Background: A relation between abdominal obesity and colorectal tumor development has been reported repeatedly, and is believed to be more remarkable in man than in women. However, the details vary depending on scientific reports. This may be due at least partly to the selected surface anthropometric index in addition to the influence of gender and ethnic groups. To cope with this, we considered a new index of abdominal obesity and evaluated its risk prediction potential. Materials and Methods: Six hundred ninety five Japanese (262 women and 433 men) who had a colonoscopy were studied. The new index was named as waist circumference to height index (WHI) and was calculated by the formula of waist circumference (cm)/height (m)/height (m). Biochemical and lifestyle factors were investigated preceding the colonoscopy. Statistical analysis was performed using SPSS for Windows. Results: Increase of WHI was associated with altered metabolism of carbohydrate and lipid in both women and men. WHI was positively related with the development of colon tumor of women, while not with that of men. Logistic regression analysis performed for stratified age groups (45-54, 55-64 and 65-74 years) showed that WHI significantly increased odds ratio to 1.31 (CI 1.05-1.64 p=0.01) in women of 55-65 years. In contrast, in men this index WHI reduced the odds ratio insignificantly, while low density lipoprotein and triglyceride significantly increased the odds ratio to 1.01 (CI 1.00-1.03 p=0.02) in the 55-65 year group and to 1.02 (CI 1.00-1.03 p=0.02) in the 45-55 year group. Conclusions: In Japanese the risk factors for colon tumor development are different between women and men. WHI is a simple and efficient predictor of colon tumor risk in Japanese women and may be used to select those who should have colonoscopy.
Background: Lymphangiogenesis, assessed as lymphovascular density (LVD), is the initial step of generalized tumor lymphovascular invasion (LVI). It also involves VEGF-C as the most important protein family. Lymphangiogenesis among breast cancer cases correlations with several clinicopathological factors are important to determine prognosis and treatment strategies, but results have been controversial and require clarification. Aim: To define correlations between VEGF-C expression, LVD and LVI with several clinicopathological parameters from Indonesian breast cancer patients. Materials and Methods: Using a cross-sectional study, a total of 48 paraffin-embedded tissues of breast cancer from Dr. Sardjito General Hospital Indonesia were assessed for VEGF-C expression, LVD and LVI by immunohistochemistry. Correlations of these markers with clinicopathological parameters like patient age, tumor size, lymph node status, grade, ER/PR and Her-2 status, cell proliferation and p-53 expression were investigated by linear analysis. Correlations of VEGF-C expression and LVI with several clinicopathological parameters were analyzed with Coefficient Contingency Chi-Square test. Results: The mean of patients age was 53.0 year, pre and post-menopausal patients accounting for 56.3% and 43.8%, respectively. Some 10.4% were well, 41.7% moderate and 47.9% poorly differentiated. ER positivity was evident in 50% while PR and Her-2 positivity was found in 31.3% and 33.3%, respectively. Breast cancer cells with over-expression of p-53 was 64.6% and with high cell proliferation was 56.3%. Lymph node metastasis was noted in 63.5%, and LVI in 72.9%. Significant correlations were found between LVD and tumor size (p:0.037), grade (p:0.000), lymphnode status (p:0.036), LVI (p:0.003), as well as with p-53 and cell proliferation. There were also significant correlation of VEGF-C (p:0.011) and LVI (p:0.001) with tumor grade. Only ER status was found to have a correlation with tumor size (p:0.027). Conclusions: This study suggested that in Indonesian breast cancer patients, lymphangiogenesis is correlated with tumor size, grade, lymph node status and tumor lymphovascular invasion, the latter also being related with p-53 over expression and high cell proliferation.
Journal of the Korean Institute of Landscape Architecture
/
v.41
no.6
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pp.199-208
/
2013
The purpose of this study is to compare the vegetation structure in complementary forests of villages between Korea and China. For this study, Jinan in Korea and Qingzhou in China were selected through a pre-survey about the representative regions of both countries. The main research method used was field study. A comparative analysis between the two regions was performed by a frequency analysis of the surveyed data. The data obtained in the study shows the vegetation structure in complementary forests of villages in the two regions have many differences which are related to the local culture. As a result, it was identified that the average number of species was the same at 2.9 and the average number of trees, total number of trees, and tree density in Qingzhou were considerably greater than those in Jinan. Also, it was identified that tree height, average breadth height diameter and crown width in Jinan were considerably greater than those in Qingzhou. Furthermore, it was identified that both the forest state and the principal species of tree are both very different according to the different cultures. Through this identification, it is considered that this study will be helpful in establishing policy direction in both countries about the restoration and management of complementary forests.
