• Title/Summary/Keyword: rate dependent

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Purification and Characterization of Bacillus subtilis Protoporphyrinogen Oxidase and Pre-equilibrium Behavior During Oxidation of Protoporphyrinogen IX

  • Jeong, Eun-Ju;Han, Ok-Soo
    • BMB Reports
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    • v.34 no.1
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    • pp.39-42
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    • 2001
  • Previous studies indicate that B. subtilis protoporphyrinogen oxidase is poorly inhibited by diphenyl ether herbicides. To better understand the basis of this insensitivity, the enzyme was overexpressed as a soluble protein in E. coli, purified and characterized. The mechanism of oxidation of B. subtilis protoporphyrinogen IX was studied and the enzyme kinetic parameters were determined for protoporpyrinogen IX; $K_m$, and $k_{cat}$ were $6.3\;{\mu}M$ and $0.028\;h-^1$, respectively. The enzyme required flavin adenine dinucleotide as a cofactor and its activity was enhanced by 1 mM n-octylglucopyranoside. The nonenzymatic oxidation rate was dependent on the concentration of protoporphyrinogen IX, suggesting that the reaction involves a pre-equilibrium step followed by a rate-limiting step.

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Numerical studied on consequenses of the ion pumping effect in helicon plasmas (헬리콘 플라즈마에서 이온 펌핑 효과의 영향에 대한 수치적 해석 연구)

  • 조수원;박인호;최성을;권명회
    • Journal of the Korean Vacuum Society
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    • v.8 no.3B
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    • pp.353-360
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    • 1999
  • The global balance model is applied to investigate the transient behavior of the electron density and temperature in helicon plasmas. The power absorption calculated from the solutions of the Maxwell equations is used in solving the power balance equation. A balance model for the neutral gas is also considered to fins its density self-consistently. It is turned out that the numerical results reasonably explain consequences of the ion pumping effect including the occurrence of two distinct modes of pulsed helicon discharge which have been observed experimentally. The behavior of the discharge parameters are fond to be primarily dependent on the power absorption and the gas flow rate, but the pressure controls the electron density and temperature of the final steady state as well as the transient state even with the same flow rate. Finally, it is shown that the electron density virtually the linear relationship between the density and the magnetic field is retained for a higher pressure when the effect of the ion pumping is negligible.

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Optimal Preventive Maintenance Policy with Cost-dependent Improvement Factor (비용 종속적인 개선지수를 고려한 최적 예방보전 정책)

  • Hong, Seok-Soo;Park, Jong-Hun;Lie, Chang-Hoon
    • Journal of Korean Institute of Industrial Engineers
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    • v.36 no.2
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    • pp.108-116
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    • 2010
  • The maintenance of a deteriorating system is often imperfect. Previous studies have shown that the imperfect preventive maintenance (PM) can reduce the wear out and aging effects of deteriorating systems to a certain level between the conditions of as good as new and as bad as old. In this paper, we employ the concept of the improvement factor in investigating two optimal PM policies; failure limit policy and periodic PM policy. We redefine the improvement factor model as a function of the cost of PM, using this concept, we derive the conditions of optimal PM policies and formulate expressions to compute the expected cost rate. Based on this information, the determination of the maintenance policies which minimize the cost rate is examined. Numerical examples for the Weibull distribution case are also given.

A Study on the Oxidation Characteristics of p-Cresol on Pt Anode (백금전극(白金電極)에 의한 파라크레졸의 양극전해(陽極電解) 산화특성(酸化特性))

  • Kim, Hong-Soo;Nam, Jeong-Woo
    • Journal of the Korean Applied Science and Technology
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    • v.7 no.2
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    • pp.47-53
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    • 1990
  • The electrochemical oxidation behavior of p-cresol on platinum anode had been investigated by cyclic voltammetric method for the variation of concentration, scan rate of potential, temperature and pH of electrolyte. The oxidation potential of p-cresol was dependent on the electrolyte until the pH=11.5, but in basic solution over its, it was held at o.40V(vs. SCE). A diffusion was rate determining step of oxidation as irreversible reaction by the transfer atone electron. The current of peak was proportional to concentration of p-cresol until the 0.1N and optimum concentration was found to be about 0.1N. The activation energy was calculated for 5.8kcal/mol from the plot of log $I_l$ vs. 1/T.

