• International Journal of Automotive Technology
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• v.6 no.2
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• pp.183-190
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• 2005

During normal operating conditions, a motor vehicle is constantly subjected to a variety of forces, which can adversely affect its straight-ahead motion performance. These forces can originate both from external sources such as wind and road and from on-board sources such as tires, suspension, and chassis configuration. One of the effects of these disturbances is the phenomenon of vehicle lateral-drift during straight-ahead motion. This paper examines the effects of road crown, tires, and suspension on vehicle straight-ahead motion. The results of experimental studies into the effects of these on-board and external disturbances are extremely sensitive to small changes in test conditions and are therefore difficult to guarantee repeatability. This study was therefore conducted by means of computer simulation using a full vehicle model. The purpose of this paper is to gain further understanding of the straight-ahead maneuver from simulation results, some aspects of which may not be obtainable from experimental study. This paper also aims to clarify some of the disputable arguments on the theories of vehicle straight-ahead motion found in the literature. Tire residual aligning torque, road crown angle, scrub radius and caster angle in suspension geometry, were selected as the study variables. The effects of these variables on straight-ahead motion were evaluated from the straight-ahead motion simulation results during a 100m run in free control mode. Examination of vehicle behavior during straight-ahead motion under a fixed control mode was also carried out in order to evaluate the validity of several disputable arguments on vehicle pull theory, found in the literature. Finally, qualitative comparisons between the simulation results and the test results were made to support the validity of the simulation results.

• Bulletin of the Korean Chemical Society
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• v.18 no.6
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• pp.618-622
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• 1997

The polysiloxane-bridged dinuclear metallocenes $[(SiMe_2O)_n-SiMe_2(C_5H_4)_2][(C_9H_7)ZrCl_2]_2$ (n=1 (7), 2 (8), 3 (9)) have been generated as a model complex for the immobilized metallocene at silica surface by treating the respective disodium salts of the ligands with 2 equivalents of $(C_9H_7)ZrCl_3$ in THF. All three complexes are characterized by $^1H$ NMR and measurement of metal content through ICP-MS. It turned out that the values of ${\Delta}{\delta}=[{\delta}_d-{\delta}_p]$, the chemical shift difference between the distal $({\delta}_d)$ and proximal $({\delta}_p)$ protons, for the produced dinuclear compounds (0.47 for 7, 0.49 for 8, and 0.5 for 9) were larger than the Δδ value of the known ansa-type complex holding the same ligand as a chelating one, that is just the opposite to the normal trend. In order to compare polymerization behavior of the dinuclear metallocene with the corresponding mononuclear metallocene, (Cp)$(C_9H_7)ZrCl_2$ was separately prepared. To investigate the catalytic properties of the dinuclear complexes and mononuclear metallocenes ethylene polymerization has been conducted in the presence of MMAO. The polymerization results display the typical activity dependence on polymerization temperature for all complexes. The most important feature is that the polymers from the dinuclear metallocenes represent enormously improved molecular weight compared with the polymer from the corresponding mononuclear metallocene. In addition, the influence of the nature of the bridging ligand upon the reactivities of the dinuclear metallocenes has also been observed.

• Smart Structures and Systems
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• v.16 no.1
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• pp.163-181
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• 2015

This research investigates the structural health monitoring of nonlinear structures after a major seismic event. It considers the identification of flag-shaped or pinched hysteresis behavior in response to structures as a more general case of a normal hysteresis curve without pinching. The method is based on the overall least squares methods and the log likelihood ratio test. In particular, the structural response is divided into different loading and unloading sub-half cycles. The overall least squares analysis is first implemented to obtain the minimum residual mean square estimates of structural parameters for each sub-half cycle with the number of segments assumed. The log likelihood ratio test is used to assess the likelihood of these nonlinear segments being true representations in the presence of noise and model error. The resulting regression coefficients for identified segmented regression models are finally used to obtain stiffness, yielding deformation and energy dissipation parameters. The performance of the method is illustrated using a single degree of freedom system and a suite of 20 earthquake records. RMS noise of 5%, 10%, 15% and 20% is added to the response data to assess the robustness of the identification routine. The proposed method is computationally efficient and accurate in identifying the damage parameters within 10% average of the known values even with 20% added noise. The method requires no user input and could thus be automated and performed in real-time for each sub-half cycle, with results available effectively immediately after an event as well as during an event, if required.

