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신증후군 환아에서 발생한 광범위한 뇌정맥 혈전증 1례 (A Case of Extensive Cerebral Venous Thrombosis in Childhood Nephrotic Syndrome)

  • 손창희;이은혜;이주훈;박영서
    • Childhood Kidney Diseases
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    • 제10권2호
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    • pp.238-243
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    • 2006
  • Nephrotic syndrome in childhood is known to be associated with a hypercoagulable state and thromboembolic complications, among which cerebral venous thrombosis is a very rare and serious one, with only a few isolated reports in the literature. A 9-year-old boy with known nephrotic syndrome was admitted due to a relapse with massive proteinuria and generalized edema. He complained of a prolonged frontal headache. The enhanced brain magnetic resonance imaging(MRI) showed a high signal in the region of the superior sagittal sinus and right transverse sinus consistent with a thrombus. He was managed with steroids, cyclosporine and warfarin. His headache subsided 2 weeks later and proteinuria resolved 1 month later. An MRI 2 months later was normal. We describe this case and review the literature to emphasize the importance of recognizing this potentially life threatening complication and initiating anticoagulation therapy.

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Glandular papilloma of the lung with malignant transformation

  • Sung, Woo Jung
    • Journal of Yeungnam Medical Science
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    • 제34권2호
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    • pp.298-302
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    • 2017
  • Glandular papilloma of the lung is one of three histologic types of solitary endobronchial papillomas. It is known as an uncommon benign neoplasm. No malignant glandular papillomas have been reported. Herein, the first case of granular papilloma with malignant transformation is reported. A 74-year-old man with huge right lung mass extended upper and lower lobe was admitted to the hospital complaining of progressive cough and dyspnea. An open lung biopsy was performed. Microscopically, the tumor showed papillary growth pattern with thick fibrovascular cores. The stroma of the fibrovascular cores shown the infiltration of lymphoplasmacytic cells and proliferation of capillaries. The epithelial cells surrounding the papillary fronds were cilliated columnar cells with focal cellar atypia, and frequent mitoses. Suspicious pleural invasion foci were identified. The Ki-67 labeling index was about 24.3% and p53 labeling index was about 31.7%. Glandular papilloma is known as a benign neoplasm, which is lack of atypia and mitosis. In present case, there were several indications of malignant transformation, such as cellular atypia, frequent mitosis, architectural distortion, and pleural invasion. Pathologists must be aware that glandular papilloma can have a changes of malignant transformation. Further studies about disease behavior and molecular characteristics are needed.

A PRECONDITIONER FOR THE LSQR ALGORITHM

  • Karimi, Saeed;Salkuyeh, Davod Khojasteh;Toutounian, Faezeh
    • Journal of applied mathematics & informatics
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    • 제26권1_2호
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    • pp.213-222
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    • 2008
  • Iterative methods are often suitable for solving least squares problems min$||Ax-b||_2$, where A $\epsilon\;\mathbb{R}^{m{\times}n}$ is large and sparse. The well known LSQR algorithm is among the iterative methods for solving these problems. A good preconditioner is often needed to speedup the LSQR convergence. In this paper we present the numerical experiments of applying a well known preconditioner for the LSQR algorithm. The preconditioner is based on the $A^T$ A-orthogonalization process which furnishes an incomplete upper-lower factorization of the inverse of the normal matrix $A^T$ A. The main advantage of this preconditioner is that we apply only one of the factors as a right preconditioner for the LSQR algorithm applied to the least squares problem min$||Ax-b||_2$. The preconditioner needs only the sparse matrix-vector product operations and significantly reduces the solution time compared to the unpreconditioned iteration. Finally, some numerical experiments on test matrices from Harwell-Boeing collection are presented to show the robustness and efficiency of this preconditioner.

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한국 연안의 요각류 중 Acartia clausi로 분류되어지고 있는 종에 대한 재검정 및 분포에 대한 연구 (Taxonomic Re-examination and Distribution of Copepods known as Acartia clausi in the coastal waters of Korea)

