• Proceedings of the Korean Society for Bioinformatics Conference
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• 2001.10a
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• pp.29-44
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• 2001

DNA damage by physical insult including UV and g-radiation might provoke genetic alterations in cells, which is followed by either acute cell death or tumorigenesis. The responsiveness to g-radiation depends on cellular context of target cells. To understand the mechanisms of checkpoint control, repair and cell death following genotoxic stimu]i, cDNA microarray can provide the gene expression profile. To make a profile of gene expression in irradiated Jurkat T cells, we hybridized the cDNA microarray using cDNA from g-irradiated Jurkat T cells. Jurkat T cells were exposed to 4Gy to 16Gy, and total RNA were extracted at 4 to 24 hrs after irradiation. The hybridization of the microarray to fluorescence-labeled cDNA from treated and untreated cells was analyzed by bioinformatic analysis to address relative changes in expression levels of the genes present in the array. Responses varied widely in different time points, suggesting acute stress response and chronic restoration or cell death. From these results we could select 384 genes related to radiation response in Tcells, and radiation response might be different in various types of cells. Using Radchip, we could separate "the exposed" from control PBMCs. We propose that Radchip might be useful to check the radiation research as well as radiation carcinogenesis.

• Bulletin of the Korean Space Science Society
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• 2010.04a
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• pp.39.3-39.3
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• 2010

Solar-terrestrial links in short-time scales(daily ~monthly) are extensively explored in recent years: such as a response of low cloud amounts to the Forbush decrease, a response of Northern Atlantic oscillation index to sudden increase in electric field intensity of solar wind and so on (e.g., Svensmark et al., 2009; Boberg & Lundstedt, 2002). In this study, we perform the superposed epoch analysis to see any possible response of the sea-level pressure over Korean peninsula to the fast solar wind stream. Data sets are daily values, and zero days are determined to be days when the solar wind velocity exceeds 800km/s. Average profile of superposed sea-level pressure shows a gradual increase during the first 2 days and a decrease afterward below the normal level with a low pressure condition maintained for a few days. This result indicates that the sea-level pressure may respond to the fast solar wind stream. In other words, the average profile of sea-level pressure mimics the average velocity profiles. The correlation coefficient between two average profiles is 0.80, with 2 day lag.

• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2003.03a
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• pp.129-139
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• 2003

The response displacement method is the most frequently used method for seismic design of buried structures. This method is pseudo-static method, and the evaluations of velocity response spectrum of seismic base and response displacement of surrounding soil are the most important steps. In this study, the evaluation of velocity response spectrum of seismic base according to the Korean seismic design guide and the simple method of calculating the response displacement were studied. It was found that velocity response spectrum of seismic base can be estimated by direct integrating the ground-surface acceleration response spectrum of soil type $S_{A}$, and the evaluation of the response displacement using double cosine method assuming two layers of soil profile shows the advantages in the seismic design.n.

• Communications for Statistical Applications and Methods
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• v.27 no.1
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• pp.15-35
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• 2020

In research on behavioral studies, significant attention has been paid to the stage-sequential process for multiple latent class variables. We now explore the stage-sequential process of multiple latent class variables using the multivariate latent class profile analysis (MLCPA). A latent profile variable, representing the stage-sequential process in MLCPA, is formed by a set of repeatedly measured categorical response variables. This paper proposes the extended MLCPA in order to explain an association between the latent profile variable and the latent group variable as a form of a two-dimensional contingency table. We applied the extended MLCPA to the National Longitudinal Survey on Youth 1997 (NLSY97) data to investigate the association between of developmental progression of depression and substance use behaviors among adolescents who experienced Authoritarian parental styles in their youth.

• 제어로봇시스템학회:학술대회논문집
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• 2002.10a
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• pp.46.5-46
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• 2002

As device dimension shrinks down to sub 100nm, it is increasingly important to monitor plasma states. Plasma etching is a key means to fine patterning of thin films. Many parameters are involved in etching and each parameter has different impact on process performances, including etch rate and profile. The uniformity of etch responses should be maintained high to improve device yield and throughput. The uniformity can be measured on any etch response. The most difficulty arises when attempting to characterize etched profile. Conventionally, the profile has been estimated by measuring the slope or angle of etched pattern. One critical drawback in this measurement is that this is unable to cap...

