• Kyungpook Mathematical Journal
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• 제49권2호
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• pp.265-281
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• 2009

In the present paper, we introduce and investigate a new subclass of multivalent functions associated with the Cho-Kwon-Srivastava operator $\tau^{\lambda}_p(a,c)$. Such results as inclusion relationships, convolution properties and criteria for starlikeness are proved. Relevant connections of the results presented here with those obtained in earlier works are also pointed out.

• 대한수학회보
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• 제25권2호
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• pp.221-232
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• 1988

• 한국동물위생학회지
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• 제40권2호
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• pp.133-137
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• 2017

Three swine farms which were suffering from slight economic loss due to suckling piglets' diarrhea, were selected to apply commercialized multivalent vaccine for sow use; $SUISENG^{(R)}$ (Hipra, Spain). Farms were pre-diagnosed with clinical symptoms and molecular detection of C. perfringens Type A and C and E. coli pili by PCR. Sows were vaccinated twice 2 ml of the vaccine at 6 and 3 weeks ante partum intramuscularly according to the manufacturer's instruction. All vaccinated sows did not show any adverse reaction or clinical signs; hypersensitivity, fever, granuloma or abscess on the injection site, appetite loss, and so on. Also, no reproductive disorder was appeared in vaccinated sows compared with non-vaccinated control sows. The results suggested that piglets born from vaccinated sows show significantly better performance in regard of the diarrhea index and mean daily weight gain compared with piglets from non-vaccinated sows. Therefore, the commercial vaccine for the prevention of neonatal diarrhea is found to be effective in reducing diarrhea in the first suckling period of piglets after birth.

• Bulletin of the Korean Chemical Society
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• 제30권5호
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• pp.1101-1106
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• 2009

Multivalent and multi-specific antibodies can provide valuable tools for bio-medical research, diagnosis and therapy. In antigen-antibody interactions, the avidity of antibodies depends on the affinity and the number of binding sites.$^1$ As artificial multivalent antibody agents, single chain Fv-streptavidin fusion tetramer proteins $(scFv-SA)_4$ have been previously tested.$^{1,\;2}$ Although, the Fab domain is known to be more stable than scFv in animal models,$^{3,\;4}$ it has never been used to make a multivalent agent with a streptavidin fusion. In this study, we prepared tetra-valent $(Fab-cSA)_4$ by fusing Fab with core streptavidin (cSA). This molecule was made using inclusion body production, refolding and chromatography purification. Affinities of the Fab-cSA tetramer and a scFv-cSA tetramer to a cell surface antigen were compared by ELISA using biotin-HRP. The Fab-cSA tetramer showed higher binding avidity than the scFv-cSA tetramer. The higher binding avidity of the Fab-cSA tetramer demonstrates its potential as a therapeutic agent for target-specific antibody therapy.

• 대한수학회보
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• 제56권4호
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• pp.911-927
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• 2019

Let $\mathscr{B}^{{\eta},{\mu}}_{p,n}\;({\alpha});\;({\eta},{\mu}{\in}{\mathbb{R}},\;n,\;p{\in}{\mathbb{N}})$ denote all functions f class in the unit disk ${\mathbb{U}}$ as $f(z)=z^p+\sum_{k=n+p}^{\infty}a_kz^k$ which satisfy: $$\|\[{\frac{f^{\prime}(z)}{pz^{p-1}}}\]^{\eta}\;\[\frac{z^p}{f(z)}\]^{\mu}-1\| <1-{\frac{\alpha}{p}};\;(z{\in}{\mathbb{U}},\;0{\leq}{\alpha}<p)$$. And $\mathscr{M}^{{\eta},{\mu}}_{p,n}\;({\alpha})$ indicates all meromorphic functions h in the punctured unit disk $\mathbb{U}^*$ as $h(z)=z^{-p}+\sum_{k=n-p}^{\infty}b_kz^k$ which satisfy: $$\|\[{\frac{h^{\prime}(z)}{-pz^{-p-1}}}\]^{\eta}\;\[\frac{1}{z^ph(z)}\]^{\mu}-1\|<1-{\frac{\alpha}{p}};\;(z{\in}{\mathbb{U}},\;0{\leq}{\alpha}<p)$$. In this paper several sufficient conditions for some classes of functions are investigated. The authors apply Jack's Lemma, to obtain this conditions. Furthermore, sufficient conditions for strongly starlike and convex p-valent functions of order ${\gamma}$ and type ${\beta}$, are also considered.

• 대한수학회보
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• 제22권2호
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• pp.101-116
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• 1985

• 대한수학회논문집
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• 제8권1호
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• pp.23-32
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• 1993

• Kyungpook Mathematical Journal
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• 제32권2호
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• pp.183-195
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• 1992

• 대한수학회지
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• 제25권1호
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• pp.53-66
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• 1988

• Kyungpook Mathematical Journal
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• 제32권1호
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• pp.87-96
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• 1992