  • 강영실;이삼석
    • 한국수산과학회지
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    • 제23권5호
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    • pp.378-384
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    • 1990
  • 한국 연안에서 보고되고 있는 Acartia clausi를 부산 연안역에서 채집된 종으로써 재검정하였다. 그 결과 지금까지 A. clausi로 분류되어졌던 종이 Acartia omorii이거나 A. hudsonica임이 밝혀졌다. 수컷의 경우, 제5각 오른쪽 세번째 마디절 내측에 있는 융기부의 형태에서 두종간의 뚜렷한 차이를 찾을 수 있다 A. omorii는 융기부의 아랫부분이 만곡되어 있으며, A. hudsonica는 원형으로 돌출되어 있다. 암컷의 경우, 생식절의 폭에 대한 길이의 비가 두 종간 중요한 분류 형질이 된다. 또한, A. omorii와 경우, 후제부의 두번째 마디절 등쪽 끝에 $1\~3$개의 소극을 가진 것이 특징이다. 한국 연안 8개의 지점에서 분포를 파악해 본 결과 A. omorii는 모든 조사지점에서 출현하였고, A. hudsenica는 부산 연안역에서만 출현하였다.

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지실(枳實)의 항알러지 작용에 대한 연구 (The Study on the Antiallergic Action of Poncirus trifoliata)

  • 김형균;이언정;권용택;황광호;주홍현;송봉근
    • 대한한방내과학회지
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    • 제21권1호
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    • pp.156-161
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    • 2000
  • The unripe fruit of Poncirus trifoliata Raf has been used for the treatment of allergic disease. Recently it was reported that the fruit inhibits passive cutaneous anaphylaxis and histamine release at mast cell. Type I immediate hypersensitivity of anaphylactic type is caused by released mediate chemical at mast cell. Histamine is also known as one of potent mediate chemical. Also release of mediate chemical is affected by specific stimulation of IgE combined with mast cell. Activation of mast cell is known to be stimulated by compound 48/80 and inhibited by increase of cAMP. In this experiment, the effect of water extract of Poncirus trifoliata Raf fruit (PT) on a histamine release, cAMP concentration and IgE production was measured. Compound 48/80 was administrated to the mouse peritoneal cell which was pretreated with PT. PT dosedependently inhibited histamine release at peritoneal mast cell and the serum level of histamine induced by compound 48/80. PT also instantly increased cAMP level of peritoneal mast cell right after it was added and the level gradually decreased. Production of IgE induced by antigens at mouse peritoneal cell was inhibited by PT. The IgE synthesis is induced by IL-4 and it is known that lipopolysaccharide(LPS) plus IL-4 cause an increase in IgE secretion by murine B cells. The effects of PT inhibited the production of IgE activated by LPS plus IL-4 at human U266B1 cells. These results indicate that PT has antiallergic activity by Inhibition of IgE production from B cells and histamine release by increase of cAMP.

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The Effects of Radiofrequency Catheter Ablation for Atrial Fibrillation on Right Ventricular Function

  • Minkwan Kim;Jae-Sun Uhm;Je-Wook Park;SungA Bae;In Hyun Jung;Seok-Jae Heo;Daehoon Kim;Hee Tae Yu;Tae-Hoon Kim;Boyoung Joung;Moon-Hyoung Lee
    • Korean Circulation Journal
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    • 제54권4호
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    • pp.203-217
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    • 2024
  • Background and Objective: The effects of radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) on right ventricular (RV) function are not well known. Methods: Patients who underwent RFCA for AF and underwent pre- and post-procedural echocardiography were enrolled consecutively. Fractional area change (FAC), RV free-wall longitudinal strain (RVFWSL), and RV 4-chamber strain including the ventricular septum (RV4CSL) were measured. Changes in FAC, RVFWSL, and RV4CSL before and after RFCA were compared among paroxysmal AF (PAF), persistent AF (PeAF), and long-standing persistent AF (LSPeAF) groups. Results: A total of 164 participants (74 PAF, 47 PeAF, and 43 LSPeAF; age, 60.8 ± 9.8 years; men, 74.4%) was enrolled. The patients with PeAF and LSPeAF had worse RV4CSL (p<0.001) and RVFWSL (p<0.001) than those with PAF and reference values. Improvements in RVFWSL and RV4CSL after RFCA were significant in the PeAF group compared with the PAF and LSPeAF groups (ΔRV4CSL, 8.4% [5.1, 11.6] in PeAF vs. 1.0% [-1.0, 4.1] in PAF, 1.9% [-0.2, 4.4] in LSPeAF, p<0.001; ΔRVFWSL, 9.0% [6.9, 11.5] in PeAF vs. 0.9% [-1.4, 4.9] in PAF, 1.0% [-1.0, 3.6] in LSPeAF, p<0.001). In patients without recurrence, improvements in RVFWSL and RV4CSL after RFCA were significant in the PeAF group compared to the LSPeAF group. Conclusions: RV systolic function is more impaired in patients with PeAF and LSPeAF than in those with PAF. RV systolic function is more improved after RFCA in patients with PeAF than in those with PAF or LSPeAF.

