• Journal of Genetic Medicine
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• v.12 no.1
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• pp.38-43
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• 2015

Purpose: Spinocerebellar ataxias (SCAs) are progressive neurodegenerative disorders with diverse modes of inheritance. There are several subtypes of SCAs. SCA 8, SCA 12, and SCA 17 are the less common forms of SCAs with limited information available on their epidemiological profiles in Korea. The purpose of this study was to investigate the prevalence of SCA8, SCA12, and SCA17 in Korea. Materials and Methods: Ninety-six unrelated Korean patients were enrolled and showed normal trinucleotide repeats through polymerase-chain reaction (PCR) for the genes ATXN1, ATXN2, ATXN3, CACNA1A, and ATXN7, which correspond to SCA1, SCA2, SCA3, SCA6, and SCA7, respectively. PCR products from patients were further analyzed by capillary electrophoresis using fluorescence labeled primers for the genes ATXN8OS, PPP2R2B, and TBP, which correspond to SCA8, SCA12, and SCA17. Results: Three patients had 104, 97, and 75 abnormal expanded repeats in the ATXN8OS gene, the causative gene for SCA8. None of the patients exhibited abnormal repeats in SCA12 and SCA17. Normal trinucleotide repeat ranges of the cohort in this study were estimated to be 17-34 copies (average, $24{\pm}4copies$) for SCA8, 7-18 copies (average, $13{\pm}3copies$) for SCA12, and 26-43 copies (average, $35{\pm}2copies$) for SCA17. Conclusion: This study demonstrated that SCA8, SCA12, and SCA17 are rare in Korean patients with SCA, and further genetic studies are warranted to enhance the mutation detection rate in the Korean SCA population.

• Journal of Acupuncture Research
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• v.21 no.1
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• pp.189-201
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• 2004

Objective: In oriental medicine, development of new formulations has been demanded. But, there are few reports about the improvement of formulations of herbal medicine in Korea. Nowadays soft Ex has been exploited and used comparing with retort pouch. This study was designed to study on preference on TongBiEum(通痺飮)/GunYoEum(健腰飮) and to investigate which OMD(oriental medical doctor) and non-OMD prefer soft Ex or retort pouch. Methods: As pilot study we administerd TongBiEum(通痺飮) once to 30 persons who serviced Gumi Oriental Medical hospital, Daegu Haany University from April 1, 2003 to April 10, 2003. And then we administerd GunYoEum(健腰飮) once to final test group(73 persons) who serviced Daegu, Gumi, Pohang Oriental Medical hospital, Daegu Haany University from April 20, 2003 to May 10, 2003. We made up questionaires about feeling during and after taking medicine, convenience and preference ect. Results: Convenience and preference of soft Ex is significantly different between OMD and non-OMD and in age bracket, but there is no significance between men and women group. Portable state of soft Ex is very convenient, dose of soft Ex is a little amount, color of soft Ex is regular in OMD & non-OMD, men & Women and an age bracket. Conclusions: From above study it was revealed that preference of herbal medicine formulations was significantly different between OMD and non-OMD. So development of new herbal medicine formulations is needed for consumers such as non-OMD.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.1
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• pp.425-429
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• 2016

Background: Dermatoscopy can be applied to diagnose pigmented skin lesions. The aim of the present study was to compare dermatoscopic and histopathologic results in basal cell carcinoma (BCC) and melanocytic nevus of theface. Materials and Methods: In an analytical-descriptive study, 61 patients suspected of BCC or melanocytic nevi of face were randomly selected. The skin lesions of patients were evaluated with dermatoscopic method from February 2012 to February 2014 and results were compared with pathological features of samples. Results: In this study, mean age of patients was $49.5{\pm}18.9$. Some 25 (41%) were men and 36 (59%) were women. In 27 cases (44.3%) there was diagnosis of melanocytic nevus, in 28 cases (45.9%) diagnosis of BCC, and in 3 cases (4.9%) there was mixed diagnosis. The relationship between patients' gender and dermatoscopic diagnosis of the patients was statistically significant (P=0.001). For BCC the sensitivity and specificity of dermatoscopic method were 100% and 97% respectively and for melanocytic nevi 96.4% and 97%. Conclusions: Dermatoscopic study not only can be helpful in improving clinical diagnosis while guiding missed malignant lesions to pathologic evaluations, but also could be useful in evaluating further suspicious or recurrent cases.

