• Title/Summary/Keyword: statistical data analysis

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Bioequivalence of MeloxifenTM Capsule to MobicTM Capsule(Meloxicam 7.5 mg) (모빅캡슐(멜록시캄 7.5mg)에 대한 멜록시펜캡슐의 생물학적 동등성)

  • Lee, Jin-Sung;Tak, Sung-Kwon;Seo, Ji-Hyung;Kang, Jong-Min;Ryu, Ju-Hee;Yim, Sung-Vin;Hong, Seung-Jae;Lee, Kyung-Tae
    • Journal of Pharmaceutical Investigation
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    • v.39 no.6
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    • pp.457-463
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    • 2009
  • The purpose of the present study was to evaluate the bioequivalence of meloxicam capsule, $Mobic^{TM}$ capsule( Boehringer Ingelheim Ltd., Korea) as a reference drug and $Meloxifen^{TM}$ capsule (Kukje Pharma Ind. Co., Ltd., Korea) as a test drug, according to the guidelines of Korea Food and Drug Administration(KFDA). Thirty two healthy male Korean volunteers received capsule containing meloxicam 7.5 mg in a $2{\times}2$ crossover study. There was a one-week above washout period between the doses. Plasma concentrations of meloxicam were monitored for over a period of 72 hr after administration by using a high performance liquid chromatography-tandem mass spectrometer(LC-MS/MS). $AUC_t$(the area under the plasma concentration-time curve from time zero to 72 hr), $C_{max}$(maximum plasma drug concentration) and $T_{max}$(time to reach $C_{max}$) were complied from the plasma concentration-time data. Analysis of variance(ANOVA) test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$ and $C_{max}$. The 90% confidence intervals of the $AUC_t$ ratio and the $C_{max}$ ratio for $Meloxifen^{TM}/Mobic^{TM}$ were log 0.8605-log 0.9847 and log 0.9765-log 1.1503, respectively. These values were within the acceptable bioequivalence intervals of log 0.80-log 1.25, recommended by KFDA. In all of these results, we concluded that $Meloxifen^{TM}$ capsule was bioequivalent to $Mobic^{TM}$ capsule, based on the rate and extent of absorption.

Research on 'What Causes Influence on the Inclination to Participation in Design-Talent Donation' : A Comparison between Prospective Designers and Professional Designers (디자이너의 사회적 위치에 따른 디자인 재능기부 참여의향과 영향요인 연구)

  • Kim, Kyung-Won
    • The Journal of the Korea Contents Association
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    • v.16 no.11
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    • pp.675-682
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    • 2016
  • Design-talent donation is a new form of social contribution activities using designers' professional skill and experience. The purpose of this study is to demonstrate which causes affect the inclination to participate in design-talent donation, taking into account that the research compared prospective designers and professional designers. When it comes to research method, this study classified the capabilities of designers with professional designers and prospective designer as potential talent donation provider. The research executed questionnaires of each factors and collected data were verified by using t-test analysis. Through the survey analysis to determine the factors affecting each group validated statistical difference between the two groups. The results showed that there is a significant difference in the impact factors between professional designers and prospective designers who involve in design-talent donation. The type of compensation could be expected to know that there is no significant correlation between the two groups. The meanings of this study are value addition criteria for the design output that provided from design talent donation should be clarified and ultimately is expected to specify the design talents donations range to meet the needs of designers as potential talent donation provider.

On the Sequences of Dialogue Acts and the Dialogue Flows-w.r.t. the appointment scheduling dialogues (대화행위의 연쇄관계와 대화흐름에 대하여 -[일정협의 대화] 중심으로)

