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Immunohistochemical and serological observations on Neospora caninum infection in Korean indigenous cattle and calves of abnormal deliveries (한우 및 이상산 송아지의 Neospora caninum의 감염에 대한 면역조직화학적 및 혈청학적 관찰)

  • 손성봉;정원일;정규식;이차수
    • Korean Journal of Veterinary Service
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    • v.27 no.1
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    • pp.53-62
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    • 2004
  • The present study was carried out to investigate the prevalence of Neospora caninum infection in Korean indigenous cattle and calves of abnormal deliveries and focus on correlation between malformation and N caninum infection. To determine the prevalence of antibodies to N caninum, sera of 473 Korean indigenous cattle from slaughter house were tested for N caninum antibodies using indirect fluorescence assay. Of the 473 cattle sera, 9.5% (45/473) showed positive against N caninum. Regional seropositive rates of the samples were 16.7% (5/85), 11.0% (11/100), 8.8% (21/240) and 5.9% (5/85) at Kyonggi, Gyeongbuk, Daegu and Kyongnam province, respectively. In female, seropositive rates were 17.5% (25/143) and 6.1% (20/330) in male. During the period from march 2000 to August 2001, 55 abnormal deliveries of Korean indigenous cattle including abortion, stillbirth and congenital malformation were examined by histopathological, immunohistochemical and serological methods for evidence of N caninum infection. Of the 55 abnormal deliveries, only 5 calves showed positive reaction against N caninum in serological test. In microscopical observation, gliosis and nonsuppurative myositis were observed. However, Neospora-like organisms were not detected by either periodic acid-schiff (PAS) reaction or immunohistochemical technique. Taken together all these data, this study indicate that N caninum infection was widespread in breeding farms of Korean native cattle, but correlation between malformation and N caninum infection was not recognized.

$Ureaplasma$ infections in pre-term infants: Recent information regarding the role of $Ureaplasma$ species as neonatal pathogens

  • Sung, Tae-Jung
    • Clinical and Experimental Pediatrics
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    • v.53 no.12
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    • pp.989-993
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    • 2010
  • Although numerous clinical observational studies have been conducted over a period of over 30 years, the clinical significance of $Ureaplasma$ infection is still under debate. The $Ureaplasma$ speices. is a commensal in the female genital tract and considered to have of low virulence; however, $Ureaplasma$ colonization has been associated with infertility, stillbirth, preterm delivery, histologic chorioamnionitis, and neonatal morbidities, including congenital pneumonia, meningitis, bronchopulmonary dysplasia, and perinatal death. Recently, $Ureaplasma$ was subdivided into 2 separate species and 14 serovars. $Ureaplasma$ $parvum$ is known as biovar 1 and contains serovars 1, 3, 6, and 14, and $Ureaplasma$ $urealyticum$ (biovar 2) contains the remaining serovars (2, 4, 5, and 7-13). The existence of differences in pathogenicities of these 14 serovars and 2 biovars is controversial. Although macrolides are the only antimicrobial agents currently available for use in neonatal ureaplasmal infections, in the current clinical field, it is difficult to make decisions regarding which antibiotics should be used. Future investigations involving large, multicenter, randomized, controlled studies are needed before proper recommendations can be made for clinical practice.

Study on the Reproductive Performance of Dairy Cattle at Alpine Area in Kanweon-Do (강원도 고지 사육 유우의 번식실태에 관한 조사)

  • 이상영;양부근;김정익
    • Korean Journal of Animal Reproduction
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    • v.17 no.1
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    • pp.27-34
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    • 1993
  • The present study was conducted to examine the reproductive performance of dairy cow at alpine area. 1,515 dairy cows were managemented at above 800m of sea level around the Dea-Gwan Ryeong in Kangweon-Do. The results at this study were as follows ; 1. The average first estrus was 105.0 days after pastruation. 2. The highest percentage ofpregnancy(26.4%) and parturation(27.6%) were obtained at September to November and June to August, respectively. 3. The rate of pregnancy was 61.0%. Pregnancy rates according to insemination times of 1, 2 and 3 were 60.8, 23.5 and 9.8%, respectively and insemination time per pregnancy was 1.64. 4. Ages of first inseminatin, pregnancy and parturition of heifer were 17.9, 18.6 and 27.7 months, respectively. 5. Time of postpartum pregnancy was 133.0 days after parturition, and pregnancy period and calving interval were 279.6 and 410.3 days, respectively. 6. Six ratio of offspring was 52.1% of female versus 47.9% of male, and the proportion of twins was 0.65%. 7. The proportions of normal parturition, stillbirth and abortion were 91.9, 2.2 and 5.9%, respectively.