• Journal of Ginseng Research
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• v.45 no.6
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• pp.706-716
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• 2021

Background: Irritable bowel syndrome (IBS), the most common functional gastrointestinal disorder, is characterized by chronic abdominal pain and bowel habit changes. Although diverse complicated etiologies are involved in its pathogenesis, a dysregulated gut-brain axis may be an important factor. Red ginseng (RG), a traditional herbal medicine, is proven to have anti-inflammatory effects and improve brain function; however, these effects have not been investigated in IBS. Methods: Three-day intracolonic zymosan injections were used to induce post-infectious human IBS-like symptoms in mice. The animals were randomized to receive either phosphate-buffered saline (CG) or RG (30/100/300 mg/kg) for 10 days. Amitriptyline and sulfasalazine were used as positive controls. Macroscopic scoring was performed on day 4. Visceral pain and anxiety-like behaviors were assessed by colorectal distension and elevated plus maze and open field tests, respectively, on day 10. Next-generation sequencing of gut microbiota was performed, and biomarkers involved in gut-brain axis responses were analyzed. Results: Compared to CG, RG significantly decreased the macroscopic score, frequency of visceral pain, and anxiety-like behavior in the IBS mice. These effects were comparable to those after sulfasalazine and amitriptyline treatments. Moreover, RG significantly increased the proliferation of beneficial microbes, including Lactobacillus johnsonii, Lactobacillus reuteri, and Parabacteroides goldsteinii. RG significantly suppressed expression of IL-1β and c-fos in the gut and prefrontal cortex, respectively. Further, it restored the plasma levels of corticosterone to within the normal range, accompanied by an increase in adrenocorticotropic hormone. Conclusion: RG may be a potential therapeutic option for the management of human IBS.

• Journal of Engineering Education Research
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• v.24 no.4
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• pp.21-29
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• 2021

The objective of this research is to devise a BARS evaluation system as a performance evaluation plan for non-face-to-face capstone design and to verify the validity through the expert FGI as the remote education is highlighted as a new normal standard in the post corona epoch. The conclusion of this research is as follows. First, the non-face-to-face capstone design is a competency centered subject that allows you to develop the engineering and majoring knowledge and its function and attitude, and the achievement of program outcome is the objective competency, and the researcher proposes the BARS method evaluation, one of competency evaluation method, as a new performance evaluation plan. Second, for the evaluation of PO achievement of non-face-to-face capstone design, the researcher deduced 20 behavior identification standard(anchor) of BARS evaluation system, and developed the achievement standard per 4 levels. Third, as the evaluation tool of non-face-to-face capstone design, the presentation data(PPT), presentation video, product such as trial product(model), non-face-to-face class participation video, discussion participating video, team activity report, and result report for the evidential data of BARS evaluation were appeared as proper. Finally, the BARS evaluation plan of non-face-to-face capstone design would be efficiently made through the establishment of evaluation plan, the establishment of grading standard of BARS evaluation scale, the determination of evaluation subject and online BARS evaluation site.

• Journal of Biomedical Engineering Research
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• v.44 no.1
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• pp.53-63
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• 2023

There have been many studies from the genetic system to physical activity and emotional expression such that there are gender differences. The purpose of this study was to determine how the structural characteristics of cortical thickness differ between males and females. This study used data from the Human Connectome Project (HCP). To analyze age-specific sexual dimorphisms of cortical thickness, selected 8-80 year old subjects were divided into five detailed age range groups according to each criterion. A total of 1,700 individual brain MRI T1 data were registered in stereotaxic space for analysis and classified into white matter (WM), gray matter (GM), and cerebro-spinal fluid (CSF). For surface-based analysis, the WM/GM surface was reconstructed from a spherical polygon model with 40962 vertices per hemisphere, and each vertex was extended to the GM/CSF boundary. Cortical thickness was then measured between each vertex using the t-link method. In the statistical analysis, intracranial volume was used as a covariate to exclude the effect of the difference in brain size of each individual, and the result of using age as a covariate was added to confirm the age effect within each group. Gender differences in cortical thickness had significant results by group. This may be an index to explain diseases with sexual dimorphism in prevalence or become a basis for explaining the characteristics of each sex that appear in behavior, personality, and aging. Therefore, the results of our study could be a criterion for age classification in future studies and for understanding 'normal' sexual dimorphism.

• Journal of the Korean Geotechnical Society
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• v.23 no.3
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• pp.89-100
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• 2007

In the companion paper, we provided the novel elastic-plastic constitutive model based on the micromechanics theory. Herein, the elastic and elastic-plastic deformation of granular soils is meticulously analyzed. To guarantee high accuracy of the microscopic parameter, the systematic procedure to evaluate the parameters is provided. The analysis of the elastic response during the isotropic and triaxial compression shows that the stress-level dependency of cross-anisotropic elastic moduli is induced by the power relationship of the contact force in the normal contact stiffness, while the evolution of fabric anisotropy is more pronounced during triaxial compression. The micromechanical analysis indicates that the plastic strains are likely to occur at very small strains. The plastic deformation of tangential contacts has an important role in the reduction of soil stiffness during axial loading.