• Journal of Korean Medical classics
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• v.23 no.1
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• pp.59-79
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• 2010

Objective : We did a comparative study about characteristics of oriental medical books. As a result, we took notice of classification in the nominal terms by semantic type of UMLS(Unified Medical Language System). By using classified nominal terms, comparative study can be more effectively. So, we selected another oriental medical book and classified nominal terms in it by semantic type of UMLS. By result of classification, we have attempted to study about comparison between oriental medical books and development of medical theories. Method :We have made a comparative study on classification in the nominal terms between "Biwiron(脾胃論)" and "Soayakjeungjikgyeol(小兒藥證直訣)" according to the below the procedure. (1) Making a nominal terms list of "Soayakjeungjikgyeol(小兒藥證直訣)" and grasping contextual meaning of nominal terms of it. (2) Modification and supplementation about semantic type of UMLS for "Soayakjeungjikgyeol(小兒藥證直訣)". Using the modified classification system, we classified nominal terms. After this process, we arranged classified nominal terms by Haansoft Hangul 2007. (3) Comparing classified nominal terms between "Biwiron(脾胃論)" and "Soayakjeungjikgyeol(小兒藥證直訣)". Result : In the "Soayakjeungjikgyeol(小兒藥證直訣)", there are more than 2,519's nominal terms and different categories of semantic type of UMLS classification from "Biwiron(脾胃論)". Through comparison between their classification of nominal terms, we can understand the characteristics of the two and their development of medical theories.

• The Journal of Korean Medical History
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• v.26 no.1
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• pp.9-18
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• 2013

This study examines the meaning of classical texts in contemporary society. Drawing on an anthropological investigation of Somun Hakhoe, an association of Korean medicine doctors in South Korea, and its foundational text "Somun Daeyo", the present study explores the interconnectedness of medical texts and medico-social practices in bringing medical tradition into the contemporary era. The themes that author Lee Kyu-joon emphasizes in "Somun Daeyo" are thoroughly embodied in Somun Hakhoe's medico-social practices, such as the study activities based on "Somun Daeyo"(in particular, on Somun Buseol, the five articles written by the author, attached to "Somun Daeyo"), the focus on Buyang theory(扶陽論), and the distinctive feature of composing formula. The ethnographic data collected about the group activities of Somun Hakhoe also demonstrate that the social relationship of the teacher and disciples plays an important role in bringing East Asian medicine into the present. This study articulates the significance of the interaction between the classical text and the medico-social practices around it. The dynamism taking place in the interaction points to the "living tradition" actively flowing rather than being static in the past. This study illustrates the close relationship between medical history and medical anthropology and encourages more studies of classical texts based on the intimate relationship between the two disciplines.

• Journal of Convergence Korean Medicine
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• v.6 no.1
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• pp.37-42
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• 2024

Objectives: This study aims to evaluate the clinical validity of the system by conducting a clinical study to assess the diagnostic agreement between the system and Korean medical doctors. Methods: This study was conducted from September 7, 2023, to December 7, 2023, across five Korean medicine institutions, involving 100 adult participants aged 20-64 who consented to participate. Participants first entered their symptoms into a web-based program, which utilized an AI-based algorithm to diagnose 36 types of pattern differentiation. Subsequently, Korean medical doctors conducted face-to-face diagnoses using the same 36 types. The diagnostic agreement between the system and the doctors' diagnoses was analyzed using descriptive statistical analysis, and the results were expressed as a percentage agreement. Results: Analysis of the diagnostic data from 100 participants revealed that the web-based diagnosis support system identified an average of 7.76±0.79 patterns per patient, while Korean medical doctors identified an average of 7.99±0.10 patterns per patient. The diagnostic agreement between the system and the doctors showed an average of 7.08±1.08 patterns per patient, with an overall diagnostic agreement rate of 88.57±13.31%. Conclusion: This study developed a web-based diagnosis support system for traditional Korean medicine and evaluated its clinical validity by assessing diagnostic agreement. Comparing the diagnoses of the system with those of Korean medical doctors for 100 patients, the system showed an approximately 89% agreement rate with the clinical diagnoses. The system holds potential for aiding Korean medical doctors in pattern differentiation diagnosis in clinical practice.

