• Asian Pacific Journal of Cancer Prevention
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• v.17 no.1
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• pp.45-50
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• 2016

Background: The tobacco epidemic is a heralding health menace, particularly among college students. Tobacco usage among young can have an especially devastating effect as they can be exposed for longer periods. Data to estimate the prevalence of tobacco use in young adults will be a valuable addition to the existing resources. Materials and Methods: An analytical cross-sectional study was therefore carried out in Mangalore city using a pre-tested, self-administered questionnaire adapted from the Global Youth Tobacco Survey (GYTS) with a representative sample of 720 students aged 18-20 years selected from degree colleges by multi-stage random sampling. Results: Prevalence of 'ever users' and 'current users' of smoking were 20.4% and 11.4%, respectively. The mean age at initiation of cigarette smoking was 16 years and the majority (31 %) smoked in public places. Interestingly, 84% of them knew about the harmful effects of cigarette smoking. About one half of smokers had some or most of their friends smoking. Multivariate analysis revealed gender (OR=8.585: CI-3.26-22.5), pocket money (OR=4.165; CI=1.76-9.82) and peer's smoking habit (OR= 5.15; CI-2.21-11.9) have higher odds as correlates of tobacco usage among college students. Conclusions: It is of prime importance to highlight the role of prevention of smoking initiation rather than subsequently trying to stop the habit. Comprehensive interventions embracing family, friends and social milieu are needed to reduce tobacco use among students in India.

• Journal of Wetlands Research
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• v.6 no.1
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• pp.89-104
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• 2004

In the aftermath of nation-wide controversy over "conservation vs. development" of the costal wetland in the Saemangeum, Korea could legislate the laws of wetland conservation and costal management in 1998. Since then, the public interest in the costal mudflats and its conservation has increased greatly, but the controversy on the economic value of mutflat wetland and the futher (un)necessity of reclamation) is not yet settled. In the cases of Korea dealt, economic valuation of wetland was performed mainly in the milieu of reclamation(development) vs conservation conflict, or from interest of recreational use. Korean studies used to estimate economic value of development case and conservation case respectively and then tried to compare these two value, as is sometimes done also in other countries. But the scrutiny of the results of these studies leads us to conclude that the revealed wide discrepancy among estimated values, above all other methodological problems, denies any practical applicability to the actual policy use. Benefit transfer as a convenient alternative method of valuation can not be usable either in our cases, because there is too few reliable estimated economic values of mudflat wetlands.

• Journal of Microbiology and Biotechnology
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• v.17 no.9
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• pp.1521-1526
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• 2007

A maltogenic amylase gene from Lactobacillus gasseri ATCC33323 (LGMA) was expressed in Lactococcus lactis MG1363 using the P170 expression system. The successful production of recombinant LGMA (rLGMA) was confirmed by the catalytic activity of the enzyme in liquid and solid media. The N-terminal amino acid sequencing analysis of the rLGMA showed that it was Met-Gln-Leu-Ala-Ala-Leu-, which was the same as that of genuine protein, meaning the signal peptide was efficiently cleaved during secretion to the extracellular milieu. The optimal reaction temperature and pH of rLGMA ($55^{\circ}C$ and pH 5, respectively) and enzymatic hydrolysis patterns on various substrates (${\beta}$-cyclodextrin, starch, and pullulan) supported that rLGMA was not only efficiently secreted from the Lactococcus lactis MG1363 but was also functionally active. Finally, the branched maltooligosaccharides were effectively produced from liquefied com starch, by using rLGMA secreted from Lactococcus lactis, with a yield of 53.1%.

