• Biomedical Science Letters
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• v.23 no.1
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• pp.8-16
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• 2017

p-Coumaric acid is an organic compound that is a hydroxyl derivative of cinnamic acid. Due to its multiple biological activities p-coumaric acid has been widely studied in biochemical and cellular systems and is also considered as a useful therapeutic candidate for various neuronal diseases. However, the efficacy of p-coumaric acid on zebrafish developmental regulation has not been fully explored. In this study, therefore, we first investigated the action mechanism of the p-coumaric acid on the zebrafish development in a whole-organism model. p-Coumaric acid treated group significantly inhibited the pigmentation of the developing zebrafish embryos compared with control embryos without any severe side effects. In addition, p-coumaric acid down-regulated more effectively in a lower concentration than the well-known zebrafish's melanogenic inhibitor, phenylthiourea. We also compared the molecular docking property of p-coumaric acid with phenylthiourea on the tyrosinase's kojic acid binding site, which is the key enzyme of zebrafish embryo pigmentation. Interestingly, p-coumaric acid interacted with higher numbers of the amino acid residues and exhibited a tight binding affinity to the enzyme than phenylthiourea. Taken all together, these results strongly suggest that p-coumaric acid inhibits the activity of tyrosinase, consequently down-regulating zebrafish embryo pigmentation, and might play an important role in the reduction of dermal pigmentation. Thus, p-coumaric acid can be an effective and non-toxic ingredient for anti-melanogenesis functional materials.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 2017.04a
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• pp.17-17
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• 2017

In electric agricultural machine the gearhead is needed to convert the high speed low torque rotation motion generated by DC motor to lower speed high torque motion used by the vehicle. The gearhead consist of several spur gears works as reduction gears. Spur gear have straight tooth and are parallel to the axis of the wheel. Spur gears are the most easily visualized gears that transmit motion between two parallel shafts and easy to produce. The modeling and simulation of spur gears in DC motor gearhead is important to predict the actual motion behavior. A pair of spur gear tooth in action is generally subjected to two types of cyclic stress: contact stress and bending stress including bending fatigue. The stress may not attain their maximum values at the same point of contact fatigue. These types of failure can be minimized by analysis of the problem during the design stage and creating proper tooth surface profile with proper manufacturing methods. To improve its life expectation in this study modal and stress analysis of gearhead is simulated using ansys work bench software based on finite element method (FEM). The modal analysis was done to understand gearhead deformation behaviour when vibration occurs. FEM static stress analysis is also simulated on gearhead to simulate the gear teeth bending stress and contact stress behavior. This methodology serves as an approach for gearhead design evaluation, and the study of gear stress behavior in DC motor gearhead which is needed in the small workshop scale industries.

• Journal of Educational Research in Mathematics
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• v.18 no.4
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• pp.483-497
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• 2008

This study investigated what kind of informal knowledge is emergent and what role informal knowledge play in process of solving 2-digit by 2-digit multiplication task. The data come from 4 times interviews with a 3th grade student who had not yet received regular school education regarding 2-digit by 2-digit multiplication. And the data involves the student's activity paper, the characteristics of action and the clue of thinking process. Findings from these interviews clarify the child's informal knowledge to modeling strategy, doubling strategy, distributive property, associative property. The child formed informal knowledge to justify and modify her conjecture of the algorithm.

• Archives of design research
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• v.16 no.4
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• pp.355-364
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• 2003

The TUI system Modeling Language(TML) developed in this research can be used for designing TUI system with concerning about TUI's characters. For design to be concerned about physical property of tangibles and control device and digital media, TML can be a framework to give a definition of each property and be used for designing action and reaction process separately. And it would be the guideline to represent interaction's dynamic property through showing parallel information flows among objects. Finally, for verification TML's suitability, TUI system to which TML was applied was developed.

• Journal of KIISE
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• v.41 no.12
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• pp.1035-1049
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• 2014

This paper presents a new method to detect attack patterns in security-critical systems, based on a new notion of Behavior Ontology. Generally security-critical systems are large and complex, and they are subject to be attacked in every possible way. Therefore it is very complicated to detect various attacks through a semantic structure designed to detect such attacks. This paper handles the complication with Behavior Ontology, where patterns of attacks in the systems are defined as a sequences of actions on the class ontology of the systems. We define the patterns of attacks as sequences of actions, and the attack patterns can then be abstracted in a hierarchical order, forming a lattice, based on the inclusion relations. Once the behavior ontology for the attack patterns is defined, the attacks in the target systems can be detected both semantically and hierarchically in the ontology structure. When compared to other attack models, the behavior ontology analysis proposed in this paper is found to be very effective and efficient in terms of time and space.