• Journal of Biomedical Engineering Research
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• v.25 no.5
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• pp.329-334
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• 2004

The electronic nose (E-nose) recently finds its applications in medical diagnosis, specifically on detection of diabetes, pulmonary or gastrointestinal problem, or infections by examining odors in the breath or tissues with its odor characterizing ability. The odor recognition performance of E-nose can be improved by manipulating the sensor array responses of vapors in time-profile forms. The different chemical interactions between the sensor materials and the volatile organic compounds (VOC's) leave unique marks in the signal profiles giving more information than collection of the conventional piecemal features, i.e., maximum sensitivity, signal slopes, rising time. In this study, to use them in vapor recognition task conveniently, a novel time-profile method was proposed, which is adopted from digital image pattern matching. The degrees of matching between 8 different vapors were evaluated by using the proposed method. The test vapors are measured by the silicon-based gas sensor array with 16 CB-polymer composites installed in membrane structure. The results by the proposed method showed clear discrimination of vapor species than by the conventional method.

• Journal of the Korea Society of Computer and Information
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• v.21 no.12
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• pp.115-124
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• 2016

In this paper, a method to generate the extended model automatically on the critical elements in enterprise system based real time distributed architecture as well as the platform specific model(PSM) for Microsoft(MS) .NET platform is proposed. The key ideas of this method are real time distributed architecture should performed with satisfying strict constraints on life cycle of object and response time such as synchronization, transaction and so on, and .NET platform is able to implement functionalities including before mentioned by only specifying Attribute Code and maximizing advantages of MDA. In order to realize the ideas, functionalities which should be considered enterprise system development are specified and these are to be defined in Meta Model and extended UML profile. In addition, after definition of UML profile for .NET specification, by developing and applying these into plug-in of open source MDA tool, and extended models are generated automatically through this tool. Accordingly, by using proposed specification technology, the profile and tools easily and quickly reusable extended model can be generated even though low level of detailed information for functionalities which is considered in .NET platform and real time distributed architecture. In addition, because proposed profile is MOF which is basis of standard extended and applied, UML and MDA tools which observed MOF is reusable.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.8 no.3
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• pp.9-14
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• 2008

In this paper, we propose the channel sounding scheme which is made for ideal communication between some application as well as the short distance of high speed data transmission in MIMO-OFDM system for Wireless PAN. This method is able to perceive the duration of the impulse response through the delaying of power delay profile, modeled a power delay profile which has an attenuate characteristic, and obtained the coefficient of channel response by ML (maximum likelihood). Through the amplitudes, phases and delays associated with each multipath component which were acquired from this channel sounding scheme, we can describe the wave propagation characteristics of channels between the transmitter and receiver so that the receiver could enhance not only the reliability but also the ability of communication link.

• The korean journal of orthodontics
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• v.14 no.1
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• pp.161-172
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• 1984

This study was undertaken to evaluate the cephalometric changes of the soft tissue and skeletal profile subsequent 10 the rapid palatal expansion in 25 Angle's Class III cases, ranging in age from six to fifteen years, with cross-bite of the anterior teeth, underdevelopment of maxilla and facial disharmony Following results were obtained: 1. ANS moved downward, Point A presented forward & downward movement increasing SNA and Point B presented backward & downward movement decreasing SNB. 2. Mandible was rotated to backward & forward and maxilla moved forward & downward with the bite opening and improvement of anterior teeth cross-bite. 3. Soft tissue on mandible was rotated to backward & forward following hard tissue changes causing the decrease of facial convexity angle and backward & downward rotation of Point B', Pog'. 4. Response of the upper lip was more significant in downward than forward direction, and correlated with the upper central incisor and mandible rotation. 5. Response of the lower lip was more significant in downward than backward direction, and correlated with the mandible rotation. 6. There was a rather high degree of correlation between skeletal profile and soft-tissue profile, 1 : LS, $\bar{1}$:Pog', Pog:LS, Pog:LI, Pog:Pog' in horizontal measurements and $\bar{1}$:Pog', Pog:LI, Pog:Pog' in vertical measurements.

• Journal of the Earthquake Engineering Society of Korea
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• v.9 no.6 s.46
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• pp.67-73
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• 2005

Precise analysis of soil-structure interaction requires a proper description of soil profile. However, such approach becomes generally nearly unpractical for soil exhibiting material discontinuity and complex geometry since meshes should match that material discontinuity line. To overcome these difficulties, a different numerical integration method is adopted in this paper, which enables to integrate easily over an element with material discontinuity without regenerating mesh fellowing the discontinuity line. As a result the mesh is highly structured, loading to very regular silliness matrix. The influence of the shape of soil profile on the response is examined and it is seen that the proposed soil-structure analysis method can be easily used on soil-structure interaction problems with complicated soil profile and produce reliable results regardless of material discontinuities.