• Journal of Electrochemical Science and Technology
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• 제1권2호
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• pp.121-126
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• 2010

An amperometric ascorbic acid selective sensor utilizing the transfer reaction of proton liberated from the dissociation of ascorbic acid in aqueous solution across an elliptic micro-hole water/organic gel interface is demonstrated. This redox inactive sensing platform offers an alternative way for the detection of ascorbic acid to avoid a fouling effect which is one of the major concerns in redox based sensing systems. The detection principle is simply measuring the current change with respect to the assisted transfer of protons by a proton selective ionophore (e.g., ETH 1778) across the micro-hole interface between the water and the polyvinylchloride-2-nitrophenyloctylether gel phase. The assisted transfer reaction of protons generated from ascorbic acid across the polarized micro-hole interface was first characterized using cyclic voltammetry. An improved sensitivity for the quantitative analysis of ascorbic acid was achieved using differential pulse stripping voltammetry with a linear response ranging from 1 to $100\;{\mu}M$ concentrations of ascorbic acid. As a demonstration, the developed sensor was applied for analyzing the content of vitamin-C in different types of commercial pharmaceutical tablets and syrups, and a satisfactory recovery from these samples were also obtained.

• Rapid Communication in Photoscience
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• 제4권4호
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• pp.88-90
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• 2015

The design and development of fluorescent chemosensors have recently been intensively explored for sensitive and specific detection of environmentally and biologically relevant metal ions in aqueous solution and living cells. Herein, we report the photophysical results of rhodamine B based fluorogenic and chromogenic receptor for selective copper detection in the complete organic or mixed aqueous-organic media at neutral pH under ambient condition. The ligand exhibited the remarkable increment in the fluorescence emission and UV-visible absorption signal intensities at 587 and 547 nm, respectively, on induction of copper ion while the ligand solution remain completely silent on addition of varieties of other metal ions.

• Bulletin of the Korean Chemical Society
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• 제23권3호
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• pp.481-487
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• 2002

A selective enzyme-linked immunosorbent assay (ELISA) for the insecticide chlorpyrifos was developed. Four haptens for chlorpyrifos were synthesized and two of them were used as immunogens after coupling to keyhole limpet hemocyanin by two differe nt approaches. Rabbits were immunized with either of them and the sera were screened against 4 haptens coupled to ovalbumin (OVA). Using the sera of highest specificity, an antigencoated ELISA was developed, which shows an I50 of 160 ppb with a detection limit of 10 ppb. An antibody-coated ELISA was also developed, which shows an $I_{50}$ of 20 ppb with a detection limit of 0.1 ppb. The antibodies showed negligible cross-reactivity with other organophosphorus pesticides except for insecticides chlorpyrifos-methyl and bromophos-ethyl, which makes these assays suitable for the selective detection of chlorpyrifos.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2012년도 제42회 동계 정기 학술대회 초록집
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• pp.540-540
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• 2012

Selective detection of single nucleotide polymorphism (SNP) of Cytochrome P450 2C19 (CYP2C19) was carried out by the PNA chips which were electrically-interfaced with interdigitated nanogap electrodes (INEs). The INEs whose average gap distance and effective gap length were about ~70 nm and ${\sim}140{\mu}m$, respectively, were prepared by the combination of the photo lithography and the surface-catalyzed chemical deposition, without using the e-beam lithography which is almost inevitable in the conventional lab-scale fabrication of the INEs. Four different types of target DNAs were successfully detected and discriminated by the INE-based PNA chips.

• Bulletin of the Korean Chemical Society
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• 제23권4호
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• pp.599-603
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• 2002

A selective enzyme-linked immunosorbent assay (ELISA) for the insecticide isofenphos was developed. Three different analogues (haptens) of isofenphos were synthesized and were coupled to carrier proteins through the pesticide thiophosphate group t o use as immunogens or coating antigens. Rabbits were immunized with one of the haptens coupled to BSA for production of polyclonal antibodies and the sera were screened against each of the other two haptens coupled to ovalbumin (OVA). Using the sera of highest specificity, an antigen-coated ELISA was developed, which showed an I50 of 96 ng/mL with the detection limit of 2 ng/mL. The antibodies showed negligible cross-reactivity with other organophosphorus pesticides and the phenol metabolite of isofenphos, which makes the developed assay suitable for the selective detection of isofenphos. An antibody-coated ELISA was also developed, which showed an I50 of 580 ng/mL with a detection limit of 70 ng/mL.

