• Journal of Gastric Cancer
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• 제23권2호
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• pp.355-364
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• 2023

Background: There are no clear guidelines to determine whether to perform D1 or D1+ lymph node dissection in early gastric cancer (EGC). This study aimed to develop a nomogram for estimating the risk of extraperigastric lymph node metastasis (LNM). Materials and Methods: Between 2009 and 2019, a total of 4,482 patients with pathologically confirmed T1 disease at 6 affiliated hospitals were included in this study. The basic clinicopathological characteristics of the positive and negative extraperigastric LNM groups were compared. The possible risk factors were evaluated using univariate and multivariate analyses. Based on these results, a risk prediction model was developed. A nomogram predicting extraperigastric LNM was used for internal validation. Results: Multivariate analyses showed that tumor size (cut-off value 3.0 cm, odds ratio [OR]=1.886, P=0.030), tumor depth (OR=1.853 for tumors with sm2 and sm3 invasion, P=0.010), cross-sectional location (OR=0.490 for tumors located on the greater curvature, P=0.0303), differentiation (OR=0.584 for differentiated tumors, P=0.0070), and lymphovascular invasion (OR=11.125, P<0.001) are possible risk factors for extraperigastric LNM. An equation for estimating the risk of extraperigastric LNM was derived from these risk factors. The equation was internally validated by comparing the actual metastatic rate with the predicted rate, which showed good agreement. Conclusions: A nomogram for estimating the risk of extraperigastric LNM in EGC was successfully developed. Although there are some limitations to applying this model because it was developed based on pathological data, it can be optimally adapted for patients who require curative gastrectomy after endoscopic submucosal dissection.

• 한국산림과학회지
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• 제102권4호
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• pp.506-514
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• 2013

본 연구는 목재산업 클러스터 구축에 있어서 중요한 위치를 차지하고 있는 목재산업화지원센터 설립을 위한 타당성을 검토하였다. 목재산업화지원센터를 설립하기 위해 할인율 3.5%, 투자기간 4년 및 사업운영 16년, 투자비 246억 원을 투자할 경우, 20년간의 순현재가치 합계액은 2,579천 원으로 나타났고, 비용편익비율은 2.51%, 내부수익률은 10.1%로 산정되었다. 또한, 다지역 투입산출모형을 사용하여 파급효과를 검토한 결과, 전라남도 지역 관련산업의 생산유발계수는 1.4345이고 생산유발효과는 약 352.87억 원, 소득유발계수는 0.1655이며 소득유발액은 약 40.7억 원, 고용유발계수는 0.4665와 고용유발효과는 약 1,145명으로 추정되었다. 따라서 공공성이 강한 시설로 단순히 상기 분석을 통해 사업성 시행여부를 결정할 수는 없으나 운영에 따른 자체 발생비용을 운영수입으로 충당할 수 있는 재무적 독립이 가능한 사업으로 판단되었다.

• 한국산림과학회지
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• 제99권6호
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• pp.808-815
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• 2010

본 연구의 목적은 오미자를 새로이 재배하고자 하는 사람들이나 재배면적을 늘이고자 하는 사람들에게 오미자의 경영실태 및 소득과 투자 수익성을 분석하여 투자에 대한 정보를 제공하고자 하는 것이다. 수익성 분석기법으로 IRR, B/C Ratio, NPV를 이용하였다. 오미자 주산단지인 강원도 인제, 경북 문경과 전남 화순 그리고 경남 산청지역의 총 51가구의 오미자 재배농가를 대상으로 2009년 5월부터 9월까지 작업공정별 투입노동 및 자재비 등에 관해 면접방문조사를 실시하였다. 산지가격인 5,000원~6,000원/kg을 바탕으로 kg당 3가지 출하가격 5,000원, 5,500원, 6,000원의 시나리오별 IRR, B/C Ratio 그리고 소득율 등을 구하였다. 할인율은 3.00%를 적용하였다. 그 결과 3가지 시나리오 모두 IRR이 -16.00%, -6.91%, 0.40% 그리고 B/C Ratio가 0.81, 0.89, 0.97로 나타나 투자수익성이 없는 것으로 나타났다. 그러므로 IRR = 3.00%, B/C Ratio = 1.00을 충족하는 오미자 판매가격 6,200원/kg이상이 되어야 수익성이 있다고 판단되며, 이 때의 소득율은 23.9%인 것으로 나타났다.

