• Interdisciplinary Bio Central
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• v.4 no.1
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• pp.1.1-1.7
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• 2012

Background: The F-box proteins represent one of the largest families of proteins in eukaryotes. Apart from being a component of the ubiquitin (Ub)/26 S proteasome pathways, their regulatory roles in other cellular and developmental pathways have also been reported. One interesting feature of the genes encoding the proteins of this particular family is their variable selection patterns across different lineages. This resulted in the presence of lineage specific F-box proteins across different species. Findings: In this study, 48 non-redundant F-box proteins in E. siliculosus have been identified by a homology based approach and classified into three classes based on their variable C-terminal domains. A greater number of the F-box proteins have domains similar to the ones identified in other species. On the other hand, when the proteins having unknown or no C-terminal domain (as predicted by InterProScan) were analyzed, it was found that some of them have the polyglutamine repeats. To gain evolutionary insights on the genes encoding the F-box proteins, their selection patterns were analyzed and a strong positive selection was observed which indicated the adaptation potential of the members of this family. Moreover, four lineage specific F-box genes were found in E. siliculosus with no identified homolog in any other species. Conclusions: This study describes a genome wide in silico analysis of the F-box proteins in E. siliculosus which sheds light on their evolutionary patterns. The results presented in this study provide a strong foundation to select candidate sequences for future functional analysis.

• Journal of IKEEE
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• v.8 no.2 s.15
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• pp.186-194
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• 2004

Due to the exponential growth of information on the internet, it is getting difficult to find and organize relevant informations. To reduce heavy overload of accesses to information, automatic text classification for handling enormous documents is necessary. In this paper, we describe structure and implementation of a document classification system for web documents. We utilize SVM for documentation classification model that is constructed based on training set and its representative terms in a directory. In our system, SVM is trained and is used for document classification by using word set that is extracted from information and communication related web documents. In addition, we use vector-space model in order to represent characteristics based on TFiDF and training data consists of positive and negative classes that are represented by using characteristic set with weight. Experiments show the results of categorization and the correlation of vector length.

• The Journal of the Korea Contents Association
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• v.15 no.7
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• pp.353-367
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• 2015

From the era of feature phone to the current smart phone which bloomed Social Network Games(SNGs), mobile games have held the top position as killer contents of mobile market. Mobile game has many constraints such as specification of device, network status, and external environment. Based on common perspective of game research, these factors have negative influences on flow of user. Even with these opinions, most mobile gamers have felt satisfaction. To explain this phenomenon, our research focuses on the constraints. Referring to theoretical concepts, we attempt to clarify the relationship between game features and flow through survey methodology. Our finding shows that the constraints have a positive effect on flow even though it disaccords with previous studies. Therefore, we argue that users of mobile game have sense of satisfaction not a cognitive overload as discomforts.

• The KIPS Transactions:PartB
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• v.17B no.1
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• pp.93-98
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• 2010

In this paper, we introduce a system that summarizes product evaluation through linguistic analysis to effectively utilize explosively increasing product reviews. Our system analyzes polarities of product reviews by product features, based on which customers evaluate each product like 'design' and 'material' for a skirt product category. The system shows to customers a graph as a review summary that represents percentages of positive and negative reviews. We build an opinion word dictionary for each product feature through context based automatic expansion with small seed words, and judge polarity of reviews by product features with the extracted dictionary. In experiment using product reviews from online shopping malls, our system shows average accuracy of 69.8% in extracting judgemental word dictionary and 81.8% in polarity resolution for each sentence.

