현무암 암석과 유사한 관계에 있음을 확인할 수 있었으며, 물리적 특성과 역학적 특성의 상관관계로부터 대략적인 설계정수를 추정할 수 있었다.