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Risk indicators related to periimplant disease: an observational retrospective cohort study

  • Poli, Pier Paolo;Beretta, Mario;Grossi, Giovanni Battista;Maiorana, Carlo
    • Journal of Periodontal and Implant Science
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    • v.46 no.4
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    • pp.266-276
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    • 2016
  • Purpose: The aim of the present study was to retrospectively investigate the influence of potential risk indicators on the development of peri-implant disease. Methods: Overall, 103 patients referred for implant treatment from 2000 to 2012 were randomly enrolled. The study sample consisted of 421 conventional-length (>6 mm) non-turned titanium implants that were evaluated clinically and radiographically according to preestablished clinical and patient-related parameters by a single investigator. A non-parametric Mann-Whitney U test or Kruskal-Wallis rank test and a logistic regression model were used for the statistical analysis of the recorded data at the implant level. Results: The diagnosis of peri-implant mucositis and peri-implantitis was made for 173 (41.1%) and 19 (4.5%) implants, respectively. Age (${\geq}65$ years), patient adherence (professional hygiene recalls <2/year) and the presence of plaque were associated with higher peri-implant probing-depth values and bleeding-on-probing scores. The logistic regression analysis indicated that age (P=0.001), patient adherence (P=0.03), the absence of keratinized tissue (P=0.03), implants placed in pristine bone (P=0.04), and the presence of peri-implant soft-tissue recession (P=0.000) were strongly associated with the event of peri-implantitis. Conclusions: Within the limitations of this study, patients aged ${\geq}65$ years and non-adherent subjects were more prone to develop peri-implant disease. Therefore, early diagnosis and a systematic maintenance-care program are essential for maintaining peri-implant tissue health, especially in older patients.

Study on the Valuation Method for Redeveloped Area of Industrial Heritage (산업 유산 재생지역에 대한 가치 평가 방법에 대한 연구)

  • Sun, Li;Pan, Young-Hwan
    • Journal of the Korea Convergence Society
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    • v.11 no.2
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    • pp.117-126
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    • 2020
  • Objective evaluation of the resources of industrial heritage regeneration area is an important prerequisite for design and improvement. The purpose of the study is to comprehensively evaluate the value of the industrial heritage regeneration area. This study identifies the method (model), combining the qualitative factor and quantitative factor. (1) Establish an evaluation system (AHP Hierarchy) based on the resources of regeneration area; (2) Choose an evaluation way based on the type of resource; (3) Calculate the value and total value of various resources in the area. The research is a case study of Canal 5 resort. It expounds the using process of the method and gets the rank and total value of each type of resource in this area, the factors influencing the value (mainly concerned with income), etc. The conclusion is that the value of the reclaimed land should be composed of both the use value and the non-use value; the same factor has different influence on different resources; different factors influence one resource to different extents.

Prognostic Value of Preoperative Serum Alpha- Fetoprotein Level in Resectable Gastric Cancer (절제 가능한 위암 환자에서 수술 전 혈청 알파태아단백치 측정의 의의)

  • Yu, Wan-Sik;Kim, Tae-Bong
    • Journal of Gastric Cancer
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    • v.3 no.1
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    • pp.33-37
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    • 2003
  • Purpose: Alpha-fetoprotein (AFP) is widely accepted as a useful tumor marker for diagnosis of hepatocellular carcinomas. On rare occasions, however, an abnormal elevation of serum AFP also has been reported in an adenocarcinoma of the gastrointestinal tract. We evaluated the influence of preoperative abnormal elevation of serum AFP (AFP positivity) on the prognosis of resectable gastric cancers. Materials and Methods: 812 gastric cancer patients, who were investigated for serum AFP before their operations and who underwent gastric resections with D2 or more extended lymph node dissection, were enrolled in the study. The survival rates were calculated by using the Kaplan-Meier method and were compared by using the log-rank test. A multivariate analysis was performed using the Cox proportional hazards model. Results: Fifty patients ($6.2\%$) were AFP positive (10.1. 4322.6 ng/ml). The survival rate of the AFP positive group was significantly lower than that of the AFP negative group ( $46.6\%\;vs.\;67.0\%$; P=0.0002). The depth of tumor invasion, the degree of regional lymph node metastasis, distant metastases, the TNM stage, the gross type, differentiation, the extent of gastric resection, and the curability of the surgery also significantly influenced survival. Multivariate analysis revealed that the depth of tumor invasion, the degree of regional lymph node metastasis, the curability of the surgery, and AFP positivity were independent prognostic indicators. Conclusion: Preoperative serum AFP can be used as an independent prognostic factor of resectable gastric cancer.

