• Title/Summary/Keyword: natural history

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Screening of Inhibition Activity of LPS-induced NO Production by Ethanol Extracts from Jeju Island Native Plants and Algae

  • Go, Boram;Hyun, Ho Bong;Yoon, Seon-A;Oh, Dae-ju;Yoon, Weon-Jong;Ham, Young-Min
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.77-77
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    • 2019
  • Herbal medicines have been used as a basic means of clinical trial throughout history, and traditional medicines are targeted to seek functional components. To discover new cosmetic or food ingredients among numerous natural resources from Jeju island, we screened for inhibition activity against nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Although NO formation plays an important role to relax vascular muscles or eliminate tumors, NO produced excessively in inflammatory condition can cause metabolic diseases or inflammatory dysfunctions. Among 52 natural resources ethanol extracts, 5 extracts inhibited NO production over 25% compared to only LPS-treated control at the concentration of $100{\mu}g/mL$. In further study, we try to investigate other bio-activities and the phytochemicals of 5 different extracts as useful ingredients for cosmetics or functional foods.

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Glutaric Aciduria Type I: Overview

  • Kim, Su Jin
    • Journal of mucopolysaccharidosis and rare diseases
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    • v.5 no.1
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    • pp.8-11
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    • 2021
  • Glutaric aciduria type 1 (GA1; OMIM #231670) is a rare autosomal recessive-inherited neurometabolic disorder caused by the deficiency of glutaryl-CoA dehydrogenase (GCDH), which is encoded by the GCDH gene. It results in the accumulation of glutaric acid (GA), 3-hydroxyglutaric acid (3-OH-GA), glutaconic acid, and glutarylcarnitine (C5DC). These metabolites are considered to damage the striatum through an excitotoxic mechanism. The treatments of GA1 known to date are metabolic maintenance treatment based on a low-lysine diet and emergency treatment during acute illness. However, treatment after the onset of neurological symptoms has limited effectiveness and is associated with poor outcomes, and the effect of treatment and disease course after treatment are not good. After the implementation of newborn screening, the incidence of acute encephalopathic crisis fell to 10%-20% with early diagnosis, preventative dietary management, and aggressive medical intervention during acute episodes. Recently, several cohort studies have been published on the natural course and treatment of GA1 patients. This mini review will cover the clinical symptoms, natural history, and treatment of GA1 through a literature review.

Estimation of Dynamic Characteristics of an Offshore Meteorological Tower using Ambient Measurements (상시계측을 통한 해상기상탑의 동적특성 평가)

  • Gyehee Lee;Le Quoc Cuong;Daejin Kwag
    • Journal of Wind Energy
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    • v.14 no.3
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    • pp.91-99
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    • 2023
  • In research conducted on a southwestern Korean offshore meteorological tower, acceleration datasets were gathered over half a year with time-history sensors. To enhance data credibility, a parallel measurement system was used for verification. A model of the tower was configured using beam elements, and with modifications accounting for added stiffness from auxiliary structures. Ground interactions were considered as calibrated springs based on soil layer properties. The tower's dynamic attributes and mass sensitivity were discerned using eigenvalue analysis. The structural natural frequency was consistent, with variations primarily due to new equipment adding approximately 1400 kgs. With free vibration damping assumptions, a damping ratio of roughly 1 % was derived.

An Hwak's Recognition of 'Joseon' and 'Joseon Cheolhak' (안확의 '조선' 인식과 '조선철학')

