• Archives of Pharmacal Research
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• v.28 no.9
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• pp.1079-1085
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• 2005

The purpose of this study was to investigate the safety of chitosan oligosaccharide and the effects of chitosan oligosaccharide on mercury induced genotoxicity in mice using the micronuclei and chromosome aberration. The micronuclei test was performed by microscopic examination $(\times1,000,\;stained\;using\;a\;May-Grunwald\;solution)$ after administering 0.01, 0.1, and $1\%(10\;mg/mL)$ chitosan oligosaccharide for 7, 60, and 180 days ad libitum in mice. Total micronuclei of 1,000 polychromatic erythrocytes were recorded for each group. There was no difference between the untreated and experimental groups. The intake periods and concentrations of chitosan oligosaccharide did not affect the occurrence of micronuclei in bone marrow cells (P>0.05). The chromosomal aberration test was performed by microscopic examination $({\times}1,000,\;stained\;using\;a\;4\%\;Giemsa\;solution)$ after administering the same concentration of chitosan oligosaccharide to mice, in $F_1,\;F_2,\;F_3$ generations and parents. The frequency of chromosomal aberrations was defined as [Ydr=(D+R)/total number of counted lymphocytes]. Similar to the micronuclei test, there was no difference between the untreated and treated groups. These results showed that the intake periods and concentrations of chitosan oligosaccharide did not affect chromosomal aberrations in bone marrow cells (P>0.05). To investigate the effect of chitosan oligosaccharide on mercury-induced chromosome aberration, mice in each condition were supplied with $^{203}HgCl_2$ and chitosan oligosaccharide ad libitum. Chitosan oligosaccharide significantly inhibited $^{203}HgCl_2-induced$ chromosome aberration in mice. Based on the results of this study, it may be concluded that the chitosan oligosaccharide is a nontoxic material that could be used as a suppressor of heavy metal-induced genotoxicity.

• Journal of the Korean Society of Clothing and Textiles
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• v.34 no.12
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• pp.2073-2084
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• 2010

This study provides references that can be applied to future suit design by analyzing the formative characteristics of modern men's and women's suits. Research on related literature and case studies were carried out simultaneously. A criterion for analyzing formative characteristics of suits was drawn up through an examination of past research. A total of 1,410 suit photographs that appeared in the U.S. edition of Vogue Magazine from 1985 to 2008 were analyzed in order to observe the formative characteristics of men's and women's suits. Research results showed that in the 1980s suits pursued a more comfortable and natural fit based on the original properties of simplicity, modernity, and practicality; in addition, women's suits had a tendency to use excessive shoulder pads due to the power-look influence. In the early 1990s exaggerated shoulders and boxy straight silhouettes were in fashion but towards the later years suit designs gradually started to fit the body and established a skinny versus slouch conflict. Women's suits gradually began to show more curvy body lines, and men's suits became more feminine on the surface in terms of color and material. In the 2000s suits have become more feminine and sensual than the 1990s, design focuses of both men's and women's suits moved to the waistline. Skinny and long styles became the ideal silhouette and differences between formative characteristics of the two genders decreased. Fashion elements of men's and women's suits are seen to have changed with a mutual intimate connection under the influence of a similar societal environment.

• Korean Journal of Food Science and Technology
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• v.49 no.3
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• pp.229-234
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• 2017

For elderly individuals with swallowing difficulties, texture-modified food containing thickeners is needed. The plant materials freeze-dried yam, lotus root, and artichoke were evaluated for their potential use as thickeners and compared to a commercial thickener (corresponding to 0.5, 1, or 2 bag viscosity, respectively). Yam powder showed a high peak viscosity, corresponding to that of rice starch. Although artichoke showed no pasting viscosity, it may be useful as a thickener when combined with xanthan gum. The certain amount of yam, lotus root, and artichoke powders added to commercial soup showed similar viscosities as the addition of 0.5 or 1 bag commercial thickener at $60^{\circ}C$. However, sufficient viscosity corresponding to that of 2 bags of commercial thickener was not achieved by using the plant material itself. Sensory tests by elderly subjects revealed that the soup with yam powder was preferred compared to soup made with other materials.