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On the Formation of Red-sequence Galaxies in Rich Abell Clusters at z ${\lesssim}$ 0.1

  • Sheen, Yun-Kyeong
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.1
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    • pp.36.2-36.2
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    • 2012
  • The aim of this study was to explore the role of galaxy mergers on the formation and evolution of galaxies in galaxy clusters. For this purpose, u', g', r' deep optical imaging and multi-object spectroscopic observation were done for four rich Abell clusters at z ${\lesssim}$ 0.1 (A119, A2670, A3330, and A389) with a MOSAIC 2 CCD and Hydra spectrograph mounted on a Blanco 4-m telescope at CTIO. With the deep images, we found that about 25% of the bright red-sequence galaxies exhibited post-merger signatures in a cluster environment. This fraction was much higher than what was expected from the results of the field environment (-35%, van Dokkum 2005) and significantly low on-going merger fractions (about one-fifth of the field) appeared in the clusters currently. Taking advantage of the most up-to-date semi-analytic model, the results indicate that most of the post-merger galaxies may have carried over their merger features from their previous halo environment. All the brightest cluster galaxies in our cluster samples revealed faint structures in their halos as well as multiple nuclei in their centers seen in the deep optical images. We suggest that the mass of the BCGs increased mainly though major mergers at recent epochs based on their post-merger signatures and the large gaps in the total magnitudes between the BCGs and the second-rank BCGs. A UV bright tidal tail and tidal dwarf galaxy (TDG) candidates around the post-merger galaxy, NGC 4922, were discovered in the outskirts of the Coma cluster using the GALEX UV data. We did two-component stellar population modeling for the TDG candidates and the results indicate that they are an early form of dwarf galaxies frequently found around massive early-type galaxies in clusters. In conclusion, we suggest that the mergers of galaxies are an important driving force behind galaxy formation and evolution in cluster environments even until recent epochs.

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p53, Cyclin D1, p21 (WAF1) and Ki-67 (MIB1) Expression at Invasive Tumour Fronts of Oral Squamous Cell Carcinomas and Development of Local Recurrence

  • Sawair, F;Hassona, Y;Irwin, C;Stephenson, M;Hamilton, P;Maxwell, P;Gordon, D;Leonard, A;Napier, S
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1243-1249
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    • 2016
  • Background: Expression of p53, cyclin D1, p21 (WAF1) and Ki-67 (MIB1) was evaluated in oral squamous cell carcinoma (OSCC) to test whether levels of these markers at invasive tumour fronts (ITFs) could predict the development of local recurrence. Materials and Methods: Archived paraffin-embedded specimens from 51 patients with T1/T2 tumours were stained immunohistochemically and analysed quantitatively. Local recurrence-free survival was tested with Kaplan-Meier survival plots (log-rank test) using median values to define low and high expression groups and with a Cox's proportional hazards model in which the expression scores were entered as continuous variables. Results: The assessment of expression of all markers was highly reliable, univariate analysis showing that patients with clear surgical margins, with low cyclin D1 and high p21 expression at the ITF had the best local recurrence-free survival. Multivariate analysis showed that these three parameters were independent prognostic factors but that neither p53 nor MIB1 expression were of prognostic value. Conclusions: Assessment of p53, cyclin D1, p21 (WAF1), and Ki-67 (MIB1) at the ITF could help to predict local recurrence in early stage oral squamous cell carcinoma cases.

Multivariate Analysis of the Prognosis of 37 Chondrosarcoma Patients

  • Yang, Zheng-Ming;Tao, Hui-Min;Ye, Zhao-Ming;Li, Wei-Xu;Lin, Nong;Yang, Di-Sheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1171-1176
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    • 2012
  • Objective: The current study aimedto screen for possible factors which affect prognosis of chondrosarcoma. Methods: Thirty seven cases were selected and analyzed statistically. The patients received surgical treatment at our hospital between December 2005 and March 2008. All of them had complete follow-up data. The survival rates were calculated by univariate analysis using the Kaplan-Meier method and tested by Log-rank. ${\chi}^2$ or Fisher exact tests were carried out for the numeration data. The significant indexes after univariate analysis were then analyzed by multivariate analysis using COX regression model. Based on the literature, factors of gender, age, disease course, tumor location, Enneking grades, surgical approaches, distant metastasis and local recurrence were examined. Results: Univariate analysis showed that there were significant differences in Enneking grades, surgical approaches and distant metastasis related to the patients' 3-year survival rate after surgery (P<0.001). No significant difference was not found in gender, age, disease course, tumor location or local recurrence (P>0.05). Multivariate analysis showed that Enneking grade (P=0.007) and surgical approaches (P=0.010) were independent factors affecting the prognosis of chondrosarcoma, but distant metastasis was not (P=0.942). Conclusion: Enneking grades, surgical approaches and distant metastasis are risk factors for prognosis of chondrosarcoma, among which the former two are independent factors.

