• 제목/요약/키워드: miR-21

검색결과 501건 처리시간 0.024초

간호대학생의 자기결정성이 자기주도학습능력에 미치는 영향: 학업적 자기효능감의 매개효과를 중심으로 (Mediation Effects of Academic Self-efficacy on the Relationship between Self-determination and Self-directed Learning in Nursing Students)

  • 한미라;류정림;김신희
    • 한국학교ㆍ지역보건교육학회지
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    • 제23권2호
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    • pp.39-50
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    • 2022
  • Objectives: This study aimed to confirm the association between self-determination and self-directed learning among Korean nursing students, as well as the mediating effect of academic self-efficacy. Methods: Data from 139 nurse students were surveyed in this descriptive cross-sectional study. They were collected from Oct 1 to 30, 2020, using self-report questionnaires. The collected data were analyzed using descriptive statistics, independent t-test, one-way analysis of variance, Scheffé test, Pearson's correlation coefficient analysis, and mediated model for PROCESS macro using the SPSS/WIN 24.0. Results: Self-directed learning was positively associated with self-determination (r=.56, p<.001) and academic self-efficacy (r=.63, p<.001). Furthermore, academic self-efficacy had a mediating effect on the relationship between self-determination and self-directed learning (B=0.21, 95% CI=0.12~0.32). Conclusion: The impact of self-determination on the self-directed learning among nursing students was mediated by academic self-efficacy. Therefore, these results provide important data for future self-directed learning in nursing education.

보육교사의 우울에 영향을 미치는 요인 (Factors Influencing Depression in Child Day Care Center's Teachers)

  • 이영란;박선남;이미란
    • 한국보건간호학회지
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    • 제37권1호
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    • pp.43-53
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    • 2023
  • Purpose: This study aims to identify the factors influencing the depression of teachers in child day care centers. Methods: The study 181 teachers working at national/public or child day care centers certified by Seoul Metropolitan government in Seoul, South Korea. Data from September to October 2021, and emotional labor, job stress, ego resilience, stress resilience, and depression. Data were analyzed using t-test, ANOVA, Pearson's correlation coefficients, and stepwise multiple regression. Results: The average depression of child day care center's teachers 8.52±7.58 out of 60 points, and the depression group (above 21 points) was 9.4%. Depression in child day care center's teachers was positively correlated with job stress (r=.42, p<.001) and negatively correlated with ego resilience and stress resilience (r=-.55, p<.001). Factors affecting depression of child day care center's teachers were found to be job stress (p=0.005), ego resilience (p<.001), stress resilience (p=0.031) and the explanatory power of these variables was 39%. Conclusion: Results of this study indicate that in the future development of depression intervention programs for teachers of child day care centers, it is necessary to include measures that reduce job stress and strengthen ego resilience and stress resilience.

폐수처리장의 바이오 필터로부터 분리된 Comamonas sp. NLF-7-7 균주의 유전체 염기서열 해독 (Complete genome sequence of Comamonas sp. NLF-7-7 isolated from biofilter of wastewater treatment plant)

  • 김동현;한국일;권해준;김미경;김영국;최두호;이근철;서민국;김한솔;이정숙;김종국
    • 미생물학회지
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    • 제55권3호
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    • pp.309-312
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    • 2019
  • 본 연구에서는 폐수처리장의 바이오필터로부터 Comamonas sp. NLF-7-7 균주를 분리하고 유전체서열을 PacBio RS II와 Illumina HiSeqXten 플랫폼을 사용하여 분석하였다. 염색체의 크기는 3,333,437 bp로 G + C 구성 비율은 68.04%, 총 유전자수는 3,197개, rRNA는 9개 및 tRNA는 49개로 구성되었다. 본 유전체는 오염물질분해와 플록형성에 관여하는 황산화 경로 유전자(SoxY, SoxZ, SoxA 및 SoxB)와 플록형성 경로 유전자(EpsG, EpsE, EpsF, EpsG, EpsL 및 glycosyltransferase)를 포함하고 있다. 이러한 Comamonas sp. NLF-7-7 균주는 폐수를 정화하는데 활용될 수 있다.

VvpM Induces Human Cell Death via Multifarious Modes Including Necroptosis and Autophagy

  • Lee, Mi-Ae;Kim, Jeong-A;Shin, Mee-Young;Lee, Jeong K.;Park, Soon-Jung;Lee, Kyu-Ho
    • Journal of Microbiology and Biotechnology
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    • 제25권2호
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    • pp.302-306
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    • 2015
  • VvpM, one of the extracellular metalloproteases produced by Vibrio vulnificus, induces apoptotic cell death via a pathway consisting of ERK activation, cytochrome c release, and activation of caspases-9 and -3. VvpM-treated cells also showed necrotic cell death as stained by propidium iodide (PI). The percentage of PI-stained cells was decreased by pretreatment with Necrostatin-1, indicating that VvpM-mediated cell death occurs through necroptosis. The appearance of autophagic vesicles and lipidated form of light-chain-3B in rVvpM-treated cells suggests an involvement of autophagy in this process. Therefore, the multifarious action of VvpM might be one of the factors responsible for V. vulnificus pathogenesis.