  • Lee, Haeng Hoon
    • The Journal of Korean Philosophical History
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    • no.50
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    • pp.171-200
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    • 2016
  • The full-scaled study of Joseon conducted by Japan in the 1910s was part of its colonial policy, while the native Joseon studies against it contained political aspiration to recover the national rights and independence. Accordingly, the conceptual meaning of 'Joseon' varied according to its subject of speech. The establishment of modern nation-state failed along with the extinction of Korean Empire, but 'Joseon' was newly discovered within national ideology. It became a historical concept in which the experience of the past and the expectation toward the future could be united. The so-called 'Joseon Studies' was only limited to intellectuals in the academic circle, but 'Joseon' embraced the articulations from more various social agents. Furthermore, it is only natural that 'Joseon Studies' should be interpreted within the historical semantics of 'Joseon', considering the connection between concept and discourse. In his The History of Joseon Civilization, An Hwak encompassed the history from the times of ancient mythology to the contemporary times under the banner of 'Joseon'. Opposing Japanese distortion of history carried out in the name of historical positivism, he idealized Joseon history as comparable to that of the Western democracy. He extended the study of 'Joseon' into culture at large, foreshadowing a kind of Joseon philosophy. In his An Overview of Joseon Philosophical Ideas, the first description of 'Joseon philosophy' as an independent field, he proposed philosophy as one of three sources of pride in Joseon and asserted its uniqueness and originality compared to the West. It was an attempt to grasp the peculiarity of Joseon ideas from a perspective of the history of universal human civilization. He considered 'Jong'(倧) as an ideological foundation held from the ancient to the modern times, and the acceptance of Buddhism and Confucianism as beneficial to 'Joseon philosophy'. The birth of 'Joseon philosophy', the modern transformation of the traditional knowledge system, was an intellectual experiment to apply traditional knowledge to the modern disciplinary classification system.

Making Cultural Products Using Natural Dyed Hanji-Fabric (I) (천연염색 한지직물을 활용한 문화상품 제작 (I))

  • Jung, Jin Soun
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.4
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    • pp.23-27
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    • 2019
  • Korea boasts outstanding cultural heritage accumulated over the 5 thousand-year-long history, but has neglected developing marketable commercial products out of its culture. As a result, despite the fact that Korea had successfully developed internationally well-acknowledged technologies, there isn't any exceptional cultural product that can be marketed globally. Therefore, it is necessary to re-design and commercialize a modern sense using unique materials in traditional culture. Fabrics made by natural dyeing have a low saturation, so they do not need special color harmony, they are natural and comfortable. Therefore, fabrics obtained by natural dyeing are considered to be a very suitable material for cultural product development. In addition, Hanji is a good material that can build a field of art by itself because it has a quality, a profound and elegant feeling. In this study, Hanji-fabric, which is made of excellent Hanji, is used for natural dyeing with. Using the dyed fabrics, the cultural products such as two parasols and a card holder was made and presented.

The Resident Attitude for Preservation and Development of Amenity in Eulsuk Island and Its Downstream Area at Estuary of Nakdong River in Korea (낙동강 하구언 을숙도 및 하류지역의 쾌적 환경 자원의 보전과 개발에 대한 주민의 태도)

  • Ok, Chi-Sang;Lee, Won-Gu
    • Journal of Environmental Impact Assessment
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    • v.4 no.1
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    • pp.65-78
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    • 1995
  • The resident attitude for preservation and development of amenity in Eulsuk island and its downstream area at estuary of Nakdong river in Korea were investigated by the questionnaires and the field surveys. Based on the results, the characteristics of this study area are the natural ecological preservation area, natural environmental preservation area and curtural assets for migratory birds. And there are a estuary bank, a Dadae beach and a Molundae park. Special amenities are (1) the light (sunrise, sunset etc), (2) the water(river, sea etc.), (3) the air(fresh wind, beautiful sound etc.), (4) the land space(beautiful view, recreation field, reed area, pine forest etc.) and (5) the stream(dancing of migratory birds, water flow, folk dance, history remains etc.). But at present, the environmental qualities as health, aesthetics safety, amenity and culture are deteriorated by development. So the number of migratory birds are decreasing. The residents desired that in future this area be use for the recreation space, the park and the natural leaning fields etc, as well as the restoration of destroyed resources.

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Genetic Homogeneity of the Korean Native Bumble Bee, Bombus ardens (Hymenoptera: Apidae), Detected by Mitochondrial COI Gene Sequences

  • Yoon, Hyung-Joo;Kim, Sam-Eun;Lee, Myeong-Lyeol;Kim, Iksoo;Bae, Jin-Sik;Sohn, Hung-Dae;Jin, Byung-Rae
    • International Journal of Industrial Entomology and Biomaterials
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    • v.6 no.1
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    • pp.63-68
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    • 2003
  • We investigated the sequence divergence of the geographic samples of the queen bumble bee (Bombus ardens) in Korea. A portion of mitochondrial COI gene sequences (423 bp) was analyzed for 44 individuals collected from seven localities. Sequence analysis resulted in four COI haplotypes with the maximum nucleotide divergence of only 0.5% (two bp). One haplotype (BA1) was dominant in all localities surveyed (86.4%). The finding of low sequence divergence and dominance of one haplotype appear to reflect, although limited, the life history of the B. ardens queens subjected to active dispersal and seasonal fluctuation in queen number.

