• 한국식품저장유통학회지
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• 제21권2호
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• pp.254-263
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• 2014

본 연구에서는 백합과에 속하는 덩굴성 관목인 청미래덩굴 70% 에탄올 추출물과 열수 추출물의 항산화 및 항당뇨에 대한 활성을 연구하였다. 총 폴리페놀 함량 과 플라보노이드 함량 측정, 전자공여능, ABTs 소거능, SOD 유사활성능, xanthine oxidase 저해활성, ACE 저해활성, TBARs 측정, PF값 측정 및 ${\alpha}$-glucosidase 와 ${\alpha}$-amylase 의 저해활성을 측정하였다. 그 결과 총 폴리페놀 함량과 플라보노이드 함량은 에탄올 추출물에 함유량이 더 많았으며, 전자공여능, ABTs 소거능, SOD 유사활성능, xanthine oxidase 저해활성, ACE 저해활성, TBARs 측정, PF값 측정 결과 모두 청미래 덩굴 열수 추출물보다 에탄올 추출물의 활성이 우수하였다. 또한 ${\alpha}$-glucosidase 와 ${\alpha}$-amylase 의 저해활성을 측정한 결과 에탄올 추출물의 활성이 열수 추출물보다 우수하였다. 이상의 검증 결과를 종합하여 볼 때 청미래 덩굴의 에탄올 추출물의 항산화 및 항 당뇨 활성이 우수하였고, 차후 항산화 및 항 당뇨 예방물질 소재로서의 활용이 가능할 것으로 판단된다.

• Preventive Nutrition and Food Science
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• 제12권1호
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• pp.35-39
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• 2007

This study was conducted to investigate the effects of soil selenium (Se) supplementation level on Se contents of green tea and milk vetch. Four different concentrations of sodium selenite ($Na_2SeO_3$) solutions (0.0, 3.3, 33.0 and 165.0${\mu}g/mL$) were prepared and one liter of each solution was well mixed with 10 kg of compost (cowpea soil) to give four different levels of Se-containing soil: $T_1$, 0; $T_2$, 33; $T_3$, 330; $T_4$, and 1,650${\mu}g$/100 g soil. Green tea plants and milk vetch were individually cultivated in those soils for 60 days. Se contents of freeze-dried green tea leaves were 6.87, 10.40, 12.04, and 20.19 ${\mu}g/g$, respectively; all of which were significantly different (p<0.05) from the others except for $T_2$ and $T_3$. The results showed that Se-contents of green tea leaves were increased 1.5$\sim$2.9 times as the Se level in the soil increased. Regression equation between Se contents in green tea (Y) and soil Se supplementation level (X) was: Y=0.007X＋8.857. However, Se contents in the milk vetch were increased significantly (p<0.05) more with the same treatments $T_3$ (74 ${\mu}g/g$) and $T_4$ (187$\mu$g/g) in comparison to those at $T_1$ (5.0 ${\mu}g/g$) and $T_2$ (12.0$\mu$g/g). The increases ranged from approximately between 2.4 to 37.4 times that of the control group. Regression equation between Se contents in milk vetch (Y) and soil Se supplementation level (X) was: Y=0.1063X＋15.989. The large difference of Se contents between green tea leaves and milk vetch would be attributed by the difference of protein contents between the 30% or higher protein-content of legumes and 15$\sim$20% protein of shrubs. The present study clearly indicates that green tea leaves and milk vetch can be enriched in selenium by supplementing the soil with Se. Therefore, Se-enriched green tea or milk vetch powder could be utilized as functional foods in Se-fortified green tea drinks or salads, or as food additives to enhance the daily intake of Se.

• 대한의료기공학회지
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• 제18권1호
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• pp.1-26
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• 2018