• KIPS Transactions on Software and Data Engineering
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• v.2 no.11
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• pp.815-822
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• 2013

Nowadays, the various kind of software packages that support content creation consumed in touch-type terminals as an application have come into the market. These softwares have a different style of user task compare to existing user task. The reason why difference style has been appeared for now is because interaction timing has a important role of both content creation and consumption. For this reason, in this paper, we propose a software UI design framework for content creation using MB-UID and UCD model based on task modeling. The proposed framework is made up of five steps: business rule model, creation role model, creation flow model, creation action model, presentation model. Through this framework, we handle the interaction between a content creator and software user interface at the content creation phase. At the same time, we consider a possible interaction type which can occur by consumers at the consumption phase in advance.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.62 no.5
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• pp.696-704
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• 2013

In this paper, we introduce the LED emotional lighting system realized with the aid of both intelligent algorithm and RGB LED combined with White LED. Generally, the illumination is known as a design factor to form the living place that affects human's emotion and action in the light- space as well as the purpose to light up the specific space. The LED emotional lighting system that can express emotional atmosphere as well as control the quantity of light is designed by using both RGB LED to form the emotional mood and W LED to get sufficient amount of light. RBFNNs is used as the intelligent algorithm and the network model designed with the aid of LED control parameters (viz. color coordinates (x and y) related to color temperature, and lux as inputs, RGBW current as output) plays an important role to build up the LED emotional lighting system for obtaining appropriate color space. Unlike conventional RBFNNs, Fuzzy C-Means(FCM) clustering method is used to obtain the fitness values of the receptive function, and the connection weights of the consequence part of networks are expressed by polynomial functions. Also, the parameters of RBFNN model are optimized by using PSO(Particle Swarm Optimization). The proposed LED emotional lighting can save the energy by using the LED light source and improve the ability to work as well as to learn by making an adequate mood under diverse surrounding conditions.

• Health Policy and Management
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• v.23 no.1
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• pp.66-77
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• 2013

The purpose of this empirical study is to investigate the factors of self-leadership depending on individual characteristics, job characteristics, and qualities of leader-member exchange. Additionally, this study aims to discover the effect of self-leadership's outcome factors on organizational citizenship behavior and innovative activities. In order to verify research model and hypothesis, questionnaires were collected from department members working at general hospitals, hospitals, and clinics in metropolitan area of Seoul, which were 85 departments and 344 respondents. Collected data were analyzed with SPSS ver. 19.0 and Amos ver. 18.0 statistical package using Structural Equation Model. The results of the analysis showed that both individual characteristics and job characteristics have significant positive effect on self-leadership. Also, self-leadership had significant positive relationship on innovative action and organizational citizenship behavior. The implications of this study are as follow. First, this study empirically explained how self-leadership is applied in healthcare organizations. Second, it verified the relationship between causal factors and outcome factors of self-leadership. Also, prior researches of self-leadership have been conducted on business companies, but this study explored self-leadership at healthcare organizations, which increased external validity. Nowadays, many people are interested in the effect of leadership in order to overcome issues coming from enlarged organizations and to improve performance. Self-leadership will contribute to maximizing voluntary efforts of human resources and performance in a rapidly changing healthcare industry.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.3
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• pp.1337-1345
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• 2012

The principle of Effective Based Operation applied to the Korean Theater resulted in measurable effects to win the minimum battle. Based on the finding, this study recommends the effect analysis methodology under the V-C interoperability system to acquire a weapon system. This method is followed as below; to confirm the effect data on the organized weapon system, to set MOE, MOP and effect considering the purpose of the analysis, to apply the appropriate operational concept and scenario on the weapon system, and then the available C Model is after action reviewed, adjusted, and given feedback. The V-C interoperability system enables to perform the real-time combat experiment under the virtual synthesized battlefield circumstances. The defensive battle organization and displacement of the future anti-tank guided weapon system was considered in the modeling process. Scenario was written, which encompasses company-level units and the battalion-level operation. Then the available AWAM was embodied and effect-analyzed, which formed the foundation of SBA.

• Korean Journal of Cognitive Science
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• v.10 no.1
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• pp.1-11
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• 1999

Agent-based systems technology has generated lots of excitement in these years because of its promise as a new paradigm for conceptualizing. designing. and l implementing software systems Especially, there has been many researches for multi agent system because of the characteristics that it fits to the distributed and open Internet environments. In a multiagent system. agents must cooperate with each other through a Coordination procedure. when the conflicts between agents arise. where those are caused b by the point that each action acts for a purpose separately without coordination. But P previous researches for coordination methods in multi agent system have a deficiency that they can not solve correctly the cooperation problem between agents which have different goals in dynamic environment. In this paper. we solve the cooperation problem of multiagent that has multiple goals in a dynamic environment. with an automatic cooperative coordination model using I reinforcement learning. We will show the two pursuit problems that we extend a traditional problem in multi agent systems area for modeling the restriction in the multiple goals in a dynamic environment. and we have verified the validity of the proposed model with an experiment.