• Journal of Korean Medical classics
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• v.21 no.1
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• pp.123-141
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• 2008

Objective Classification of herbal formulas through the analysis of compositional herb's is a suitable method in the aspects of the effective applications of herbal formulas. However, these classification methods have some problems in dealing with lots of herbal formulas because the estimations of herbal formula's effects are dependent upon one's memory. In this study, we aimed to establish the effective methodology to elicit the classified herbal formula's chart by introducing the DB systems without interfering with non-standard terms. Method : We entered the herbs informations of the composition of herbal formulas into database, made an alias tables of corresponding herbs, and achieved standardization of herb's informations. Using these databases, we made the classified herbal formula's chart according to the presence and the treatment informations of herbs. Results By analyzing the herbal formula into the set of compositional herbal elements, we could systemically express the parents and children herbal formula at once according to search terms. We provided the advanced searching tools entering the name of herbal formula and compositional herb together. Through these searching methods, it is facilitated to grasp the classified herbal formula's chart according to the addition and reduction of compositional herbs in Dong-uibogam(東醫寶鑑) and Bangjehak(方劑學)

• The Korea Journal of Herbology
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• v.31 no.6
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• pp.29-35
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• 2016

Objectives : Blood stasis (BS) is related to be caused by blood circulation and stagnation which are cancer, atherosclerosis and hyperlipidemia in traditional medicine. We extracted 3 kinds of BS formula; Seogakjihwang-tang (SGT), Tonggyuhawlhyul-tang (THT), Hyulbuchukeo-tang (HCT). This study was conducted to investigate whether the 3 kinds of herbal formula extracts have inhibitory efficacy association with anti-adipogenesis. Methods : To investigate the anti-adipogenesis, we used the mouse fibroblast cell line, 3T3-L1 which differentiated into adipocytes in response to insulin, IBMX and dexamethasone (MDI). Cytotoxicity of herbal formula extracts were examined by CCK-8 kit. Intracellular lipid droplets were detected by Oil-Red-O staining. Triglyceride (TG) and leptin were measure using elisa kit. Results : The yield of water extracts was 14.62% (SGT), 21.27% (THT), 20.02% (HCT). Lipid accumulation was reduced significantly by 3 kinds of herbal formula compared to control. Especially, THT and HCT decreased lipid droplet, respectively at all concentration. The TG and leptin were also inhibited by 3 kinds of herbal formula. The IC50 of TG were $280.51{\mu}g/m{\ell}$ (SGT), $52.62{\mu}g/m{\ell}$ (THT), $313.99{\mu}g/m{\ell}$ (HCT). The IC50 of leptin were $348.76{\mu}g/m{\ell}$ (SGT), $164.02{\mu}g/m{\ell}$ (THT), $257.00{\mu}g/m{\ell}$ (HCT). THT was better than other herbal formula on anti-adipogenesis. Conclusion : kinds of herbal formula inhibited adipogenesis in MDI-induced 3T3-L1 adipocytes, as indicated by the significant reduction in TG and leptin concentration without cytotoxicity. Therefore, 3 kinds of herbal formula for BS might act as a therapeutic agent for preventing lipid diseases, such as obesity and atherosclerosis.

• East Asian mathematical journal
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• v.17 no.1
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• pp.135-146
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• 2001

Several families of infinite series were summed recently by means of certain operators of fractional calculus(that is, calculus of derivatives and integrals of any real or complex order). In the present sequel to this recent work, it is shown that much more general classes of infinite sums can be evaluated without using fractional calculus. Some other related results are also considered.

• Proceedings of the KSR Conference
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• 2007.05a
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• pp.1774-1781
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• 2007

In this study, Matsuda's formula, which has been used to evaluate the acting load on the concrete pillar in 2-Arch tunnels, is investigated and a load reduction factor $({\alpha})$, which has been estimated from numerical parametric studies, is proposed for a better design of 2-Arch tunnels in the future. Numerical parametric studies show that the concrete pillar is subjected to a stress concentration on the excavation side during the first tunnel driving and when tunnel excavation is completed, the induced stress on the pillar in a poor quality of ground condition is 1.5 to 1.8 times the stress developed during the first tunnel driving. In addition, the numerical studies indicate that the acting load on the pillar is in the range of $14{\sim}83%$ of the load estimated by Matsuda's formula. From these results, a load reduction factor $({\alpha})$ is determined and it would make 2-Arch tunnel design more economically.

