• Parasites, Hosts and Diseases
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• 제56권3호
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• pp.215-227
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• 2018

Along with globalization of traveling and trading, fish-borne nematodiases seems to be increasing in number. However, apart from occasional and sporadic case reports or mini-reviews of particular diseases in particular countries, an overview of fish-borne nematodiasis among travelers have never been performed. In this review, we gathered fish-borne nematodiasis among travelers for recent 25 years by an extensive global literature survey using appropriate keywords, e.g. travelers diseases, human infection, anisakiasis, gnathostomiasis, capillariasis, sushi, sashimi, ceviche, Gnathostoma, Pseudoterranova, Anisakis, Capillaria, etc., as well as various combinations of these key words. The Internet search engines PubMed, Medline, Google and Googler Scholar were used as much as possible, and the references of every paper were checked in order to identify useful and reliable publications. The results showed unexpectedly high incidence of gnathostomiasis and low incidence of anisakidosis. The different incidence values of the infection with several fish-borne zoonotic nematode species are discussed, as well as some epidemiological aspects of the infections. The difficulties of differential diagnosis in non-endemic countries are emphasized. It is concluded that travelers must avoid risky behaviors which can lead to infection and that physicians and health authorities must advice travelers on the risks of eating behaviors during travel.

• 한국한의학연구원논문집
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• 제13권2호통권20호
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• pp.37-45
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• 2007

Background : The 'Korean Medicine' is the traditional medicine in Korea, which has preserved its homogeneous quality in the long historic period. But since 1945 when Korea was divided, the Korean Medicine has also been independently developed in South and North Korea. As a Result, it has lost its national homogeneity. Objective : In order to illuminate the past and an actuality of the transition and medical system of traditional medicine in North Korea. Method : Overview a preceding research paper and the various data of traditional medicine in North Korea. Result : 1. The name of North Korea traditional medicine from 'East medicine' was changed history with 'Korean medicine', It with the method which combines a traditional medicine and a Western medicine is endeavoring to modernization. 2. The administrative systems which take charge of the traditional medicine of North Korea are the organization which manages the Korean medicine and the Bureau of The Korean medicine production control. Also there is relation of the Bureau of the treatment prevention. 3. There are 8 medical colleges other than P'yongyang medical college. There is 6 years 6 months and 7 years 7 month follows in curriculum. Conclusions : It evaluated the past and an actuality of the transition and medical system of traditional medicine in North Korea.

• BMB Reports
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• 제56권1호
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• pp.10-14
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• 2023

Organoids derived from stem cells or organ-specific progenitors are self-organizable, self-renewable, and multicellular three-dimensional (3D) structures that can mimic the function and structure of the derived tissue. Due to such characteristics, organoids are attracting attention as an excellent ex vivo model for drug screening at the stage of drug development. In addition, since the applicability of organoids as therapeutics for tissue regeneration has been embossed, the development of various organoids-based regenerative medicine has been rapidly progressing, reaching the clinical trial stage. In this review, we give a general overview of organoids and describe current status and prospects of organoid-based regenerative medicine, focusing on organoid-based regenerative therapeutics currently under development including clinical trials.

• Clinical and Experimental Pediatrics
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• 제50권7호
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• pp.613-621
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• 2007

Hematopoietic stem cell transplantation (HSCT) has expanded and evolved substantially in the last decades to treat various malignant and nonmalignant diseases. However, the conditioning regimen can lead to transplantation related death by major organ dysfunction, severe infection and bleeding. In the allogeneic setting, graft versus host disease may also develop, making post-transplant management complex. To overcome these problems, new stem cell sources, stem cell mobilizing agents and new skills, nonmyeloablative stem cell transplantation including reduced intensity stem cell transplantation has been introduced in clinical practice, but problems remained so far. Recipients of stem cell transplant may be severely immunocompromised for many months after transplantation. Furthermore, long-term complications (endocrine, metabolic, relapse, second malignancies, etc) can develop. Pediatrician is open called on to participate in the evaluation and consideration of patients for possible transplant and long-term follow-up of HSCT patients. This review is intended as a basic overview of HSCT relevant to general pediatrician.