신규간호사의 DISC 행동유형이 직무만족과 업무수행능력에 미치는 영향 (Impact of DISC Behavioral Styles on Job Satisfaction and Clinical Competencies among Newly Hired Nurses)

  • 문미영;황선영
    • 간호행정학회지
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    • 제21권1호
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    • pp.43-52
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    • 2015
  • Purpose: In this study, behavioral styles of Dominance, Influence, Steadiness, and Conscientiousness (DISC) were examined and differences in job satisfaction and clinical competence among newly hired nurses were explored. Methods: For this explanatory correlational research, 176 newly hired clinical nurses were recruited from three university hospitals and one general hospital located in Seoul and Gyeonggi province. Data were collected in August, 2013 though self-report questionnaires. Results: The distribution of behavioral styles was 11.4%, 42%, 29% and 17.6% for Dominance, Influence, Steadiness, and Conscientiousness respectively. DISC behavioral styles were associated with sub-areas of job satisfaction such as professional position and doctor-nurse relationship. DISC behavioral styles were significantly associated with the total score for clinical competence and sub-areas of data collection, basic nursing skills, critical thinking, education and leadership, and attitudes toward professional development and practical skills. Multiple linear regression analysis showed that DISC behavioral styles predicted clinical competence (Adj. $R^2$=.14, F=9.42, p<.001). Conclusion: A focus on cultivating influential and steady behavioral styles among newly hired nurses can be helpful in improving job satisfaction and clinical competence. There is a need to improve interpersonal relationships through a deeper understanding of each person's behavioral style based on the analysis of DISC behavioral styles.

중소병원 간호사의 직무 스트레스와 임파워먼트가 간호업무성과에 미치는 영향 (Influence of Job Stress and Empowerment on Clinical Nurses' Performance in Small and Medium Hospitals)

  • 김영미;이여진
    • 한국직업건강간호학회지
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    • 제21권3호
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    • pp.258-265
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    • 2012
  • Purpose: The purpose of this study is to identify the influence of job stress and empowerment on nursing performance of clinical nurses working in small and medium hospital. Methods: The empirical data were collected from a self-administered survey using a structured questionnaire with 404 nurses working in 4 medium-sized hospitals (less than 300 beds), located in I-city. The data were analyzed using stepwise multiple regression with the SPSS/WIN 17.0 program. Results: There were significant differences in nursing performance depending on general characteristics (age, marital status, religion, shift work, education level, position, clinical experience, department, and monthly salary). Empowerment correlated with nursing performance. Factors influencing on nursing performance were empowerment, clinical experience, job stress, and marital status with $R^2$ value of 36.3%. The most influencing factor was empowerment (${\beta}$=.47), followed by clinical experience (${\beta}$=.24), job stress (${\beta}$=.20), and marriage (${\beta}$=.12). Conclusion: It is needed to implement specific empowerment strategy, control job stress, and reward experienced and married nurses working in medium-sized hospital for improving nursing task performance.

한국형 중환자간호 분류도구 개발 (Development of Korean Patient Classification System for Critical Care Nurses)

  • 유정숙;심미영;최은하
    • 임상간호연구
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    • 제21권3호
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    • pp.401-411
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    • 2015
  • Purpose: This study was performed to develop a valid and reliable Korean Patient Classification System for Critical Care Nurses (KPCSC). Methods: Tertiary and general hospitals with various levels of ICU nurse staffing were included. To verify interrater reliability, data collectors and staff nurses of 15 ICUs in 11 hospitals classified 262 patients. To verify construct validity, the staff nurses classified 457 patients according to KPCSC comparing difference by medical department and type of stay in ICU. For conversion index, 195 patients from 10 ICUs in 7 hospitals were classified and nursing time was measured by 174 nurses, 7 head nurses, 18 charge nurses, 37 nurse aids and 1 secretary. Results: The developed KPCSC has 11 categories, 82 nursing activities and 115 criterias. Reliability was found to have high agreement (r=.96). Construct validity was verified by comparing differences in medical department and type of stay in ICU. According to scores, four groups in the KPCSC were identified. One score on the KPCSC indicates 6.12 minutes of nursing time. Conclusion: The findings show that the KPCSC can be used to measure new and complex nursing demands including rehabilitation and the safety of ICU patients.

Characterization of Microbial Fuel Cells Enriched Using Cr(VI)-Containing Sludge

  • Ryu, Eun-Yeon;Kim, Mi-A;Lee, Sang-Joon
    • Journal of Microbiology and Biotechnology
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    • 제21권2호
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    • pp.187-191
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    • 2011
  • Microbial fuel cells (MFCs) were successfully enriched using sludge contaminated with Cr(VI) and their characteristics were investigated. After enrichment, the charge of the final 10 peaks was 0.51 C ${\pm}$ 1.16%, and the anodic electrode was found to be covered with a biofilm. The enriched MFCs removed 93% of 5 mg/l Cr(VI) and 61% of 25 mg/l Cr(VI). 16S rDNA DGGE profiles from the anodic electrode indicated that ${\beta}$-Proteobacteria, Actinobacteria, and Acinetobacter sp. dominated. This study is the first to report that electrochemically active and Cr(VI)-reducing bacteria could be enriched in the anode compartment of MFCs using Cr(VI)-containing sludge and demonstrates the Cr(VI) removal capability of such MFCs.

