Korean Journal of Community Nutrition (대한지역사회영양학회지)

The Korean Society of Community Nutrition (대한지역사회영양학회)
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Osteoporosis Prevalence of Radius and Tibia and Related Factors Using Multiple Bone Sites Quantitative Ultrasound Measurement of the Korean Health and Genome Study Cohort Women

지역사회 코호트 여성의 요골과 경골에서의 골다공증 유병률과 관련 요인 분석

  • Park Seon-Joo (National Genome Research Institute, National Institute of Health) ;
  • Abn Younjhin (National Genome Research Institute, National Institute of Health) ;
  • Min Hae Sook (National Genome Research Institute, National Institute of Health) ;
  • Oh Kyoung Soo (National Genome Research Institute, National Institute of Health) ;
  • Park Chan (National Genome Research Institute, National Institute of Health) ;
  • Cho Nam Han (Department of Preventive Medicine, Ajou University School of Medicine & Hospital) ;
  • Kim Kuchan (National Genome Research Institute, National Institute of Health)
  • 박선주 (국립보건연구원 유전체연구부) ;
  • 안윤진 (국립보건연구원 유전체연구부) ;
  • 민해숙 (국립보건연구원 유전체연구부) ;
  • 오경수 (국립보건연구원 유전체연구부) ;
  • 박찬 (국립보건연구원 유전체연구부) ;
  • 조남한 (아주대학교 의과대학 예방의학교실) ;
  • 김규찬 (국립보건연구원 유전체연구부)
  • Published : 2005.08.01
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Abstract

This study was conducted to investigate osteopenia and osteoporosis prevalence of radius and tibia using Quantitative Ultrasound (QUS) and to identify affecting factors of osteoporosis. A total of 4,340 women aged 40 - 69 years, living in Ansung (rural) and Ansan (mid-sized) area, and free of illnesses affecting bone metabolism participated in the community-based cohort study. Among them 4,059 subjects measured radius bone density and 4,089 measured tibia. The T-score threshold, defined as < -1.0 and $\le$-2.5, was used to identify subjects with osteopenia and osteoporosis by WHO criteria. The crude prevalence of osteoporosis in radius and tibia was $8.4\%$ and $23.3\%$ respectively; after adjustment for age, it changed $6.3\%$ and $18.8\%$. In simple logistic regression analysis, the prevalence of osteoporosis increased by aging, non-marital status, low education, low income. Otherwise, high intakes of Ca/P, thiamin, riboflavin, vitamin B6, and vitamin E were decreased osteoporosis prevalence. Compared to the normal BMI (body mass index) group 08.5 $\le$ BMI < 23), the odds ratio (ORs) of the low BMI group (BMI < 18.5), and high BMI groups (BMl25-30, BMI $\ge$ 30) were significantly increased. The OR of osteoporosis decreased across increasing quartiles of intakes of Ca, P and Ca/P. Therefore, maintaining normal BMI and increasing Ca intake and Ca/P ratio may have a beneficial effect on bone health of Korean women.

Keywords

References

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