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Ex vivo Morphometric Analysis of Coronary Stent using Micro-Computed Tomography (미세단층촬영기법을 이용한 관상동맥 스텐트의 동물 모델 분석)

  • Bae, In-Ho;Koh, Jeong-Tae;Lim, Kyung-Seob;Park, Dae-Sung;Kim, Jong-Min;Jeong, Myung-Ho
    • Journal of the Korean Society of Radiology
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    • v.6 no.2
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    • pp.93-98
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    • 2012
  • Micro-computed tomography (microCT) is an important tool for preclinical vascular imaging, with micron-level resolution. This non-destructive means of imaging allows for rapid collection of 2D and 3D reconstructions to visualize specimens prior to destructive analysis such as pathological analysis. Objectives. The aim of this study was to suggest a method for ex vivo, postmortem examination of stented arterial segments with microCT. And ex vivo evaluation of stents such as bare metal or drug eluting stents on in-stent restenosis (ISR) in rabbit model was performed. The bare metal stent (BMS) and drug eluting stent (DES, paclitaxel) were implanted in the left or right iliac arteries alternatively in eight New Zealand white rabbits. After 4 weeks of post-implantation, the part of iliac arteries surrounding the stent were removed carefully and processed for microCT. Prior to microCT analysis, a contrast medium was loaded to lumen of stents. All samples were subjected to an X-ray source operating at 50 kV and 200 ${\mu}A$ by using a 3D isotropic resolution. The region of interest was traced and measured by CTAN analytical software. Objects being exposed to radiation had different Hounsfield unit each other with values of approximately 1.2 at stent area, 0.12 ~ 0.17 at a contrast medium and 0 ~ 0.06 at outer area of stent. Based on above, further analyses were performed. As a result, the difference of lengths and volumes between expanded stents, which may relate to injury score in pathological analysis, was not different significantly. Moreover, ISR area of BMS was 1.6 times higher than that of DES, indicating that paclitaxel has inhibitory effect on cell proliferation and prevent infiltration of restenosis into lumen of stent. And ISR area of BMS was higher ($1.52{\pm}0.48mm^2$) than that of DES ($0.94{\pm}0.42mm^2$), indicating that paclitaxel has inhibitory effect on cell proliferation and prevent infiltration of restenosis into lumen of stent. Though it was not statistically significant, it showed that the extent of neointema of mid-region of stents was relatively higher than that of anterior and posterior region in parts of BMS as showing cross-sectional 2-D image. suggest that microCT can be utilized as an accessorial tool for pathological analysis.

The Causes of Conflict and the Effect of Control Mechanisms on Conflict Resolution between Manufacturer and Supplier (제조-공급자간 갈등 원인과 거래조정 방식의 갈등관리 효과)

