• Title/Summary/Keyword: natural growth area

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Inhibitory Activity of Brine Mineral Water on Cancer Cell Growth, Metastasis and Angiogenesis (해양성 광천수의 암세포 성장, 전이 및 신생 혈관 생성 억제 효과)

  • Kim, Wan-Jae;Li, Hua;Yoon, Taek-Joon;Sim, Jae-Man;Choi, Seon-Kang;Lee, Kwang-Ho
    • The Korean Journal of Food And Nutrition
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    • v.22 no.4
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    • pp.542-547
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    • 2009
  • Brine mineral water(BMW) has recently gained attention as a new water resource due to its biological activities. In this study, BMW from the Geumjin area(Gangneung-city, Korea) was evaluated for its growth inhibition, anti-metastasis and anti-angiogenesis activity against cancer cells. The in vitro cytotoxicity was measured by CCK assay, and the anti-metastasis activity was estimated by lung metastasis in vivo. The in vitro incubation of mouse splenic cells with BMW that had been diluted more than 4-fold showed no effect on the cell growth when compared to a control group. Additionally, BMW inhibited the growth of the EL-4, L5178Y-R and colon26-M3.1 cancer cell lines in a dose-dependent manner. In vivo evaluation of the anti-metastasis activity of BMW in BALB/c mice inoculated with the colon26-M3.1 cell line revealed dose-dependent inhibition in response to treatment with samples that were diluted by up to 9 times. Finally, treatment with BMW effectively suppressed the growth of vascular endothelial growth factor(VEGF) added human umbilical vein endothelial cells. Overall, these results suggest that BMW has anti-cancer activity.

Growth, Feed Efficiency, Behaviour, Carcass Characteristics and Meat Quality of Goats Fed Fermented Bagasse Feed

  • Ramli, M.N.;Higashi, M.;Imura, Y.;Takayama, K.;Nakanishi, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.11
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    • pp.1594-1599
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    • 2005
  • The effects of long-term feeding of diets based on bermudagrass hay supplemented with lucerne hay cube (LH) or fermented bagasse feed (FBF) on the growth rate, feed efficiency, behaviour, gut development, carcass characteristics and meat quality of goats were investigated. Six spring-born 8-month-old male crossbred (Japanese Saanen${\times}$Tokara native goats) bucks weighing mean 21.6 kg were allotted to 2 treatment groups (3 animals each) and each animal had ad libitum access to feeds, i.e. bermudagrass hay (basal diet)+LH or FBF throughout the experiment. The FBF was produced by the solid-state fermentation of substrates containing dried sugarcane bagasse mixed with wheat bran in a ratio of 1:3 (w/w DM) with Aspergillus sojae. The live body weight, final weight and average daily gain were not different between treatments. Average basal diet intake of goats fed FBF diet was significantly higher than that fed LH diet (p<0.05), but average dry matter intake (DMI; g/day and g/$W^{0.75}$), feed conversion ratio, digestible crude protein (DCP) and total digestible nutrients (TDN) intake of experimental diets were not significantly different between treatments. Goats fed on LH and FBF diets had similar eating, rumination, resting and drinking behaviours, and blood constituents except for phosphorus content. Slaughter and carcass weights, net meat percentage [(total meat/carcass weight)${\times}$100], loin ratio [(loin/total meat)${\times}$100] and rib-eye area were not different between treatments. However, goats fed FBF diet had lower dressing percentage and higher bone/muscle ratio compared with goats fed LH diet (p<0.01). Empty gut and guts fill of goats fed FBF diet were significantly greater (p<0.05 and p<0.01, respectively) than those fed LH diet. The weights of rumen and abomasum were also significantly heavier in goats fed FBF diet (p<0.05), but the length and density of papillae of rumen in goats were not different between treatments. Although meat composition of loin was not different in both groups, the meat of goats fed FBF diet was superior to that of LH diet in flavor, aroma and overall quality of loin (p<0.01). In conclusion, the nature of the diet consumed voluntarily did not affect subsequent growth, nutrient intake and behaviour of goats but had an influence on carcass traits and sensory evaluation of meat partly, when either of LH or FBF was fed with bermudagrass hay.