• Molecules and Cells
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• 제23권2호
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• pp.252-257
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• 2007

Escherichia coli HslVU is an ATP-dependent protease consisting of two heat shock proteins, the HslU ATPase and HslV peptidase. In the reconstituted enzyme, HslU stimulates the proteolytic activity of HslV by one to two orders of magnitude, while HslV increases the rate of ATP hydrolysis by HslU several-fold. Here we show that HslV alone can efficiently degrade certain unfolded proteins, such as unfolded lactalbumin and lysozyme prepared by complete reduction of disulfide bonds, but not their native forms. Furthermore, HslV alone cleaved a lactalbumin fragment sandwiched by two thioredoxin molecules, indicating that it can hydrolyze the internal peptide bonds of lactalbumin. Surprisingly, ATP inhibited the degradation of unfolded proteins by HslV. This inhibitory effect of ATP was markedly diminished by substitution of the Arg86 residue located in the apical pore of HslV with Gly, suggesting that interaction of ATP with the Arg residue blocks access of unfolded proteins to the proteolytic chamber of HslV. These results suggest that uncomplexed HslV is inactive under normal conditions, but may can degrade unfolded proteins when the ATP level is low, as it is during carbon starvation.

• 수산해양기술연구
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• 제48권4호
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• pp.346-351
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• 2012

The fuel cost of fishing lights for squid jigging fishing vessels takes about 30% of total fishing costs and over 65% of total fuel costs, which indicates the necessity of development of cost-reducing and high efficient fishing light system. This study aimed to analyze the economic effectiveness of LED fishing light systems in combination with metal halide lamp for the squid jigging fishery. Analytical results showed that the level of fishing profits of vessels using LED lights could be different with those of vessels using metal halide lights. That is, when a fuel cost could be reduced by 30%, fishing profits of vessels using LED lights might be the same as those of vessels using metal halide lights, and fishing profits of vessels using LED lights could be higher than those of vessels using metal halide lights when a fuel cost could be reduced by 50%.

• 한국조경학회지
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• 제33권3호
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• pp.84-93
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• 2005

The purpose of this study is to analyze the economic feasibility of the construction of a new ecological park, based on the case of a plan in Yeongcheon City. For fulfilling the purpose of this study, questionnaire survey was conducted in Yeongcheon City. Based on the survey data, cost-benefit analysis is conducted. For this study, costs and benefits of the project are estimated. Then, using NPV, IRR, and B/C ratio criteria, cost-benefit analysis for this study is conducted. from the empirical cost-benefit analysis, NPV of the proposed project is estimated at 5,420 million Won, IRR is estimated at 12.16%, and B/C ratio is estimated at 1.44. Thus, it is found that the construction of a new ecological park in this area would be feasible from the economic point of view.

• Journal of Yeungnam Medical Science
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• 제37권4호
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• pp.286-295
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• 2020

Respiratory infections are very common and highly contagious. Respiratory infectious diseases affect not only the person infected but also the family members and the society. As medical sciences advance, several diseases have been conquered; however, the impact of novel infectious diseases on the society is enormous. As the clinical presentation of respiratory infections is similar regardless of the pathogen, the causative agent is not distinguishable by symptoms alone. Moreover, it is difficult to develop a cure because of the various viral mutations. Various respiratory infectious diseases ranging from influenza, which threaten the health of mankind globally, to the coronavirus disease 2019, which resulted in a pandemic, exist. Contrary to human expectations that development in health care and improvement in hygiene will conquer infectious diseases, humankind's health and social systems are threatened by novel infectious diseases. Owing to the development of transport and trading activity, the rate of spread of new infectious diseases is increasing. As respiratory infections can threaten the members of the global community at any time, investigations on preventing the transmission of these diseases as well as development of effective antivirals and vaccines are of utmost importance and require a worldwide effort.