Skin Permeation Characteristics of Antihyperlipoproteinemic Agent using Natural Polymer Bases in Rats (천연고분자 기재에 의한 수용성 항고지단백혈증제의 흰쥐 피부투과 특성)

  • Kong, Seung-Dae;Hwang, Sung-Kwy;Jung, Duck-Chae
    • Journal of the Korean Applied Science and Technology
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    • v.17 no.2
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    • pp.126-131
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    • 2000
  • Transdermal therapeutic system(TTS) is often used as the method of drug dosage into the epidermic skin. Natural polymer were selected as ointment material of TTS. We investigated the permeation of natural polymer ointment containing drug in rat skin using horizontal membrane cell model. Permeation properties of materials were investigated for water-soluble drug such as oxiniacic acid in vitro. These results showed that skin permeation rate of drug across the composite was mainly dependent on the property of ointment base and drug. Proper selection of the polymeric materials which resemble and enhance properties of the delivering drug was found to be important in controlling the skin permeation rate. This result suggests a possible use of natural polymer ointment base as TTS of antihyperlipoproteinemic agent.

Numerical evaluation of FRP composite retrofitted reinforced concrete wall subjected to blast load

  • Nam, Jin-Won;Yoon, In-Seok;Yi, Seong-Tae
    • Computers and Concrete
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    • v.17 no.2
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    • pp.215-225
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    • 2016
  • High performance materials such as Fiber Reinforced Plastic (FRP) are often used for retrofitting structures against blast loads due to its ductility and strength. The effectiveness of retrofit materials needs to be precisely evaluated for the retrofitting design based on the dynamic material responses under blast loads. In this study, the blast resistance of Carbon Fiber Reinforced Plastic (CFRP) and Kevlar/Glass hybrid fabric (K/G) retrofitted reinforced concrete (RC) wall is analyzed by using the explicit analysis code LS-DYNA, which accommodates the high-strain rate dependent material models. Also, the retrofit effectiveness of FRP fabrics is evaluated by comparing the analysis results for non-retrofitted and retrofitted walls. The verification of the analysis is performed through comparisons with the previous experimental results.

The Effects of Macrostructure of Discourse Processing (대형구조가 글 애해에 미치는 영향)

  • Cho, Hey-Ja
    • Korean Journal of Cognitive Science
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    • v.2 no.1
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    • pp.51-72
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    • 1990
  • This study investigated the effects of macrostructure on discourse processing. In this study, three different story were employed to form macrostructures on different times, and reading time, sentence verification time and free recall rate were measured as dependent vari- ables. The results showed that forming the macrostructure influenced the reading and verification times and the recall rate. The results were interpreted to indicate that the macrostructure is important to comprehend and recall the stories, and that the story grammars, hierarchies of story schema and causal relation of sentences affect the comprehension and recall through their interaction in macrostructure.

An Analysis on the State-Dependent Nature of DS/SSMA Unslotted ALOHA

  • Park Seong-Yong;Lee Byeong-Gi
    • Journal of Communications and Networks
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    • v.8 no.2
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    • pp.220-227
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    • 2006
  • In this paper, we present a novel approach to analyze the throughput of direct-sequence spread spectrum multiple access (DS/SSMA) unslotted ALOHA system. In the unslotted system, the departure rate of interfering transmissions is proportional to the number of current interferers that can be regarded as the system state. In order to model this state-dependency, we introduce a two-dimensional state transition model that describes the state transition of the system. This model provides a more rigorous analysis tool for the DS/SSMA unslotted ALOHA systems with both fixed and variable packet lengths. Numerical results reveal that this analysis yields an accurate system performance that coincides with the simulation results. Throughout the analysis we have discovered that the state-dependency of the departure rate causes interference averaging effect in the unslotted system and that this effect yields a higher throughput for the unslotted system than for the slotted system when supported by a strong channel coding.

Experimental Study of Rewetting Phenomena

  • Chung, Moon-Ki;Lee, Young-Whan;Cha, Jong-Hee
    • Nuclear Engineering and Technology
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    • v.12 no.1
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    • pp.9-18
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    • 1980
  • Reflood experiments under atmospheric pressure have been conducted with a single heated tube to investigate basically the rewetting phenomena following a LOCA. Experimental conditions are 180cm length of test tube, wall temperature range of 300-80$0^{\circ}C$, coolant flooding rate of 5-30cm/sec. and subcooling of 35-85$^{\circ}C$. Experiments show that the rewetting velocity is dependent on the initial wall temperature of test tube, coolant flow rate and coolant subcooling. It is required to develop the proper method to evaluate the rewetting temperature and the heat transfer coefficient.

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불량조사기계가 있는 순환생산시스템의 성능해석 및 최적제어

  • 한만수;임종태
    • 제어로봇시스템학회:학술대회논문집
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    • 1996.10b
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    • pp.1024-1027
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    • 1996
  • The cyclic production lines have the first machines starved and the last machine blocked due to the lack or the excess of empty pallets in the feedback buffer. A workpiece in the cyclic production lines is transported on a pallet, and the total sum of pallets in the system does not changed during the system operation time. Therefore, the production rate of the cyclic production lines are dependent on the total number of pallets in the system. In this paper, we suggest the performance analysis method for the cyclic production lines with inspection machines and the optimal total number of pallets in the system that maximizes the production rate of the system. Finally, we validate the suggested methods by simulations.

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