Proceedings of the Korean Vacuum Society Conference (한국진공학회:학술대회논문집)
- 2012.02a
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- Pages.540-540
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- 2012
Fabrication of Nanogap-Based PNA Chips for the Electrical Detection of Single Nucleotide Polymorphism
- Park, Dae-Keun ;
- Park, Hyung-Ju ;
- Lee, Cho-Yeon ;
- Hong, Dae-Wha ;
- Lee, Young ;
- Choi, In-Sung S. ;
- Yun, Wan-Soo
- Published : 2012.02.08
Abstract
Selective detection of single nucleotide polymorphism (SNP) of Cytochrome P450 2C19 (CYP2C19) was carried out by the PNA chips which were electrically-interfaced with interdigitated nanogap electrodes (INEs). The INEs whose average gap distance and effective gap length were about ~70 nm and
Keywords
- Interdigitated nanogap electrodes (INEs);
- Cytochrome P450 2C19 (CYP2C19);
- PNA chip;
- Selective detection;
- Functionalized au nanoparticle