• Korean Journal of Ecology and Environment
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• v.41 no.3
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• pp.294-300
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• 2008

The stable isotopes ratios ($\delta^{13}C\;and\;\delta^{15}N$) of two coexisting species of zooplankton (Daphnia longispina and Acanthodiaptomus pacificus) and POM were determined in two alpine lakes in Japan. The difference of $\delta^{13}C$ between A. pacificus and D. longispina was 4.1$\pm$0.9‰ in Lake Shirakoma, which was larger than in Lake Panke. Whereas the difference of $\delta^{15}N$ between A. pacificus and D. longispina (2.6$\pm$0.8‰) was larger in Lake Panke than in Lake Shirakoma. $\delta^{13}C$ of POM (-26.6$\pm$1.2‰) in Lake Shirakoma was different from those of zooplankton; it was heavier than those of D. longispina and A. pacificus by 3.7$\pm$1.6‰ and 7.8$\pm$1.0‰, respectively. Whereas $\delta^{15}N$ of POM (2.0$\pm$0.8‰) was similar with those of both A. pacificus and D. longispina. This implies that the two lakes may have different trophic structure and food sources for zooplankton, and each species are grazing on selectively different components of POM. The temporal variation of $\delta^{13}C$ for each zooplankton species was associated with lipid contents of zooplankton in both lakes. The results showed that stable isotope composition of zooplankton can be an useful information for understanding energy pathways and trophic structures in lakes.

• Ecology and Resilient Infrastructure
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• v.5 no.3
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• pp.156-162
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• 2018

This research aimed at analyzing comparison results between in gravel and sand bed with respect to the detailed Acoustic Doppler Current Profiler (ADCP) measurement in a velocity, depth, and flow rate data based on Acoustic Doppler Velocimeter (ADV) measurement result. Conclusionally, similar results were shown for gravel and sand bed in velocity, depth and flow rate data using ADV and ADCP measurement. The results of the flow rate show a relative error mean of 3.5 - 4.8% in the gravel bed and 0.02 - 3.2% in the sand bed, which is better performance than the mean error of 5% suggested by United States Geological Survey (USGS). The results can be used as a basis data for the measurement of ADCP and potentially able to be utilized for the more detailed uncertainty analysis of ADCP flow rate measurement.

• Science of Emotion and Sensibility
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• v.6 no.3
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• pp.21-28
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• 2003

This study investigated the differences in processing type of working memory between experts and novices when they read music scores. Two experiments were conducted with the articulatory suppression condition. In Experiment 1, eight half notes were shown on the screen for a brief period of time, participants were then requested to write the notes on a music sheet. the stimuli were divided into two: melodious and unmelodious. In similar fashion, Experiment 2 consisted of four-chord sequences, which contained three notes each. The stimuli were also divided into two: harmonious and disharmonious. As an analysis of the results in Experiment 1 & 2, novices commonly showed better performances in the non-articulatory suppression condition than the articulatory suppression condition with both stimuli types. However, experts were relatively affected little by the articulatory suppression with harmonious stimuli. These findings support that while novices entirely depend on the articulatory loop, experts may encode the notes through the visuo-spatial sketchpad before they transfer the information to the phonological store when they are familiar with material.

• International Journal of Highway Engineering
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• v.3 no.4 s.10
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• pp.105-116
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• 2001

This study was performed to evaluate the characteristics of waste foundry sand (WFS) and the asphalt mixture made of a foundry waste sand. To estimate the applicability of WFS, chemical and physical properties were measured by XRF(X-ray fluorescent), and SEM(Scanning electronic microfilm). To improve the stripping resistance of WFS asphalt mixture, anti-stripping agents (a hydrated lime and a liquid anti-stripping agent) were used. To improve tensile properties and durability of WFS asphalt concrete mixture, LDPE(low-density polyethylene) was used as an asphalt modifier Marshall mix design, indirect tensile strength, tensile strength ratio(TSR) after freezing and thawing, moisture susceptibility and wheel tracking tests were carried out to evaluate performance of WFS asphalt concrete. Comparing with conventional asphalt concrete, WFS asphalt concretes showed similar or the better qualify in mechanical properties, and satisfied all specification limits. Therefore, it Is concluded that waste foundry sand can be recycled as an asphalt pavement material.