Effects of Liquid Fertilizer Produced from Fermented Clippings for Creeping Bentgrass Growth (Creeping Bentgrass의 생육을 위한 예지물 발효 액상비료의 효과)

  • Kim, Sang-Jun;Kim, Do-Whan;Lee, Sang-Kook
    • Asian Journal of Turfgrass Science
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    • v.25 no.2
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    • pp.202-207
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    • 2011
  • Organic fertilizers are divided into natural organic and synthetic organics. The benefits of natural organic fertilizer were reported from the previous researches. However, the limited research results about clippings as a source of natural organic fertilizers were reported. The objective of the research to investigate effects of liquid fertilizer produced from fermented clippings for creeping bentgrass growth. Liquid fertilizer (LF) produced was used for the research to be compared with Urea and two natural organic fertilizers of different source (NO-1 and NO-2). Creeping bentgrass (Agrostis stolonifera L., L-93) was used for the study. Turfgrass quality was measured by visual evaluation every two weeks from June to October, 2011 using a scale of 1 to 9 (1=worst, 6=acceptable, and 9=best). Turfgrass disease damage was measured by percent of area damaged when a turfgrass disease occurred. LF produced lower damage than NO and urea when temperature was high. Although NO-2 produced the highest or equal to the highest turfgrass quality in June and October, LF had the highest or equal to the highest quality from July to September.

Effects of Native Korean Lespedeza(Lespedeza stipulacea Maxim.) on Soil Conservation (자생(自生) Korean Lespedeza(Lespedeza stipulacea Maxim.)가 토양보전(土壤保全)에 미치는 영향(影響))

  • Kim, Moo-Sung;Kim, Se-Young;Jeong, Woo-Jin
    • Korean Journal of Soil Science and Fertilizer
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    • v.30 no.1
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    • pp.72-83
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    • 1997
  • Forty six natural habitats of Korean lespedeza(Leapedeza stipulacea Maxim.) were investigated for the growth characteristics, mineral contents of plant and the physico-chemical properties of natural habitat's soil compared with the upland soil nearby the habitat. The results obtained were summarized as follows. Plant height and dry matter yield were higher in the samples taken in late than early August showing large variation within the sampling date and location. Korean lespedeza showed higher contents of Fe and Mn, but lower contents of K, Ca, Mg and Cu than Alfalfa. The contents of P and Zn were about the same. The natural habitat showed higher soil pH and Ca content but lower contents of $P_2O_5$, K, and organic matter than the vicinity of natural habitats and the average soil of Korea. The contents of Mg were about the same. The soil texture of natural habitats showed much higher portion of sand and extremely low portions of silt and clay than both area. Korean lespedeza is so well adapted to the soil with low fertilizer and organic matter that other crops and most weeds fail. It also appears to thrive on the sandy loams, loamy sands of the piedmont region such as waste land and on the similar soils with variously physico-chemical properties.

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The Development of Ecological Planting Model for the Make Up of Coastal Windbreak Forest on Suncheon Bay in Suncheon-si, Korea (순천만 해안방풍림 조성을 위한 생태학적 식재모델 개발)

  • Kim, Do-Gyun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.14 no.1
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    • pp.89-104
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    • 2011
  • This study was carried out to the development of ecological planting model to make up of coastal windbreak forest on the Suncheon-bay in Sucheon-si, Korea. Make up of coastal windbreak forest in this site was needed for appropriate bioresource, biodiversity and ecological structure, and for conservation of the eco-tour resource and protection of human life and property by the unforeseen disaster from the coast. Based on the plant-social principle, the planting model of windbreak forest was developed to facilitate growth of trees, considering planting locations. The ecological planting model for the coastal windbreak was composed of warm temperate evergreen and windbreak forest which is spreading around the inland area in Korea. The horizontal forest style was composed of forest edge community and inner forest community, and the vertical forest style was composed of upper, middle, low and ground planting class. The target of the present model was quasi-natural forest, and the species of tree were selected based on the adaptability to surroundings depending on a goal to create a forest and forest style. To achieve both functions of wind break forest and visual effect in short period of time, small trees and seedlings were planted with high-density of 40,000/ha in an expectation of easy natural maintenance in the future. The significance of the present study is a suggestion for a guideline to create ecological coastal windbreak forest in the Suncheon-bay in which the harmony of human life and the ecological conservation is of great importance. Also, the ecological coastal windbreak forest model should be developed further through the long term monitoring after construction of forest.