  • Rhee, Jin Hwa
    • Journal of Distribution Research
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    • v.17 no.4
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    • pp.55-80
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    • 2012
  • I. Introduction Developing the relationships between companies is very important issue to ensure a competitive advantage in today's business environment (Bleeke & Ernst 1991; Mohr & Spekman 1994; Powell 1990). Partnerships between companies are based on having same goals, pursuing mutual understanding, and having a professional level of interdependence. By having such a partnerships and cooperative efforts between companies, they will achieve efficiency and effectiveness of their business (Mohr and Spekman, 1994). However, it is difficult to expect these ideal results only in the B2B corporate transaction. According to agency theory which is the well-accepted theory in various fields of business strategy, organization, and marketing, the two independent companies have fundamentally different corporate purposes. Also there is a higher chance of developing opportunism and conflict due to natures of human(organization), such as self-interest, bounded rationality, risk aversion, and environment factor as imbalance of information (Eisenhardt 1989). That is, especially partnerships between principal(or buyer) and agent(or supplier) of companies within supply chain, the business contract itself will not provide competitive advantage. But managing partnership between companies is the key to success. Therefore, managing partnership between manufacturer and supplier, and finding causes of conflict are essential to improve B2B performance. In conclusion, based on prior researches and Agency theory, this study will clarify how business hazards cause conflicts on supply chain and then identify how developed conflicts have been managed by two control mechanisms. II. Research model III. Method In order to validate our research model, this study gathered questionnaires from small and medium sized enterprises(SMEs). In Korea, SMEs mean the firms whose employee is under 300 and capital is under 8 billion won(about 7.2 million dollar). We asked the manufacturer's perception about the relationship with the biggest supplier, and our key informants are denied to a person responsible for buying(ex)CEO, executives, managers of purchasing department, and so on). In detail, we contact by telephone to our initial sample(about 1,200 firms) and introduce our research motivation and send our questionnaires by e-mail, mail, and direct survey. Finally we received 361 data and eliminate 32 inappropriate questionnaires. We use 329 manufactures' data on analysis. The purpose of this study is to identify the anticipant role of business hazard (environmental dynamism, asset specificity) and investigate the moderating effect of control mechanism(formal control, social control) on conflict-performance relationship. To find out moderating effect of control methods, we need to compare the regression weight between low versus. high group(about level of exercised control methods). Therefore we choose the structural equation modeling method that is proper to do multi-group analysis. The data analysis is performed by AMOS 17.0 software, and model fits are good statically (CMIN/DF=1.982, p<.000, CFI=.936, IFI=.937, RMSEA=.056). IV. Result V. Discussion Results show that the higher environmental dynamism and asset specificity(on particular supplier) buyer(manufacturer) has, the more B2B conflict exists. And this conflict affect relationship quality and financial outcomes negatively. In addition, social control and formal control could weaken the negative effect of conflict on relationship quality significantly. However, unlikely to assure conflict resolution effect of control mechanisms on relationship quality, financial outcomes are changed by neither social control nor formal control. We could explain this results with the characteristics of our sample, SMEs(Small and Medium sized Enterprises). Financial outcomes of these SMEs(manufacturer or principal) are affected by their customer(usually major company) more easily than their supplier(or agent). And, in recent few years, most of companies have suffered from financial problems because of global economic recession. It means that it is hard to evaluate the contribution of supplier(agent). Therefore we also support the suggestion of Gladstein(1984), Poppo & Zenger(2002) that relational performance variable can capture the focal outcomes of relationship(exchange) better than financial performance variable. This study has some implications that it tests the sources of conflict and investigates the effect of resolution methods of B2B conflict empirically. And, especially, it finds out the significant moderating effect of formal control which past B2B management studies have ignored in Korea.

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Simultaneous Multiple Transmit Focusing Method with Orthogonal Chirp Signal for Ultrasound Imaging System (초음파 영상 장치에서 직교 쳐프 신호를 이용한 동시 다중 송신집속 기법)

  • 정영관;송태경
    • Journal of Biomedical Engineering Research
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    • v.23 no.1
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    • pp.49-60
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    • 2002
  • Receive dynamic focusing with an array transducer can provide near optimum resolution only in the vicinity of transmit focal depth. A customary method to increase the depth of field is to combine several beams with different focal depths, with an accompanying decrease in the frame rate. In this Paper. we Present a simultaneous multiple transmit focusing method in which chirp signals focused at different depths are transmitted at the same time. These chirp signals are mutually orthogonal in a sense that the autocorrelation function of each signal has a narrow mainlobe width and low sidelobe levels. and the crossorelation function of any Pair of the signals has values smaller than the sidelobe levels of each autocorrelation function. This means that each chirp signal can be separated from the combined received signals and compressed into a short pulse. which is then individually focused on a separate receive beamformer. Next. the individually focused beams are combined to form a frame of image. Theoretically, any two chirp signals defined over two nonoverlapped frequency bands are mutually orthogonal In the present work. however, a tractional overlap of adjacent frequency bands is permitted to design more chirp signals within a given transducer bandwidth. The elevation of the rosscorrelation values due to the frequency overlap could be reduced by alternating the direction of frequency sweep of the adjacent chirp signals We also observe that the Proposed method provides better images when the low frequency chirp is focused at a near Point and the high frequency chirp at a far point along the depth. better lateral resolution is obtained at the far field with reasonable SNR due to the SNR gain in Pulse compression Imaging .

