• Korean Journal of Adult Nursing
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• v.28 no.6
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• pp.680-690
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• 2016

Purpose: This study was designed to identify knowledge, attitude, environment, and self-efficacy among perioperative nurses in terms of radiation protection and to describe those factors affecting radiation protection behaviors. Methods: The sample was comprised of 128 perioperative nurses who agreed to participate in this descriptive study. Data were collected from a self-administered questionnaire and were analyzed using the t-test, analysis of variance, Mann-whitney U test, Kruskal-Wallis test, Pearson's correlation, and multiple regression analyses. Results: Radiation protection behaviors were significantly different by participant's gender, length of career as a perioperative nurse, educational level and prior experience with radiation protection education. Radiation protection behaviors were significantly correlated with radiation protection environment and self-efficacy in terms of radiation protection behaviors. In the multiple linear regression models, radiation protection environment and self-efficacy on radiation protection behaviors were statistically significant predictors of radiation protection behaviors, which accounted for 50.3% of variance in dependent variable. Conclusion: This study concluded that radiation protective environment in operating room is important to promote radiation protective behaviors and radiation safety management program to enhance self-efficacy is highly recommended.

• Journal of Preventive Medicine and Public Health
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• v.54 no.6
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• pp.431-440
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• 2021

Objectives: The aim of this study was to predict rabies protective behaviors (RPB) based on protection motivation theory (PMT) among fourth-grade students at schools in Chonburi Province, Thailand. Methods: This cross-sectional study was conducted from December 2020 to February 2021. A multistage sampling technique was used for sample selection. The questionnaire was divided into socio-demographic data and questions related to PMT and RPB. Descriptive statistical analysis was conducted using the EpiData program and inferential statistics, and the results were tested using the partial least squares model with a significance level of less than 5%. Results: In total, 287 subjects were included, of whom 62.4% were girls and 40.4% reported that YouTube was their favorite media platform. Most participants had good perceived vulnerability, response efficacy, and self efficacy levels related to rabies (43.9, 68.6, and 73.2%, respectively). However, 54.5% had only fair perceived severity levels related to rabies. Significant positive correlations were found between RPB and the PMT constructs related to rabies (β, 0.298; p<0.001), and the school variable (S4) was also a predictor of RPB (β, -0.228; p<0.001). Among the PMT constructs, self efficacy was the strongest predictor of RPB (β, 0.741; p<0.001). Conclusions: PMT is a useful framework for predicting RPB. Future RPB or prevention/protection intervention studies based on PMT should focus on improving self efficacy and response efficacy, with a particular focus on teaching students not to intervene with fighting animals. The most influential PMT constructs can be used for designing tools and implementing and evaluating future educational interventions to prevent rabies in children.

• Journal of radiological science and technology
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• v.41 no.6
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• pp.581-586
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• 2018

This study was conducted to analyze factors Influencing Protective Behavior against Radiation Exposure using questionnaires for 231 radiological technologists working in Computed Tomography(CT) examination room with high radiation dose in diagnostic radiology field. Statistical analysis of the collected data revealed that the reasons for partially shielding the examination part in the CT scan were the lack of protective equipment, securing of radiation justification, being annoying and maybe not being harm to adults in order. It was also revealed that the variables influencing the protective behavior were protective behavior against radiation harm, self-efficacy, protective environment, organization culture, protective knowledge and protective instrument in order. The higher the radiological protective environment(${\beta}=0.245$) and the lower the radiological protective knowledge(${\beta}=-0.034$), the more influential the protective behavior against radiation harm was. In this study, it was shown that non examination parts were not shielded in the CT scan. Therefore, it is necessary to improve the level of protective environment, to cultivate knowledge to improve the protective behavior against radiation harm and to have an intervention strategy for concrete action.