  • 박혜은;이민행
    • Korean Journal of Cognitive Science
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    • v.10 no.2
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    • pp.27-34
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    • 1999
  • The main purpose of this paper is to propose a general dialogue flow in 'the a appointment scheduling dialogues' in German using the concept of dialogue acts. A basic a assumption of this research is that dialogue acts contribute to the improvement of a translation system. They might be very useful to solve the problems that syntactic and semantic module could not resolve using contextual knowledge. The classification of the dialogue acts was conducted as a work of VERBMOBIL project and was based on real dialogues transcribed by experts. The real dialogues were analyzed in terms of the dialogue acts. We empirically analyzed the sequences of the dialogue acts not only in a series of dialogue turns but also in one dialogue turn. We attempted to analyZe the sequences in one dialogue turn additionally because the dialogue data used in this research showed some difference from the ones in other existing researches. By examining the sequences in dialogue acts. we proposed the dialogue flowchart in 'the a appointment scheduling dialogues' 'Based on the statistical analysis of the sequences of the most frequent dialogue acts. the dialogue flowcharts seem to represent' the a appointment scheduling dialogues' in general. A further research is required on c classification of dialogue acts which was a base for the analysis of dialogues. In order to e extract the most generalized model. we did not subcategorize each dialogue acts and used a limited number of items of dialogue acts. However. generally defined dialogue acts need to be defined more concretely and new dialogue acts for specific situations should be a added.

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An indicator for managing the regional variations in approval rates of long-term care (LTC) service (지역별 장기요양 인정의 차이 관리지표 개발)

  • Han, Eun-Jeong;Lee, JungSuk;Park, Seyoung;Jang, Soomok;Jung, Inkyung
    • The Korean Journal of Applied Statistics
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    • v.30 no.3
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    • pp.391-401
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    • 2017
  • This study develops an indicator to manage regional variations of approval rates for long-term care (LTC) service. We used LTC insurance data for grade assessment that include 433,155 applicants from 227 LTC centers across Korea in 2015. The approval rate for each center was defined as the proportion of the numbers of approved applicants out of all applicants. We assumed that the approval rates depended on the characteristics of applicants. We estimated the 'standard' approval rates from a multiple linear regression analysis using the characteristics of applicants as independent variables. The difference between the observed and the standard rates was then defined as an indicator for deviation. A center having a large difference could be considered as a center with a potential error in grade assessment. We also examined if the characteristics of investigators affected the approval rates. We found that the socio-demographic characteristics of applicants and reapplication rate for LTC grade were independent factors affecting the approval rates. Centers having the management indicator values falling outside the middle 95% of the distribution were identified as centers with an error in grading. We expect that this study will contribute to enhancing reliability and equity in LTC grading.

The Study of Factors Related to Clinical Competency in Dental Hygienist (울산지역 치과위생사의 실무능력 관련요인 분석)

  • Lee, Ga-Ryoung
    • Journal of dental hygiene science
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    • v.5 no.4
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    • pp.155-163
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    • 2005
  • The purpose of this exploratory study was to assess work performance of dental hygienists and identify factors influencing their work performance. A questionnaire was administered to 87 dental hygienists working dental clinics based in Ulsan during the period from June 2005 through July 2005. A total of 77 questionnaires were collected and used for analysis. SPSS 11.5 program was employed for statistical analysis. All data were expressed in terms of numbers, percentage and mean score. The results of the study are summarized as follows: 1. There was a significantly positive correlation between age and the level of work performance in the Scientific competency group and Esthetical competency group. 2. Unmarried dental hygienists demonstrated better work performance than married dental hygienists in Scientific, Esthetical and Personal competency groups, showing a statistically significant difference. 3. By education level, those with junior college degree had better work performance than those who are attending or graduated from college in the four groups. By workplace, those who were working at non-general hospitals demonstrated a higher level of performance in the three groups except the Ethical group, but the difference was not statistically significant. 4. A significantly positive relationship was observed between monthly pay and work performance in the Scientific, Personal and Esthetical competency groups. 5. A positive relationship was observed between work experience and performance in the Scientific competency group. But there was no difference between work experience and performance in the other three groups. 6. By working environment, those who were working with assistant nurses showed a higher level of performance than those working without assistant nurses in the Scientific competency group, and the difference was statistically significant.