• Reproductive and Developmental Biology
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• v.31 no.1
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• pp.49-53
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• 2007

Astaxanthin is a kind of carotenoid compounds, having a antioxidant and anti-inflammatory activities. The antioxidative mechanism by which carotenoid scavenge free radicals has been clearly elucidated, but has not tried for the development of mammalian preimplantation embryo. This study was conducted to investigate the antioxidative effect of astaxanthin on in vitro development of porcine in vitro fertilized embryos. Porcine embryos derrived from in vitro fertilization (IVF) were cultured in 5% $CO_{2} in air at $38.5^{\circ}C$ in PZM-3 medium supplemented with different dosages of astaxanthin ($0,\;1,\;5\;and\;10{\mu}M$) and taurine (0, 1, 2.5 and 5 mM) as a positive control, and execute to compare the effects of various antioxidants such as taurine, melatonin and asculatin on in vitro development. The proportions of embryos developed to the blastocyst stage were increased when $1\;and\;5\;{\mu}M$ of astaxanthin (26.6 and 23.4%, respectively) and 1 and 2.5 mM taurine (25.8 and 26.4%, Respectively) were supplemented, compared to controls (p<0.05). Also, various antioxidant-treated groups were significantly higher rates of blastocysts (astaxanthin, 27.4%; taurine, 29.1%; melatonin, 26.8%; aesculetin, 27.9%, respectively) than control (18.8%). There was no difference in mean cell number of blastocysts between antioxidants and control. This result indicates that astaxanthin has an antioxidant feature when porcine IVF embryos were cultured in vitro.

• Genomics & Informatics
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• v.2 no.3
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• pp.121-125
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• 2004

The purpose of this study was to investigate the use of decision tree for the classification of antimicrobial peptides. The classification was based on the activities of known antimicrobial peptides against common microbes including Escherichia coli and Staphylococcus aureus. A feature selection was employed to select an effective subset of features from available attribute sets. Sequential applications of decision tree with 17 nodes with 9 leaves and 13 nodes with 7 leaves provided the classification rates of $76.74\%$ and $74.66\%$ against E. coli and S. aureus, respectively. Angle subtended by positively charged face and the positive charge commonly gave higher accuracies in both E. coli and S. aureusdatasets. In this study, we describe a successful application of decision tree that provides the understanding of the effects of physicochemical characteristics of peptides on bacterial membrane.

• The Journal of Korean Academic Society of Nursing Education
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• v.12 no.1
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• pp.43-51
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• 2006

Purpose: This study was performed to identity the relationship between PMS and menstrual attitudes. Method: Data were collected from 417 female college students in Seoul and Gyeonggi-do area during the period from the 6th of September to the 15th of October in 2004. Collected data were analysed using the SPSS WIN 11.0. Result: The results of this study were as follows: 1) Perceived subjective symptoms were clustered endogenous depressive feature($2.76{\pm}.97$), anxiety($2.76{\pm}1.09$), and impulsivity($2.72{\pm}1.02$). 2) PMS was significantly different according to the general characteristics of grade(F=3.414, p=.018), major(F=2.755, P=.004), menarche age(F=5.910, p=.003), pain(F=7.886, p=.000), family history(F=5.366, p=.005). 3) Menstrual attitudes was significantly different according to the general characteristics of grade(F=3.315, p=.020), major(F=3.813, P=.000), religion(F=6.313, p=.000), interval of menstruation(F=2.834, p=.016), pain(F=3.059, p=.048), family history(F=3.062, p=.048). 4) Menstrual attitudes and PMS were in a positive correlation with each other (r=.112, p=.002). Conclusion: This results showed that there is a significant correlation between PMS and menstrual attitudes. For further research, it is recommended to identity major factors affecting PMS and the relationships between them and various subjects.

• Tuberculosis and Respiratory Diseases
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• v.80 no.1
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• pp.60-68
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• 2017

Background: Mucus hypersecretion from airway epithelium is a characteristic feature of airway inflammatory diseases. Tumor necrosis factor ${\alpha}$ (TNF-${\alpha}$) regulates mucin synthesis. Glucocorticoids including mometasone fuorate (MF) have been used to attenuate airway inflammation. However, effects of MF on mucin production have not been reported. Methods: Effects of MF and budesonide (BUD) on the phorbol-12-myristate-13-acetate (PMA)-induction of mucin and TNF-${\alpha}$ in human airway epithelial cells (NCI-H292) were investigated in the present study. Confluent NCI-H292 cells were pretreated with PMA (200 nM) for 2 hours. Subsequently, the cells were stimulated with MF (1-500 ng/mL) or BUD (21.5 ng/mL) for 8 hours. Dexamethasone ($1{\mu}g/mL$) was used as the positive control. Real-time polymerase chain reaction was used to determine MUC2 and MUC5AC mRNA levels. The level of total mucin, MUC2, MUC5AC, and TNF-${\alpha}$ in culture supernatants were measured using enzyme-linked immunosorbent assay. Results: MF and BUD significantly suppressed MUC2 and MUC5AC gene expression in PMA-stimulated NCI-H292 cells. The inhibitory effects of the two steroid drugs were also observed in the production of total mucin, MUC2 and MUC5AC proteins, and TNF-${\alpha}$. Conclusion: Our findings demonstrated that MF and BUD attenuated mucin and TNF-${\alpha}$ production in PMA-induced human airway epithelial cells.