The objective of this study is to verify the effects of Moosim-Gi-Gong Doinbeop on low back pain targeting low back pain patients hospitalized in Korean medicine hospitals. For the study, 44 adult female and male patients hospitalized with low back pain at M Korean Medicine Hospital and H Korean Medicine Hospital located in Gimpo, Gyeonggi Province were recruited. The subjects had a temperature difference between left and right 湧泉(KI1) of over 0.5℃ through infrared thermographic imaging, and 23 of them were classified in the control group for retrospective analysis based on the test records. Infrared thermographic imaging, X-ray pelvic AP view - standing position, a sit-and-reach test and a VAS survey were employed for detection, and IBM SPSS Statistics 24 for the statistical process. The results were rounded down to three decimal places as in an average±standard deviation, and the significance level was 0.05 to be evaluated significant if p<0.05. The result of the study is as follows: 1. In the comparison between before and after conducting Moosim-Gi-Gong Doinbeop, the meaningful difference was shown in the experimental group in all indicators. But Indicators except for the temperature difference between right and left 湧泉(KI1)(difference between before and after) and In displaced pelvic correction indicators on the X-ray showed a significant difference in the control group. 2. As for the variation widths of the experimental group and the control group, the former showed significant temperature differences between 印堂(EX-HN3) and 關元(CV4) and right and left 湧泉(KI1); difference variations of anteflexion; and changes in PI and In displacement on the X-ray. 3. As for changes in the experimental group according to demographic characteristics, gender, age and degree of obesity did not show significant differences in all indicators. However, those who experienced back pain for more than six months in the experimental group showed the biggest body temperature differences between 印堂(EX-HN3) and 關元(CV4), while other indicators had no significant difference. As a result, patients who received Korean medicine treatment showed relieved back pain and improvement in pelvic correction and sports activity; however, those who got Moosim-Gi-Gong Doinbeop together showed more clearer improvement effects in pelvic correction and sports activity.

• 수산해양교육연구
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• 제28권6호
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• pp.1715-1723
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• 2016

복합 생약재 열수추출물(6종 혼합)을 농도별 기간별로 사료에 흡습시켜 12주 동안 넙치에 급여 후 비특이적 면역 및 질병저항성에 대한 효과를 조사하였다. 복합 생약재 열수추출물의 첨가는 어류 성장에는 아무런 영향을 미치지 않았으며 혈액생화학적인, 결과도 넙치의 생리에는 아무런 영향을 미치지 않았다. 라이소자임 활성은 0.01%의 복합 생약재 열수추출물 농도로 흡습시킨 사료 그룹에서 라이소자임 활성이 증가됨을 알 수 있었다. 복합 생약재 열수추출물의 투여에 따른 넙치 장기의 병리조직에 영향이 없음을 알 수 있었다. 에드와드균의 인위감염에 의한 질병저항성은 0.01% 복합 생약재 열수추출물 농도에서 상대생존율이 높게 나타났다. 이상의 결과를 종합하여 볼 때 넙치에 복합 생약재 열수추출물을 투여시에는 어류의 비특이적 면역력 증강 및 질병 저항성 증강을 나타내는 것으로 사료되었다.

• 사상체질의학회지
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• 제10권2호
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• pp.455-471
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• 1998

1. 연구배경 및 목적 소양인(少陽人) 신정방(新定方)의 하나인 양격산화탕(凉膈散火湯)의 효능(效能)과 활용(活用)에 대한 임상적(臨床的) 연구(硏究)를 통해 사상체질병증(四象體質病證)의 이해(理解)와 방제(方劑)의 운용(運用)에 도움을 주고자 한다. 2. 방법 1997년 3월부터 1998년 2월까지 1년간 동국대학교 분당한방병원 체질의학클리닉에 내원(來院)한 환자들 중 양격산화탕(凉膈散火湯)이 20첩 이상 투여되고 경과관찰(經過觀察)이 가능했던 65명(남자 40명, 여자 25명)을 대상으로 양격산화탕(凉膈散火湯)이 투여된 환자의 특성, 치료효과, 부작용 등에 관하여 조사하고 분석하였다. 3. 결과 소양인(少陽人)의 양격산화탕(凉膈散火湯)은 남녀 구별 없이 모든 연령층에서 사용되었으며, 대상환자들의 주소증은 흉민(胸悶), 수족병(手足病), 운동장애(運動障碍), 구건(口乾), 상열감(上熱感) 등 37종류였다. 치료효과의 분포는 호전이 58.5%, 우수가 12.3%, 별무변화가 29.3%였으며 악화는 없었다. 전신상태(全身狀態)의 특징으로는 설태(舌苔)가 백태(白苔) 또는 황태(黃苔)를 띄거나 간출이상(刊出異常)이 있는 경우가 많았다. 처방(處方)을 활용할 때는 처방의 변경없이 양격산화탕(凉膈散火湯)만을 사용한 경우가 많았으며 병증(病症)에 따라 약물을 증량(增量)하거나 가미(加味)하여 사용하였다. 양격산화탕(凉膈散火湯)의 치료효과(治療效果)에는 약물의 가감유무(加減有無)가 영향을 미쳤으며, 효과발현시간(效果發顯時間)은 연령이 젊을수록 빠른 것으로 나타났다. 부작용으로는 심계(心悸), 복통(腹痛) 및 소화불량(消化不良) 등이 있었다.