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A Case of Congenital Toxoplasmosis with Chorioretinitis Diagnosed by an Examination for Retinopathy of Prematurity (미숙아 망막증 검사 중 맥락망막염으로 진단된 선천성 톡소포자충증 1례)

  • Cho, Kyoung Soon;Kim, Sang Eun;Kim, Jong-Hyun;Oh, Jin Hee;Koh, Dae Kyun
    • Pediatric Infection and Vaccine
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    • v.13 no.2
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    • pp.196-200
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    • 2006
  • Congenital toxoplasmosis is caused by vertical transmission of Toxoplasma gondii from mother during pregnancy. The broad clinical spectrum of congenital toxoplasmosis ranges from stillbirth or death shortly after birth to survival with either cerebral damage or mild or subclinical disease, consisting usually of ocular involvement. The authors experienced a case of congenital toxoplasmosis in prematurity baby whose mother had lived recently in Africa. The diagnosis of congenital toxoplasmosis was confirmed on the basis of clinical finding of chorioretinitis and positive serologic test for toxoplasma IgM antibody.

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Studies on the Farrowing Inducction of Sow with Prostaglandin $F_2\alpha$ II. Health and Growth of Piglets Artificially borne by the Prostaglandin F2$\alpha$ Administration (Prostaglandin $F_2\alpha$ 투여에 의한 돼지의 분만유기에 관한 연구 II. 유기분만자돈의 건강과 발육)

  • 연정웅;정길생
    • Korean Journal of Animal Reproduction
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    • v.3 no.2
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    • pp.50-56
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    • 1979
  • This experiment was conducted to clarity the possibility of practical use of farrowing inductionin sow by the administration of prostaglandin F2$\alpha$. For this experiment, total 320 heads of pregnant sow and its piglets were used. The reproductive characteristics of artificially farrowed sow and, health and growth state of piglets were estimated. The results obtained in this experiment were summarized as following: 1. No significant difference were observed between naturally and artifically farrowed sow in several aspects such as the rate of dystocia, length of farrowing, farrowing intervals from piglet to piglet. 2. significant (P<0.05) differences were observed between naturally and artificially farrowed sow in intervals from weaning to estrus. However, there were no significant differences among those of 5, 7.5 and 10mg treated group. 3. There were no differences in number of stillbirth, immature birth and alive piglets at 3 weeks age per litter were observed. 4. Similar birth weight, weaning weight, daily gain and rearing rate of piglets were obtained from both naturally and artificially farrowing.

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Arsenic Toxicity in Male Reproduction and Development

  • Kim, Yoon-Jae;Kim, Jong-Min
    • Development and Reproduction
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    • v.19 no.4
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    • pp.167-180
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    • 2015
  • Arsenic is a toxic metalloid that exists ubiquitously in the environment, and affects global health problems due to its carcinogenicity. In most populations, the main source of arsenic exposure is the drinking water. In drinking water, chronic exposure to arsenic is associated with increased risks of various cancers including those of skin, lung, bladder, and liver, as well as numerous other non-cancer diseases including gastrointestinal and cardiovascular diseases, diabetes, and neurologic and cognitive problems. Recent emerging evidences suggest that arsenic exposure affects the reproductive and developmental toxicity. Prenatal exposure to inorganic arsenic causes adverse pregnancy outcomes and children's health problems. Some epidemiological studies have reported that arsenic exposure induces premature delivery, spontaneous abortion, and stillbirth. In animal studies, inorganic arsenic also causes fetal malformation, growth retardation, and fetal death. These toxic effects depend on dose, route and gestation periods of arsenic exposure. In males, inorganic arsenic causes reproductive dysfunctions including reductions of the testis weights, accessory sex organs weights, and epididymal sperm counts. In addition, inorganic arsenic exposure also induces alterations of spermatogenesis, reductions of testosterone and gonadotrophins, and disruptions of steroidogenesis. However, the reproductive and developmental problems following arsenic exposure are poorly understood, and the molecular mechanism of arsenic-induced reproductive toxicity remains unclear. Thus, we further investigated several possible mechanisms underlying arsenic-induced reproductive toxicity.

A Study on the Causes of Reproductive Disorders of Dairy Cattle introduced in Cheju-do II. The Investigation of Reproductive Disorders (제주도입 유우의 번식장애 원인에 관한 연구 II. 제주도입 유우의 번식장애 조사)