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The Assessment of Management Practices on Foodservice , Clinical Nutrition Service in Hospital Foodservice Operations (병원 급식소의 급식 및 임상영양 서비스 업무 실태 조사)

  • Hong, Wan-Su;Kim, Hye-Jin;Jang, Eun-Jae
    • Journal of the Korean Dietetic Association
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    • v.6 no.2
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    • pp.136-147
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    • 2000
  • The aim of this research was to examine the management practices related to foodservice.clinical nutrition service provided by hospital foodservice operations. A survey of 30 hospital food nutrition service departments was undertaken and detailed information was collected from each, including surveys of 176 dietitians and 30 foodservice managers. Statistical data analysis was completed using the SAS/win 6.11 package for descriptive analysis and t-test. The results of this study can be summarized as follows : Out of 30 hospitals, 73.3%(22) were directly operated and 26.7%(8) were under contract foodservice management. Licensed number of beds were 768.7, with an average length of 11.4 days. The general characteristics of the dietitians were that 49.4% were aged between 25-29, and 60.8% were ordinary dietitians. 76.7% had bachelor's degree, 15.9% with master's degree and 7.4% were college graduates. Most hospital dietitians had internship training and 35.2% took a training course of 6 to 12 months. The average space of kitchen was 452.52 $m^2$, with 133.63$m^2$ for modified diet space and 18.13$m^2$ for nutrition counselling room space. The total number of normal meals was 1,255.47, with 502.93 of modified meals. The average calorie of normal meals was 2,145.04kcal, with 91.9g of protein contained in normal meal. The total food waste was 351.40kg. An average monthly cost for disposing food waste was 745,171.67 won. 83.3% of the kitchens were on the 1st basement and only 66.7%(20) of 30 hospitals had its own nutrition counselling room. 80% used dishwashers and 66.7% had an exclusive elevator for delivering meals. 80.0% of hospitals used centralized delivery service. 90% had established an area for hygiene division, 70% used dry zone within the dishwashers for sterilization, 66.7% provided spoon and chopstick, and 100% used dish cover. As means of food waste treatment, most hospitals(56.7%) used animal feed by contracters, followed by means of collection by contracters(30%) and in-house high speed fermentation machines(13.3%). It was found that only 33.3% hospitals regularly checked temperatures of the meals given to patients. Total productivity index was 3.72(meals/hour) in average, with an average productivity index for normal diet of 5.41. Average productivity index for modified diet was 4.62. Productivity indices for patient meals and clinical nutrition were 5.01(meals/hour) and 1.12(cases/hour) respectively and hospitals under self-operated foodservice management received higher points on clinical nutrition productivity index(P<0.01) than hospitals under contract foodservice management.

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A Study on the conflicts and satisfaction at the adults' places of work - family (성인의 직장-가정에서의 갈등과 만족도에 관한 연구)

  • Kim Heung-Gyu;Ka Yong-Hee
    • Journal of Families and Better Life
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    • v.23 no.1 s.73
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    • pp.85-98
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    • 2005
  • The purpose of this study is to make it clear that the influence the adults' work-family conflicts affect the family life satisfaction and the work life satisfaction of theirs, according to the personal backgrounds (sex, age, monthly income and whether the person works S days a week or not). The target group of this study is the selected 754 adults who are married with children that are in the employ of the various companies in Seoul and Incheon. The picked data are analyzed to factor analysis, frequencies, means, One-way ANOVA and multiple regression analysis etc..using Spss 11.5 version statistical program. Following is the result of the study: First, the level of work-family conflicts have been shown to be different as the result of verification by sex, age, monthly income and the type of duty(whether working 5days a week or not) out of the personal variables. The study shows that the level of work-family conflicts is different by the subordinate variables of work-family conflicts as the results of male and female comparison. And the older the age, the higher the level of family conflicts.'rho study shows that The level of the places of work conflicts is the highest in the 30s. The smaller monthly income, the higher the level of work-family conflicts. The study shows that the level of family conflicts is high in working 6days a week and the level of work conflicts is high in working 5days a week. Second, such factors for conflicts at home as family support, family expectations and financial difficulties affect the level of satisfaction at work, while such personal backgrounds as monthly pay, kinds of work and age level also play a role. At the same time, satisfaction in family life is influenced by such factors for conflicts at the places of work as support, involvement, expectations and work-overload at the places of work, with such personal backgrounds as monthly pay, age and sex compounding the impact. On the point how much conflicts at work and home affect the satisfaction at home, work and leisure, the study shows that family life does not have noticeable influence in the level of satisfaction at the places of work, whereas situations at the place of work have significant impact on the level of satisfaction in family lives. In other words, the lesser conflicts the work situations cause to family lives, the greater the level of satisfaction at work, home and at leisure.