• 한국해양학회지
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• v.30 no.4
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• pp.271-278
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• 1995

A study of heavy mineral sands in terms of heavy mineral group and concentration has been carried out by analyzing 88 grab samples from the continental shelf off the southeast coast of Korea. Heavy mineral groups seem to be outlined and classified into four regions in the study area: 1) the western region; high concentrations of stable minerals, such as opaque mineral, magnetite, garnet and ZTR, 2) Korean Trough region; moderate concentrations of stable minerals, 3) the eastern region; abundant altered mineral and amphibole with minor of pyroxene concentration, and 4) the northeastern shelf-break region; low concentration of stable minerals with abundant altered minerals. The sedimentologic natures of four major heavy mineral regions (groupings) seem to be influenced by physical, dynamic and hydraulic milieu and also aerial and/or subaqueous weathering processes. It seems to be, further, plausible that shallow marine waves and currents associated with neritic dynamic condition of transgressive sea might be very effective on the concentration and groupings (sorting) of heavy min-erals in the surficial sediments of the continental shelf. The pyroxene-abundant heavy mineral suite (group), in fact, seems to suggest a sediment source from Japanese Islands.

• Toxicological Research
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• v.34 no.3
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• pp.241-247
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• 2018

Lactobacillus (LAB) have been reported to exert both harmful and beneficial effects on human and animal health. Recently, it has been reported that dysbiosis and bacterial translocation contribute to liver fibrosis. However, the role of Gram-positive LAB in the situation of chronic liver diseases has not been yet elucidated. Liver injury was induced by bile duct ligation (BDL) in LAB or control-administered mice. Liver fibrosis was enhanced in LAB-administered mice compared with control-treated mice as demonstrated by quantification of Sirius-red positive area, hydroxyproline contents and fibrosis-related genes ($Col1{\alpha}1$, Acta2, Timp1, Tgfb1). Moreover, LAB-administered mice were more susceptible to BDL-induced liver injury as shown by increased ALT and AST level of LAB group compared with control group at 5 days post BDL. Consistent with serum level, inflammatory cytokines ($TNF-{\alpha}$, IL-6 and $IL-1{\beta}$) were also significantly increased in LAB-treated mice. Of note, LAB-treated liver showed increased lipoteichoic acid (LTA) expression compared with control-treated liver, indicating that LAB-derived LTA may translocate from intestine to liver via portal vein. Indeed, responsible receptor or inflammatory factor (PAFR and iNOS) for LTA were upregulated in LAB-administered group. The present findings demonstrate that administration of LAB increases LTA translocation to liver and induces profibrogenic inflammatory milieu, leading to aggravation of liver fibrosis. The current study provides new cautious information of LAB for liver fibrosis patients to prevent the detrimental effect of LAB supplements.

• Journal of Animal Science and Technology
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• v.59 no.1
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• pp.1.1-1.11
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• 2017

Background: Intrauterine environment plays a pivotal role in the origin of fatal diseases such as the metabolic syndrome. Diabetes is associated with low-grade inflammatory state and dysregulated adipokines production. The aim of this study is to investigate the effect of maternal diabetes on adipocytokines (adiponectin, leptin and TNF-${\alpha}$) production in F1 offspring in rats. Methods: The offspring groups were as follows: F1 offspring of control mothers under control diet (CD) (CF1-CD), F1 offspring of control mothers under high caloric diet (HCD) (CF1-HCD), F1 offspring of diabetic mothers under CD (DF1-CD), and F1 offspring of diabetic mothers under HCD (DF1-HCD). Every 5 weeks post-natal, 10 pups of each subgroup were culled to obtain blood samples for biochemical analysis. Results: The results indicate that DF1-CD and DF1-HCD groups exhibited hyperinsulinemia, dyslipidemia, insulin resistance and impaired glucose homeostasis compared to CF1-CD (p > 0.05). DF1-CD and DF1-HCD groups had high hepatic and muscular depositions of TGs. The significant elevated NEFA level only appeared in offspring of diabetic mothers that was fed HCD. DF1-CD and DF1-HCD groups demonstrated low serum levels of adiponectin, high levels of leptin, and elevated levels of TNF-${\alpha}$ compared to CF1-CD (p > 0.05). These results reveal the disturbed metabolic lipid profile of offspring of diabetic mothers and could guide further characterization of the mechanisms involved. Conclusion: Dysregulated adipocytokines production could be a possible mechanism for the transgenerational transmittance of diabetes, especially following a postnatal diabetogenic environment. Moreover, the exacerbating effects of postnatal HCD on NEFA in rats might be prone to adipcytokine dysregulation. Furthermore, dysregulation of serum adipokines is a prevalent consequence of maternal diabetes and could guide further investigations to predict the development of metabolic disturbances.

