• Title/Summary/Keyword: negative dependent

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A CENTRAL LIMIT THEOREM FOR GENERAL WEIGHTED SUM OF LNQD RANDOM VARIABLES AND ITS APPLICATION

  • KIM, HYUN-CHULL;KIM, TAE-SUNG
    • Communications of the Korean Mathematical Society
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    • v.20 no.3
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    • pp.531-538
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    • 2005
  • In this paper we derive the central limit theorem for ${\sum}_{i=1}^n\;a_{ni}\xi_i$, where ${a_{ni},\;1\;{\leq}\;i\;{\leq}\;n}$ is a triangular array of nonnegative numbers such that $sup_n{\sum}_{i=1}^n\;a_{ni}^2\;<\;{\infty},\;max_{1{\leq}i{\leq}n}a_{ni}{\rightarrow}0\;as\;n\;{\rightarrow}\;{\infty}\;and\;\xi'_i\;s$ are a linearly negative quadrant dependent sequence. We also apply this result to consider a central limit theorem for a partial sum of a generalized linear process $X_n\;=\;\sum_{j=-\infty}^\infty\;a_k+_j{\xi}_j$.

Cell Cycle and Cancer

  • Park, Moon-Taek;Lee, Su-Jae
    • BMB Reports
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    • v.36 no.1
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    • pp.60-65
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    • 2003
  • Cancer is frequently considered to be a disease of the cell cycle. As such, it is not surprising that the deregulation of the cell cycle is one of the most frequent alterations during tumor development. Cell cycle progression is a highly-ordered and tightly-regulated process that involves multiple checkpoints that assess extracellular growth signals, cell size, and DNA integrity. Cyclin-dependent kinases (CDKs) and their cyclin partners are positive regulators of accelerators that induce cell cycle progression; whereas, cyclin-dependent kinase inhibitors (CKIs) that act as brakes to stop cell cycle progression in response to regulatory signals are important negative regulators. Cancer originates from the abnormal expression of activation of positive regulators and functional suppression of negative regulators. Therefore, understanding the molecular mechanisms of the deregulation of cell cycle progression in cancer can provide important insights into how normal cells become tumorigenic, as well as how cancer treatment strategies can be designed.

LAMMER Kinase Lkh1 Is an Upstream Regulator of Prk1-Mediated Non-Sexual Flocculation in Fission Yeast

  • Park, Yoon-Dong;Kwon, Soo Jeong;Bae, Kyung Sook;Park, Hee-Moon
    • Mycobiology
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    • v.46 no.3
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    • pp.236-241
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    • 2018
  • The cation-dependent galactose-specific flocculation activity of the Schizosaccharomyces pombe null mutant of $lkh1^+$, the gene encoding LAMMER kinase homolog, has previously been reported by our group. Here, we show that disruption of $prk1^+$, another flocculation associated regulatory kinase encoding gene, also resulted in cation-dependent galactosespecific flocculation. Deletion of prk1 increased the flocculation phenotype of the $lkh1^+$ null mutant and its overexpression reversed the flocculation of cells caused by lkh1 deletion. Transcript levels of $prk1^+$ were also decreased by $lkh1^+$ deletion. Cumulatively, these results indicate that Lkh1 is one of the negative regulators acting upstream of Prk1, regulating non-sexual flocculation in fission yeast.

ALMOST SURE MARCINKIEWICZ TYPE RESULT FOR THE ASYMPTOTICALLY NEGATIVELY DEPENDENT RANDOM FIELDS

  • Kim, Hyun-Chull
    • Honam Mathematical Journal
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    • v.31 no.4
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    • pp.505-513
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    • 2009
  • Let {$X_k;k{\in}N^d$} be centered and identically distributed random field which is asymptotically negative dependent in a certain case. In this note we prove that for $p{\alpha}$ > 1 and ${\alpha}$ > ${\frac{1}{2}}$ $E{\mid}X_1{\mid}^p(log^+{\mid}X_1{\mid}^{d-1})$ < ${\infty}$ if and only if ${\sum}_n{\mid}n{\mid}^{p{\alpha}-2}P$($max_{1{\leq}k{\leq}n{\mid}S_k{\mid}}$ > ${\epsilon}{\mid}n{\mid}$) < ${\infty}$ for all ${\epsilon}$ > 0, where log$^+$x = max{1,log x}.

Investigating Product Uncertainties in Online Shopping: Evidence from Kenya

  • Kim, Jae Kyung;Mugwe, Paul Dadson
    • Smart Media Journal
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    • v.6 no.1
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    • pp.39-46
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    • 2017
  • The internet has become an important part of the many aspects of people's daily lives such as work, study, entertainment and in form of electronic commerce, shopping. Electronic commerce is growing rapidly in Kenya. There are many successful business-to-business, business-to-customer and customer-to-customer online shopping companies in Kenya. As a consequence, competition between vendors is intense and, therefore, mitigating the negative effects of high product uncertainty is necessary requirement as it remains a biggest hindrance for success of the online shopping. The purpose of this research is to investigate how online product description, third party product assurance, customer service and website design mitigate the negative impact of high product uncertainty. A questionnaire with 28 items is designed to collect data from online customers. Using multiple regression analysis, the relationship between dependent variable (product uncertainty) and independent variables such as product description, third party assurance, website design and customer service is tested. The result shows that all the independent variables are negatively correlated with dependent variable, which means that product description, third party assurance, website design and customer service can be used by online vendors to lessen the problem of product uncertainty in online markets.

