• Journal of Korean Home Economics Education Association
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• v.27 no.2
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• pp.35-51
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• 2015

The purpose of the present study is to investigate the various reasons that might lead single women to choose not to marry. Semi-structured in-depth interviews were arranged with 18 single women who met the criteria for the present research purpose. We considered only those responses of the interviewees that are directly related to their reasons why they choose not to marry, where the collected data were analyzed in three steps by methods of thematic analysis. As a result of the analysis, the reasons for which they chose not to marry could be grouped into three main clusters of themes which may be labeled as (1) themes centered on 'Myself', (2) themes centered on 'Family' and (3) themes centered on 'Surrounding Environments and Friends'. Among the first category of themes of 'Myself', we have found five sub-themes such as "Lack of emotional communication", "Not-found spouse meeting my criteria", "My personality", "Self-narcissism or self-centeredness", "False beliefs in marriage". As for the second category of themes 'Family', three sub-themes have been found including "Family of origin conflict", "Closeness to family of origin", "Comfortable daily lives". And for the final category of themes 'Surrounding Environments and Friends', there were found three sub-themes which include "Negative effects of married friends", "Emotional support system", "Changing social atmosphere". In all there are eleven sub-themes to consider. On the basis of these results, we presented some conclusions on the reasons why single women in their thirties or forties choose not to marry. We also presented some implications of these results on population education and future research.

• Magazine of the Korean Society of Agricultural Engineers
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• v.11 no.2
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• pp.1644-1650
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• 1969

In the design of general hydrological structures, it is well know that the design flood is of importance in the design of those structures. As the design flood is estimated using the design storm, the design storm is defined by the rainfall intensity itself. Though I had studied and reported many times the reports about the rainfall-intensity in my country, poorly I did not study the long-period variation of the intensity through each section in my country before. But now, in the basin area of the Han river and the Keum river, the self-recorded rainfall charts of the single storms, which are mostly above rainfall amount of 30mm and data of about 4500 with the 150 stationyear, were analyzed, And then, the intensity formula of the hourly unit is estimated using the period from 10 minutes to 5 days. The method to analyze and estimate them, and the final results will be summarized as mentioned below: (i) At first I intended to select out the homogeneous watersheds of three, one in the Han river and two in the Keum river. But I would select the northern and the sourthern river basins, and westward from Koan station, in the basins of the Han river. Also I would select the upstream area, and the downstream area including the watershed of Chungioo, Kongjoo, Chupungryung, and the Mt. Sock, in the basins of the Keum river. Finally, I could find that there couldn't in the Keum river basin. So, I decided out and analyze only river basins of the Han river with limitation mentioned above. (ii) The statistical method to select out the homogenous watersheds is the test of homogeneous variance, and it is estimated from the following equation: $$X_{k1}^2=[{\Sigma}(n_i-1)log\bar{S^2}-\Sigma(n_i-1)log\bar{S^2}]{\times}loge$$ (iii) Actually, each homogeneous watershed has individually its own intensity formula, But I would express them as the actual amount, because the equation of intensity variance is experiential and theoretical equation of the variance. Therefore the caluating equation is actually more convenient in the actual uses. (iv) This report is one of the series for me to give the basis to the actual designs. The cost for this study is provided by the Ministry of Construction. And the designs of the hydrological structures in the watersheds with limitation mentioned above may be concerned with and based upon this report.

• Journal of Hospice and Palliative Care
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• v.18 no.3
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• pp.188-195
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• 2015

Purpose: We examined the effects of a well-dying program on nursing students in terms of death preparation, death recognition and perception of well-dying perception. Methods: The design of this study was quasi-experimental and non-synchronized with a non-equivalent control group. The study was conducted with nursing students: 32 in the experimental group and 36 in the control group. The well-dying program was consisted of five sessions: introduction, thinking about meaning of death, organizing things to do before dying, looking back on my life, and leaving a trail of my life. Descriptive analysis, t-test, ${\chi}^2$ test and ANCOVA were used with SPSS 18.0 program to analyze the data. Results: After attending the program, a difference was observed in death preparation of the experimental group (t=2.61, P=0.014). The death recognition (F=154.15, P<0.001) score of the experimental group was significantly higher than the control group. There was no significant difference between the groups in perception of well-dying (F=0.11, P=0.747). Conclusions: The well-dying program helped nursing students build positive death recognition. Therefore, this study is expected to contribute to development of a death education program for nursing students.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.92-92
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• 2019

