• Korean Journal of Construction Engineering and Management
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• v.13 no.6
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• pp.94-106
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• 2012

In recent years, the risks and uncertainties associated with mixed used development in urban regeneration projects which have actively been implemented at home and abroad have been on the rise due to the uncertainties of the initial business plan, difficulty of financing, increase in total cost and schedule delay. To cope with rapid social and economic changes and optimize benefits, a risk-based configuration management process that considers life cycle is required, along with accurate planning in the early stage of the business. In addition, it is necessary to prepare measures that can respond to the evaluation and measurement of the configuration factors in relation to the business process. However, the focus of previous studies on configuration management in the field of construction was mainly on humanities and the sociological aspects such as organization, leadership, ideology and similar concepts. There has been limited research on the process and measurement and evaluation methods for configuration factors required in decision-making on the risks and changes that can occur in the actual project implementation phase. Accordingly, in this study, we defined risk-based configuration factors and developed a process and MECA/3DAM/CII methodology to measure and evaluate these factors so as to carry out systematic configuration management of mixed used development in urban regeneration projects.

• Korean Journal of Pharmacognosy
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• v.37 no.2 s.145
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• pp.103-109
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• 2006

Advanced glycation end products (AGEs) formation plays an important role in the progression of diabetic complications. To develop effective herbal formulations with suppression of diabetic nephropathy, a common complication in diabetic patients, we evaluated inhibitory activities of KIOM-79, a new herbal prescription, on the formation of AGEs using in vitro and in vivo model systems. Effects of KIOM-79 on the expression of AGEs, RAGEs (receptor for Advanced glycation end products), type IV collagen and renal $TGF-{\beta}1$ mRNA was also examined in streptozotocon (STZ)-induced diabetic rats. STZ-induced diabetic rats were treated orally with KIOM-79 (250 and $500\;kg^{-1}$ once a day for 13 weeks). In vitro system KIOM-79 suppressed the formation of AGEs $(18.12\;{\mu}g/ml)$. In STZ-induced diabetic rats showing accumulation of AGE and RAGE, pathological examination revealed that KIOM-79 prevented AGE and RAGE deposition in the kidney. In STZ induced diabetic rats, the expansion of mesangial matrix and the glomerular tufts seemed to be larger than those in normal rats. Howεver, after administration with KIOM-79, mesangial metrix and glomerular volume were decreased, and overexpression of type IV collagen was also decreased. Overexpression of renal $TGF-{\beta}1$ mRNA was inhibited significantly. These results suggest that the KIOM-79 might be an effective herbal prescription to prevent or alleviate the progression of diabetic nephropathy.

• The Korean Journal of Quaternary Research
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• v.18 no.1 s.22
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• pp.1-20
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• 2004

A geoscientific research was performed on 12 samples of comb-pattern potteries which were excavated at Daecheonri neolithic site, Korea. The texture and compositions of 12 potteries and surrounding metrix of soil and rocks were compared with the help of petrographic microscope, XRD and REE data. As to the manufacturing techniques thick potteries are caused by the amount and number of coarse grains which are assumed to be added shards when their distributional pattern are considered. DC1, DC3, DC 7 and DC11 samples have clearly oriented textures, and the orientation of vesicles in DC3 and DC11 samples arranged in the same direction with those on the pottery surface. This indicates the use potter's wheel technique in manufacturing potteries. Burning temperature is assumed over $800^{/circ}C$, particularly under reduction environment. As to the source, raw materials of pottery matrix are derived from the bottom of excavation site, or in an extracted outcrop of the northwestern foothill from site, while the shard materials are very similar with those extracted from sandy loams near sites. Finally any use pattern of pottery may control the pottery thickness, shard addition, and matrix selection.

• Tunnel and Underground Space
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• v.17 no.2 s.67
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• pp.139-151
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• 2007

Stereophotogrammetry is a method to extract information of an interested area by constructing a stereo-image from two or more photos. In this study, the stereophotogrammetry was adopted to obtain the joint orientation and trace length from a sampling window and its measurements were compared with the result by a clinocompass and measuring tape to evaluate the applicability of the stereophotogrammetry to rock joint survey. A commercial stereophotogrammetry program, ShapeMetriX 3D, was used for this purpose. Firstly, the accuracy of the measuring method using ShpaeMetrix 3D was evaluated by a model test. Secondly, joint orientations on a rock slope and tunnel were obtained by using ShapeMetriX 3D and compared with the measurement by a clinocompass. Finally. the effect of base-depth ratio in photographing was evaluated by comparing images with various base-depth ratios, and the usefulness of closed-up photographing on a rock exposure to increase the measurement accuracy was tested. The dip and dip direction of each model plane obtained by ShapeMetriX 3D showed an error ranged between $-5^{\circ}\;and\; 5^{\circ}$ on the basis of the results by the measuring tape. Base-depth ratio proved not to influence the analysis result by ShapeMetriX 3D if all the images were taken without any hidden area. The close-up photographing turned out useful to obtain the detailed images and therefore precise result when ShapeMetriX 3D was adopted.