Natural Monument Cretaceous Stromatolite at the Daegu Catholic University, Gyeongsan: Occurrences, Natural Heritage Values, and Plan for Preservation and Utilization (천연기념물 경산 대구가톨릭대학교 백악기 스트로마톨라이트: 산상, 자연유산적 가치 및 보존·활용 방안)

  • KONG Dal-Yong;LEE Seong-Joo
    • Korean Journal of Heritage: History & Science
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    • v.56 no.3
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    • pp.214-232
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    • 2023
  • Stromatolite at the Daegu Catholic University, Gyeongsan was designated as a natural monument in December 2009 because it was very excellent in terms of rarity, accessibility, preservation and scale. From the time of designation, the necessity of confirming the lateral extension of the stromatolite beds with the excavation of the surrounding area, and preparing a preservation plan was raised. Accordingly, the Cultural Heritage Administration conducted an investigation of the scale, production pattern, and weathering state of stromatolites with an excavation from April to December 2022, and based on this, suggested natural heritage values and conservation and use plans. The excavation was carried out in a 1,186m2 area surrounding the exposed hemispherical stromatolite (approximately 30m2). Stromatolites are continuously distributed over the entire excavation area, and hemispherical stromatolites predominate in the eastern region, and the distribution and size of hemispherical domes tend to decrease toward the west. These characteristics are interpreted as a result of long-term growth in large-scale lakes, where stratiform or small columnar domes continued to grow and connect with each other, finally forming large domes. Consequently, large and small domes were distributed on the bedding plane in clusters like coral reefs. The growth of plants and lichens, as well as small-scale faults and joints developed on the stromatolite bedding surface, is the main cause of accelerated weathering. However, preservation treatment with chemicals as with dinosaur footprints or dinosaur egg fossil sites is not suitable due to the characteristics of stromatolites, and preservation with the installation of closed protection facilities should be considered. This excavation confirmed that the distribution, size and value of stromatolites are much larger and higher than at the time of designation as a natural monument. Therefore, additional excavation of areas by experts that could not be excavated due to the discovery of buried cultural properties (stone chamber tombs) and reexamination of the expansion designation of natural monuments are required.

Effect of Temperature Variables on Growth and Inorganic Nutrient Contents of Codonopsis lanceolata

  • Kwon, Soo-Jeong;Seo, Dong-Yeon;Cho, Gab-Yeon;Lee, Moon-Soon;Boo, Hee-Ock;Woo, Sun-Hee;Kim, Hag-Hyun
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.61 no.2
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    • pp.131-137
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    • 2016
  • This study was conducted to investigate the effects of temperature and shade, which are basic environmental conditions, on growth, yield, inorganic components, and general components of Codonopsis lanceolata, in order to obtain basic data for improving yield capacity. In natural light, in the 15, 20, and $25^{\circ}C$ groups, the plant heights ranged between 218.9 cm and 223.9 cm, and there was no significant difference between groups. However, the leaf size was larger in shade, and the leaf area was significantly larger in the 15 and $30^{\circ}C$ groups. In natural light, root length and diameter were shorter and thinner when the temperature was higher, and growth was highly suppressed at $30^{\circ}C$. With regards to macroelements, the contents of Na, Mg, and P increased as temperature increased, regardless of the plant part; however, no constant tendency was observed in K and Ca according to temperature. The contents of Mg and Ca (from highest to lowest) were in the order leaf>stem>root, whereas the contents of Na, P, and K were in the order stem>leaf>root. Contents of general components varied according to temperature, and were highest at $30^{\circ}C$. While the plant height was increased under the constant $25^{\circ}C$+DIF (Difference between day and night temperature) condition, growth was suppressed in the -DIF group, in which the night temperature was higher than the day temperature, which suggests that a change in night temperature is one of the factors that affects the growth of C. lanceolata. As in the growth of the above-ground parts, fresh weight of the root was high in the constant $25^{\circ}C$ group and +DIF group. Notably, it was more than 2.5 times the fresh weights in the constant $15^{\circ}C$ group, constant $20^{\circ}C$ group, and -15 DIF group.