Evaluation of Site-specific Potential for Rice Production in Korea under the Changing Climate (지구온난화에 따른 우리나라 벼농사지대의 생산성 재평가)

  • Chung, U-Ran;Cho, Kyung-Sook;Lee, Byun-Woo
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.8 no.4
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    • pp.229-241
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    • 2006
  • Global air temperature has risen by $0.6^{\circ}C$ over the last one hundred years due to increased atmospheric greenhouse gases. Moreover, this global warming trend is projected to continue in the future. This study was carried out to evaluate spatial variations in rice production areas by simulating rice-growth and development with projected high resolution climate data in Korea far 2011-2100, which was geospatially interpolated from the 25 km gridded data based on the IPCC SRES A2 emission scenario. Satellite remote sensing data were used to pinpoint the rice-growing areas, and corresponding climate data were aggregated to represent the official 'crop reporting county'. For the simulation experiment, we used a CERES-Rice model modified by introducing two equations to calculate the leaf appearance rate based on the effective temperature and existing leaf number and the final number of leaves based on day-length in the photoperiod sensitive phase of rice. We tested the performance of this model using data-sets obtained from transplanting dates and nitrogen fertilization rates experiments over three years (2002 to 2004). The simulation results showed a good performance of this model in heading date prediction [$R^2$=0.9586 for early (Odaebyeo), $R^2$=0.9681 for medium (Hwasungbyeo), and $R^2$=0.9477 for late (Dongjinbyeo) maturity cultivars]. A modified version of CERES-Rice was used to simulate the growth and development of three Japonica varieties, representing early, medium, and late maturity classes, to project crop status for climatological normal years between 2011 and 2100. In order to compare the temporal changes, three sets of data representing 3 climatological years (2011-2040, 2041-2070, and 2071-2100) were successively used to run the model. Simulated growth and yield data of the three Japonica cultivars under the observed climate for 1971-2000 was set as a reference. Compared with the current normal, heading date was accelerated by 7 days for 2011-2040 and 20 days for 2071-2100. Physiological maturity was accelerated by 15 days for 2011-2040 and 30 days for 2071-2100. Rice yield was in general reduced by 6-25%, 3-26%, and 3-25% per 10a in early, medium, and late maturity classes, respectively. However, mid to late maturing varieties showed an increased yield in northern Gyeonggi Province and in most of Kwangwon Province in 2071-2100.

Utility of Climate Model Information For Water Resources Management in Korea

  • Jeong, Chang-Sam
    • Journal of the Korean Society of Hazard Mitigation
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    • v.8 no.6
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    • pp.37-45
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    • 2008
  • It is expected that conditions of water resources will be changed in Korea in accordance with world wide climate change. In order to deal with this problem and find a way of minimizing the effect of future climate change, the usefulness of climate model simulation information is examined in this study. The objective of this study is to assess the applicability of GCM (General Circulation Model) information for Korean water resources management through uncertainty analysis. The methods are based on probabilistic measures of the effectiveness of GCM simulations of an indicator variable for discriminating high versus low regional observations of a target variable. The formulation uses the significance probability of the Kolmogorov-Smirnov test for detecting differences between two variables. An estimator that accounts for climate model simulation and spatial association between the GCM data and observed data is used. Atmospheric general circulation model (AGCM) simulations done by ECMWF (European Centre for Medium-Range Weather Forecasts) with a resolution of $2^{\circ}{\times}2^{\circ}$, and METRI (Meteorological Research Institute, Korea) with resolutions of $2^{\circ}{\times}2^{\circ}$ and $4^{\circ}{\times}5^{\circ}$, were used for indicator variables, while observed mean areal precipitation (MAP) data, discharge data and mean areal temperature data on the seven major river basins in Korea were used for target variables. The results show that GCM simulations are useful in discriminating the high from the low of the observed precipitation, discharge, and temperature values. Temperature especially can be useful regardless of model and season.