• 보건교육건강증진학회지
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• 제18권1호
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• pp.61-78
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• 2001

The purpose of this research was to find out plans to promote the fulfillment of the breast self-examination and breast cancer screening, which is preventive health behavior about women's having breast cancer exam in some part of our country with searching for the primary causes which have an effect on their fulfillment. The subjects of the study were 540 literate volunteers who were of age from 20 to 69 and who visited 8 health centers in Taegu. The survey research was made through questionares in the 8 health centers in Taegu from the 15th to the 30th of September, 1998. Based on Becker's health belief model asking medical staff's opinions with bibliographies, the major findings from the survey was as follow. The fulfillment rate of the breast self-examination and the breast cancer screening was 37.8％(204 subjects), 27.6％ (149 subjects) each. Getting breast self-exam varied significantly depending on subject's age, income of family, religion, occupation and the number of children. As far as the breast cancer screening was concerned, there was remarkably significant difference in accordance with their age, marital status, religion, occupation, income of family, the number of children, ways of nursing and parturition age of the first baby. The subjects in their forties accounted for the highest rate. Based on the fulfillment of the breast self-examination and the breast cancer screening, the average points of all the variables presented from the health belief as well as the points of the susceptibility, seriousness, benefits, knowledge and level of health concern of interest in health were significantly higher than the points of non-fulfillment of them in the statistical analysis whereas the barriers was lower than them. In consequence of the multiple-logistic regression analysis putting the breast self-examination and the breast cancer screening in dependent variables, occupation, knowledge, seriousness, benefits, barriers and cues to action had significant effects on breast self-examination against breast cancer. Looking more attainments, thinking diseases more seriously, feeling more usefulness and there being any patient around with breast cancer led to the higher rate of the breast self-examination against it. On the other hand, feeling more impedition as well as housewives caused the lower rate of it. The breast cancer screening was significantly affected by age, sensitivity, usefulness, impedition and behavior momentum as well. The cases who are older, feeling more sensitivity against breast cancer, more usefulness of the examination and where any patient around, the fulfillment rate was higher. Contrarily the more impedition they felt, the lower the fulfillment rate was. Accordingly, the study of the causes, which have significant effects on the fulfillment of the self-examination and the breast cancer screening in order to find it in an early stage, and the development of health education programs as well as proper education for public health through carrying on campaigns and stepping up public relations must be indispensable.

• 대한약침학회지
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• 제7권1호
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• pp.5-14
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• 2004

Acupuncture has fairly good weight-reducing effect in treating simple obesity due to the neuroendocrine regulation. In this study, the antiobesity effects of herbal acupuncture(HA) with Sang-hwang(phellinus linteus) at Fuai(SP16) were investigated in the rat fed on high-fat(HF) diet. Sang-hwang mushroom has been proven to have anti-carcinogenic effects and Sang-hwang extracts are highly effective in treatment and preventive treatment of AIDS, diabetes and high blood-pressure. To determine whether the Sang-hwang herbal acupuncture may have the anti-obesity effect, male Sprague-Dawley(4-wk-old) rats were fed a HF diet for 5 wk, which produced significant weight gain compared to rats were fed a normal diet, and then herbal acupuncture were treated for 3 wk in HF diet group. The body weight, food consumption, food effeciency ratio(FER), body fat mass, plasma nitric oxide(NO) were investigated in rats fed on normal diet, HF diet, and HF diet with HA(HF-diet-HA) groups. NO has been proposed to be involved in the regulation of food intake. In addition, the expression of appetite peptides such as orexigenic peptide neuropeptide Y(NPY) and the anorectic peptide cholecystokinin(CCK) were observed in the hypothalamus. HF-HA group reduced body weight gain, FER, body fat contents and NO concentration compared to HF diet group. The expression of NPY was reduced in arcuate nucleus(ARC), and CCK was increased in the paraventricular nucleus(PVN) after treatment of HA. In conclusion, Sang-hwang HA reduced adipocity, plasma NO and hypothalamic NPY, but increased CCK expression in the HF dietinduced obesity rat, therefore HA may have anti-obesity action through regulating body weight and appetite peptide of the central nervous system.