Excessive or chronic inflammation contributes to the pathogenesis of many inflammatory diseases such as sepsis, rheumatoid arthritis, and ulcerative colitis. Hibiscus syriacus L. has been used as a medicinal plant in many Asian countries, even though its anti-inflammatory activity has been unclear. Therefore, we investigated the anti-inflammatory effect of anthocyanin fractions from the H. syriacus L. varieties Pulsae (PS) on the lipopolysaccharide (LPS)-induced expression of proinflammatory mediators and cytokines in RAW264.7 macrophages. PS suppressed LPS-induced nitric oxide (NO) and prostaglandin $E_2$ ($PGE_2$) secretion concomitant with downregulation of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) expression. Furthermore, PS inhibited the production of proinflammatory cytokines such as tumor necrosis factor-alpha ($TNF-{\alpha}$), interleukin-6 (IL-6), and IL-12 in LPS-stimulated RAW264.7 macrophages. Further study showed that PS significantly decreased LPS-induced nuclear translocation of the nuclear $factor-{\kappa}B$ ($NF-{\kappa}B$) subunits, p65 and p50. Molecular docking data showed that many anthocyanins from PS fit into the hydrophobic pocket of MD2 and bound to Toll-like receptor 4 (TLR4), indicating that PS inhibits the TLR4-MD2-mediated inflammatory signaling pathway. Especially, apigenin-7-O-glucoside most powerfully bound to MD2 and TLR4 through LYS122, LYS122, and SER127 at a distance of $2.205{\AA}$, $3.098{\AA}$, and $2.844{\AA}$ and SER441 at a distance of $2.873{\AA}$ (docking score: -8.4) through hydrogen bonding, respectively. Additionally, PS inhibited LPS-induced TLR4 dimerization/expression on the cell surface, which consequently decreased MyD88 recruitment and IRAK4 phosphorylation. PS completely blocked LPS-mediated mortality in zebrafish larvae by diminishing the recruitment of neutrophil and macrophages accompanied by low levels of proinflammatory cytokines. Taken together, our results indicate that PS attenuates LPS-mediated inflammation in both in vitro and in vivo by blocking the TLR4/MD2-MyD88/IRAK4-$NF-{\kappa}B$ axis. Therefore, PS might be used as a novel modulatory candidate for effective treatment of LPS-mediated inflammatory diseases.

• Clinical and Experimental Reproductive Medicine
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• v.50 no.1
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• pp.44-52
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• 2023

Objective: The DNA integrity of spermatozoa that attach to fallopian tube (FT) cells is higher than spermatozoa that do not attach. FT epithelial cells can distinguish normal and abnormal sperm chromatin. This study investigated the effects of sperm with a high-DNA fragmentation index (DFI) from men with unexplained repeated implantation failure (RIF) on the Toll-like receptor (TLR) signaling pathway in human FT cells in vitro. Methods: Ten men with a RIF history and high-DFI and 10 healthy donors with low-DFI comprised the high-DFI (>30%) and control (<30%) groups, respectively. After fresh semen preparation, sperm were co-cultured with a human FT epithelial cell line (OE-E6/E7) for 24 hours. RNA was extracted from the cell line and the human innate and adaptive immune responses were tested using an RT2 profiler polymerase chain reaction (PCR) array. Results: The PCR array data showed significantly higher TLR-1, TLR-2, TLR-3, TLR-6, interleukin 1α (IL-1α), IL-1β, IL-6, IL-12, interferon α (IFN-α), IFN-β, tumor necrosis factor α (TNF-α), CXCL8, GM-CSF, G-CSF, CD14, ELK1, IRAK1, IRAK2, IRAK4, IRF1, IRF3, LY96, MAP2K3, MAP2K4, MAP3K7, MAP4K4, MAPK8, MAPK8IP3, MYD88, NFKB1, NFKB2, REL, TIRAP, and TRAF6 expression in the high-DFI group than in the control group. These factors are all involved in the TLR-MyD88 signaling pathway. Conclusion: The MyD88-dependent pathway through TLR-1, TLR-2, and TLR-6 activation may be one of the main inflammatory pathways activated by high-DFI sperm from men with RIF. Following activation of this pathway, epithelial cells produce inflammatory cytokines, resulting in neutrophil infiltration, activation, phagocytosis, neutrophil extracellular trap formation, and apoptosis.