• Journal of Industrial Technology
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• v.26 no.B
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• pp.43-51
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• 2006

Through the result of calculating the deviation between the value calculated from two-dimensional number formula, one-dimensional number interpretation, and curving part water surface type calculation method, we could confirmed that the deviation is reduced more than 50% when we use curving part water surface type calculation method. Also it was confirmed that there occurs the reduction rate of maximum 59% as the result of comparing with one-dimensional number interpretation since the reduction rate of safe room height was 20%, in 500 CMS of flood water quantity when we planted the construction of levee by curving part water surface type calculation method. And therefore, we have confirmed that the curving water surface type calculation method can be used as a simple formula in rivers with water quantity less than 500 CMS that flows in and out in Jess than 90 degree angle.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1998.10a
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• pp.423-430
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• 1998

Elastomeric bearings are frequently used as a means to isolate structural systems from earthquake loadings. The combination of rubber layers and reinforcing steel shims makes the bearings stiff axially but soft laterally The shear flexibility of these short columns can lead to relatively low buckling loads which may be further reduced when high shear strains are simultaneously imposed. The area reduction formula has been proposed to account for the reduction in buckling load due to shear. The result obtained from the formula is presumed to be conservative but the degree of conservatism is unknown. This paper describes a numerical study which aims at determining the effect of high shear strain on the critical load of rubber bearings. The results from the finite element analysis which accounts for both the material and geometric non-linearities are compared against the theoretical results in order to examine the validity of the theoretical formulas.

• Proceedings of the Korea Concrete Institute Conference
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• 1994.10a
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• pp.356-361
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• 1994

From the previous experimental test results, it has shown that shear that shear strength in lightweight concrete beams was about 85% on that in normal concrete beams. It is speculated that shear connectors in composite beams of steel and lightweight concrete associated with the longitudinal shear strength decrease more in strength than those in normal concrete. So this paper, as a study on strength of shear connectors in composite beams of steel and lightweight concrete slabs, has a purpose to compare the strength formula resulted from the push-out test of thirteen solid slab and four deck Plate slab with the established ones, and then to suggest a proper strength formula of the shear connectors. The established strength formula of the shear connectors is prescribed for $P_ps = 0.50A_s . \sqrt{f_C . E_C}$by AISC coed, but from the experimental test results the strength values of the shear connectors in lightweignt concrete slabs shows about 70% on those of the shear connectors in normal concrete slabs by AISC code. Therefore, as a strength formula this paper suggests to multiply the established strength formula by reduction factor$(\varphi=0.7)$.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.8
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• pp.745-752
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• 2009

In robust design, the mean and variance of design performance are frequently used to measure the design performance and its robustness under uncertainties. In this paper, we present the Gauss-type quadrature formula as a rigorous method for mean and variance estimation involving arbitrary input distributions and further extend its use to robust design optimization. One dimensional Gauss-type quadrature formula are constructed from the input probability distributions and utilized in the construction of multidimensional quadrature formula such as the tensor product quadrature (TPQ) formula and the univariate dimension reduction (UDR) method. To improve the efficiency of using it for robust design optimization, a semi-analytic design sensitivity analysis with respect to the statistical moments is proposed. The proposed approach is applied to a simple bench mark problems and robust topology optimization of structures considering various types of uncertainty.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.24 no.1
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• pp.21-27
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• 2014

In this paper, an approximate formula for radiation efficiency of the plate surround by an infinite rigid baffle is studied. The plate is simply supported and one side is in contact with air, while other side with water. By assuming an infinite plate, the fluid loading effect is derived in terms of an effective mass. Based on the observation that the fluid loading effect decreases as frequency increases, the radiation efficiency formula at high frequency, which was originally derived for a plate vibrating in the air, is modified as the approximate formula for a submerged plate. The fluid loading effect is taken into account in the wavenumber of the plate. Comparisons of the approximate formula with the numerical results shows that they match well except the mid-frequency range in which numerical results show many oscillations. In numerically solving the fully coupled equations of motion, fourfold integrals of the impedance coefficients are reduced to single nonsingular integrals, which results in substantial reduction in computing time.

• Journal of Korean Medicine for Obesity Research
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• v.3 no.1
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• pp.1-6
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• 2003

Background: Recently, Obesity has become a social problem in all over the world including Korea. Dietary regulation, exercise and behavior modification therapy are used in the treatment of obesity, but until now, there have been many difficulties in treating it. Objectives: To examine in obese pre-menopausal Korean females the short-term efficacy for weight loss of an herbal formula (Slim-diet). Design: A 6-week longituidinal evaluation of a herbal formula (Slim-diet) in 35 pre-menopausal females (baseline age $31.6\;{\pm}\;6.1$) with body mass index > $25kg/m^2$. Body composition was measured using bioimpedence analysis (BIA) and dual energy X-ray absorptiometry (DXA). Anthropometry was done by same observer. Total cholesterol, total lipid, triglyceride, and LDL-cholesterol were measured. Results: Herbal formula (Slim-diet) treatment produced significant loss of weight (P < 0.001), percent of body fat (P < 0.001, both BIA and DXA) and waist circumference (P < 0.001). It also produced significant reduction of total cholesterol and total lipid levels (P < 0.05).