• Title/Summary/Keyword: smooth

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Some Properties of Product Smooth Fuzzy Topological Spaces

  • Park, Jin-Won
    • Journal of the Korean Institute of Intelligent Systems
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    • v.9 no.6
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    • pp.615-620
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    • 1999
  • We will investigate some properties of product smooth fuzzy topological spaces. We will show that a projection map in product smooth fuzzy topological spaces need not be a fuzzy open map. Furthermore a slice need not be homeomorphic to the coordinate spance which is parallel to it.

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Intuitionistic Smooth Bitopological Spaces and Continuity

  • Kim, Jin Tae;Lee, Seok Jong
    • International Journal of Fuzzy Logic and Intelligent Systems
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    • v.14 no.1
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    • pp.49-56
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    • 2014
  • In this paper, we introduce intuitionistic smooth bitopological spaces and the notions of intuitionistic fuzzy semiinterior and semiclosure. Based on these concepts, the characterizations for the intuitionistic fuzzy pairwise semicontinuous mappings are obtained.

Mechanosensitive Modulation of Receptor-Mediated Crossbridge Activation and Cytoskeletal Organization in Airway Smooth Muscle

  • Hai, Chi-Ming
    • Archives of Pharmacal Research
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    • v.23 no.6
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    • pp.535-547
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    • 2000
  • Recent findings indicate that mechanical strain (deformation) exerted by the extracellular matrix modulates activation of airway smooth muscle cells. Furthermore, cytoskeletal organization in airway smooth muscle appears to be dynamic, and subject to modulation by receptor activation and mechanical strain. Mechanosensitive modulation of crossbridge activation and cytoskeletal organization may represent intracellular feedback mechanisms that limit the shortening of airway smooth muscle during bronchoconstriction. Recent findings suggest that receptor-mediated signal transduction is the primary target of mechanosensitive modulation. Mechanical strain appears to regulate the number of functional G-proteins and/or phospholipase C enzymes in the cell membrane possibly by membrane trafficking and/or protein translocation. Dense plaques, membrane structures analogous to focal adhesions, appear to be the primary target of cytoskeletal regulation. Mechanical strain and receptor-binding appear to regulate the assembly and phosphorylation of dense plaque proteins in airway smooth muscle cells. Understanding these mechanisms may reveal new pharmacological targets for control1ing airway resistance in airway diseases.

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Influence of the Initiation Error of the Delay Detonator on the Rock Fracture Process in Smooth Blasting (SB발파에서 지발뇌관의 기폭초시오차가 암반파괴과정에 미치는 영향)

  • 조상호;양형식;금자승비고
    • Tunnel and Underground Space
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    • v.14 no.2
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    • pp.121-132
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    • 2004
  • Dynamic fracture processes of rock were analyzed to investigate the influence of the initiation error of the delay detonator in smooth blasting. The analysis models for the smooth blasting considered two blast geometries with three charge holes, and the simultaneous initiations without initiation error, with the initiation error of electronic delay detonator and with the initiation error of pyrotechnically delay detonator(DS detonator) were applied to the charge holes. In order to examine the effect of electronic and DS initiation detonator on the smooth blasting, the fracture process results were analyzed statistically.

Effects of Estradiol-17$\beta$ and Progesterone on the Spontaneous Motility of Pig Oviductal Isthmic Smooth Muscle in Follicular and Luteal Stages (난포기 및 황체기에 있어서 돼지 난관협부 평활근의 자율적 운동성에 대한 Estradiol-l7$\beta$및 Progesterone의 영향)

  • Lee Min-Gi;Son Dong-Soo;Lee Yeong-Lak;Nam Jeong-Woo;Kim Joo-Heon;Choe Sang-Yong
    • Journal of Veterinary Clinics
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    • v.8 no.2
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    • pp.191-195
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    • 1991
  • The effects of estradiol-17$\beta$ and progesterone on the spontaneous motility of pig oviductal isthmic smooth muscle were investigated. The motility of the Isolated smooth muscle was recorded by using physiological recording system. The results were summarized as follows; 1. The amplitude and frequency of spontaneous motility in pig isthmic smooth muscle were 0.251$\pm$0.023 g and 15.380$\pm$0.935/min in follicular stage, and 0.201$\pm$0.027g and 14.520$\pm$1.382/min in luteal stage. 2. The spontaneous motility of pig isthmic smooth muscle was excited by estradiol-17$\beta$ but was not by progesterone in follicular and luteal stage.