• Journal of the Economic Geographical Society of Korea
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• v.23 no.1
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• pp.110-123
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• 2020

The advanced industrial economies have been suffering from rapid de-industrialization since the 1970s. In order to overcome such crisis, many countries have attempted to establish science parks and technopoles. Sophia Antipolis in France is one of the best examples of the worldly known technopoles, which was launched in the late 1960s. However, earlier evaluations on the technopole were not positive, while there were no dynamic innovative activities among institutions and firms of the technopole at least up to the early 1990s. While some changes in such circumstance have been observed since then, this paper attempts to investigate the changes and transformations occurring from the technopole since the late 1990s. Based on the review of the recent publications, statistics and expert interviews, the current paper concludes that Sophia Antipolis has been transformed into a dynamic and innovative technopole.

• Korean Institute of Interior Design Journal
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• v.16 no.4
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• pp.110-118
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• 2007

Technology has been viewed at various stages of civilization as leading to future progress. The building, its services systems and management of the work process all contribute to the well-being of people within an organization. Productivity relies on there being a general sense of high morale and satisfaction with the workplace. Now buildings are considered as providing a milieu for human creativity. Flexibility, adaptability, service integration and high standards of finishes offer an intelligence threshold. Building Automation System(BAS) - controlled lighting systems may offer incremental energy saving. Conventional Lighting control systems often control equipment in a single room or over the limited area, because they are centralized control systems, which means that all the controlled circuits must be wired to a single control panel. The computers used by these systems are typically dedicated microprocess that perform only lighting control functions. By comparison, modern Building automation systems are distributed control system, which means that their computing hardware and software are distributed as a network that microprocessor-based control modules and standard PC. PLC(Programmable Logic controller) is extensible virtually without limits, so that all the lighting in a facility can be controlled by single, unified system - the same system that also can control and monitor the building's HVAC, security, and manufacturing processed, elevators, and more. A Building automation system can control light using schedules, manual controls, occupancy sensors, and photosensors, either singly or in combination. Building Lighting control and monitoring system will be for a energy saving and efficient building management system.

• Archives of design research
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• no.16
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• pp.237-252
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• 1996

Study of new materials, which has been going on in many fields of modem art since the beginning of this century, has cintributed much to the development of modem art. In this regard, it is noteworthy that many in the field of fiber art have experimented with non-traditional, indusrial materials with some notable success. Industrial materials represent the world of thechnology we live in and help us form the kind of view on art that is reflective of the present age and its social milieu. Industrial materials, when used as media for art, also present us with new concepts and possibilities for artistic expression. In fiber art, the use of industrial materials has greatly expanded the very idea of 'fiber', effectively ferring the imagination of fiber aetists to experiment with diverse materials and new mathodology. Overcoming the traditional constraints of technique-orienthd their discipline, fiber artists began to pay more attention to matiere or the material jtself and the infinite variety of surface, color and texture that it promises. And informed by this newly discovered aesthetice of the material. fiber artists began in eamest to expand the area of their artistic expression, producing multi-dimensional works, conquering space and experimentiong with hugc environmantal works.

• Journal of Navigation and Port Research
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• v.35 no.6
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• pp.539-550
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• 2011

Hamburg is going with the HafenCity Project to create a new urban space for the city's bustling central district. HafenCity will add an additional 155 hectares to Hamburg's central urban area, increasing it's total area by some 40 percent. The qualities of the HafenCity are mainly marked through the location at the water, the river Elbe and the historically embossed milieu the Speicherstadt. A tightly mix of residential accommodation, offices, cultural and leisure amenities, retail facilities and restaurants manages diverse identities of quarters in a framework of an elaborate urban layout. This study is focusing on the purpose of the project goals, the task of the Hamburg authorities and GHS (Gesellschaft fur Hafen und Standortentwicklung) and an urban planning ideas competition (draft masterplan). Regarding of the new trend of the reurbanisation in Europe, the aim of this study is to find out, in which way HafenCity is trying to develope the new city district as a model for the European port city of the 21st century.