Traffic Accident Models of Domestic Rotary by Day and Nighttime (국내 로터리의 주.야간 교통사고모형)

  • Park, Byung-Ho;Lim, Jin-Kang;Back, Tae-Hun
    • Journal of the Korean Society of Safety
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    • v.27 no.2
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    • pp.105-110
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    • 2012
  • This study deals with the accident models of rotary. The objectives is to develop the models by day and nighttime. In pursuing the above, this study gives particular attentions to collecting the data of geometric structure and accidents of 20 rotaries and developing the Poisson and negative binomial regression models using NLOGIT 4.0. The main results are as follows. First, the numbers of accident of nighttime (1.03 per 1,000 entering vehicles) were analyzed to be very higher than those of day (0.47 per 1,000 entering vehicles). Second, 4 Poisson models which were all statistically significant were developed, in which the dependent variable were both the number of accident and EPDO (equivalent property damage only). Finally, the number of entry/exit ($X_1$) and the number of entering lane ($X_5$) in the models of the number of accident, and $X_1$ in the EPDO models were adopted as the common variables. The variables were analyzed to be all positive to the dependent variables.

The Influence of the Interplanetary Magnetic Field (IMF)-Dependent Ionospheric Convection on the Thermospheric Dynamics

  • Kwak, Y.S.;Ahn, B.H.;Richmond, A.D.
    • Bulletin of the Korean Space Science Society
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    • 2003.10a
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    • pp.34-34
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    • 2003
  • To better understand how high-latitude electric fields influence thermospheric dynamics, we study winds in the high-latitude lower thermosphere using the Thermosphere-Ionosphere-Electrodynamics General Circulation Model of the National Center for Atmospheric Research (NCAR/TIEGCM). In order to compare with Wind Imaging Interferometer (WINDII) observations the model is run for the conditions of 1992-1993 southern summer. The association of the model results with the interplanetary magnetic field (IMF) is also examined to determine the influences of the IMF-dependent ionospheric convection on the winds. The wind patterns show good agreement with the WINDII observations, although the model wind speeds are generally weaker than the observations. It is confirmed that the influences of high-latitude ionospheric convection on summertime thermospheric winds are seen down to 105 km. For negative and positive IMF By the difference winds, with respect to the wind during null IMF conditions, show significantly strong anticyclonic and cyclonic vortices, respectively, down to 105 km. For positive IMF Bz the difference winds are largely confined to the polar cap, while for negative IMF Bz they extend to subauroral latitudes. The IMF Bz-dependent diurnal wind component is strongly correlated with the corresponding component of ionospheric convection velocity down to 108 km and is largely rotational. The influence of IMF By on the lower thermospheric summertime zonal-mean zonal wind is substantial at high latitudes, with maximum wind speeds being 60 m/s at 130 km around 77 magnetic latitude.

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Effects of Personality by Each Sasang Constitution on Sleep (체질별 성격요인이 수면에 미치는 영향)

  • Kim, Sang-Hyuk;Park, Ki-Hyun;Jeong, Kyoungsik
    • Journal of Sasang Constitutional Medicine
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    • v.33 no.3
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    • pp.127-137
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    • 2021
  • Objectives The purpose of this study was to identify the effects of personality by each Sasang constitution on sleep using Positive Affect and Negative Affect Schedule(PANAS) and NEO-personality inventory(NEO-PI). Methods The subjects of this study were 2,078 people who had information on Sasang constitutional type and personality(PANAS, NEO-PI) among the data established at the Korean Medicine Data Center. Sleep time and sleep quality were investigated through self-written questionnaires. Sleep time was collected by hand-writing, and sleep quality was checked on a 4 point Likert scale. Pearson correlation analysis was conducted to see the correlation between personality and sleep in each constitutional type. Logistic regression was performed using personality as independent variables to find out how much personality affects sleep time. In order to find out how much personality affects sleep quality, regression analysis was performed using personality as independent variables. Results & Conclusions Sleep time was hardly affected by personality. As a result of Pearson correlation analysis, sleep time in all subjects did not show a significant correlation with personality. In logistic regression on sleep time as the dependent variable, no statistically significant results were obtained except for the Negative Affect(NA) in Taeeumin. Sleep quality showed a statistically significant correlation with the negative affect(NA), neuroticism(N), extraversion(E), Physical Component Summary(PCS) and Mental Component Summary(MCS). As a result of regression analysis on sleep quality as the dependent variable, neuroticism(N), negative affect(NA), positive affect(PA), and extraversion(E) were found in the factors affecting sleep quality. Besides, how much personality affected sleep quality might differ in each constitution. In all constitutions, sleep quality was affected by N, but the rank of N was different in each constitution. The sleep quality of Soyangin was not affected by E, and the sleep quality of Taeeumin was specifically affected by O.

CONVERGENCE PROPERTIES OF THE PARTIAL SUMS FOR SEQUENCES OF END RANDOM VARIABLES

  • Wu, Yongfeng;Guan, Mei
    • Journal of the Korean Mathematical Society
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    • v.49 no.6
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    • pp.1097-1110
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    • 2012
  • The convergence properties of extended negatively dependent sequences under some conditions of uniform integrability are studied. Some sufficient conditions of the weak law of large numbers, the $p$-mean convergence and the complete convergence for extended negatively dependent sequences are obtained, which extend and enrich the known results in the literature.