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Expression of Tumor Necrosis Factor (TNF)-z${\alpha}$ from Cells Undergoing Death by FADD

  • Kim, Koanhoi
    • Journal of Life Science
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    • v.12 no.2
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    • pp.57-60
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    • 2002
  • Apoptosis of vascular smooth muscle cell is observed in the vascular diseases such as atherosclerosis and restenosis. The death of vascular smooth muscle cells can be induced by cytokines and activation of Fas-pathways. It is widely accepted that apoptosis occurs without inflammation. There are, however, reports that apoptosis is not silent. Vascular smooth muscle cells dying by Fas-pathway secreted inflammatory cytokines including monocyte chemoattractant protein-1. This study have investigated whether apoptosis is associated with potent inflammatory cytokine tumor tumor necrosis factor (TNF)-${\alpha}$. The cells which undergo apoptosis by expressing FADD in the absence of tetracycline expressed and secreted TNF-${\alpha}$. When the level of TNF-${\alpha}$ transcript was investigated, dying smooth muscle cells exhibited transcriptional activation of TNF-${\alpha}$. The data indicate that dying vascular smooth muscle cells contribute to inflammation by expressing inflammatory cytokines. The present study suggests that apoptosis could not be silent in certain pathological situations.

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Smoothly Connected Path Generation and Time-Scheduling Method for Industrial Robot Applications (산업용로봇 작업을 위한 유연한 연결경로 생성과 시간계획)

  • Lee Won-Il;Ryu Seok-Chang;Cheong Joo-No
    • Journal of Institute of Control, Robotics and Systems
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    • v.12 no.7
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    • pp.671-678
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    • 2006
  • This article proposes a smooth path generation and time scheduling method for general tasks defined by non-smooth path segments in industrial robotic applications. This method utilizes a simple 3rd order polynomial function for smooth interpolation between non-smooth path segments, so that entire task can effectively maintain constant line speed of operation. A predictor-corrector type numerical mapping technique, which correlates time based speed profile to the smoothed path in Cartesian space, is also provided. Finally simulation results show the feasibility of the proposed algorithm.

Control of Parturition Time on Pig III. Effect of Histamine on Uterine smooth muscle motility (돼지 분만 시기에 조절에 관하여 III. 자궁 평활근의 운동성에 대한 Histamine의 영향)

  • 박상은;황보원;변유성;조광제
    • Korean Journal of Veterinary Service
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    • v.18 no.2
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    • pp.177-181
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    • 1995
  • The effects of histamine were investigated on the uterine smooth muscle motility in the pig. The results were summarized as fellows : 1. Histamine caused the contraction of the porcine uterine smooth muscle and the contractile responses increased between the concetration of histamine $10^{-8}$ and $10^{-5}$ M with a dose-dependent manner. 2. The contractile response Induced by histamine ($10^{-6}$ M) was completely blocked by pretrevatment with $H_1$-histaminergic receptor blocker, pyrilamine($10^{-6}$ M) 3. The contractile response induced by histamine($10^{-6}$ M) was increased by pretreatment with $H_2$-histaminergic receptor blocker, cimetidine($10^{-6}$ M) From these results, it was concluded that the effects of uterine smooth muscle by histamine were the contraction mediated by $H_1$-histaminergic receptor and the relaxation mediated by $H_2$-histaminergic receptor in pig.

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Testing for Lack of Fit via the Generalized Neyman Smooth Test

  • Lee, Geung-Hee
    • Journal of the Korean Statistical Society
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    • v.27 no.3
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    • pp.305-318
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    • 1998
  • Smoothing tests based on an L$_2$ error between a truncated courier series estimator and a true function have shown good powers for a wide class of alternatives, These tests have the same form of the Neyman smooth test whose performance depends on the selected order, a basis, the farm of estimators. We construct flexible data driven Neyman smooth tests by changing a basis, combining model selection criteria and different series estimators. A simulation study shows that the generalized Neyman smooth test with the best basis provides good power for a wider class of alternatives compared with other data driven Neyman smooth tests based on a fixed form of estimator, a fixed basis and a fixed criterion.

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