Journal of the Korean Institute of Electrical and Electronic Material Engineers
/
v.18
no.1
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pp.38-42
/
2005
B$_2$O$_3$ added Ba(Mg$_{1}$3/Nb$_{2}$3/)O$_3$ (BBMN) ceramics were not sintered below 900 $^{\circ}C$. However, when CuO was added to the BBMN ceramic, it was sintered even at 850 $^{\circ}C$. The amount of the $Ba_2$B$_2$O$_{5}$ second phase decreased with the addition of CuO. Therefore, the CuO additive is considered to react with the B$_2$O$_3$ inhibiting the reaction between B$_2$O$_3$ and BaO. Moreover, it is suggested that the solid solution of CuO and B$_2$O$_3$ might be responsible for the decrease of the sintering temperature of the specimens. A dense microstructure without pores was developed with the addition of a small amount of CuO. However, a porous microstructure with large pores was formed when a large amount of CuO was added. The bulk density, the dielectric constant ($\varepsilon$$_{r}$) and the Q-value increased with the addition of CuO but they decreased when a large amount of CuO was added. The variations of those properties are closely related to the variation of the microstructure. The excellent microwave dielectric properties of Qxf = 21500 GHz, $\varepsilon$$_{r}$ = 31 and temperature coefficient of resonance frequency($\tau$$_{f}$) = 21.3 ppm/$^{\circ}C$ were obtained for the Ba(Mg$_{1}$3/Nb$_{2}$3/)O$_3$+2.0 mol%B$_2$O$_3$+10.0 mol%CuO ceramic sintered at 875 $^{\circ}C$ for 2 h.h.2 h.h.
Park, Dong-Bae;Myung, Jae-Woo;Na, Bong-Kwon;Kang, Chan Hyoung
Journal of the Korean institute of surface engineering
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v.46
no.4
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pp.145-152
/
2013
The growth behavior of nanocrystalline diamond (NCD) film has been studied for three different substrates, i.e. bare Si wafer, 1 ${\mu}m$ thick W and Ti films deposited on Si wafer by DC sputter. The surface roughness values of the substrates measured by AFM were Si < W < Ti. After ultrasonic seeding treatment using nanometer sized diamond powder, surface roughness remained as Si < W < Ti. The contact angles of the substrates were Si ($56^{\circ}$) > W ($31^{\circ}$) > Ti ($0^{\circ}$). During deposition in the microwave plasma CVD system, NCD particles were formed and evolved to film. For the first 0.5h, the values of NCD particle density were measured as Si < W < Ti. Since the energy barrier for heterogeneous nucleation is proportional to the contact angle of the substrate, the initial nucleus or particle densities are believed to be Si < W < Ti. Meanwhile, the NCD growth rate up to 2 h was W > Si > Ti. In the case of W substrate, NCD particles were coalesced and evolved to the film in the short time of 0.5 h, which could be attributed to the fact that the diffusion of carbon species on W substrate was fast. The slower diffusion of carbon on Si substrate is believed to be the reason for slower film growth than on W substrate. The surface of Ti substrate was observed as a vertically aligned needle shape. The NCD particle formed on the top of a Ti needle should be coalesced with the particle on the nearby needle by carbon diffusion. In this case, the diffusion length is longer than that of Si or W substrate which shows a relatively flat surface. This results in a slow growth rate of NCD on Ti substrate. As deposition time is prolonged, NCD particles grow with carbon species attached from the plasma and coalesce with nearby particles, leaving many voids in NCD/Ti interface. The low adhesion of NCD films on Ti substrate is related to the void structure of NCD/Ti interface.
Journal of the Institute of Convergence Signal Processing
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v.14
no.3
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pp.191-204
/
2013
In this paper, we investigated the correlation outputs of Daejeon correlator at the viewpoints of the buffer memory setting related to the fine delay tracking and the under/overflow issue in FFT modules, in order to eliminate DC-like component and phase concentration to 0 degree. As the ring buffer memory is being used for the fine delay tracking, the DC-like component in correlation outputs is generated by improper setting of data read/write address, and then that address setting method is modified to exclude a polluted FFT segment in correlation processing when crossing the port/stream boundary. The phase concentration to 0 degree at beginning of bandpass is caused by inadequate scaling factors, which may be the origins of under/overflow occurred at internal computation of FFT stage. With the revised method of the ring buffer memory setting and the scaling factors in FFT, we could obtain higher signal-to-noise ratio and flux density, compared to the previous method, through the correlation processing of true observational data.