• Journal of Veterinary Science
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• v.25 no.3
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• pp.35.1-35.13
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• 2024

Importance: Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis characterized by inflammation within the central nervous system. However, inflammation in non-neuronal tissues, including the lungs, has not been fully evaluated. Objective: This study evaluated the inflammatory response in lungs of EAE mice by immunohistochemistry and histochemistry. Methods: Eight adult C57BL/6 mice were injected with myelin oligodendrocyte glycoprotein_35-55 to induce the EAE. Lungs and spinal cords were sampled from the experimental mice at the time of sacrifice and used for the western blotting, histochemistry, and immunohistochemistry. Results: Histopathological examination revealed inflammatory lesions in the lungs of EAE mice, characterized by infiltration of myeloperoxidase (MPO)- and galectin-3-positive cells, as determined by immunohistochemistry. Increased numbers of collagen fibers in the lungs of EAE mice were confirmed by histopathological analysis. Western blotting revealed significantly elevated level of osteopontin (OPN), cluster of differentiation 44 (CD44), MPO and galectin-3 in the lungs of EAE mice compared with normal controls (p < 0.05). Immunohistochemical analysis revealed both OPN and CD44 in ionized calcium-binding adapter molecule 1-positive macrophages within the lungs of EAE mice. Conclusions and Relevance: Taken together, these findings suggest that the increased OPN level in lungs of EAE mice led to inflammation; concurrent increases in proinflammatory factors (OPN and galectin-3) caused pulmonary impairment.

• Steel and Composite Structures
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• v.51 no.3
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• pp.243-260
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• 2024

Thirteen self-compacting recycled concrete filled aluminium tubular (SCRCFAT) columns were tested under concentric compression loads. The effects of the replacement ratio of the recycled concrete aggregate (RCA) and steel fibre (SF) reinforcement on the structural performance of the SCRCFAT columns were studied. A control specimen (C000) was cast with normal concrete without SF to be reference for comparison. Twelve columns were cast using RCA, six columns were cast using concrete incorporating 2% SF while the rest of columns were cast without SF. Failure mode, ductility, ultimate load capacity, axial deformation, ultimate strains, stress-strain response, and stiffness of the SCRCFAT columns were studied. The results showed that, the peak load of tested SCRCFAT columns incorporating 5-100 % RCA without SF reduced by 2.33-11.28 % compared to that of C000. Conversely, the peak load of tested SCRCFAT columns incorporating 5-100% RCA in addition to 2% SF increased by 21.1-40.25%, compared to C000. Consequently, the ultimate axial deformation (Δ) of column C100 (RCA=100% and SF 0%) increased by about 118.9 % compared to C000. The addition of 2% SF to the concrete mix decreased the axial deformation of SCRCFAT columns compared to those cast with 0% SF. Moreover, the stiffness of the columns cast without SF decreased as the RCA % increased. In contrast, the columns stiffness cast with 2% SF increased by 26.28-89.7 % over that of C000. Finally, a theoretical model was proposed to predict the ultimate loads tested SCRCFAT columns and the obtained theoretical results agreed well with the experimental results.

• Geomechanics and Engineering
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• v.38 no.1
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• pp.15-28
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• 2024

The rapid development of the economy has compelled the widen of highways, and the main challenge of this undertaking lies in the uneven settlement of road embankments. Through field and numerical experiments, this study explores the deformation mechanism of shallow buried pipelines due to road widening. The utilization of Plaxis3D software, which is adapt at simulating complex engineering geological conditions, enables the simulation of the settlement of both the central and right-side road embankments. Comparing with other numerical software such as ABAQUS and COMSOL, Plaxis provided more constitutive models including HS, HSS and Hoek-Brown model. The work concludes that the uneven settlement of road cross-sections is positively correlated with the horizontal distance from the pipeline, with a maximum settlement of 73 mm observed after construction. Furthermore, based on the Winkler's assumption, theoretical settlement and stress calculation methods are established. Results indicate that the maximum difference between the calculated values of this formula and simulated values is 1.9% and 7%, respectively. Additionally, the study investigates the stress and settlement of the pipeline's top under different angles to understand its behavior under various conditions. It finds that with traffic loads applied to the new embankment, a lever effect occurs on the lower pipeline, with the fulcrum located within the central isolation zone, leading to a transition in curve type from "single peak and single valley" to "double peak and single valley." Moreover, the settlement of pipelines on both sides of the central isolation zone and the normal stress of the pipeline's top section are symmetrical.