물리치료 환경에 대한 근육뼈대계 및 신경계 환자의 환자만족도와 재활동기의 상관성 (Correlation between Patient Satisfaction and Rehabilitation Motivation on Musculoskeletal and Neurological Patients in a Physical Therapy Environment)

  • 김충유;김현수;김성하;도현진;양미진
    • 대한통합의학회지
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    • 제12권1호
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    • pp.151-159
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    • 2024
  • Purpose : This study was conducted to investigate correlation between patient satisfaction and rehabilitation motivation in a physical therapy environment. Methods : This study conducted a survey on musculoskeletal and neurological patients receiving rehabilitation treatment at a hospital. The subjects of the study were patients who were currently receiving rehabilitation treatment, either hospitalized or outpatient. 234 people were collected. A questionnaire was consisted of a total of 55 questions, including 27 questions about motivation for rehabilitation, 14 questions about physical therapy service environment, and 14 questions about patient satisfaction and intention to revisit. The detailed items in rehabilitation motivation consisted of 8 questions about task-oriented motivation, 7 questions about change-oriented motivation, 4 questions about obligatory motivation, 4 questions about external motivation, and 4 questions about intrinsic motivation, and in the physical therapy service environment, 4 questions about facility service and therapist service. , 6 questions, 4 questions about services used, 3 questions about friendliness, 4 questions about professionalism, 3 questions about treatment satisfaction, and 2 questions each about repeat visit and recommendation. Results : Facility service (r=.21) was highly correlated for task-oriented motivation, therapist service (r=.22) for change-oriented motivation, therapist service (r=.31) for mandatory motivation, therapist service (r=.19) for external motivation, and facility service (r=.56) for internal motivation. Revisit for task-oriented motivation (r=.47) is kind to change-oriented motives (r=-.13) was highly correlated with kindness (r=.19) for mandatory motives, recommendation (r=.14) for external motives, and expertise (r=.52) for internal motives. There was a high correlation between professionalism (r=.61) for facility services and kindness (r=.53) for therapist services, and revisit (r=.40) for service use. Conclusion : According to the results of this study, it was found that there was a correlation between patient satisfaction and rehabilitation motivation in a physical therapy environment.

물벼룩(Daphnia magna)에 대한 중금속의 급성 및 만성 독성 (Acute and Chronic Toxicity of heavy Metals to Daphnia magna)

  • 정재원;차미선;조순자;이상준
    • 한국환경과학회지
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    • 제10권4호
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    • pp.293-298
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    • 2001
  • The toxicity values heavy metals were evaluated by immobilization and chronic reproduction impairment tests, using Daphnia magna. Acute tests were evaluated by the inhibition of their mobilization after 24hrs without food addition. The tests of reproductive impairment were investigated for 21 days by food addition and exchange or water. The effect of each concentration was assessed by Probit analysis and t-test. The results obtained from this study were as follows : 1) The change of pH and DO was not significant in the acute tests, while, in the reproductive tests, pH was increased by 0.3~1.4 and DO also increased. 2) The $E_iC_{50}$ values of immobilization to Daphnia magna in artificial fresh water were $0.030mg/{\ell}(Cu),\;0.054mg/{\ell}(Cd),\;0.12mg/{\ell};(Cr),\;0.74mg/{\ell}(Pb),\;3.4mg/ {\ell}(As)$ and the $NOE_iC$ values were $0.010mg/{\ell}(Cu),\;0.018mg/{\ell}(Cd),\;0.010mg/{\ell}(Cr),\;0.10mg/{\ell}(Pb),\;and\;$1.8mg/{\ell}(As)$. 3) The $E_rC_{50}$ values of reproductive impairment to Daphnia magna were $13.8\mu\textrm{g}/{\ell}(Cu),\;2.9\mu\textrm{g}/{\ell}(Cd),\;15.5\mu\textrm{g}/{\ell}(Cr),\;61.7\mu\textrm{g}/{\ell}(Pb),\;759\mu\textrm{g}/{\ell}(As)$, and $NOE_rC$ values were $0.95\mu\textrm{g}/{\ell}(Cu),\;$0.54\mu\textrm{g}/{\ell}(Cd),\;1.2\mu\textrm{g}/{\ell}(Cd),\;$7.4\mu\textrm{g}/{\ell}(Pb),\;110mu\textrm{g}/{\ell}(As)$. The results of tests using OECD artificial culture water were more sensitive than natural water for culturing. The presented data show that an artificial culture water is suitable in the experiment of bioassay for assessing the toxicity of marterials.

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