  • 김중규;양기천;강민수;김철균;장덕지;백윤기
    • Korean Journal of Animal Reproduction
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    • v.10 no.1
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    • pp.66-70
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    • 1986
  • The findings of a study on reproductive disorders and their causes with 685 dairty cows raised on dairy farms located in Cheju city, Jochun, Hallim and Sung-up are summarized as follows; 1. Among a total 685 dairy cows, 149 heads were identified as having reproductive disorders. They were subdivided into 26 genital organ diseases (3.8%), 53 delivery abnormalities (7.7%), 17 stagnation of after-birth (2.5%), 23 long period nonestrus (3.4%) and 30 repeat breeders (4.4%). Also, the regional incidence of those disorders was recorded as high as 30.8-31.5% in Jochun and Cheju city, and as low as 12.6-16.6% in Sung-up and Hallim districts. 2. The regional incidence of delivery abnormalities was estimated as high as 10.7% in the Cheju city area, and gradually reduced to 8.8% in Jochun, 6.8% in Sung-up and 6.2% in the Hallim district. Abortion (3.1%), stillbirth (2.0%) and 욘새챰 (2.6%) were included in the delivery abnormalities.

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A Case of Antiphospholipid Syndrome Associated with Protein C Deficiency (C단백질 부족증과 관련된 항인지질 증후군 1례)

  • Nam, Y.S.;Han, S.Y.;Choi, D.H.;Yoon, T.K.;Cha, K.Y.
    • Clinical and Experimental Reproductive Medicine
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    • v.26 no.1
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    • pp.123-126
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    • 1999
  • A successful outcome of pregnancy requires an efficient uteroplacental vascular system. Since this system may be compromised by disorders of haemostasis associated with a prothrombotic state, maternal thrombophilia might be a risk factor for fetal loss. Hereditary deficiencies of the naturally occuring anticoagulants are well recognized conditions predisposing to recurrent venous thromboembolism. Since thrombotic phenomena have been implied as a cause of abortion and stillbirth, these deficiencies might increase the risk of fetal demise. We have experienced a case of antiphospholipid syndrome associated with protein C deficiency in patient with recurrent spontaneous abortion. So we report this case with a brief review of literatures.

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Identification of Korean native cattle persistently infected with BVDV using Ear-notch method

  • Kim, Youngsik;Kim, Yongkwan;Lee, Sook-Young;Lee, Kyoung-Ki;Lee, Kyung-Hyun;Song, Jae-Chan;Oem, Jae-Ku
    • Korean Journal of Veterinary Service
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    • v.42 no.2
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    • pp.117-120
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    • 2019
  • Bovine viral diarrhea Virus (BVDV) infections cause respiratory, gastrointestinal, and reproductive problems, such as infertility, abortion, stillbirth, and sickly offspring. Many countries have reduced the economic damage through the application of different control programmes, and some have successfully eradicated BVD. Detection and elimination of cattle persistently infected (PI) with BVDV is important for BVD eradication because PI cattle are a main source of BVD transmission. In this study, the prevalence of Korean native cattle persistently infected (PI) with BVDV was investigated and determined in 49 farms with 3,050 cattle. The all samples were collected by ear notch sampling. Korean native cattle with initial positives on antigen-ELISA (Ag-ELISA) were sampled again after 3~4 weeks and cattle with second positives in both Ag-ELISA and immunohistochemistry (IHC) were identified as PI cattle. Among the 49 farms, 14 (28.6%) farms had at least more than one PI cow and 21 (0.69%) of 3,050 cattle were determined as PI cattle. As a result of this work, it is suggested that national BVD eradication program is required to reduce economic losses by BVDV infection in Korean cattle industries.

Traumatic perinatal events and educational needs of labor and delivery room nurses in Korea: a cross-sectional survey

  • Nagyeong Lee;Gunjeong Lee
    • Women's Health Nursing
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    • v.30 no.1
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    • pp.67-78
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    • 2024
  • Purpose: The present study investigated experiences of traumatic perinatal events, the provision of related education, and educational needs of nurses working in the labor and delivery room (LDR). Methods: Nurses working in the LDRs of six institutions and two nurse portal sites were invited to participate in the survey, delivered on paper or online. The data were collected from October 1 to November 25, 2022. Data from 129 nurses were analyzed using frequency, the chi-square test, the Fisher exact test, the t-test, and analysis of variance. Results: Virtually all participants (98.6%) reported having experienced at least one traumatic perinatal event (dystocia, postpartum hemorrhage, neonatal congenital anomalies, severe maternal or neonatal injury, stillbirth, and maternal or neonatal death) while working in the LDR. The most shocking traumatic perinatal event experienced was the maternal or neonatal death (40.3%), but 24.8% of participants did not recall ever receiving education on the topic. About 63% of participants experienced traumatic perinatal events within a year of working in the LDR. The average score for education needs regarding traumatic perinatal events was 3.67±0.37 out of 4, and participants preferred simulation education as the most effective educational method. Conclusion: Since most of the participants had experienced various traumatic perinatal events in the early stages of working in the LDR and expressed a high level of need for education on traumatic perinatal events, it is necessary to provide more effective stimulation education programs in the early period of work in the LDR.