• Parasites, Hosts and Diseases
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• v.21 no.2
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• pp.157-166
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• 1983

In an attempt to clarify the epidemiological feature of C. sinensis in Mangyeong riverside area, the prevalence of clonorchiasis, infestation rate of the cercariae in Parafossarulus manchouricus, and detection rate of the metacercariae in fresh-water fishes were investigated from March 1 to September 30, 1983 at the upper, middle and lower reaches of the river. The results obtained were summarized as follows : 1. Detection rate of C. sinensis egg among inhabitants was 8.2% out of a total of 1,266 personsr, but the differences in detection rates were not statistically significant among upper, middle and lower reaches. According to sect, the detection rates were 10.3% in male and 6.1% in female (p<0.05), but by age groups, increases of the rates were observed as increase in age (p<0.05). 2. Out of a total of 380 fresh-water fishes of 32 different species, 93 fishes (25%) of 12 species were found positive with Clonorchis metacercariae, and there were differences in infection rates of the metacercariae among the fishes in 3 parts of the river; 11% in upper, 35% in middle, and 34% in lower reaches respectively. The metacercarial detection rates from various fishes were 97% in Pseudorasbora larva, Cultriculus eigenmanni (85%) , Gnathepogon strigatus (67%), Microphysogobio yaluensis (50%), Gnathopogon coreanus (47%), Pungtungia hergi (44%), Abbotting riwularis (40%), Moroco oxycephalus (33%), Coreoleuciscus splendidus (32%), Gnathepogon majimap (26%), Rhodeus ocellatus (7%), and Aphyocypris chinensis (3%) respectively. 3. Although very few p. manchouricus were collected at upper reach, 12 snails (0.7%) among a total of 1,713 were found infected with Clonorchis cercariae. Also the cercariae of Echinochasmup iapenicus (7.99%), Lexogenes liberum (0.99%), Cyathocotyle orientalis (0.75%), Esorchis oviformis (0.23%) and Asymphylodora japonica (0.05%) were detected from the snails.

• Journal of the Korean Society of Clothing and Textiles
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• v.33 no.10
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• pp.1665-1672
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• 2009

This study examines the comfort of outdoorwear by electrocardiogram (ECG) and electroencephalogram (EEG) analyses. An experiment that consisted of rest (30 min), exercise (30 min), and recovery (20 min) periods was administered in a climate chamber with 10 healthy male participants. Two kinds of outdoorwear made of 100% cotton fabrics ('Control') and specially engineered fabrics having the feature of quick sweat absorbency and high speed drying fabric ('Functional') are evaluated in the experiment. ECG and EEG signals were obtained during the rest and recovery periods for the two outdoorwear conditions. The ECG analysis identified a smaller decrement of high frequency (HF) power for the 'Functional' when compared with the 'Control' during the recovery period. Next, the EEG analysis showed that the relative band powers of slow $\alpha$ and mid $\alpha$ increased for the 'Functional' while they decreased for the 'Control' and that the ratio of $\alpha$ power to high $\beta$ power was higher for the 'Functional'. The evaluation results indicate that the participants could remain relaxed more with less stress while wearing the functional outdoorwear that demonstrated the positive effects on autonomic nervous system (ANS) activities. The present study is significant in regard that use of ECG and EEG for the assessment of wear comfort is the first in the field of clothing and textile.