Research Trends on Estimation of Soil Moisture and Hydrological Components Using Synthetic Aperture Radar (SAR를 이용한 토양수분 및 수문인자 산출 연구동향)

  • CHUNG, Jee-Hun;LEE, Yong-Gwan;KIM, Seong-Joon
    • Journal of the Korean Association of Geographic Information Studies
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    • v.23 no.3
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    • pp.26-67
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    • 2020
  • Synthetic Aperture Radar(SAR) is able to photograph the earth's surface regardless of weather conditions, day and night. Because of its possibility to search for hydrological factors such as soil moisture and groundwater, and its importance is gradually increasing in the field of water resources. SAR began to be mounted on satellites in the 1970s, and about 15 or more satellites were launched as of 2020, which around 10 satellites will be launched within the next 5 years. Recently, various types of SAR technologies such as enhancement of observation width and resolution, multiple polarization and multiple frequencies, and diversification of observation angles were being developed and utilized. In this paper, a brief history of the SAR system, as well as studies for estimating soil moisture and hydrological components were investigated. Up to now hydrological components that can be estimated using SAR satellites include soil moisture, subsurface groundwater discharge, precipitation, snow cover area, leaf area index(LAI), and normalized difference vegetation index(NDVI) and among them, soil moisture is being studied in 17 countries in South Korea, North America, Europe, and India by using the physical model, the IEM(Integral Equation Model) and the artificial intelligence-based ANN(Artificial Neural Network). RADARSAT-1, ENVISAT, ASAR, and ERS-1/2 were the most widely used satellite, but the operation has ended, and utilization of RADARSAT-2, Sentinel-1, and SMAP, which are currently in operation, is gradually increasing. Since Korea is developing a medium-sized satellite for water resources and water disasters equipped with C-band SAR with the goal of launching in 2025, various hydrological components estimation researches using SAR are expected to be active.

Scientific Missions and Technologies of the ISSS on board the NEXTSat-1

  • Choi, Cheong Rim;Sohn, Jongdae;Lee, Jun-Chan;Seo, Yong Myung;Kang, Suk-Bin;Ham, Jongwook;Min, Kyoung-Wook;Seon, Jongho;Yi, Yu;Chae, Jang-Soo;Shin, Goo-Hwan
    • Journal of Astronomy and Space Sciences
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    • v.31 no.1
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    • pp.73-81
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    • 2014
  • A package of space science instruments, dubbed the Instruments for the Study of Space Storms (ISSS), is proposed for the Next Generation Small Satellite-1 (NEXTSat-1), which is scheduled for launch in May 2016. This paper describes the instrument designs and science missions of the ISSS. The ISSS configuration in NEXTSat-1 is as follows: the space radiation monitoring instruments consist of medium energy particle detector (MEPD) and high energy particle detector (HEPD); the space plasma instruments consist of a Langmuir probe (LP), a retarding potential analyzer (RPA), and an ion drift meter (IDM). The space radiation monitoring instruments (MEPD and HEPD) measure electrons and protons in parallel and perpendicular directions to the geomagnetic field in the sub-auroral region, and they have a minimum time resolution of 50 msec for locating the region of the particle interactions with whistler mode waves and electromagnetic ion cyclotron (EMIC) waves. The MEPD measures electrons and protons with energies of tens of keV to ~400 keV, and the HEPD measures electrons with energies of ~100 keV to > ~1 MeV and protons with energies of ~10 MeV. The space plasma instruments (LP, RPA, and IDM) observe irregularities in the low altitude ionosphere, and the results will be compared with the scintillations of the GPS signals. In particular, the LP is designed to have a sampling rate of 50 Hz in order to detect these small-scale irregularities.

Experiments of Individual Tree and Crown Width Extraction by Band Combination Using Monthly Drone Images (월별 드론 영상을 이용한 밴드 조합에 따른 수목 개체 및 수관폭 추출 실험)

  • Lim, Ye Seul;Eo, Yang Dam;Jeon, Min Cheol;Lee, Mi Hee;Pyeon, Mu Wook
    • Journal of Korean Society for Geospatial Information Science
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    • v.24 no.4
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    • pp.67-74
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    • 2016
  • Drone images with high spatial resolution are emerging as an alternative to previous studies with extraction limits in high density forests. Individual tree in the dense forests were extracted from drone images. To detect the individual tree extracted through the image segmentation process, the image segmentation results were compared between the combination of DSM and all R,G,B band and the combination of DSM and R,G,B band separately. The changes in the tree density of a deciduous forest was experimented by time and image. Especially the image of May when the forests are dense, among the images of March, April, May, the individual tree extraction rate based on the trees surveyed on the site was 50%. The analysis results of the width of crown showed that the RMSE was less than 1.5m, which was the best result. For extraction of the experimental area, the two sizes of medium and small trees were extracted, and the extraction accuracy of the small trees was higher. The forest tree volume and forest biomass could be estimated if the tree height is extracted based on the above data and the DBH(diameter at breast height) is estimated using the relational expression between crown width and DBH.

