• Title/Summary/Keyword: slice

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Effect of Capsaicin on the Excitatory Amino Acids Neurotranmitters in Medullary Dorsal Horn (Capsaicin이 연수후각의 흥분성 아미노산 전달물질에 미치는 영향)

  • Kwon, Soo-Kyung;Yoon, Soo-Han;Lee, Jong-Heun
    • Restorative Dentistry and Endodontics
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    • v.19 no.2
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    • pp.621-632
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    • 1994
  • This experiment was performed to study the effect of capsaicin on the excitatory amino acids (EAAs) neurotransmitter in medullary dorsal horn and to clarify the relationship between substance P and excitatory amino acids. Horizontal slice of rat medullary dorsal horn was prepared and perfused with modified Krebs-Ringer solution in brain slice chamber. Release of EAAs was induced by veratrine and capsaicin were added to perfusion solution to observe the changes in EAA release. Capsaicin and ruthenium red, capsaicin antagonist, were also systemically injected with 50mg/kg in first day and 100mg/kg in second day for 2 days. Medulla oblongata containing the medullary dorsal horn was isolated, homogenized and centrifused. Spernatant was freeze-dried and EAA was determined by HPLC. Release of glutamate and aspartate was significantly increased by veratrine or capsaicin, but veratrine evoked release of EAAs was blocked by capsaicin in vitro, and injected ruthenium red did not have effect on the contents of EMs in vivo. Systemically injected capsaicin evoked the slight decrease in content of glutamate and aspartate in medullary dorsal horn and this effect of capsaicin was unaffected by ruthenium red.

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Co-registration of Multiple Postmortem Brain Slices to Corresponding MRIs Using Voxel Similarity Measures and Slice-to-Volume Transformation

  • Kim Tae-Seong
    • Journal of Biomedical Engineering Research
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    • v.26 no.4
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    • pp.231-241
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    • 2005
  • New methods to register multiple hemispheric slices of the postmortem brain to anatomically corresponding in-vivo MRI slices within a 3D volumetric MRI are presented. Gel-embedding and fiducial markers are used to reduce geometrical distortions in the postmortem brain volume. The registration algorithm relies on a recursive extraction of warped MRI slices from the reference MRI volume using a modified non-linear polynomial transformation until matching slices are found. Eight different voxel similarity measures are tested to get the best co-registration cost and the results show that combination of two different similarity measures shows the best performance. After validating the implementation and approach through simulation studies, the presented methods are applied to real data. The results demonstrate the feasibility and practicability of the presented co­registration methods, thus providing a means of MR signal analysis and histological examination of tissue lesions via co­registered images of postmortem brain slices and their corresponding MRI sections. With this approach, it is possible to investigate the pathology of a disease through both routinely acquired MRls and postmortem brain slices, thus improving the understanding of the pathological substrates and their progression.

Region-of-Interest Coding using Sub-Picture Slice Structure (내부 영상 슬라이스 구조를 이용한 관심 영역 부호화)

  • 김우식
    • Journal of Broadcast Engineering
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    • v.7 no.4
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    • pp.335-344
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    • 2002
  • A sub-picture slice structure is proposed which can perform the region-of-interest coding effectively, where the subjective quality can be improved by coding the region-of-interest in higher quality than the background region. In addition, the bit allocation mechanism is Proposed where the interval between quantization parameters of the foreground and background region is fixed. And the method to reduce the boundary effect between the foreground and background region is proposed. The foreground region is better protected to the network channel error than the background region. which results in the overall subjective quality improvement in the error prone environments.

CHEMICAL SHIFT IMAGING

  • Yi, Yun;Kim, Min-Gi
    • Proceedings of the KOSOMBE Conference
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    • v.1992 no.11
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    • pp.22-25
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    • 1992
  • Lipid component and water component image in living organism can be acquired due to its chemical shift difference. Various techniques for chemical shift imaging were used for acquiring separated image. It is necessary two imaging experiments to acquire two separated images wi th Dixon's method. This technique is less susceptible to local magnetic inhomogeneities and easily applied to multi-slice imaging. With CHESS and SECSI method, which based on chemical selectivity of R.F pusle, either water or lipid image can be acquired by one imaging experiment. However, those are more susceptible to local magnetic field inhomogeneities and difficult to apply to multi-slice imaging. The SECSI method showed best signal suppression ratio of fat and water, which is measure of separation of water and fat.

