• 제목/요약/키워드: optical coherence tomography

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Low coherence 특성의 SLD를 이용한 2차원 OCT 영상 구현 (2-D OCT image implementation using low coherence SLD)

  • 정태호;박양하;오상기;김용평
    • 한국광학회:학술대회논문집
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    • 한국광학회 2003년도 제14회 정기총회 및 03년 동계학술발표회
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    • pp.290-291
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    • 2003
  • Optical Coherence Tomography is a new medical dianostic imaging technology which can perform micron resolution cross-sectional or tomograpic imaging in biological tissue. In this paper, we analyze OCT system. And we have 2-dimensional OCT image implementation using low coherence SLD.

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Complex Conjugate Resolved Retinal Imaging by One-micrometer Spectral Domain Optical Coherence Tomography Using an Electro-optical Phase Modulator

  • Fabritius, Tapio E.J.;Makita, Shuichi;Yamanari, Masahiro;Myllyla, Risto A.;Yasuno, Yoshiaki
    • Journal of the Optical Society of Korea
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    • 제15권2호
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    • pp.111-117
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    • 2011
  • Full-range spectral domain optical coherence tomography (SD-OCT) with a 1-${\mu}m$ band light source is shown here. The phase of the reference beam is continuously stepped while the probing beam scans the sample laterally (B-scan). The two dimensional spectral interferogram obtained is processed by a Fourier transform method to obtain a complex spectrum leading to a full-range OCT image. A detailed mathematical explanation of the complex conjugate resolving method utilized is provided. The system's measurement speed was 7.96 kHz, the measured axial resolution was $9.6{\mu}m$ in air and the maximum sensitivity 99.4 dB. To demonstrate the effect of mirror image elimination, In vivo human eye pathology was measured.

Common-path Optical Coherence Tomography for Biomedical Imaging and Sensing

  • Kang, Jin-U.;Han, Jae-Ho;Liu, Xuan;Zhang, Kang
    • Journal of the Optical Society of Korea
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    • 제14권1호
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    • pp.1-13
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    • 2010
  • This paper describes a development of a fiber optic common-path optical coherence tomography (OCT) based imaging and guided system that possess ability to reliably identify optically transparent targets that are on the micron scale; ability to maintain a precise and safe position from the target; ability to provide spectroscopic imaging; ability to imaging biological target in 3-D. The system is based on a high resolution fiber optic Common-Path OCT (CP-OCT) that can be integrated into various mini-probes and tools. The system is capable of obtaining >70K A-scan per second with a resolution better than $3\;{\mu}m$. We have demonstrated that the system is capable of one-dimensional real-time depth tracking, tool motion limiting and motion compensation, oxygen-saturation level imaging, and high resolution 3-D images for various biomedical applications.

Speckle Reduction in the Wavelet Domain for Image with Optical Coherence Tomography

  • Chang, Ju-Wan;Lee, Chang-Su;Na, Ji-Hoon;Paes, Stephane;Lee, Byeong-Ha
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 2005년도 ICCAS
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    • pp.2459-2463
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    • 2005
  • Optical coherence tomography (OCT) is high resolution medical imaging system which is obtaining image inside biological objects with non-destructive method. OCT system is based on Michelson interferometer with a reciprocating mirror in the reference arm and a biological object in the sample arm. The obtained OCT image suffers from a granular or mottled image, called speckle. Speckle is caused by random interferences between reflected coherence waves. In this paper, we propose effective speckle reduction method that uses wavelet transform. With wavelet domain image, sub-windowing and thresholding are performed. Finally, speckle reduction experiments for Misgurnus mizolepis skin and rat eye images are shown.

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광학 영상기를 위한 실시간 영상 신호 처리에 관한 연구 (Video Rate Image Signal Processing for Optical Coherence Tomography)

  • 나지훈;이병하;이창수
    • 제어로봇시스템학회논문지
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    • 제10권3호
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    • pp.239-248
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    • 2004
  • Optical coherence tomography(OCT) is high resolution imaging system which can see the cross section of microscopic organs in the living tissue. In this paper, we analyze the relation between the light source and the resolution of modulated signal in Michelson interferometer. We construct 1-D OCT signal processing hardware such as amplifiers, filters, and demodulate electronic signals from the photo detector. In order to get 2-D OCT image, the synchronization among optical delay line, sample stage and A/D converter is dealt with. In experiments, we verify analog and digital signal processing blocks which apply to the stacks of glasses. Finally we aquire high resolution 2-D OCT image with respect to the onion tissue. We expect that this result can be applied to the medical instrument through performance improvement.