최소비용문제의 퇴화 정점 최적해에 대한 감도분석 (Sensitivity Analysis on the Degenerate Tree Solution of the Minimum Cost Flow Problem)

  • 정호연;박순달
    • 산업공학
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    • 제7권3호
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    • pp.193-199
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    • 1994
  • The purpose of this paper is to develop a method of the sensitivity analysis that can be applicable to a degenerate tree solution of the minimum cost flow problem. First, we introduce two types of sensitivity analysis. A sensitivity analysis of Type 1 is the well known method applicable to a spanning tree solution. However, this method have some difficulties in case of being applied to a degenerate tree solution. So we propose a sensitivity analysis of Type 2 that keeps solutions of upper bounds remaining at upper bounds, those of lower bounds at lower bounds, and those of intermediate values at intermediate values. For the cost coefficient, we present a method that the sensitivity analysis of Type 2 is solved by using the method of a sensitivity analysis of Type 1. Besides we also show that the results of sensitivity analysis of Type 2 are union set of those of Type 1 sensitivity analysis. For the right-hand side constant or the capacity, we present a simple method for the sensitivity analysis of Type 2 which uses arcs with intermediate values.

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A Surgical Case of Lymphocytic Hypophysitis with Progressive Visual Worsening

  • Shin, Hee-Sup;Park, Bong-Jin;Lim, Young-Jin
    • Journal of Korean Neurosurgical Society
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    • 제42권3호
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    • pp.216-219
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    • 2007
  • Lymphocytic hypophysitis is a clinically rare disease, and it has been known to be an autoimmune disease which mainly affects pregnant women at the end of gestation or right after delivery. The authors experienced a case of lymphocytic hypophysitis in a 29-year-old pregnant woman with rapid progressing visual disturbance. Sella MRI showed a mass-like lesion of hypophysis and hypertrophy of pituitary stalk with evidences of hypopituitarism. Cesarean section was done and then TSA was performed. The pathologic diagnosis was lymphocytic hypophysitis. After TSA, visual acuity was improved and visual field defect was recovered. She was given thyroid hormone replacement therapy because of transient partial hypopituitarism for 6 months after surgery. One must consider the probability of lymphocytic hypophysitis, if there are alteration of visual acuity and visual field defect which aggravate rapidly during pregnancy due to mass effect, decreased serum hormonal levels shown in hypopituitarism and sella MRI findings of hypertrophy of pituitary stalk and enlargement of pituitary gland.

First report of Pagurus erythrogrammus (Crustacea: Decapoda: Anomura) from Korea

  • Lee, Seok Hyun;Ko, Hyun Sook
    • Journal of Species Research
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    • 제6권spc호
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    • pp.54-57
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    • 2017
  • A pagurid crab, Pagurus erythrogrammus is described and illustrated for the first time from Korean waters. It was collected by SCUBA diving in Seogwipo (Jejudo Island) on 30 May 2013. Its morphology is similar to those of known Korean species of the family Paguridae: Boninpagurus pilosipes, Pagurus nigrivittatus, and Pagurus quinquelineatus. This species, however, it is distinguished by having a developed rostrum, seven rows of spines on dorsal surface of the right palm in male, a row of spines on the medial surface of the dactylus of the third pereopod, 12 long ventral spines of dactylus of the third pereopod, six small spines on the concaved distal margin of telson, and three reddish brown lines on lateral surfaces of propodi of the second and third pereopods.

Tetralogy of Fallot with Subarterial Ventricular Septal Defect

  • Kim, Sam-Hyun;Seo, Dong-Man;Park, Pyo-Won;Song, Meong-Gun;Park, Young-Kwan;Lee, Young-Kyoon
    • Journal of Chest Surgery
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    • 제21권1호
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    • pp.82-86
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    • 1988
  • Tetralogy of Fallot with subarterial ventricular septal defect is known to be relatively common in the Far East. Among the 140 consecutive patients who underwent repair for tetralogy, 15 [10,7@] had this variant form of tetralogy. Though the degree of pulmonic stenosis seems only mild or moderately severe because of the absence of infundibular septum and relatively large size of pulmonary arteries in this type of tetralogy, it has a special surgical implication that a patch widening of the right ventriculotomy is necessary in every case to avoid the postoperative subpulmonic stenosis. A morphological and surgical features of tetralogy with subarterial VSD are presented.

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