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Neuroprotective effects of vitamin C (비타민 C의 신경 보호 효과)

  • Sim, In-Seop;Lee, Kyeong-Hui;Kim, Eun-Jin;Cha, Myeong-Hun;Kim, Eun-Jeong;Kim, Ga-Min;Kim, Hyeong-A;Lee, Bae-Hwan
    • Proceedings of the Korean Society for Emotion and Sensibility Conference
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    • 2008.10a
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    • pp.147-150
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    • 2008
  • Vitamin C ascorbic acid (AA) and dehydroascorbic acid (DHA) as an antioxidant have been shown to have protective effects in experimental neurological disorder models such as stroke, ischemia, and epileptic seizures. The present study was conducted to examine the protective effect of AA and DHA on Kainic acid (KA) neurotoxicity using organotypic hippocampal slice cultures (OHSC). After 12h KA treatment, significant delayed neuronal death was detected in CA3 region, but not in CA1. Intermediate dose of AA and DHA pretreatment significantly prevented cell death and inhibit ROS level, mitochondrial dysfunction and capase-3 activation in CA3 region. In the case of low or high dose, however, AA or DHA pretreatment were not effective. These data suggest that both AA and DHA pretreatment have neuroprotective effects on KA-induced neuronal injury depending on the concentration, by means of inhibition of ROS generation, mitochondrial dysfunction, and caspase-dependent apoptotic pathway.

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Comparative study on alveolar bone height of pantomography and multi planar reformatted computed tomography (파노라마방사선사진과 다면상재구성 CT상의 치조골 높이 계측에 대한 비교 연구)

  • Ji Jung-Hyun;Lee Sang-Rae;Lee Byung-Do
    • Imaging Science in Dentistry
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    • v.34 no.3
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    • pp.159-164
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    • 2004
  • Purpose: To compare alveolar bony height of pantomograph with bony height of thin slice, multiplanar reformatted (MPR) Computed Tomograph. Materials and Methods : Panoramic radiograms of 12 young adult patients had been taken by one radologic technitian and the measurements were corrected by magnification ratio (1.20). The slice thickness of Multi-detector Computed Tomography (CT) was at least 1mm for the accuracy. The raw CT datas were imported into the V-works 4.0 (CyberMed Corp., Seoul, Korea) and transformed to MPR images. Pantomographic measurements of alveolar bone were compared to CT values by average mean bony height measurements for the accuracy. Inter-, and Intra-observer variability was evaluated. Results : There was no significant differences between height measurement of pantomography and that of CT (P>0.05). There were no significant differences in either inter-or intra-observer measurements (P>0.05). Conclusion : Pantomography showed relatively high accuracy and precision in measuring alveolar bony height.

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FRACTAL DIMENSIONS OF INTERSTELLAR MEDIUM: I. THE MOLECULAR CLOUDS IN THE ANTIGALACTIC CENTER

  • LEE YOUNGUNG
    • Journal of The Korean Astronomical Society
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    • v.37 no.4
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    • pp.137-141
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    • 2004
  • We have estimated the fractal dimension of the molecular clouds in the Antigalactic Center based on the $^{12}CO$ (J = 1- 0) and $^{13}CO$ (J = 1- 0) database obtained using the 14m telescope at Taeduk Radio Astronomy Observatory. Using a developed code within IRAF, we were able to identify slice-clouds, and determined the dispersions of two spatial coordinates as well as perimeters and areas. The fractal dimension of the target region was estimated to be D = 1.34 for low resolution $^{12}CO$ (J = 1 - 0) database, and D = 1.4 for higher resolution $^{12}CO$ (J = 1 - 0) and $^{13}CO$ (J = 1 - 0) database, where $P {\propto} A^{D/2}$. The sampling rate (spatial resolution) of observed data must be an important parameter when estimating fractal dimension. Our database with higher resolution of 1 arcminute, which is corresponding to 0.2 pc at a distance of 1.1 kpc, gives us the same estimate of fractal dimension to that of local dark clouds. Fractal dimension is apparently invariant when varying the threshold temperatures applied to cloud identification. According to the dispersion pattern of longitudes and latitudes of identified slice-clouds, there is no preference of elongation direction.