• Journal of Applied Reliability
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• v.15 no.2
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• pp.90-100
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• 2015

Reliability growth rate (or reliability growth curve slope) have the two cases of trend as a constant or changing one during the reliability growth testing. The changing case is very common situation. The reasons of reliability growth rate changing are that the failures to follow the NHPP (None-Homogeneous Poisson Process), and the solutions implemented during test to break out other problems or not to take out all of the root cause permanently. If the changing were big, the "Goodness of Fit (GOF)" of reliability growth curve to test data would be very low and then reduce the accuracy of assessing result with test data. In this research, we are using Duane model and AMSAA model for assessing test data and projecting the reliability level of complex and repairable system as like construction equipment and vehicle. In case of no changing in reliability growth rate, it is reasonable for reliability engineer to implement the original Duane model (1964) and Crow-AMSAA model (1975) for the assessment and projection activity. However, in case of reliability growth rate changing, it is necessary to find the method to increase the "GOF" of reliability growth curves to test data. To increase GOF of reliability growth curves, it is necessary to find the proper parameter calculation method of interesting reliability growth models that are applicable to the situation of reliability growth rate changing. Since the Duane and AMSAA models have a characteristic to get more strong influence from the initial test (or failure) data than the latest one, the both models have a limitation to contain the latest test data information that is more important and better to assess test data in view of accuracy, especially when the reliability growth rate changing. The main objective of this research is to find the parameter calculation method to reflect the latest test data in the case of reliability growth rate changing. According to my experience in vehicle and construction equipment developments over 18 years, over the 90% in the total development cases are with such changing during the developing test. The objective of this research was to develop the newly assessing method and the process for GOF level increasing in case of reliability growth rate changing that would contribute to achieve more accurate assessing and projecting result. We also developed the new evaluation method for GOF that are applicable to the both models as Duane and AMSAA, so it is possible to compare it between models and check the effectiveness of new parameter calculation methods in any interesting situation. These research results can reduce the decision error for development process and business control with the accurately assessing and projecting result.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.45 no.1
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• pp.30-35
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• 2017

In this study, we measured the natural frequencies of aluminum honeycomb sandwich beams using digital image correlation technique. The vibration images were captured using two high speed digital cameras and the images were converted to displacements by the digital image correlation technique. Displacement data in time domain were tranformed to frequency domain data by fast Fourier transform software. To reduce noise invoked by random exitation, a spectrum averaging technique and Savitsky-Golay digital filter were adopted. A conventional vibration measurement using an accelerometer and a finite element analysis were performed to compare the results by high speed digital camera measurement method. In conclusion, new method using high speed digital cameras and digital image correlation technique can measure the vibration of beam structures and can be applied to bio-structures where sensors cannot be attached.