Bond strength of veneer ceramic and zirconia cores with different surface modifications after microwave sintering

  • Saka, Muhammet;Yuzugullu, Bulem
    • The Journal of Advanced Prosthodontics
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    • v.5 no.4
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    • pp.485-493
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    • 2013
  • PURPOSE. To evaluate the effects of surface treatments on shear bond strength (SBS) between microwave and conventionally sintered zirconia core/veneers. MATERIALS AND METHODS. 96 disc shaped Noritake Alliance zirconia specimens were fabricated using YenaDent CAM unit and were divided in 2 groups with respect to microwave or conventional methods (n=48/group). Surface roughness (Ra) evaluation was made with a profilometer on randomly selected microwave (n=10) and conventionally sintered (n=10) cores. Specimens were then assessed into 4 subgroups according to surface treatments applied (n=12/group). Groups for microwave (M) and conventionally (C) sintered core specimens were as follows; $M_C$,$C_C$: untreated (control group), $M_1,C_1:Al_2O_3$ sandblasting, $M_2,C_2$:liner, $M_3,C_3:Al_2O_3$ sandblasting followed by liner. Veneer ceramic was fired on zirconia cores and specimens were thermocycled (6000 cycles between $5^{\circ}-55^{\circ}C$). All specimens were subjected to SBS test using a universal testing machine at 0.5 mm/min, failure were evaluated under an optical microscope. Data were statistically analyzed using Shapiro Wilk, Levene, Post-hoc Tukey HSD and Student's t tests, Two-Way-Variance- Analysis and One-Way-Variance-Analysis (${\alpha}$=.05). RESULTS. Conventionally sintered specimens ($1.06{\pm}0.32{\mu}m$) showed rougher surfaces compared to microwave sintered ones ($0.76{\pm}0.32{\mu}m$)(P=.046), however, no correlation was found between SBS and surface roughness (r=-0.109, P=.658). The statistical comparison of the shear bond strengths of $C_3$ and $C_1$ group (P=.015); $C_C$ and $M_C$ group (P=.004) and $C_3$ and $M_3$ group presented statistically higher (P=.005) values. While adhesive failure was not seen in any of the groups, cohesive and combined patterns were seen in all groups. CONCLUSION. Based on the results of this in-vitro study, $Al_2O_{3-}$ sandblasting followed by liner application on conventionally sintered zirconia cores may be preferred to enhance bond strength.

A Study of the Fluctuation factors and Model of Daily Visitors of National Park (국립공원의 이용자수 변동요인 및 추정모형에 관한 연구)

