• Applied Chemistry for Engineering
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• v.19 no.3
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• pp.277-286
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• 2008

This paper deals with the theoretical derivation of the modified Haldane model of the substrate inhibition in the microbial growth processes. Based on the biological concepts of substrate-receptor complex working mechanisms, a new microbial kinetics of N-fold multiplex substrate inhibition and its generalization has been considered theoretically, which is natural expansion of the simple substrate inhibition mechanism in the enzyme reaction. As a result, the modified Haldane model of the substrate inhibition turns out to be a well-designed four-parameter kinetic model with a biological constant of the total substrate inhibition concentration.

• Journal of Microbiology and Biotechnology
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• v.18 no.6
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• pp.1130-1135
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• 2008

The effect of pH on anaerobic hydrogen production was investigated under various pH conditions ranging from pH 3 to 10. When the modified Gompertz equation was applied to the statistical analysis of the experimental data, the hydrogen production potential and specific hydrogen production rate at pH 5 were 1,182 ml and 112.5 ml/g biomass-h, respectively. In this experiment, the maximum theoretical hydrogen conversion ratio was 22.56%. The Haldane equation model was used to find the optimum pH for hydrogen production and the maximum specific hydrogen production rate. The optimum pH predicted by this model is 5.5 and the maximum specific hydrogen production rate is 119.6 ml/g VSS-h. These data fit well with the experimented data($r^2=0.98$).

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.74.3-74
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• 2001

This paper proposes a nonlinear adaptive controller based on back-stepping method for tracking reference substrate concentration by manipulating dilution rate in a continuous baker´s yeast cultivating process in stirred tank bioreactor. Control law is obtained from Lyapunov control function to ensure asymptotical stability of the system. The Haldane model for the specific growth rate depending on only substrate concentration is used in this paper. Due to the uncertainty of specific growth rate, it has been modified as a function including the unknown parameter with known bounded values. The substrate concentration in the bioreactor and feed line are measured. The deviation from the reference is observed when the external disturbance such as the change of the feed is introduced to the system ...

• Transactions on Control, Automation and Systems Engineering
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• v.4 no.4
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• pp.277-282
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• 2002

This paper proposes a nonlinear adaptive controller based on back-stepping method for tracking reference substrate concentration by manipulating dilution rate in a continuous baker's yeast cultivating process in stirred tank bioreactor. Control law is obtained from Lyapunov control function to ensure asymptotical stability of the system. The Haldane model for the specific growth rate depending on only substrate concentration is used in this paper. Due to the uncertainty of specific growth rate, it has been modified as a function including the unknown parameter with known bounded values. The substrate concentration in the bioreactor and feed line are measured. The deviation from the reference is observed when the external disturbance such as the change of the feed is introduced to the system. The effectiveness of the proposed controller is shown through simulation results in continuous system.

• Environmental Engineering Research
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• v.22 no.4
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• pp.417-425
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• 2017

Indonesia is known as the largest oil palm producer in the world. However, along with the production, it generates wastes and pollution that caused the environmental problem in surrounding areas. Previous researchers reported that the high palm oil mill effluent (POME) concentration inhibited microalgae growth. However, the inhibition factor was not clearly explained by using kinetic model. This study presents kinetic models of Botryococcus braunii (B. braunii) cultivated on POME wastewater under different turbidity condition. Results showed that the growth model of Zwietering was closely suitable with experimental results. It was found that B. braunii was able to consume organic carbon from the POME wastewater on the logarithmic model. A modified kinetic model of Monod Haldane described the influence of turbidity and chemical oxygen demand on the cultivation. Turbidity of POME medium inhibited the growth rate at KI 3.578 and KII 179.472 NTU, respectively. The Lipid (39.9%), and carbohydrate (41.03%) were found in the biomass that could be utilized as biofuel source.

• Journal of Korean Society of Environmental Engineers
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• v.29 no.1
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• pp.54-61
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• 2007

The influences of pH were investigated for anaerobic hydrogen gas production under the constant pH condition ranged from pH 3 to 10. Carbon dioxide and hydrogen gas were main components of the gas but methane was not detected in the produced gas when sucrose was added in enrichment medium. When the modified Gompartz equation was applied for the statistical analysis of experimental data, a hydrogen production potential and maximum gas production rate at pH 5 were 1,182 mL and 112.46 mL/g dry wt biomass/hr. The hydrogen conversion ratio was 22.56%. The butyrate/acetate ratios at pH 5 and pH 6 are 1.63 and 0.38. Higher butyrate/acetate ratio produced more hydrogen gas generation. The Haldane equation model was used to find the optimum pH and fitted well with the experimental data$(r^2=0.98)$. The optimum pH and specific hydrogen production were 5.5 and 119.61 mL/g VSS/h.