• Journal of Acupuncture Research
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• 제28권4호
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• pp.57-64
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• 2011

Objectives : The aim of this study is to overview the current status of Cochrane systematic review of acupuncture. Methods : Published Cochrane systematic reviews and protocols for evaluating acupuncture and/or moxibustion were searched by the terms 'acupuncture' and 'moxibustion' in Issue 1, Cochrane Library, 2011. Only reviews or protocols that regarded acupuncture or moxibustion as primary methods of intervention in their reviews were included. Data regarding first author national affiliation, intervention and disease, as well as the number of reviews or protocols that included Korean, Chinese, or Japanese databases in search strategies were obtained. Results : We found 92 hits at screening, and 59 studies were eligible for this review. Included interventions were acupuncture (n=56), auricular acupuncture (n=2), and moxibustion (n=1) for various diseases and conditions. The number of publications of Cochrane systematic reviews or protocols increased gradually from 2002 to 2011. First authors' affiliations were located in China (n=32), Australia (n=8), UK (n=7), Canada (n=4), U.S. (n=4), Germany (n=2), Norway, (n=1) and Korea (n=1). 44, four and four Cochrane reviews adopted Chinese, Korean and Japanese databases, respectively. Conclusions : Search strategies in a substantial number of Cochrane reviews or protocols for acupuncture and moxibustion heavily relied on Chinese databases. Korean databases were underused in existing Cochrane reviews and protocols, and Korean authors were much less involved in the Cochrane systematic reviews or protocols than Chinese authors. Further studies need to be conducted in order to incorporate evidence of acupuncture reported in Korean databases into the Cochrane systematic reviews.

• Molecules and Cells
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• 제39권1호
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• pp.1-5
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• 2016

Peroxiredoxins (Prxs) are a very large and highly conserved family of peroxidases that reduce peroxides, with a conserved cysteine residue, designated the "peroxidatic" Cys ($C_P$) serving as the site of oxidation by peroxides (Hall et al., 2011; Rhee et al., 2012). Peroxides oxidize the $C_P$-SH to cysteine sulfenic acid ($C_P$-SOH), which then reacts with another cysteine residue, named the "resolving" Cys ($C_R$) to form a disulfide that is subsequently reduced by an appropriate electron donor to complete a catalytic cycle. This overview summarizes the status of studies on Prxs and relates the following 10 minireviews.

• Journal of Preventive Medicine and Public Health
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• 제46권3호
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• pp.111-117
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• 2013

This article evaluates the overall current disease burden of North Korea through the recent databases of international organizations. It is notable that North Korea as a nation is exhibiting a relatively low burden from deaths and that there is greater burden from deaths caused by non-communicable diseases than from those caused by communicable diseases and malnutrition. However, the absolute magnitude of problems from communicable diseases like TB and from child malnutrition, which will increase the disease burden in the future, remains great. North Korea, which needs to handle both communicable and nutritional conditions, and non-communicable diseases, whose burden is ever more increasing in the nation, can now be understood as a country with the 'double-burden' of disease.

• 대한한의학회지
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• 제33권4호
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• pp.37-41
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• 2012

Objectives: This study was aimed to establish the clinical features of the patients suffering from hyperhidrosis, who are willing to visit Oriental clinics. Methods: Forty-six patients with primary hyperhidrosis were enrolled in this study classification, body part of perspiration and its severity, and constitutional differentiation were analyzed. Results: 85.1% of patients were 10 to 39 years old. The body part most complained of hyperhidrosis was the hands and feet at 50%. The portion of Teaeumin, Soumin, and Soyangin was 56.6% 21.1%, and 21.7% respectively. Soumin specifically showed a higher frequency of palmar and plantar hyperhidrosis as 90%. The average score of symptoms was $5.1{\pm}1.7$ by a 10-point self- reporting numeric rating scale (NRS). No statistical difference of NRS score was observed regarding gender, Sasang classification, or hyperhidrosis region. Conclusions: This study provides an overview of hyperhidrosis patients visiting an Oriental clinic, and will be helpful in establishing a strategy for the Korean medicine (KM)-based therapeutic development.

• Korean Journal of Acupuncture
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• 제26권4호
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• pp.157-172
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• 2009

Objective : The purpose of this study is to review and summarize the research on a burn. Methods : We reviewed 16 studies about burn which were relative to oriental medicine. We selected those studies from Korean studies Information Service System and Korean Traditional Knowledge Portal. Result : Selected 16 studies were divided into 12 trial articles, 3 case reports and 1 review article. Most of studies reported that oriental medical treatment of burn were effective. Conclusion : Further studies needed for burn and more clinical data would be needed to prove the effects of oriental medical treatment in burn.

• 대한한의학회지
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• 제31권3호
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• pp.128-132
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• 2010

Objectives: This study aimed to review the general features of drug induced liver injury (DILI) and the important factors in consideration of herbal drugs and DILI. Methods: We reviewed general aspects of DILI such as classification, inducible factors, diagnosis methods, prevention, and the status of herbal drug-associated DILI via literature. Results: Besides the drug itself, genetic and environmental factors affect hepatic toxicity. There is a lack of definitive diagnoses of DILI by drugs, including herbal remedies. The possibility of herbal drug-associated DILI is exaggerated, and majority of herbal drug-derived hepatic injury could be easily prevented if Oriental doctors pay attention to this issue. Conclusion: This study can provide Oriental doctors an overview and be helpful in minimizing the episodes of hepatotoxicity in use of herbal drugs.