• Journal of Fisheries and Marine Sciences Education
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• v.26 no.3
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• pp.510-524
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• 2014

The purpose of this study was to investigate the influence of teacher efficacy and collectivistic self-esteem on alleviation of teacher burnout. In order to achieve these research purpose, data were collected from 161 elementary and secondary school teachers using teacher efficacy scale, collectivistic self-esteem scale and psychological burnout scale. Collected data were analyzed using correlation analysis and hierarchical multiple regression. The major results of statistical analyses were as follows: First, generally background variables were significantly associated with burnout and therefore, background variables were controlled in the analysis of teacher efficacy and collectivistic self-esteem. Second, teacher efficacy influenced on the total burnout(38%) and sub-factors which were emotional exhaustion(27.3%), depersonalization(20.7%) and diminished personal accomplishment(36.1%), and collectivistic self-esteem influenced on the total burnout(38.8%) and sub-factors which were emotional exhaustion(27.1%), depersonalization(29.6%) and diminished personal accomplishment(25.1%). Third, the analysis of additional influence of collectivistic self-esteem in addition to the influence of teacher efficacy on teacher burnout revealed additional influence in the alleviation of total burnout(18.2%), emotional exhaustion(13.9%), depersonalization(16.6%) and diminished personal accomplishment(10.3%). These results showed that teacher's collectivistic self-esteem is an important factor in the alleviation of psychological burnout with teacher efficacy which was well known as a protective factor for psychological burnout. Based upon the above results, implications of these results and limitations of this study were discussed.

• Journal of fish pathology
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• v.22 no.1
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• pp.45-52
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• 2009

Zebrafish was firstly applied to an experimental model for scuticociliatosis caused by Philasterides dicentrarchi, a facultative parasitic ciliate in cultured marine fish. The susceptibility of zebrafish to infection of P. dicentrarchi was assessed by intraperitoneal injection of the ciliates, which produced typical symptoms of scuticociliatosis and significant mortality. The potential use of zebrafish as a model to evaluate the vaccine efficacy against scuticociliatosis was analyzed by immunization of zebrafish with the ciliates lysate. Furthermore, the effect of different adjuvants, such as Quillaja saponin (QS), Montanide, and Freund’s incomplete adjuvant (FIA) on the protective efficacy of the vaccine was investigated. Groups of zebrafish injected with QS or Montanide alone showed higher survival of fish against challenge test compared to control fish. The results suggest that adjuvant-mediated enhancement of innate immune responses play important roles in protection of fish against scuticociliatosis. The considerably high survival in the fish immunized with the antigen alone indicates that the ciliate lysate itself is highly immunogenic to zebrafish, which can elicit protective immune responses. The protective potential of the antigen, ciliate lysate, was enforced through combined administration with adjuvants including QS, Montinide and FIA. No or low mortalities in the groups of fish immunized with the antigen plus adjuvants suggests that the adaptive immune responses of zebrafish might be accelerated by the adjuvants or the protective potential of the antigen and adjuvants might synergistically interact. In spite of several shortcomings such as difficulties in sampling of serum and leucocytes enough to routine immunological analyses, zebrafsih might be the most convenient experimental animal for scuticociliatosis.

• Biotechnology and Bioprocess Engineering:BBE
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• v.9 no.6
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• pp.490-494
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• 2004

An efficacy test of PRP (polyribosylribitol phosphate)-TT (Tetanus toxoid) conjugate vaccines was carried out using BALB/c mice as an animal model by inoculating Haemophilus in­fluenzae type b (Hib) with a virulence enhancement factor (VEF). Three administrations of the conjugate vaccines at 2-week intervals elicited a significantly high level of PRP antibodies (P>0.0001). The protective activity of the PRP immunization was challenged with either Hib with iron dextran (Hib/) or with a combination of mucin and hemoglobin (Hibmh) as a VEF. The me­dium lethal dose $(LD_{50})$ for Hibmh and Hibiwas measured as 10 CFU (Colony Forming Unit) and $2.5{\times}10^{8}$ CFU respectively. Each immunized animal was challenged with five or ten times the $LD_{50}$ level of bacteria with a VEF. A significant difference in mortality between the immunized and control mice (P> 0.01) was observed with the Hibmh challenge inoculation but not with the Hibi challenge inoculation. These results show that a combination of mucin and hemoglobin was able to enhance the virulence of Hib in BALB/c mice to cause a lethal infection, thus suggesting that BALB/c mice introduced to this method can be an effective model animal for testing the protective efficacy of H. influenzae conjugate vaccines.