A Study on Fashion Textile Trend and Characteristics in the 1980s (1980년대 패션에 나타난 텍스타일의 경향과 특징에 관한 연구)

  • 염혜정
    • Journal of the Korean Society of Costume
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    • v.41
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    • pp.117-138
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    • 1998
  • This study can be divied into three major sections: 1. Background on the 1980s : The 1980s can be characterized as a era of rising expectations over the quality of life. Interest in art, history, culture, and new technology increased to appeal to a greater audience. In fashion, these changes led to greater focus on quality and unique stylishness as fashion represented a medium through which luxury and refined tastes could be expressed. 2. Textile Trends of the 80s Divided into 4 Periods : The period of 1980-82 saw the mixture of natural lines with constructive lines. The textiles used in fashions in this period can be characterized by natural materials, mannish materials of the 1950s, feminine materials of the 1920s and 30s, and spoty materials of the 1960s. The period of 1983-85 was an avante garde period which used rustic avante-garde materials and art craft materials. The period of 1986-87 can be described as minimalistic and neo-classical which incorporated materials which represents a metropolitan feel, retro decorative materials and sporty, futuristic mat-erials. Lastly, the period of 1988-89 produced ethnic and natural fashions which relied on traditional British materials, country elegant and innocent look fabrics, ethinic and ecology-minded materials, in addition to comfortable and sports casual materials. 3. Characteristrics and methods of expression for textiles in the 1980s, : In the 1980s, the development of textiles have can be divided into 4 distinct patterns: decorative materials, sporty materials. In generals textiles have increased in their decorative nature-especially decoration by texure. Textile have also incorporated the mixture of contrasting themes in order to create new fabrics.

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Ignition of a Vertically Positioned Fuel Plate by Thermal Radiation (열복사에 의한 수직연료면의 점화현상 해석)

  • 한조영;백승욱
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.19 no.9
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    • pp.2353-2364
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    • 1995
  • The ignition phenomena of a solid fuel plate of polymethyl-methacrylate(PMMA), which is vertically positioned and exposed to a thermal radiation source, is numerically studied here. A two-dimensional transient model includes such various aspects as thermal decomposition of PMMA, gas phase radiation absorption, gas phase chemical reaction and air entrainment by natural convection. Whereas the previous studies considers the problem approximately in a one-dimensional form by neglecting the natural convection, the present model takes account of the two-dimensional effect of radiation and air entrainment. The inert heating of the solid fuel is also taken into consideration. Radiative heat transfer is incorporated by th Discrete Ordinates Method(DOM) with the absorption coefficient evaluated using gas species concentration. The thermal history of the solid fuel plate shows a good agreement compared with experimental results. Despite of induced natural convective flow that induces heat loss from the fuel surface, the locally absorbed radiant energy, which is converted to the internal energy, is found to play an important role in the onset of gas phase ignition. The ignition is considered to occur when the rate of variation of gas phase reaction rate reaches its maximum value. Once the ignition takes place, the flame propagates downward.

An Investigation on the Historical Developments of the Algorithms for Multiplication of Natural Numbers (자연수 곱셈 계산법의 역사적 발달 과정에 대한 고찰)

  • Joung, Youn-Joon
    • School Mathematics
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    • v.13 no.2
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    • pp.267-286
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    • 2011
  • In this paper I investigated the historical developments of the algorithms for multiplication of natural numbers. Through this analysis I tried to describe more concretely what is to understand the common algorithm for multiplication of natural numbers. I found that decomposing dividends and divisors into small numbers and multiplying these numbers is the main strategy for carrying out multiplication of large numbers, and two decomposing and multiplying processes are very important in the algorithms for multiplication. Finally I proposed some implications based on these analysis.

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