피부결 및 주름 평가에 있어 광학단층영상술(Optical Coherence Tomography, OCT) 활용 연구(Pilot Study) (Evaluation of Skin Texture and Wrinkle Using Optical Coherence Tomography (Pilot Study))

  • 김승훈;안유진;;김필운;정웅규;이해광
    • 대한화장품학회지
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    • 제43권3호
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    • pp.247-254
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    • 2017
  • Optical Coherence Tomography (OCT)는 광 산란과 간섭 현상을 이용하여 비침습적으로 생체조직의 표면 및 내부 구조를 이미지화 할 수 있는 영상기술이다. OCT 기술은 질병의 조기진단과 같은 의료 분야에서 활발히 활용되어 왔으나 미용을 위한 피부진단으로의 적용은 아직 초기단계라 할 수 있다. 본 연구에서는 OCT를 피부효능평가에 도입하여 피부결 및 주름 평가에 활용 가능성을 살펴보았다. 모사판(replica)을 대상으로 한 평가에서 PRIMOS와 유사한 패턴을 보여 주었고 주름을 모사한 3차원 모델을 이용한 평가에서는 PRIMOS에 비해 측정각에 따른 오차가 적음을 확인할 수 있었다. 그리고 커버력 화장품을 이용한 사용 전후의 평가에 있어서도 이를 구분할 정도의 해상도를 보였다. 이러한 평가를 통해 OCT의 미세주름평가에서의 가능성을 알 수 있었고 향후 더 구체화된 연구를 통해 그 활용가능성에 대한 신뢰도를 높일 예정이다.

간섭계 형태에 따른 광단층 촬영장치의 SNR 비교 (Comparison of Signal to Noise Ratios in different configulation of optical coherence tomography systems)

  • 양승국;박양하;장원석;오상기;김현덕;김기문
    • 한국정보통신학회:학술대회논문집
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    • 한국해양정보통신학회 2004년도 춘계종합학술대회
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    • pp.804-806
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    • 2004
  • 인체에 무해하며 고분해능의 단층영상과 저가격 및 소형으로 제작이 가능하여 전세계적으로 많은 연구가 진행중인 광영상 단층촬영기(Optical coherence tomography system : OCT)에 관한 것이다. 샘플에서 흡수와 산란으로 인하여 샘플로부터 반사된 광신호는 매우 미약하다. 게다가 커플러등에 의한 손실로 인하여 광검출기에 도달하는 신호는 매우 미약하다. 이러한 On시스템의 신호대 잡음비를 향상시키기 위하여 기본적인 마이켈슨 간섭계와 마흐젠더 간섭계를 구성하여 시뮬레이션과 기준샘플을 이용하여 측정하였다. 실험결과 마흐젠더 간섭계를 사용한 샘플로 반사된 광신호는 OCT 시스템의 신호대 잡음비 향상시키기 위하여 두 가지 형태의 간섭계를 구성하였으며 시뮬레이션을 통한 비교 분석과 기준 샘플의 측정에 의한 비교분석을 하였다. 실험결과 마흐젠더 간섭계형 OCT 시스템이 신호대 잡음비가 향상됨을 확인 하였다.

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FDML 방식 스위핑 광원을 사용한 SS-OCT 구현 (Realization of Swept Source-Optical Coherence Tomography using FDML Laser)

  • 엄진섭
    • 센서학회지
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    • 제20권1호
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    • pp.46-52
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    • 2011
  • In this paper, the swept source-optical coherence tomography system using frequency domain mode locked(FDML) laser has realized. The FDML swept source laser showed 55.03 kHz sweeping speed, 125 nm sweeping range, and 9 mW output optical power, which are the superiority of FDML laser compared to previous swept source lasers. Also, through the cross-sectional image captured at 5 frames per second for a mirror, a 1 mm-thickness glass plate, and a thumb bottom, the performance of the system has demonstrated.

Partial Spectrum Detection and Super-Gaussian Window Function for Ultrahigh-resolution Spectral-domain Optical Coherence Tomography with a Linear-k Spectrometer

  • Hyun-Ji, Lee;Sang-Won, Lee
    • Current Optics and Photonics
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    • 제7권1호
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    • pp.73-82
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    • 2023
  • In this study, we demonstrate ultrahigh-resolution spectral-domain optical coherence tomography with a 200-kHz line rate using a superluminescent diode with a -3-dB bandwidth of 100 nm at 849 nm. To increase the line rate, a subset of the total number of camera pixels is used. In addition, a partial-spectrum detection method is used to obtain OCT images within an imaging depth of 2.1 mm while maintaining ultrahigh axial resolution. The partially detected spectrum has a flat-topped intensity profile, and side lobes occur after fast Fourier transformation. Consequently, we propose and apply the super-Gaussian window function as a new window function, to reduce the side lobes and obtain a result that is close to that of the axial-resolution condition with no window function applied. Upon application of the super-Gaussian window function, the result is close to the ultrahigh axial resolution of 4.2 ㎛ in air, corresponding to 3.1 ㎛ in tissue (n = 1.35).