• The Journal of the Convergence on Culture Technology
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• v.8 no.6
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• pp.191-198
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• 2022

This study was to provide education on hand hygiene and personal protective equipment(PPE) to nursing students and to investigate the effects of knowledge, attitude, and self-efficacy. This was a single group, pre-post quasi-experimental design. This study was conducted from October 28 to November 30, 2021 using a structured questionnaire targeting 18 students in the 3rd year of college nursing. Data analyzed by descriptive statistics and paired t-test. As a result of the study, hand hygiene knowledge (t=3.33, p=.004) and PPE knowledge (t= -11.02, p<.001) significantly increased through hand hygiene and PPE education, and attitude toward personal protective equipment (t =-2.76, p=.013) and self-efficacy (t=-3.69, p=.002) all significantly increased. Therefore, based on the results of this study, it is considered necessary to develop a systematic and repetitive hand hygiene and personal protective equipment education program, and it will be used as basic data for program development.

• IMMUNE NETWORK
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• v.12 no.6
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• pp.261-268
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• 2012

Respiratory syncytial virus (RSV) and influenza virus are the most significant pathogens causing respiratory tract diseases. Composite vaccines are useful in reducing the number of vaccination and confer protection against multiple infectious agents. In this study, we generated fusion of RSV G protein core fragment (amino acid residues 131 to 230) and influenza HA1 globular head domain (amino acid residues 62 to 284) as a dual vaccine candidate. This fusion protein, Gcf-HA1, was bacterially expressed, purified by metal resin affinity chromatography, and refolded in PBS. BALB/c mice were intranasally immunized with Gcf-HA1 in combination with a mucosal adjuvant, cholera toxin (CT). Both serum IgG and mucosal IgA responses specific to Gcf and HA1 were significantly increased in Gcf-HA1/CT-vaccinated mice. To determine the protective efficacy of Gcf-HA1/CT vaccine, immunized mice were challenged with RSV (A2 strain) or influenza virus (A/PR/8/34). Neither detectable viral replication nor pathology was observed in the lungs of the immune mice. These results demonstrate that immunity induced by intranasal Gcf-HA1/CT immunization confers complete protection against both RSV and homologous influenza virus infection, suggesting our Gcf-HA1 vaccine candidate could be further developed as a dual subunit vaccine against RSV and influenza virus.

• Journal of the Korea Institute of Military Science and Technology
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• v.25 no.2
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• pp.210-217
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• 2022

Chemical warfare agents(CWA) such as nerve agents and vesicating agents show lethality by skin contamination. Skin protection, therefore, is one of the top priorities to deal with the growing threat from CWA. In an attempt to develop the most effective topical skin protectant(TSP), candidate substances including PFPE(perfluorinated polyether), PTFE(polytetrafluoroethylene), glycerin, and polysaccharides were evaluated in forms of various formulations against nerve agent simulant DMMP(dimethylmethyl phosphonate) penetration. The protective efficacy of the formulation against DMMP penetration was estimated as the onset time of color change of the KM9 chemical agent detection paper. Based on this study, it was found that several PFPE- and glycerin-based formulations exhibit remarkably superior efficacy as a protective cream. This protective cream is expected to be used as TSP for military application after further research.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.3
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• pp.96-107
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• 2020

This study aimed to identify the associated factors of protective behaviors for radiation exposure among some radiology technologists using the Health Belief Model. The subjects of the study were 541 radiology technologists working at hospitals or clinics in Honam Province. Using the SPSS version 18.0 program, data were analyzed using a t-test, ANOVA, Pearson's correlation analysis, and hierarchical multiple logistic regression analysis. To modify the factors, the performance of subjects who had a higher level of education and nuclear medicine rooms were higher than those who worked in simple radiography rooms. The radiation protective behaviors performance of the subjects who had more exercise, medium-level stress, and worked in higher-quality protection facilities was higher. Regarding the personal perceptions, the cues to action (β=.292, p=.0001), and perceived seriousness (β =.075, p=.010) were factors that had effects on the performance of radiation protection behaviors. Regarding the likelihood of action, the benefits (β=.168, p<.0001), self-efficacy (β=.148, p=.007), and the performance of protective behaviors were higher. In conclusion, protection education as a cue to action should be provided to stimulate protective behaviors, and the benefits of protective behaviors should be emphasized. To increase the performance of protection behaviors, self-efficacy should be enhanced, and the subjects are offered appropriate information that helps perceive seriousness.