  • 안성노
    • Journal of the Korean Institute of Landscape Architecture
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    • v.17 no.2
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    • pp.27-39
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    • 1989
  • The purpose of this study is to prove the factors affecting the fluctuation of daily visitors in five mountainous national park(Kayasan, kyeryongsan, Naejangsan, Soraksan, Songnisan), and to analyze the relationship between these factors and daily visitors in Korea. "Three Factors and Nine Categories"(Aoki, K. & Aoki, Y. : 1974, 1979) has been applied to this study, and statistical analysis method was carried out by computer program SAS and SPSS. The number of daily visitors is calculated based on the data of "Daily entrance ticket sale report" by administration office in each national park. The scope of time period is during the last 5years(1982∼1986: 1825days) and the results were as follows: 1) There were significant differences in the number of daily visitors of each national park among months, days of a week and weather-the same as the previous study of urban park case. But it wold be better for their category classification to be adjusted according to the fluctuation pattern of each national park. 2) The peak of monthly visitors comes in May(Kayasan, Soraksan, Songnisan) or October(Kyeryongsan, Naejangsan). These months are specified as group tour season. On the basis of monthly fluctuation pattern, Each national park were classified into seasonal type, that is, kayasan, Soraksan were proved to be three-season type(Spring, Summer, Autumn), Songnisan to be two-season type(Spring, Autumn), and Naejangsan to be one-season type(Autumn). 3) The weekly pattern differs from three category (weekday, weekend, holiday: Eom, Choi 1986) in the case of urban park study. And there is no significant difference in daily fluctuation pattern by weather (fine, cloudy and rainy day), but significant difference between snowy and the others. This result is due to the characteristics of visitors, which is, the major visits of national park are planned in a advance of the tour, therefore it is difficult to change the plan by the weather. 4) the result of correlation analysis showed that the most influential factor on national park use in Kayasan, Naejangsan, Soraksan and Songnisan is ′Monthly characters (M)′, on the contrary ′Day of week(D)′ in Kyeryongsan only. From the result, The more parks are resource-based, the more ′Monthly characters′-factor is supposed to affect the number of daily visitors rather than ′Day of the week′-factor. This means that kayasan, naejangsan, Sorakson and Songnisan are classified into resource-based type, but on the other hand Kyeryongsan should be classified into intermediate type.

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Statistical Estimate and Prediction Values with Reference to Chronological Change of Body Height and Weight in Korean Youth (한국인 청소년 신장과 체중의 시대적 변천에 따른 통계학적 추정치에 관한 연구)

  • 강동석;성웅현;윤태영;최중명;박순영
    • Korean Journal of Health Education and Promotion
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    • v.13 no.2
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    • pp.130-166
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    • 1996
  • As compared with body height and body weight by ages and sexes, by means of the data reported under other researchers from 1967 to 1994 for 33 years, this study obtained the estimate value of body height and body weight by ages and sexes for the same period, and figured out prediction value of body height and body weight in the ages of between 6 and 14 from 1995 to 2000. These surveys and measurements took for one year from October 1st 1994 to September 30th. As shown in the 〈Table 1〉, in order to calculate the establishment, estimate value and prediction value of the chronological regression model of body height and body weight, by well-grounded 17 representative research papers, this research statistically tested propriety of liner regression model by the residual analysis in advance of being reconciled to simple liner regression model by the autonomous variable-year and the subordinate variable-body weight and measured prediction value, theoretical value from 1962 to 1994 by means of 2nd or 3rd polynomial regression model, with this redult did prediction value from 1995 to 2000. 1. Chronological Change of Body Height and Body Weight The analysis result from regression model of the chronological body height and body weight for the aged 6 - 16 in both sexes ranging from 1962 to 1994, corned from the 〈Table 2-20〉. On the one hand, the measurement value of respective researchers had a bit changes by ages with age growing, but the other hand, theoretical value, prediction value showed the regular increase by the stages and all values indicated a straight line on growth and development with age growing. That is, in case of the aged 6, males had 109.93cm in 1962 and females 108.93cm, but we found the increase that males had 1I8.0cm, females 1I3.9cm. In theoretical value, prediction value, males showed the increase from 109.88cm to 1I7.89cm and females from 109.27cm to 1I5.64cm respectively. There was the same inclination toward all ages. 2. Comparision to Measurement Value and Prediction Value of Body Height and Body Weight in 1994 As shown in the 〈Table 21〉, in case of body height, measurement value and prediction value of body height and body weight by ages and sexes almost showed the similiar inclination and poor grade, in case of body weight, prediction value in males had a bit low value by all ages, and prediction value in females had a high value in adolescence, to the contrary, a low value in adult. 3. Prediction Value of Body Height and Body Weight from 1995 to 2000 This research showed that body height and body weight remarkably increased in adolescence but slowly in adult. This study represented that Korean physique was on the increase and must be measured continually hereafter.

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