Effect of renal ischemia on amino acid transport in rabbit renal cortical slices (신장 허혈이 토끼 신피질 절편에서 아미노산 이동에 미치는 영향)

  • Nam, Yun-jeong;Kim, Joo-heon
    • Korean Journal of Veterinary Research
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    • v.37 no.1
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    • pp.111-117
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    • 1997
  • This study was carried out determine the effect of renal ischemia on amino acid transport in rabbit renal cortical slices. The animal models of renal ischemia induced experimentally by clamping the renal artery. These results were summarized as follows: 1. The uptake of amino acids lysine and ${\alpha}$-aminobutyrate(AIB), dicarboxylate succinate and organic anion PAH in cortical slices was normal or increased after 30 or 60 min of ischemia in vivo. 2. In a 30 min ischemic kidney, the slice uptake of amino acids was returned to the control level by 30 min of reflow. In a 60 or 90 min ischemic kidney, the lysine uptake was returned to the control level after of reflow, but the uptake of AIB and succinate was significantly reduced during reflow period of 30-120 min. 3. Oxygen consumption in cortical slices was increased after 30 min of ischemia but was not altered by 60 min of ischemia. This results indicat that transient ischemia caused increasing of amino acid uptake in renal cortical slices without metabolic disorder of renal proximal tubule.

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Investigation of Radial Distributions of Tangential Strains and of Moisture Contents within a Log Cross Section by Circumferential Slices

  • Choi, Jun-Ho;Lee, Nam-Ho
    • Journal of the Korean Wood Science and Technology
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    • v.36 no.2
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    • pp.20-28
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    • 2008
  • This study was carried out to provide the so-called circumferential slicing method for investigating radial distributions of the tangential strains and of moisture contents within the log cross section (LC) of Kalopanax pictus during indoor drying it. While the heartwood showed an almost uniform moisture content distribution in the range of about 50~55% in case of the green wood, it has gradually decreased toward the outer side, showing about 19% of moisture content difference from the innermost slice. Although the moisture gradient along the radial direction has gradually become gentle as drying progresses, the sapwood of the outer side represented the moisture contents below the fiber saturation point after 24 hours of drying while the heartwood in the inner part showed the moisture contents higher than the fiber saturation point. The pith side was laid under the tensile stress after 24 hours of drying, and then gradually decreasing toward the bark side, and showed the distribution being switched again to the tensile stress on the bark side. As the drying has progressed, this trend got more intensified, and finally showed the U-shaped distribution model after 48 hours of drying. The circumferential slice test is considered to be suitable in quantitatively determining the tangential strains and moisture content within a LC.

Design of RS Encoder/Decoder using Modified Euclid algorithm (수정된 유클리드 알고리즘을 이용한 RS부호화기/복호화기 설계)

  • Park Jong-Tae
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.8 no.7
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    • pp.1506-1511
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    • 2004
  • The error control of digital transmission system is a very important subject because of the noise effects, which is very sensitive to transmission performance of the digital communication system It employs a modified Euclid's algorithm to compute the error-location polynomial and error-magnitude polynomial of input data. The circuit size is reduced by selecting the Modified Euclid's Algorithm with one Euclid Cell of mutual operation. And the operation speed of Decoder is improved by using ROM and parallel structure. The proposed Encoder and Decoder are simulated with ModelSim and Active-HDL and synthesized with Synopsys. We can see that this chip is implemented on Xilinx Virtex2 XC2V3000. A share of slice is 28%. nut speed of this paper is 45Mhz.