• The Korean Journal of Emergency Medical Services
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• v.7 no.1
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• pp.135-146
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• 2003

The purpose of this study was to improve EMS-System in Korea through the research in EMS-System of advanced country. The response time is defined as the interval from the time of call receipt to the time of scene arrival. The important factor was to shorten moving distance of ambulance. It should be considered to accomplish this factor that the vehicle must be increased and the convenient location chosen for optimizing of service area. The transport of emergency patients carried out almost by 119 Emergency Medical Service but out of all the employees at 119 EMS only 11.3% have own qualified EMT degree. They should be employed more and more specially at 119 EMS for a superior level of emergency medical care for civilian. In America, EMT can take care of emergency patients following the order from medical Director at the scene of accident. But in Germany, prehospital care was emphasized from the beginning and, in those days, a medical doctor was sent for treatment of emergency patients at the scene, the so-called a Rendezvous system. Hierby this study makes the suggestion to improve the EMS-System, it is effective to use the medical Director system in America and furthermore a Rendezvous system in Germany. The functional integratin and unification of the report system as well as enough personal and equipmental elements saved together invaluable lives.

• KIEAE Journal
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• v.17 no.1
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• pp.55-61
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• 2017

Purpose : As the necessity of reinforcement of infections management in medical facilities after MERS increased, Ministry of Health and Welfare promulgated the enforcement regulations of medical law on February 3, 2017. Its main objective is to improve patients' safety and medical-care quality through the establishment of isolation facilities from infectious diseases and the set-up of standards for In-patient and ICU facilities. The purpose of this study is necessarily to propose a standardized spatial composition model for ward modules by analyzing changing environments of in-patient facilities according to the strengthened medical law. Method: Theoretical studies will be undergone of Evidence-based Designs to improve patients' safety, medical quality, and domestic/overseas in-patient room guidelines. With reference to the status of 24 general hospitals over 500 beds, the spatial compositions of the in-patient rooms and the types of multi/single bed room modules will be analyzed. The directions of future in-patient room module changes through the study of the minimum ward module types and various ward types will be presented. Result: This paper will hopefully provide guidelines for hospitalization rooms that can be applied to the revised rules of medical law enforcement and provide a basis for a comprehensive study of patients' safety and efficient infection control as well.

• The Korean Journal of Emergency Medical Services
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• v.8 no.1
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• pp.141-148
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• 2004

The purpose of this study which was done by questionnaire survey on doctors, paramedics, radio operators, computer technicians, administrators in Emergency Medical Care Information Centers was to analyze demand on EMD education. The significant 101 data were collected in 12 Emergency Medical Care Information Centers from Dec. 17, 2003 to Jan. 31, 2004 and analyzed by using SPSS. The conclusions from this study were summarized as follows. Composition of respondents who work in Emergency Medical Care Information Centers were 40.7% 26-30 years old in age, 56.4% male in sex, 55.6% medical direction in duty, 76.2% paramedics in certificate. 54.5% out of the paramedics had two years present career, 62.3% had one year past career, 31.0% didn't receive EMD education, 39.0% wanted 5-8 hours continuing education. The paramedics received more EMD education on Introduction to Emergency Medical Concepts, Obtaining Information from Callers, Providing Emergency Care Instructions and wanted more continuing education on Providing Emergency Care Instructions, Key Questions & Pre-Arrival Instructions, Obtaining Information from Callers. This study will be helpful to build up an education system for EMDs such as continuing education, curriculum, certification.

• Korean Medical Education Review
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• v.22 no.2
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• pp.57-66
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• 2020

The purpose of this study was to examine teaching strategies from cognitive learning theory applied to medical education and to present specific applications of the strategies and cases. The results of this study yielded (1) seven teaching strategies and specific sample activities that instructors can use based on learning processes in medical schools; (2) nine instructional events to which cognitive learning strategies were applied; (3) principles of curriculum design from a cognitive perspective; and (4) instruction cases employing cognitive teaching strategies. Cognitive learning theory has two implications: first, if instructors in medical schools apply the results of the study to design a class and curriculum, it would be possible for them to minimize cognitive loading of the learners that may stem from ineffective teaching strategies or curricula; second, cognitive teaching strategies that seek improvement in thinking skills could provide useful teaching strategies for medical education, which aims to develop experts with high-level thinking processes. In this sense, cognitive learning theory is not an out-of-date learning theory, but one that can be effectively applied in current medical education.