• International Journal of Highway Engineering
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• v.14 no.5
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• pp.31-45
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• 2012

PURPOSES: In Korea, rapid maintenance of distressed concrete pavement is required to prevent traffic jam of the highway. Asphalt concrete overlay has been used as a general maintenance method of construction for aged concrete pavement. AC overlay on existing concrete pavements experience various early distresses such as reflection crack, pothole and rutting, due to different physical characteristics between asphalt overlay and existing concrete pavement. Bonded concrete overlay(BCO) is a good alternative since it has advantages that can reduce various distresses during the service life since overlay material has similar properties with existing concrete pavements. Recently, BCO which uses the ultra rapid harding cement has been applied for maintenance of highway. BCO has advantage of structural performance since it does monolithic behave with existing pavement. Therefore, it is important to have a suitable bond strength criteria for securing performance of BCO. Bond strength criteria should be larger than normal tensile stress and horizontal shear stress occurred by traffic and environmental loading at bond interface. Normal tensile stress and horizontal shear stress need to estimated for the establishment of practical bond strength criteria. METHODS: This study aimed to estimate the bond stresses at the interface of BCO using the three dimensional finite element analysis. RESULTS: As a result of this study, major failure mode and maximum bond stress are evaluated through the analysis of normal tensile stress and horizontal shear stress for various traffic and environmental load conditions. CONCLUSIONS: It was known that normal tensile stresses are dominated by environmental loading, and, horizontal shear stresses are dominated by traffic loading. In addition, bond failure occurred by both of normal tensile stresses and horizontal shear stresses; however, normal tensile stresses are predominated over horizontal shear stresses.

• Toxicological Research
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• v.24 no.2
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• pp.151-159
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• 2008

Rhus verniciflua Stokes(RVS), one of traditional medicinal plants in Asia, was found to have pharmacological activities such as antioxidative and antiapoptotic effects, raising the possibility for the development of a novel class of anti-cancer drugs. Thus, potential genotoxic effects of RVS in three short-term mutagenicity assays were investigated, which included the Ames assay, in vitro Chromosomal aberration test, and the in vivo Micronucleus assay. In Ames test, the addition of RVS water extracts at doses from 313 up to 5000 mg/plate induced an increase more than 2-fold over vehicle control in the number of revertant colonies in TA98 and TA1537 strains for detecting the frame-shift mutagens. The similar increase in reversion frequency was observed after the addition of RVS ethanol extracts. To assess clastogenic effect, in vitro chromosomal aberration test and in vivo micronucleus assay were performed using Chinese hamster lung cells and male ICR mice, respectively. Both water and ethanol extracts from RVS induced significant increases in the number of metaphases with structural aberrations mostly at concentrations showing the cell survival less than 60% as assessed by in vitro CA test. Also, there was a weak but statistically significant increase in number of micronucleated polychromatic erythrocytes(MNPCEs) in mice treated with water extract at 2000 mg/kg while ethanol extracts of RVS at doses of up to 2000 mg/kg did not induce any statistically significant changes in the incidence of MNPCEs. Therefore, our results lead to conclusion that RVS acts as a genotoxic material based on the available in vitro and in vivo results.

• The Korean Journal of Food And Nutrition
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• v.10 no.2
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• pp.180-185
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• 1997

Sikye was produced from glutinous rice. The glutinous rice Sikhye was found to contain 7.3% of limit dextrin, 10.1% of maltose, 1.3% of maltotriose and 1.75% of rice residue. Limit dextrin in glutinous rice Sikhye was purified by ethanol fractionation followed by gel chromatography on Biogel P-2. The purified limit dextrin showed both signal of $\alpha$-1,4- and $\alpha$-1,6-glucosidic linkage with its estimation ratio of 5:1 by 1H-NMR analysis. Limit dextrin was digested with enzymes(30units/ml) of $\alpha$-amylase, $\alpha$-glucosidase and glucoamylase from Aspergillus awamori, sweet potato $\beta$-amylase and human salivary $\alpha$-amylase at 37$^{\circ}C$ for 1 hour, respectively. Hydrolysis rates of these amylases on it were similar that of rice Sikhye. $\alpha$-Glucosidase plus human salivary $\alpha$-amylase hydrolyzed it to 18%. The results suggest that glutinous rice is more effective to produce high level of branched maltooligosaccharide compared with rice as raw material for Sikye making.