• Research in Community and Public Health Nursing
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• v.13 no.2
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• pp.216-229
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• 2002

Objectives: This study was conducted to investigate the effects of a self growth program through MBTI on interpersonal relationships, and the career identity of nursing college students. Methods: A randomized controlled pre-post test experimental design was used for this study. The 24 nursing students were randomly assigned into two groups: 12 for the experimental group, and 12 for the control group. The subjects were junior nursing students, who were randomly selected from an undergraduate nursing program at K university located in Daegu, Korea. The data was collected from March 18 to April 1, 2002. The MBTI self growth program used in this study was based on the one developed by Shim and Kim (1997). The 12 experimental group students received the group self growth program through MBTI for 15 hours, while the 12 control group students received no treatment, except a series of tests. The Korean version MBTI test used in this study was developed and verified for reliability and validity by Kim and Sim (1990). Change in inter-personal relationships was measured using the Relationship Change Scale developed by Schlein and Guerney (1971), and modified by Lee and Mun (1982). Career identity was measured using the My Vocational Situation developed by Holland. Daiger and Power (1980), and revised by Kim (1997). The data were analyzed with the SPSS Win 10.0 program, through which the 2 test, t-test, and Repeated measures ANOVA were examined. Results: 1) The first hypothesis, 'the experimental group that received the self growth program through MBTI will obtain a higher interpersonal relationship score than the control group', was supported (F=5.295. p=.031. Interaction: p=.000). 2) The second hypothesis, 'the experimental group that received the self growth program through MBTI will obtain a higher career identity score than the control group', was supported (F=28.575, p=.000, Interaction: p=.000). Conclusion: The results showed that the ready planned self growth program through MBTI had positive effects on improving the interpersonal relationships, and the career identity of nursing college students.

• Korean Journal of Human Ecology
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• v.19 no.6
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• pp.1083-1094
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• 2010

The purpose of this study is to provide a fundamental research data that is necessary in an education of dietary life so that the students have sound dietary life through a right food purchase after investigating perception of children's dietary habit and activity, food labelling, and nutrition labelling for 400 students of the 5 and 6th grades. The result of the study are as followings. In terms of perception questions over food labelling, on the whole, "know it little bit" was the highest. Girls and country was higher than boys and city. A list of item that is important in contents of food labelling were period of circulation, data of manufacturing, price, used ingredient, origin of product, nutrition contain labelling, manufacturer, quantity in contents(quantity, the number). A meaningful difference was shown in gender(p<.05) and area(p<.01). In 30 perception questions over nutrition labelling, "know it little bit" was the most, and girls and country were higher than boys and city. In ascertaining nutrition labelling at the time of purchasing the food, "look often" was the most. Girls and city were higher than boys and Gun in average but no difference was statistically shown in knowledge mark in utilization and perception of nutrition labelling. The response rate in girls(p<.01) and country(p<.05) was higher in a question of "if nutrition labelling is displayed, nutriment that is harmful for our body will be eaten less" and girls' response rate was higher in the question of "being educated for my health". Therefore, practice centered nutrition education is necessary to purchase the food after ascertaining food nutrition labelling out of an attitude in habitually purchasing the processed food. The students develop comprehensible food nutrition labelling the direction to emphasizing nutrition educational labelling and recognizing that the healthy nutriment is contained without conventional and food safety centered labelling should be changed.

• The Journal of the Korea Contents Association
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• v.16 no.9
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• pp.791-805
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• 2016

The purpose of this study was to understand the essential meanings in experiences of medication misuse and abuse behavior in elderly people with chronic disease in community. The participants were 10 patients with chronic disease over 65 ages who were selected by convenience sampling. Data were collected through individual in-depth interviews from February to May 2014, and were analyzed using Colaizzi (1978)'s phenomenological analysis method. As a results, the essential meanings and structure of medication misuse and abuse behavior experience in elderly people with chronic disease were derived into five clusters of themes as follows: 'Burden on the medications', 'Anxiety about the side effect of the medications or the disease exacerbation', 'There is no alternative other than the medications', 'Expectations of the medications effect for my criteria', 'Lack of understanding on the correct medication use'. The results of this study contributed to promoting a deeper understanding of medication misuse and abuse behaviors in elderly people with chronic disease, and provided for the basic data of strategic development for the prevention of medication misuse and abuse behaviors from the perspective of elderly people with chronic disease in community.