Long-Term Outcomes after D2 Gastrectomy for Early Gastric Cancer: Survival Analysis of a Single-Center Experience in China

  • Wang, Zheng;Ma, Li;Zhang, Xing-Mao;Zhou, Zhi-Xiang
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.17
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    • pp.7219-7222
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    • 2014
  • Background: Early gastric cancer (EGC) is well accepted as having a favorable prognosis, but some patients experience an ominous outcome after curative resection. This study was aimed at evaluating predictive factors associated with prognosis of D2 gastrectomies in patients with early gastric cancer. Materials and Methods: A total of 518 patients with early gastric cancer who underwent D2 gastrectomies were reviewed in this study. The clinicopathological features and surgical outcomes were analyzed. The survival rate was estimated using the Kaplan-Meier method and compared by log rank test. Prognostic factors were analyzed using a multivariate Cox proportional hazards model. Results: The 5-year survival rate was 90.3%. Tumor infiltration, lymph node metastasis and lymphovascular invasion were significant prognostic factors for survival. Gender, age, tumor size, tumor location, macroscopic type and histological type were not significant prognostic factors. Multivariate analysis indicated that lymph node metastasis was an independent poor prognosis factor. Conclusions: Early gastric cancers with lymph node metastasis have a relatively poor prognosis after standard surgery. Even after curative resection, patients with EGC with positive lymph nodes should be closely followed and be considered as candidates for comprehensive therapies.

Evaluation of Dimensional Stability of Digital Dental Model Fabricated by Impression Scanning Method (인상 스캐닝 방법에 의해 제작된 디지털 치과 모형의 체적 안정성 평가)

  • Kim, Jae-Hong;Kim, Ki-Baek
    • Journal of dental hygiene science
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    • v.14 no.1
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    • pp.15-21
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    • 2014
  • The purpose of this study in vitro investigation was to evaluate the dimensional stability of dental digital models made by impression scanning method. Twenty working models were produced. Twenty impressions were made from study models. The dimensional stability of models of two groups (stone and digital models) was examined using six landmark distances. Stone models were measured through digital vernier calipers. Digital models were measured by the computer program. Statistical analyses were performed with Wilcoxon rank sum test (${\alpha}=0.05$). The mean of six landmark distances were significantly larger in the stone models than in the digital models (p<0.05) but digital models showed clinically acceptable accuracy.

Vegetation Classification and Biomass Estimation using IKONOS Imagery in Mt. ChangBai Mountain Area (IKONOS 위성영상을 이용한 중국 장백산 일대의 식생분류 및 바이오매스 추정)

  • Cui, Gui-Shan;Lee, Woo-Kyun;Zhu, Wei-Hong;Lee, Jongyeol;Kwak, Hanbin;Choi, Sungho;Kwak, Doo-Ahn;Park, Taejin
    • Journal of Korean Society of Forest Science
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    • v.101 no.3
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    • pp.356-364
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    • 2012
  • This study was to estimate the biomass of Mt. Changbai mountain area using the IKONOS imagery and field survey data. Then, we prepared the regression function using the vegetation index derived from the IKONOS and biomass estimated from field measured data of previous studies, respectively. The five vegetation index which used in the regression model was SAVI, NDVI, SR, ARVI, and EVI. As a result, the rank of the R-square from coefficient of correlation was as follow, SAVI(0.84), NDVI(0.73), SR(0.59), ARVI(0.0036), EVI(0.0026). Finally, we estimated the biomass of non-measured area using the Soil Adjusted Vegetation Index (SAVI). This study can be used as reference methodology for the estimation of carbon sinks of primary forest.

Model Development of Illness Perception and Consequences in Breast Cancer Patients

  • Hoseini, L;Kashani, F Lotfi;Akbari, S;Akbari, ME;Mehr, S Sarafraz
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.sup3
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    • pp.185-190
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    • 2016
  • Breast cancer is the first or second malignancy among women worldwide. Illness perception (IP) and quality of life (QoL) are major issues considering breast cancer management. An attempt was here made to inspect the predictive variables influencing IP and their impact on QoL in cancer patients. The key predictors adapted from previous studies including life satisfaction, perceived social support, self-esteem, hope, optimism, and spiritual well being were taken into account. Our sample included 200 female volunteers suffering from breast cancer applying exclusion criteria. The data were collected using various questionnaires and statistically analyzed by means of path analysis and structural equation modeling. The results revealed that of the six predictors, spiritual well being and social support had direct effects on QoL and IP. The only path with significant indirect correlation with IP was social support. Spiritual well being had the second significant direct effect on IP. Self-esteem occupied the third rank in direct effects on both QoL and IP. In conclusion, here in Iran and most likely in other strongly religious communities, spiritual intervention is an effective strategy to raise QoL. Also social support helps women suffering from breast cancer to experience better conception and coping strategies.