• 전자공학회논문지
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• 제53권6호
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• pp.15-20
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• 2016

OFDM 시스템을 위한 PAPR (peak-to-average power ratio) 저감 기법 중 하나인 SLM (selective mapping) 방식은 구현이 간단하고 전송 신호에 왜곡이 생기지 않는 매우 유용한 PAPR 저감 기법이다. 본 논문에서는 위상 신호에 대한 부가 정보(side information)를 전송하지 않는 SLM 기반 OFDM 시스템에 적용 가능한 동기식 위상 신호 검출 방식을 제시하고자 한다. 우선 동기식 합(coherent summation)에 기반하여 위상 신호를 검출할 수 있도록 하기 위해, 위상 신호의 일부를 직교 부호로 대치시키는 새로운 위상 신호 설계 방법을 제안한다. 또한 새로이 제안된 위상 신호에 기초하여 부가 정보가 필요 없는 동기식 위상 신호 검출 기준(detection criterion)을 제안한다. 컴퓨터 모의실험을 통해, 제안된 방식이 SLM 기반 OFDM 시스템에서 정상적으로 동작함을 보이고, 위상 신호 검출에 사용되는 부반송파 간 채널의 변화가 적은 환경에서 기존 방식보다 위상 신호 검출 성능이 우수함을 보이고자 한다.

• 한국통신학회논문지
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• 제31권12A호
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• pp.1198-1204
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• 2006

본 논문에서는 MIMO 시스템에서 제안된 SVR-MMSE 검출기법을 MIMO-OFDM 시스템으로 확장, 적용하고 주파수 선택적인 채널에서 성능을 분석한다. 우선 전형적인 MIMO-OFDM 시스템에 대해서 설명하고 이 시스템에서 constant modulus 신호의 검출기법에 대하여 설명을 한다. 기존의 검출 기법인 Zero Forcing, Minimum Mean Square Error 기법과 제안된 SVR-MMSE 검출의 성능을 비교해 보고, Jakes 채널 모델을 사용하여 지연확산을 가지는 다중 경로 페이딩 채널에서 도플러 주파수가 변화함에 따라 검출 기법의 성능을 알아본다. 본 논문에서 제안된 SVR-MMSE를 이용한 MIMO-OFDM 시스템에서의 검출 성능 모의실험 결과, 제안된 알고리즘이 이 시스템에서 우수한 성능을 지니고 있음을 보여주고 있다.

• Journal of Communications and Networks
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• 제14권5호
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• pp.501-509
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• 2012

This paper proposes a joint timing synchronization, channel estimation, and data detection for the impulse radio ultra-wideband systems. The proposed timing synchronizer consists of coarse and fine timing estimation. The synchronizer discovers synchronization points in two stages and performs adaptive threshold based on the maximum pulse averaging and maximum (MAX-PA) method for more precise synchronization. Then, iterative channel estimation is performed based on the discovered synchronization points, and data are detected using the selective rake (S-RAKE) detector employing maximal ratio combining. The proposed synchronizer produces two signals-the start signal for channel estimation and the start signal for start frame delimiter (SFD) detection that detects the packet synchronization signal. With the proposed synchronization, channel estimation, and SFD detection, an S-RAKE receiver with binary pulse position modulation binary phase-shift keying modulation was constructed. In addition, an IEEE 802.15.4a channel model was used for performance comparison. The comparison results show that the constructed receiver yields high performance close to perfect synchronization.

• 한국통신학회논문지
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• 제30권7A호
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• pp.628-638
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• 2005

The analysis of maximum diversity order and coding gain for multiple-input multiple-output orthogonal frequency division multiplexing (MIMO-OFDM) systems over time-and frequency-selective (or doubly-selective) channels is addressed in this paper. A novel channel time-space correlation function is developed given the spatially correlated doubly-selective Rayleigh fading channel model. Based on this channel-model assumption, the upper-bound of pairwise error probability (PEP) for MIMO-OFDM systems is derived under the maximum likelihood (ML) detection. For a certain space-frequency code, we quantify the maximum diversity order and deduce the expression of coding gain. In this wort the impact of channel time selectivity is especially studied and a new definition of time diversity is illustrated correspondingly

• Bulletin of the Korean Chemical Society
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• 제29권3호
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• pp.571-574
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• 2008

The well-known Cu2+-selective chemodosimetric behavior of rhodamine B hydrazide was successfully switched to selectivity for Hg2+. The fluorescence signaling is remarkably selective toward Hg2+ ions compared to other common biologically and environmentally important metal ions, including Cu2+ ions. The detection limit was 0.2 mM in an acetate-buffered aqueous 10% methanol solution at pH 5. The OFF-ON type of signaling is due to the selective Hg2+-induced hydrolysis of the lactam ring of the hydrazide as has been reported for the standard Cu2+-signaling process of the same compound. A simple change in medium resulted in clear switching of selective signaling from Cu2+ to Hg2+, which extends the applicability of the easily accessible hydrazide derivative.