• 한국치위생학회지
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• 제6권4호
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• pp.455-467
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• 2006

Demand for appropriate health care has gradually increased in Korea. In addition, developments of community- and school-based oral health programs have also focused oral health care for the oral health promotion. Especially, school-based oral health programs are the underpinnings of promoting oral health and preventing oral diseases among schoolchildren. School-based oral health programs have had three major components: oral health education, oral health services, and a healthful environments. These included oral health education(one-to-one communication, group communication, and use of mass communication), oral examination, fluoride mouthrinsing, pit-and-fissure sealants, fluoride gel application, mechanical plaque control, and chewing xylitol candy. In this study, we evaluate the effects of oral health programs among primary schoolchildren by comparing the oral health knowledge, oral health behaviors, and perception of caries prevention procedures. Data for this study were obtained from 699 primary schoolchildren at the two primary school in Daegu, Korea. One is experimental group, N primary school, that was established school-based oral health center under supervision of Nam-gu Public Health Center, the other is control group, N' primary school, that was yet to establish school-based oral health center. We surveyed children's oral health knowledge and behaviors, and perception of caries prevention procedures using self-administrated questionnaire and then analyzed differences of each item among two groups. The brief findings of this study were summarized as follows. There are several advantage to a comprehensive school-based oral health program. (1) School-based oral health programs facilitate and increase the effectiveness of teaching oral health subjects. (2) Schoolchildren are available for prevention or treatment procedure. (3) School-based oral health center may be less threating than private dental clinic. (4) With comprehensive school-based oral health programs the decayed, missing, and filled teeth(DMFT) of schoolchildren should demonstrate a substantial and steady decrease over time(Choi et al, 2004). In conclusion, treatment is not the answer to solving children's oral health programs; rather primary prevention is the key. Many countries and communities are focusing on hoe millions of underprivileged children can be provided with health care. Schoolchildren gain the knowledge and behaviors to attain and maintain good oral health in schools. For these reasons, the role of school-based oral health center is not only important but also a necessity.

• 한국환경농학회지
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• 제34권1호
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• pp.46-51
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• 2015

본 연구는 친환경 유기농 살균제로 사용되고 있는 유황자재의 인삼탄저병 방제에 대한 효과와 약해가 발생하지 않는 적정 함량을 조사하는데 목적을 두고 있다. Colletotrichum gloeosporioides균에 의해서 발생하는 탄저병은 인삼의 수확량을 급격하게 감소시키는 파괴적인 병이다. 0.06% 황토유황합제와 0.13% 발효황토유황합제를 2년근 인삼에 처리를 했을 때 어떤 약해현상을 찾아 볼 수 없었다. 친환경자재의 치료효과를 알아보기 위해 탄저균을 접종 후에 다양한 친환경자재들을 처리했다. 석회유황합제(400배액)이 가장 높은 방제효과를 보였고 그다음은 발효황토유황합제(20배액), 발효황토유황합제(40배액), 석회유황합제(400배액) 순으로 높았다. 반면에 예방효과를 측정하기 위해서 병원균 접종 전 친환경자재들을 먼저 처리를 했다. 이 경우에는 발효황토유황합제(40배액)이 가장 높은 방제를 보였고 또한 대조구로 사용했던 기존농약과 비슷한 방제효과를 보였다. 그러므로 발효황토유황합제는 인삼탄저병을 방제하는 친환경 살균제로 사용할 수 있을 것으로 생각 된다.

• 한국가축번식학회지
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• 제15권1호
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• pp.15-22
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• 1991

젖소에 있어서 selenium과 vitamin E투여가 後産停滯 예방에 효과가 있는지를 규명코자 忠南地域에서 飼育하고 있는 젖소를 대조구, Se 單獨區, vit.E單獨區, vit.E 3회구, Se와 vit.E 1회 倂用區 및 Se와 vit.E 3회 倂用區의 6개로 나누어 50mg의 selenium과700IU의 vit.E를 分晩豫定日 21일전에 주사하였으며 vit.E 3회구는 14일과 7일전에 추가로 주사하였다. 12시간 이내에 후산이 만출되지 않는 개체는 後産停滯로 판단하였으며, 後産停滯 發生率, 繁殖效率 및 産乳量을 조사하였던 바 다음과 같은 결과를 얻었다. 1. 後産停滯의 발생율에 있어서 Se이나 vit.E의 단독구와 vit.E 3회구는 예방효과가 없었으나 Se과 vit.E 1회 倂用區는 7.1%로 나타나 대조구 25.6%보다 유의적(P<0.05)인 예방효과를 나타내었다. 2. 次期 繁殖效率에 있어서 분만후 첫 수정시까지의 기간, 공태기간 및 수태당 수정회수는 대조구와 처리구간에 유의적인 차이가 없었으며 차기 産乳量도 대조구와 처리구간에 유의적인 차이가 없었다.