• Current Optics and Photonics
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• 제8권3호
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• pp.246-258
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• 2024

In aerospace and energy engineering, the reconstruction of three-dimensional (3D) temperature distributions is crucial. Traditional methods like algebraic iterative reconstruction and filtered back-projection depend on voxel division for resolution. Our algorithm, blending deep learning with computer graphics rendering, converts 2D projections into light rays for uniform sampling, using a fully connected neural network to depict the 3D temperature field. Although effective in capturing internal details, it demands multiple cameras for varied angle projections, increasing cost and computational needs. We assess the impact of camera number on reconstruction accuracy and efficiency, conducting butane-flame simulations with different camera setups (6 to 18 cameras). The results show improved accuracy with more cameras, with 12 cameras achieving optimal computational efficiency (1.263) and low error rates. Verification experiments with 9, 12, and 15 cameras, using thermocouples, confirm that the 12-camera setup as the best, balancing efficiency and accuracy. This offers a feasible, cost-effective solution for real-world applications like engine testing and environmental monitoring, improving accuracy and resource management in temperature measurement.

• 대한두개안면성형외과학회지
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• 제22권1호
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• pp.17-25
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• 2021

Background: This study aims to report how the practice of plastic surgeons and their attitude was during the first measure period of coronavirus disease 2019 (COVID-19) pandemic. Methods: A survey study was held among members of the Indonesian Association of Plastic Reconstructive and Aesthetic Surgeons during week 5 after the first report of COVID-19. A 10 multiple-choice questions (MCQs) and 1 essay covered key questions on the area of surgery and operating room, clinics, internal meeting, and consultation. The only open-ended question relates to the last MCQ addresses a future "flipped" medical practice. Results: Response rate was 45.6% among 228 members, with 89.4% did no practice or limited their service to emergency and urgent cases only. Only 1.9% kept their official meeting as usual, while the majority modified it. The practice in the operating theatre and clinic were also altered to comply with the measures; with 21.2% from the total respondents only allowed patients with exposure to come for visit after taking 14 days of self-quarantine. Teleconsultation was practiced by 50% of the respondents, while 41.3% agreed and 10.6% disagreed upon the future "flipped" medical practice. Conclusion: In general plastic surgeons have made supportive actions during the pandemic. Surgery was performed with all precautions at the utmost as a reflection of high alert of viral infection. Teleconsultation has been embraced via existing social media. Agreement upon the future "flipped" medical practice is reasonable. All in all, the actions were considered as most relevant.

• The Plant Pathology Journal
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• 제21권2호
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• pp.87-92
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• 2005

The structural differences between healthy and diseasedpanicle necks caused by Pyricularia oryzae were observed using electron-microscope. In the diseased panicle neck, the infection hyphae of the rice blast pathogen grew through the sclerenchymatous fiber tissue and reached to the central internal lacuna. Since the pathogen grew through the sclerenchymatous fiber tissues, the vascular bundle composed with xylem and phloem had been destroyed and finally the nutrients from the leaf and stem were not able to be transported into the grains. Infection of panicle base by the blast pathogen until 20 days after heading caused more than 50% of yield loss in both Jinmibyeo and Chucheongbyeo. There was a positive correlation between incidence of the panicle blast and rice yield losses. The regression equations between incidence of the panicle blast and yield losses were y= -3.61+496.7 ($R^2$=0.70) in Jinmibyeoand y=-3.93+520.2 ($R^2$=0.82) in Juanbyeo. The panicleblast caused deterioration of grain quality. Healthy grain rate was reduced by increase of panicle blast infection.