Conflict resolution and political tasks on the usage of beauty care devices by beauty artists (미용업종사자의 미용기기 사용에 대한 분쟁해결과 정책적 과제)

  • Kim, Ju-Ri
    • Journal of Arbitration Studies
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    • v.27 no.2
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    • pp.83-105
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    • 2017
  • In contemporary society interest in and consumption of beauty treatment are increasing, raising interest in health and beauty. However, beauty-related laws are becoming factors of hindrance of beauty development. Currently the Public Health Control Act plays a basic role in the beauty art business in Korea, However the contents are in discord with international laws and its definition is not clear. Therefore it is causing conflicts of different occupations and job associations which are similar to art business. Especially, because neither definitions nor policies on beauty care devices exist in the Public Health Control Act, beauty care devices using in foreign countries cannot be used in Korea due to classification as medical devices. Under this circumstance, therefore, beauty care device uses by beauty artists violate the law. The government has tried to solve these irrational regulations. Recently, the Small and Medium Business Administration announced 'the improvement plan of small business and young founders site regulation for public economy recovery' in a ministerial meeting on December 28, 2016. Regulations on policy preparation for skincare devices were inclusive in this announcement. It is the question whether the regulations will be executed or not. Even though beauty industrial competitiveness was presented in the 18th Presidential Council on National Competitiveness in 2009, it was not practiced. The proposal bills for beauty law improvement have been put forth several times since 2000 including an improvement plan for regulating beauty care devices. However, so far there have been no improvements. The damage on the regulation classifying beauty devices as medical devices is not only restricted to skincare. This develops beauty devices and the beauty industry which imports and exports beauty devices. When beauty devices are exported, complicated procedures are unavoidable and when beauty devices are imported, irrational problems like reregistration procedures and costs occur. The reason why an improvement plan has not gone into practice is the resistance of the dermatologists' association. Dermatologists tend to stand positively against harming public health by saying that beauty devices used by beauty artists cause people to suffer side effects. In contrast, anyone who has a licence to use beauty devices is able to use them in foreign countries. It is not only infringement of one's right as a beauty artist but also people's right to receive beauty care services. With this reason, Korean's current law under which beauty devices are ruled as medical devices should be revised with accordance to domestic surroundings. Therefore in order to advance and globalize the beauty industry, the support and cooperation of the Korean government and relevant associations is needed to legislate and revise the beauty devices laws. The relevant associations abandon regional self-centeredness and cooperate to define ranges, size and management of beauty devices for safe use. If no collaboration exists, an arbitration agency should be established to solve the problem.

FIMS WAVELENGTH CALIBRATION VIA AIRGLOW LINE OBSERVATIONS (대기광 관측을 통한 과학기술위성 1호 원자외선분광기(FIMS)의 파장 보정)

  • Lee, Dae-Hee;Seon, Kwang-Il;Park, Jang-Hyun;Jin, Ho;Yuk, In-Soo;Nam, Uk-Won;Han, Won-Yong;Park, Jae-Woo;Lee, Ji-Na;Ryu, Kwang-Sun;Min, Kyoung-Wook
    • Journal of Astronomy and Space Sciences
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    • v.21 no.4
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    • pp.391-398
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    • 2004
  • Far-ultraviolet Imaging Spectrograph (FIMS) is the main payload of the Korea's first scientific micro satellite STSAT-1, which was launched at Sep. 27 2003 successfully. Major objective of FIMS is observing hot gas in the Galaxy in FUV bands to diagnose the energy flow models of the interstellar medium. Supernova remnants, molecular clouds, and Aurora emission in the geomagnetic pole regions are specific targets for pointing observation. Although the whole system was calibrated before launch, it is essential to perform on-orbit calibration for data analysis. For spectral calibration, we observed airglow lines in the atmosphere since they provide good spectral references. We identify and compare the observed airglow lines with model calculations, and correct the spectral distortion appeared in the detector system to improve the spectral resolution of the system.