The Transition of Fertility and the Depopulation by the Stage Migration: A case study of Jeollabuk-do (단계적 인구이동에 따른 출산력 변화와 과소화: 전라북도를 사례로)

  • Lee, Chungsup;Kim, Sung Hwan
    • Journal of the Korean Geographical Society
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    • v.49 no.5
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    • pp.728-746
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    • 2014
  • The purpose of this study is to analyze the influence of the selective migration of young age group and the stage migration which has proceeded through generations, on the transition of fertility and the population growth in the rural and urban in the case of Jeollabuk-do. For this, we use O-D matrix of 20-34 age group, the distribution of that group and women of child bearing age, and vital statistics in 1970-2010. The major findings of this study are as follows. First, the outflows from their birth place are common and dominant features of 20-34 age group in each time. Second, there is the stage migration which preceding generation moved from the rural areas to the cities in Jeollabuk-do and following generation has moved from the cities to Seoul metropolitan area. Third the selective outflow migration of young age group has leaded to reduction of the childbearing population, declining birthrate, aging and natural population decline. Due to the stage migration, these depopulation processes occurred in rural area in the past, and currently it expands to the cities with about 15 years time gap. In fact, there have been the natural population decrease which annual number of deaths exceed that of births from the late 1980s in the most rural areas and in the early 2000s, such a phenomenon has been confirmed also in urban areas. Therefore, this study concludes that the stage migration through generations is one of the crucial factor to the population growth in local cities and also brings out the step-wise population decrease in settlement hierarchies.

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Microbial Effects on Geochemical Behavior of Arsenic under Aresnic under Aerobic Condition and Their Applicability to Environmental Remediation (호기성환경에서 비소의 지구화학적 거동에 미치는 미생물의 영향 및 오염 복구에의 적용 가능성)

  • Lee, Sang-U;Kim, Gyeong-Ung;Lee, Jong-Un
    • Economic and Environmental Geology
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    • v.34 no.4
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    • pp.345-354
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    • 2001
  • The effects on arsenic geochemistry of indigenous microorganisms isolated from an area contaminated with high concentration of arsenic were investigated. Arsenite exerted higher inhibitory effects on the microbes' growth than arsenate. During incubation of the microbes in an arsenate-spiked medium over 24 hours, decrease in microbial growth was observed as arsenate content increased. Arsenate of 150 mM or over apparently inhibited cell growth. However, further incubation for up to 4 days in the high arsenate concentration medium resulted in cell growth, implying that the microorganisms adjusted their biochemical functions to detoxify arsenic and maintain growth. Two types of microbes were observed during 20 hours to reduce arsenate to arsenite in solution through a detoxification mechanism. As well, decrease in the total arsenic content occurred over a 4-day incubation with the same microbes in an arsenate-spiked medium. Therefore it is suggested that microorganisms can influence arsenic speciation in natural settings and this may be applied to efficient bioremediation of arsenic-contaminated sites.

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Cucumber Growth and Nitrogen Uptake as Affected by Solution Temperature and NO3-:NH4+ Ratios during the Seedling

  • Yan, Qiu-Yan;Duan, Zeng-Qiang;Li, Jun-Hui;Li, Xun;Dong, Jin-Long
    • Horticultural Science & Technology
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    • v.31 no.4
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    • pp.393-399
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    • 2013
  • The effect of solution temperature and nitrogen form on cucumber (Cucumis sativus L.) growth, photosynthesis and nitrogen metabolism was investigated in hydroponic culture. Cucumber plants were grown for 35 days in a greenhouse at three constant solution temperatures ($15^{\circ}C$, $20^{\circ}C$, and $25^{\circ}C$) within a natural aerial temperature ($15-30^{\circ}C$). Four nitrate:ammonium ($NO{_3}^-:NH{_4}^+$) ratios (10:0, 8:2, 5:5, and 2:8 $mmol{\cdot}L^{-1}$) at constant nitrogen (N) concentration of $10mmol{\cdot}L^{-1}$ were applied within each solution temperature treatment. Results showed an increasing solution temperature enhanced plant growth (height, dry weight, and leaf area) in most N treatments. Dry weight accumulation was greatest at the 10:0 $NO{_3}^-:NH{_4}^+$ ratio in the $15^{\circ}C$ solution, the 5:5 ratio in the $20^{\circ}C$ solution and the 8:2 ratio in the $25^{\circ}C$ solution. Photosynthetic rate (Pn) response to solution temperature and $NO{_3}^-:NH{_4}^+$ ratio was similar to that of plant growth. Probably, the photosynthate shortage played a role in the reduced biomass formation. Increasing solution temperature enhanced the nitrate reductase (NR) activity, and further reduced shoots nitrate content. Our results indicate that the optimal ratio of nitrate to ammonium that promotes growth in hydroponic cucumber varies with solution temperature.