Park Seon-Joo;Abn Younjhin;Min Hae Sook;Oh Kyoung Soo;Park Chan;Cho Nam Han;Kim Kuchan
Korean Journal of Community Nutrition
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v.10
no.4
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pp.536-545
/
2005
This study was conducted to investigate osteopenia and osteoporosis prevalence of radius and tibia using Quantitative Ultrasound (QUS) and to identify affecting factors of osteoporosis. A total of 4,340 women aged 40 - 69 years, living in Ansung (rural) and Ansan (mid-sized) area, and free of illnesses affecting bone metabolism participated in the community-based cohort study. Among them 4,059 subjects measured radius bone density and 4,089 measured tibia. The T-score threshold, defined as < -1.0 and $\le$-2.5, was used to identify subjects with osteopenia and osteoporosis by WHO criteria. The crude prevalence of osteoporosis in radius and tibia was $8.4\%$ and $23.3\%$ respectively; after adjustment for age, it changed $6.3\%$ and $18.8\%$. In simple logistic regression analysis, the prevalence of osteoporosis increased by aging, non-marital status, low education, low income. Otherwise, high intakes of Ca/P, thiamin, riboflavin, vitamin B6, and vitamin E were decreased osteoporosis prevalence. Compared to the normal BMI (body mass index) group 08.5 $\le$ BMI < 23), the odds ratio (ORs) of the low BMI group (BMI < 18.5), and high BMI groups (BMl25-30, BMI $\ge$ 30) were significantly increased. The OR of osteoporosis decreased across increasing quartiles of intakes of Ca, P and Ca/P. Therefore, maintaining normal BMI and increasing Ca intake and Ca/P ratio may have a beneficial effect on bone health of Korean women.
Journal of the Korean Society for Marine Environment & Energy
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v.18
no.2
/
pp.81-93
/
2015
The comprehensive master plan in November 2010 on Saemangeum internal development has been released, and there is a need for complementary measures related to in-situ monitoring methods in order to acquire water temperature (T) and salinity (S) data. Thus, these data are monitored and analyzed by Korea Rural Community Corporation continuously. The purposes of current study are to evaluate the distributions of seasonal T and S, sigma-t, and stratification parameter and to compare annual stratification system in 2011 and 2012. To achieve these objectives, monthly vertical changes of T, S, and sigma-t, which are reproduced by a kriging technique, have been analyzed. In summer, the temperature difference between surface and bottom layers varies from 2 to $3^{\circ}C$, and the stratification of T is considerably weak. The stratification of S occurs abruptly within depth of EL. (-)5 to EL. (-)10 m. Therefore, stratification is induced by sudden increasing of water inflow amount due to a localized downpour during the rainy season, and these stratification processes are strongly influenced by inflowing a fresh water from watersheds in estuary environment.
Seismic reflection profile analysis, potential field analysis, and potential field modeling using deep seismic reflection, gravity, magnetic, and geological data were performed to better understand the location and nature of the Grenville Front in Ohio, USA. The seismic reflection profile reveals a broad zone of east dipping basement reflectors associated with the Grenville Front in western Ohio and a broad region of west dipping reflectors cutting through the entire crust in eastern Ohio. Potential field analysis indicates that the Grenville Front is characterized by a gravity low, an associated gravity positive and a magnetic high. The results of the gravity and magnetic modeling using seismic data suggest that the lower crust is thickened at the interpreted position of the Grenville Front and high grade metamorphic rocks make up the Grenville Front Tectonic Zone (GFTZ). The gravity low at the Grenville Front is due to the thickened crust, while the magnetic high is due to high grade metamorphic rocks. The gravity high immediately east of the GFTZ in central Ohio is caused by thrusting of high density lower and middle crustal rocks into the upper crust. There is no compelling evidence that this gravity high is related to a Precambrian rift zone as has been suggested in previous studies.
The most dominant type of landslide in Korea is debris flows which mostly take place along mountain slopes during the rainy season, July to August. The landslides have been reported to begin activation when rainfall is more than 200mm within 2days. The debris flows are usually followed by translational slips which occur upper part of mountain slopes and they transit to debris flow as getting down to the valleys. Lithology, location, slope inclination, grain size distribution of soil, permeability, dry density and porosity have been proved as triggering factor causing translational slides. The triggering data taken from mapping are statistically analysed to get landslide potential quantitatively. Rock mass creeps mostly occur on well bedded sedimentary rocks in Kyeongsang Basin. Although the displacement of rock mass creep is relatively small about 1m, the creep can cause severe hazards due to relatively large volume of the involved rock mass. Examples are rock mass creep occurred in the mouth of Hwangryongsan Tunnel, in Chilgok and in Sachon in 1999. Although the direct factor of the creeps are due to slope cutting at the foot area, more attention is required A rotational slide occurring within thick soil formation or weathered rock is also closely related to bottom part of slope cutting. It is propagated circular or semi-circular type. Especially in korea, the rotational slide may be frequently occurred in Tertiary tuff area. Because they are mainly composed of volcanic ash and pyroclastic materials, well developed joints and high degree of swelling and absorption can easily cause the slide. The landslide among the Pohang-Guryongpo national road is belong to this type of slide.
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